MGE detailed information
MGE type: Conjugative plasmid MGE length: 120320 bp
Accession: NZ_CP074020 Location: 1..120320 Organism: Escherichia coli strain PM22 Replicon: plasmid pYLPM22a
Accession: NZ_CP074020 Location: 1..120320 Organism: Escherichia coli strain PM22 Replicon: plasmid pYLPM22a
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFU87_RS23005 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| KFU87_RS23010 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| KFU87_RS23015 (2124) | 2124..2312 | - | 189 | WP_001324033.1 | hypothetical protein | - |
| KFU87_RS23020 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| KFU87_RS23025 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| KFU87_RS23030 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | hypothetical protein | VF |
| KFU87_RS23035 (7450) | 7450..7629 | - | 180 | Protein_6 | transposase | - |
| KFU87_RS23040 (7768) | 7768..8981 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| KFU87_RS23045 (9129) | 9129..9397 | - | 269 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| KFU87_RS23050 (9454) | 9454..10151 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| KFU87_RS23055 (10168) | 10168..10365 | - | 198 | Protein_10 | colicin V | - |
| KFU87_RS23060 (10343) | 10343..10579 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| KFU87_RS23065 (11121) | 11121..11324 | - | 204 | Protein_12 | hypothetical protein | - |
| KFU87_RS23070 (11497) | 11497..11664 | + | 168 | Protein_13 | colicin-B | - |
| KFU87_RS23075 (11682) | 11682..12209 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| KFU87_RS23080 (12453) | 12453..13268 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| KFU87_RS23085 (13318) | 13318..13671 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| KFU87_RS23090 (13849) | 13849..14640 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| KFU87_RS23095 (14637) | 14637..15326 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| KFU87_RS23100 (15370) | 15370..15720 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| KFU87_RS23105 (16265) | 16265..17353 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| KFU87_RS23110 (17355) | 17355..19580 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| KFU87_RS23115 (19630) | 19630..20529 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| KFU87_RS23120 (20519) | 20519..20809 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| KFU87_RS23125 (21105) | 21105..21335 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| KFU87_RS23130 (21332) | 21332..21748 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KFU87_RS23135 (21910) | 21910..24048 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| KFU87_RS23140 (24402) | 24402..24659 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| KFU87_RS23145 (24659) | 24659..25249 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| KFU87_RS23150 (25512) | 25512..26972 | + | 1461 | WP_202745975.1 | AAA family ATPase | - |
| KFU87_RS23155 (27260) | 27260..27877 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| KFU87_RS23160 (28275) | 28275..29537 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| KFU87_RS23165 (29793) | 29793..30668 | + | 876 | WP_015387340.1 | hypothetical protein | ARG |
| KFU87_RS23170 (30715) | 30715..31008 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| KFU87_RS23175 (31225) | 31225..32304 | - | 1080 | WP_001089727.1 | permease | - |
| KFU87_RS23180 (32409) | 32409..32732 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFU87_RS23185 (32893) | 32893..33213 | + | 321 | Protein_36 | NAD(P)H-dependent oxidoreductase | - |
| KFU87_RS23190 (33266) | 33266..33970 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KFU87_RS23195 (34036) | 34036..35550 | + | 1515 | Protein_38 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| KFU87_RS23200 (35608) | 35608..35850 | + | 243 | WP_000844627.1 | transposase | - |
| KFU87_RS23205 (35882) | 35882..36532 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| KFU87_RS23210 (36638) | 36638..37837 | + | 1200 | WP_077248803.1 | Multidrug resistance protein MdtG | ARG |
| KFU87_RS23215 (37869) | 37869..38753 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| KFU87_RS23220 (38891) | 38891..39283 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| KFU87_RS23225 (39287) | 39287..40855 | + | 1569 | Protein_44 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| KFU87_RS23230 (40908) | 40908..41612 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KFU87_RS23235 (41678) | 41678..41962 | + | 285 | Protein_46 | IS6 family transposase IS26 | Transposase |
| KFU87_RS23240 (42152) | 42152..42967 | - | 816 | WP_000018329.1 | hypothetical protein | ARG |
| KFU87_RS23245 (43118) | 43118..43822 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KFU87_RS23250 (43875) | 43875..44672 | - | 798 | Protein_49 | IS91 family transposase ISAzo26 | Transposase |
