MGE detailed information
MGE type: Conjugative plasmid MGE length: 131034 bp
Accession: NZ_CP069883 Location: 1..131034 Organism: Escherichia coli strain FDAARGOS_1289 Replicon: plasmid unnamed1
Accession: NZ_CP069883 Location: 1..131034 Organism: Escherichia coli strain FDAARGOS_1289 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6K19_RS24740 (140) | 140..3934 | + | 3795 | WP_001144732.1 | hypothetical protein | - |
| I6K19_RS24745 (3979) | 3979..4395 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| I6K19_RS24750 (4392) | 4392..4622 | - | 231 | WP_001261278.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| I6K19_RS24755 (4887) | 4887..5387 | + | 501 | WP_000528931.1 | HEPN family nuclease | - |
| I6K19_RS24760 (5400) | 5400..6173 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| I6K19_RS24765 (6406) | 6406..7977 | - | 1572 | WP_000381395.1 | IS66 family transposase ISCro1 | Transposase |
| I6K19_RS24770 (7997) | 7997..8344 | - | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| I6K19_RS24775 (8344) | 8344..9021 | - | 678 | WP_001299364.1 | IS66 family transposase ISCro1 | Transposase |
| I6K19_RS24780 (9062) | 9062..10180 | + | 1119 | WP_204606457.1 | hypothetical protein | - |
| I6K19_RS24785 (10214) | 10214..10702 | - | 489 | WP_011254646.1 | hypothetical protein | - |
| I6K19_RS24790 (11293) | 11293..11511 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| I6K19_RS24795 (11513) | 11513..11818 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| I6K19_RS24800 (11819) | 11819..12625 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| I6K19_RS24805 (13399) | 13399..14154 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| I6K19_RS24810 (14393) | 14393..15043 | + | 651 | WP_000993931.1 | IS66 family transposase IS679 | Transposase |
| I6K19_RS24815 (15043) | 15043..15390 | + | 348 | WP_097455558.1 | IS66 family transposase ISCro1 | Transposase |
| I6K19_RS24820 (15410) | 15410..16981 | + | 1572 | WP_000381416.1 | IS66 family transposase IS679 | Transposase |
| I6K19_RS24825 (17455) | 17455..18621 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| I6K19_RS24830 (18621) | 18621..19592 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| I6K19_RS24835 (20459) | 20459..21361 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| I6K19_RS24840 (21358) | 21358..21669 | + | 312 | WP_011254640.1 | hypothetical protein | - |
| I6K19_RS24845 (21746) | 21746..22429 | + | 684 | WP_000086185.1 | DNA methylase | - |
| I6K19_RS24850 (22430) | 22430..22651 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| I6K19_RS24855 (22581) | 22581..23099 | + | 519 | WP_123325260.1 | DUF1380 family protein | - |
| I6K19_RS24860 (23150) | 23150..23926 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| I6K19_RS24865 (24343) | 24343..24768 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| I6K19_RS24870 (24738) | 24738..25232 | + | 495 | WP_235166619.1 | DUF1380 domain-containing protein | - |
| I6K19_RS24875 (25229) | 25229..25420 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| I6K19_RS24880 (25693) | 25693..25941 | - | 249 | WP_071556315.1 | hypothetical protein | - |
| I6K19_RS24885 (26455) | 26455..26685 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| I6K19_RS24890 (26737) | 26737..28098 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| I6K19_RS24895 (28146) | 28146..28709 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| I6K19_RS24900 (28735) | 28735..28959 | + | 225 | WP_016238251.1 | hypothetical protein | - |
| I6K19_RS27225 (28860) | 28860..29129 | + | 270 | WP_071977877.1 | hypothetical protein | - |
| I6K19_RS24905 (29122) | 29122..29457 | + | 336 | WP_013023883.1 | hypothetical protein | - |
| I6K19_RS27230 (29370) | 29370..29576 | + | 207 | WP_000547975.1 | hypothetical protein | - |
| I6K19_RS24910 (29602) | 29602..30141 | + | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| I6K19_RS24915 (30204) | 30204..30437 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| I6K19_RS24920 (30503) | 30503..32461 | + | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| I6K19_RS24925 (32516) | 32516..32950 | + | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| I6K19_RS24930 (32947) | 32947..33709 | + | 763 | Protein_40 | plasmid SOS inhibition protein A | - |
| - (33678) | 33678..33779 | + | 102 | NuclAT_1 | - | - |