| KFU87_RS23255 (44821) | 44821..45659 | + | 839 | Protein_50 | hypothetical protein | ARG |
| KFU87_RS23260 (45744) | 45744..46565 | + | 822 | WP_000939727.1 | hypothetical protein | ARG |
| KFU87_RS23265 (46718) | 46718..47422 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KFU87_RS23270 (47476) | 47476..48524 | - | 1049 | Protein_53 | IS3 family transposase ISKpn11 | Transposase |
| KFU87_RS23275 (48616) | 48616..49158 | - | 543 | WP_002063889.1 | AAA family ATPase | - |
| KFU87_RS23280 (49171) | 49171..50031 | - | 861 | WP_000557452.1 | hypothetical protein | ARG |
| KFU87_RS23285 (50138) | 50138..50842 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KFU87_RS23290 (50908) | 50908..51453 | + | 546 | Protein_57 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KFU87_RS23295 (51489) | 51489..51904 | - | 416 | Protein_58 | IS1 family transposase | - |
| KFU87_RS23300 (52153) | 52153..52554 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| KFU87_RS23305 (52487) | 52487..52744 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| KFU87_RS23310 (52837) | 52837..53490 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| KFU87_RS23315 (53588) | 53588..53728 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| KFU87_RS23320 (54429) | 54429..55286 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| KFU87_RS23325 (55279) | 55279..55761 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| KFU87_RS23330 (55754) | 55754..55801 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| KFU87_RS23335 (55792) | 55792..56043 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| KFU87_RS23340 (56060) | 56060..56317 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| KFU87_RS23345 (56601) | 56601..56750 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (56794) | 56794..56855 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (56794) | 56794..56855 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (56794) | 56794..56855 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (56794) | 56794..56855 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| KFU87_RS23350 (57111) | 57111..57185 | - | 75 | Protein_69 | endonuclease | - |
| KFU87_RS23355 (57431) | 57431..57643 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| KFU87_RS23360 (57779) | 57779..58339 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| KFU87_RS23365 (58442) | 58442..59302 | - | 861 | WP_000704513.1 | hypothetical protein | VF |
| KFU87_RS23370 (59361) | 59361..60107 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| KFU87_RS23375 (60127) | 60127..65397 | - | 5271 | WP_000986962.1 | ATP-dependent RecD-like DNA helicase | Relaxase |
| KFU87_RS23380 (65479) | 65479..65706 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| KFU87_RS23385 (65706) | 65706..66104 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KFU87_RS23390 (66113) | 66113..68266 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| KFU87_RS23395 (68519) | 68519..69229 | - | 711 | WP_230133085.1 | conjugal transfer complement resistance protein TraT | - |
| KFU87_RS23400 (69282) | 69282..69779 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| KFU87_RS23405 (69795) | 69795..72617 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| KFU87_RS23410 (72614) | 72614..73987 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| KFU87_RS23415 (73987) | 73987..74367 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| KFU87_RS23420 (74354) | 74354..74695 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| KFU87_RS23425 (74625) | 74625..75170 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| KFU87_RS23430 (75157) | 75157..75441 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| KFU87_RS23435 (75522) | 75522..75836 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| KFU87_RS23440 (75838) | 75838..76185 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| KFU87_RS23445 (76201) | 76201..76944 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| KFU87_RS23450 (76937) | 76937..77194 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| KFU87_RS23455 (77221) | 77221..79029 | - | 1809 | WP_257182346.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| KFU87_RS23460 (79026) | 79026..79664 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| KFU87_RS23465 (79673) | 79673..80665 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| KFU87_RS23470 (80662) | 80662..81294 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| KFU87_RS23475 (81291) | 81291..81677 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| KFU87_RS23480 (81674) | 81674..84301 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| KFU87_RS23485 (84461) | 84461..84682 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| KFU87_RS23490 (84817) | 84817..85332 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| KFU87_RS23495 (85329) | 85329..85580 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| KFU87_RS23500 (85592) | 85592..85789 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| KFU87_RS23505 (85776) | 85776..86366 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| KFU87_RS23510 (86356) | 86356..87783 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| KFU87_RS23515 (87783) | 87783..88511 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| KFU87_RS23520 (88498) | 88498..89064 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| KFU87_RS23525 (89086) | 89086..89397 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| KFU87_RS23530 (89412) | 89412..89777 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| KFU87_RS23535 (89810) | 89810..90211 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| KFU87_RS23540 (90304) | 90304..90993 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| KFU87_RS23545 (91180) | 91180..91563 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| KFU87_RS23550 (91884) | 91884..92486 | + | 603 | WP_072156291.1 | hypothetical protein | VF |
| KFU87_RS23555 (92783) | 92783..93604 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| KFU87_RS23560 (93723) | 93723..94010 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| KFU87_RS23565 (94035) | 94035..94241 | - | 207 | WP_000547971.1 | hypothetical protein | - |
| KFU87_RS23570 (94311) | 94311..94484 | + | 174 | Protein_113 | hypothetical protein | - |
| KFU87_RS23575 (94482) | 94482..94712 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| KFU87_RS23580 (94932) | 94932..95057 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| KFU87_RS23585 (94999) | 94999..95148 | - | 150 | Protein_116 | plasmid maintenance protein Mok | - |
| - (95134) | 95134..95358 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (95134) | 95134..95358 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (95134) | 95134..95358 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (95134) | 95134..95358 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| KFU87_RS23590 (95170) | 95170..95358 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| KFU87_RS23595 (95327) | 95327..96089 | - | 763 | Protein_118 | plasmid SOS inhibition protein A | - |
| KFU87_RS23600 (96086) | 96086..96520 | - | 435 | WP_064770609.1 | conjugation system SOS inhibitor PsiB | - |
| KFU87_RS23605 (96575) | 96575..96772 | - | 198 | Protein_120 | hypothetical protein | - |
| KFU87_RS23610 (96800) | 96800..97033 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| KFU87_RS23615 (97101) | 97101..97640 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| KFU87_RS23620 (97666) | 97666..97872 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| KFU87_RS23625 (97942) | 97942..98022 | + | 81 | Protein_124 | hypothetical protein | - |
| KFU87_RS23630 (98205) | 98205..98374 | - | 170 | Protein_125 | hypothetical protein | - |
| KFU87_RS23635 (98968) | 98968..99939 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| KFU87_RS23640 (99939) | 99939..101105 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| KFU87_RS23650 (102587) | 102587..104788 | - | 2202 | WP_000973520.1 | Vitamin B12 transporter BtuB | VF |
| KFU87_RS23655 (104814) | 104814..106147 | - | 1334 | Protein_130 | Ferredoxin--NADP reductase | VF |
| KFU87_RS23660 (106144) | 106144..107886 | - | 1743 | WP_001015721.1 | hypothetical protein | VF |
| KFU87_RS23665 (107886) | 107886..108833 | - | 948 | WP_000011910.1 | hypothetical protein | VF |
| KFU87_RS23670 (108834) | 108834..110558 | - | 1725 | WP_000602863.1 | hypothetical protein | VF |
| KFU87_RS23675 (110694) | 110694..111887 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| KFU87_RS23680 (112267) | 112267..112647 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| KFU87_RS23685 (112988) | 112988..113401 | - | 414 | Protein_136 | phosphopyruvate hydratase | - |
| KFU87_RS23690 (113399) | 113399..113656 | + | 258 | Protein_137 | transposase | - |
| KFU87_RS23695 (113890) | 113890..114747 | - | 858 | WP_000968139.1 | hypothetical protein | ARG |
| KFU87_RS23700 (114744) | 114744..115601 | - | 858 | WP_001101723.1 | hypothetical protein | ARG |
| KFU87_RS23705 (115598) | 115598..116425 | - | 828 | WP_000983710.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| KFU87_RS23710 (116425) | 116425..117339 | - | 915 | WP_000949004.1 | hypothetical protein | ARG |
| KFU87_RS23715 (117695) | 117695..118392 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| KFU87_RS23720 (118572) | 118572..119085 | - | 514 | Protein_143 | DUF4113 domain-containing protein | - |
| KFU87_RS23725 (119146) | 119146..119250 | - | 105 | Protein_144 | AAA family ATPase | - |
| KFU87_RS23730 (119252) | 119252..119575 | - | 324 | Protein_145 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|