| - (33678) | 33678..33779 | + | 102 | NuclAT_1 | - | - |
| - (33678) | 33678..33779 | + | 102 | NuclAT_1 | - | - |
| - (33678) | 33678..33779 | + | 102 | NuclAT_1 | - | - |
| I6K19_RS24935 (33825) | 33825..35194 | + | 1370 | WP_085947770.1 | IS3 family transposase IS150 | Transposase |
| - (35221) | 35221..35348 | + | 128 | NuclAT_0 | - | - |
| - (35221) | 35221..35348 | + | 128 | NuclAT_0 | - | - |
| - (35221) | 35221..35348 | + | 128 | NuclAT_0 | - | - |
| - (35221) | 35221..35348 | + | 128 | NuclAT_0 | - | - |
| I6K19_RS27235 (35334) | 35334..35483 | + | 150 | Protein_42 | plasmid maintenance protein Mok | - |
| I6K19_RS24940 (35425) | 35425..35550 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| I6K19_RS27240 (35770) | 35770..36000 | + | 231 | WP_001426396.1 | hypothetical protein | - |
| I6K19_RS27245 (35998) | 35998..36171 | - | 174 | Protein_45 | hypothetical protein | - |
| I6K19_RS24950 (36241) | 36241..36501 | + | 261 | WP_250187944.1 | single-stranded DNA-binding protein | - |
| I6K19_RS24955 (36595) | 36595..37599 | - | 1005 | WP_204606458.1 | IS110 family transposase IS1663 | Transposase |
| I6K19_RS24960 (37850) | 37850..38137 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| I6K19_RS24965 (38257) | 38257..39078 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| I6K19_RS24970 (39375) | 39375..39965 | - | 591 | WP_277996679.1 | hypothetical protein | VF |
| I6K19_RS24975 (40308) | 40308..40691 | + | 384 | WP_001151566.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| I6K19_RS24980 (40825) | 40825..41502 | + | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| I6K19_RS24985 (41590) | 41590..41817 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| I6K19_RS24990 (41851) | 41851..42213 | + | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| I6K19_RS24995 (42218) | 42218..42529 | + | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| I6K19_RS25000 (42551) | 42551..43117 | + | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| I6K19_RS25005 (43104) | 43104..43832 | + | 729 | WP_001230808.1 | type-F conjugative transfer system secretin TraK | - |
| I6K19_RS25010 (43832) | 43832..45283 | + | 1452 | WP_000146687.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| I6K19_RS25015 (45273) | 45273..45839 | + | 567 | WP_000896601.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| I6K19_RS25020 (45826) | 45826..46137 | + | 312 | WP_001057272.1 | conjugal transfer protein TrbD | - |
| I6K19_RS25025 (46137) | 46137..46652 | + | 516 | WP_000809886.1 | type IV conjugative transfer system lipoprotein TraV | - |
| I6K19_RS25030 (46787) | 46787..47008 | + | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| I6K19_RS25035 (47168) | 47168..49795 | + | 2628 | WP_001064258.1 | type IV secretion system protein TraC | - |
| I6K19_RS25040 (49792) | 49792..50178 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| I6K19_RS25045 (50175) | 50175..50807 | + | 633 | WP_001203727.1 | type-F conjugative transfer system protein TraW | - |
| I6K19_RS25050 (50804) | 50804..51796 | + | 993 | WP_000830190.1 | conjugal transfer pilus assembly protein TraU | - |
| I6K19_RS25055 (51826) | 51826..52131 | + | 306 | WP_000224413.1 | hypothetical protein | - |
| I6K19_RS25060 (52140) | 52140..52778 | + | 639 | WP_001080259.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| I6K19_RS25065 (52775) | 52775..54625 | + | 1851 | WP_000821866.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| I6K19_RS25070 (54652) | 54652..54909 | + | 258 | WP_000864347.1 | conjugal transfer protein TrbE | - |
| I6K19_RS25075 (54902) | 54902..55645 | + | 744 | WP_001030401.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| I6K19_RS25080 (55775) | 55775..56755 | + | 981 | WP_000019450.1 | IS5 family transposase ISKpn26 | Transposase |
| I6K19_RS25085 (56910) | 56910..57607 | + | 698 | WP_223216367.1 | IS1 family transposase IS1G | Transposase |
| I6K19_RS25090 (57655) | 57655..57975 | + | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| I6K19_RS25095 (58102) | 58102..58386 | + | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| I6K19_RS25100 (58373) | 58373..58918 | + | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| I6K19_RS25105 (58848) | 58848..59195 | + | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| I6K19_RS25110 (59176) | 59176..59568 | + | 393 | WP_000659962.1 | F-type conjugal transfer protein TrbF | - |
| I6K19_RS25115 (59555) | 59555..60928 | + | 1374 | WP_000944328.1 | conjugal transfer pilus assembly protein TraH | - |
| I6K19_RS25120 (60925) | 60925..63744 | + | 2820 | WP_001007062.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| I6K19_RS25125 (63763) | 63763..64260 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| I6K19_RS25130 (64292) | 64292..65023 | + | 732 | WP_000850429.1 | conjugal transfer complement resistance protein TraT | - |
| I6K19_RS25135 (65226) | 65226..66005 | + | 780 | WP_000199914.1 | hypothetical protein | - |
| I6K19_RS25140 (66002) | 66002..68164 | + | 2163 | WP_023144755.1 | type IV conjugative transfer system coupling protein TraD | - |
| I6K19_RS25145 (68164) | 68164..73434 | + | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| I6K19_RS25150 (73454) | 73454..74200 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| I6K19_RS25155 (74255) | 74255..74815 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| I6K19_RS25160 (74946) | 74946..75158 | + | 213 | WP_013023861.1 | hypothetical protein | - |
| I6K19_RS25165 (75671) | 75671..75957 | + | 287 | Protein_89 | DUF2726 domain-containing protein | - |
| - (75924) | 75924..75984 | - | 61 | NuclAT_2 | - | - |
| - (75924) | 75924..75984 | - | 61 | NuclAT_2 | - | - |
| - (75924) | 75924..75984 | - | 61 | NuclAT_2 | - | - |
| - (75924) | 75924..75984 | - | 61 | NuclAT_2 | - | - |
| I6K19_RS25170 (76029) | 76029..76163 | + | 135 | WP_023144756.1 | Hok/Gef family protein | - |
| I6K19_RS25175 (76460) | 76460..76714 | + | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| I6K19_RS25185 (76951) | 76951..77025 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| I6K19_RS25190 (77018) | 77018..77875 | + | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| I6K19_RS25195 (78031) | 78031..79570 | - | 1540 | Protein_94 | IS66 family transposase ISEc22 | Transposase |
| I6K19_RS25200 (79619) | 79619..79966 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| I6K19_RS25205 (79963) | 79963..80367 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| I6K19_RS25210 (81255) | 81255..81524 | + | 270 | WP_000079939.1 | type II toxin-antitoxin system antitoxin YacA | - |
| I6K19_RS25215 (81524) | 81524..81634 | + | 111 | Protein_98 | type II toxin-antitoxin system toxin YacB | - |
| I6K19_RS25220 (81733) | 81733..82656 | + | 924 | WP_001415483.1 | hypothetical protein | - |
| I6K19_RS25225 (83098) | 83098..83478 | + | 381 | WP_001696636.1 | HTH domain-containing protein | - |
| I6K19_RS25230 (83590) | 83590..83994 | + | 405 | Protein_101 | IS91 family transposase ISPps1 | Transposase |
| I6K19_RS25235 (84101) | 84101..84937 | - | 837 | WP_000480972.1 | hypothetical protein | ARG |
| I6K19_RS25240 (84937) | 84937..85740 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| I6K19_RS25245 (85801) | 85801..86616 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| I6K19_RS25250 (86953) | 86953..87156 | + | 204 | WP_000131876.1 | hypothetical protein | - |
| I6K19_RS25255 (87147) | 87147..87368 | + | 222 | WP_001251694.1 | hypothetical protein | - |
| I6K19_RS25260 (87603) | 87603..87962 | - | 360 | WP_000050069.1 | hypothetical protein | - |
| I6K19_RS25265 (88119) | 88119..88979 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| I6K19_RS25270 (89270) | 89270..89974 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| I6K19_RS25275 (90070) | 90070..90579 | + | 510 | WP_000571065.1 | Dihydrofolate reductase | ARG |
| I6K19_RS25280 (90576) | 90576..91232 | + | 657 | WP_000144779.1 | metallophosphoesterase | - |
| I6K19_RS25285 (91269) | 91269..91346 | + | 78 | Protein_112 | IS6 family transposase | - |
| I6K19_RS25290 (91404) | 91404..92101 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| I6K19_RS25295 (92108) | 92108..92308 | + | 201 | Protein_114 | amino acid-binding protein | - |
| I6K19_RS25300 (92316) | 92316..93002 | + | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| I6K19_RS25305 (92980) | 92980..93603 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| I6K19_RS25310 (93685) | 93685..94890 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| I6K19_RS25315 (95003) | 95003..95596 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| I6K19_RS25325 (96619) | 96619..96732 | + | 114 | Protein_120 | IS6 family transposase | - |
| I6K19_RS25330 (96870) | 96870..97040 | + | 171 | Protein_121 | DsbA family protein | - |
| I6K19_RS25335 (97030) | 97030..97536 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| I6K19_RS25340 (97719) | 97719..98534 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| I6K19_RS25345 (98881) | 98881..100767 | + | 1887 | WP_000118029.1 | FTR1 family protein | - |
| I6K19_RS25350 (100808) | 100808..101335 | + | 528 | WP_000178050.1 | iron transporter | - |
| I6K19_RS25355 (101439) | 101439..102818 | + | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| I6K19_RS25360 (102821) | 102821..104104 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| I6K19_RS25365 (104094) | 104094..105224 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| I6K19_RS25370 (105229) | 105229..105924 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| I6K19_RS25375 (105911) | 105911..106396 | + | 486 | WP_001267177.1 | TlpA disulfide reductase family protein | - |
| I6K19_RS25380 (106421) | 106421..106906 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| I6K19_RS25385 (107028) | 107028..107558 | + | 531 | Protein_132 | histidine-type phosphatase | - |
| I6K19_RS25390 (107616) | 107616..108320 | - | 705 | WP_001067834.1 | IS3 family transposase IS1203 | Transposase |
| I6K19_RS25395 (108345) | 108345..109541 | + | 1197 | Protein_134 | IS3 family transposase | - |
| I6K19_RS25400 (109581) | 109581..109796 | + | 216 | Protein_135 | Tn3 family transposase ISPsy39 | Transposase |
| I6K19_RS25405 (109873) | 109873..110181 | + | 309 | Protein_136 | IS4 family transposase ISEc13 | Transposase |
| I6K19_RS25410 (110240) | 110240..111550 | - | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| I6K19_RS25415 (111543) | 111543..112616 | - | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| I6K19_RS25420 (112622) | 112622..113446 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| I6K19_RS25425 (113457) | 113457..114344 | - | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| I6K19_RS25430 (114334) | 114334..115212 | - | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| I6K19_RS25435 (115343) | 115343..115783 | - | 441 | Protein_142 | zinc-binding dehydrogenase | - |
| I6K19_RS25440 (116184) | 116184..117074 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| I6K19_RS25445 (117099) | 117099..117479 | + | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| I6K19_RS25450 (117512) | 117512..118477 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| I6K19_RS25455 (118523) | 118523..119275 | - | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| I6K19_RS25460 (119880) | 119880..120164 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| I6K19_RS25465 (120164) | 120164..120439 | + | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| I6K19_RS25470 (120545) | 120545..120748 | + | 204 | Protein_149 | hypothetical protein | - |
| I6K19_RS25475 (120873) | 120873..121001 | - | 129 | Protein_150 | IS481 family transposase | - |
| I6K19_RS25480 (121034) | 121034..122203 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| I6K19_RS27250 (122300) | 122300..122572 | + | 273 | Protein_152 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| I6K19_RS25485 (122639) | 122639..122821 | + | 183 | WP_042344623.1 | hypothetical protein | - |
| I6K19_RS25490 (122942) | 122942..123682 | + | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| I6K19_RS25495 (123967) | 123967..124944 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| I6K19_RS25500 (125690) | 125690..126013 | + | 324 | Protein_156 | IS21 family transposase IS21 | Transposase |
| I6K19_RS25505 (126015) | 126015..126119 | + | 105 | Protein_157 | AAA family ATPase | - |
| I6K19_RS25510 (126180) | 126180..126498 | + | 319 | Protein_158 | protein ImpB | - |
| I6K19_RS25515 (126552) | 126552..127249 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| I6K19_RS25520 (127503) | 127503..128525 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| I6K19_RS25525 (128510) | 128510..130075 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| I6K19_RS25530 (130150) | 130150..130566 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | - |
| I6K19_RS25535 (130563) | 130563..130793 | - | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|