MGE detailed information
MGE type: Conjugative plasmid MGE length: 112054 bp
Accession: NZ_CP060975 Location: 1..112054 Organism: Escherichia coli strain EC4 Replicon: plasmid pEC4-2
Accession: NZ_CP060975 Location: 1..112054 Organism: Escherichia coli strain EC4 Replicon: plasmid pEC4-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H9192_RS23540 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| H9192_RS23545 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| H9192_RS23550 (2124) | 2124..2312 | - | 189 | WP_001324033.1 | hypothetical protein | - |
| H9192_RS23555 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| H9192_RS23560 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| H9192_RS23565 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| H9192_RS23570 (6983) | 6983..7680 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| H9192_RS23575 (7730) | 7730..8005 | - | 276 | WP_000421257.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| H9192_RS23580 (8005) | 8005..8289 | - | 285 | WP_001178089.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| H9192_RS23585 (8800) | 8800..9504 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H9192_RS23590 (9570) | 9570..9857 | + | 288 | Protein_10 | IS1380 family transposase ISEcp1 | Transposase |
| H9192_RS23595 (10107) | 10107..10982 | + | 876 | WP_001617865.1 | Beta-lactamase CTX-M-97 | ARG |
| H9192_RS23600 (11017) | 11017..11985 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| H9192_RS23605 (12042) | 12042..12614 | - | 573 | Protein_13 | IS1380 family transposase ISEcp1 | Transposase |
| H9192_RS23610 (12815) | 12815..13846 | + | 1032 | WP_014342102.1 | Methyl-accepting chemotaxis protein McpQ | VF |
| H9192_RS23615 (14035) | 14035..14244 | - | 210 | Protein_15 | dihydropteroate synthase | - |
| H9192_RS23620 (14238) | 14238..14585 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| H9192_RS23625 (14777) | 14777..16036 | - | 1260 | Protein_17 | Inner membrane transport protein YdhC | ARG |
| H9192_RS23630 (16303) | 16303..16857 | - | 555 | WP_032488579.1 | aminoglycoside N-acetyltransferase AAC(6')-Ib3 | - |
| H9192_RS23635 (17037) | 17037..18050 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| H9192_RS23640 (18253) | 18253..18603 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| H9192_RS23645 (18623) | 18623..18688 | + | 66 | Protein_21 | EAL domain-containing protein | - |
| H9192_RS23650 (18806) | 18806..19570 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| H9192_RS23655 (20063) | 20063..20647 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| H9192_RS23660 (20647) | 20647..21885 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| H9192_RS23665 (21882) | 21882..22787 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| H9192_RS23670 (22909) | 22909..23613 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H9192_RS23675 (23678) | 23678..24928 | - | 1251 | Protein_27 | transposase | - |
| H9192_RS23680 (25003) | 25003..25671 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| H9192_RS23685 (25707) | 25707..25943 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| H9192_RS23690 (25940) | 25940..26302 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| H9192_RS23695 (26320) | 26320..28014 | - | 1695 | WP_241461977.1 | mercury(II) reductase | - |
| H9192_RS23700 (28066) | 28066..28488 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| H9192_RS23705 (28524) | 28524..28799 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| H9192_RS23710 (28813) | 28813..29163 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| H9192_RS23715 (29235) | 29235..29669 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| H9192_RS23725 (30722) | 30722..31123 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| H9192_RS23730 (31056) | 31056..31313 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| H9192_RS23735 (31406) | 31406..31714 | - | 309 | WP_226116723.1 | CPBP family intramembrane metalloprotease | - |
| H9192_RS23740 (31656) | 31656..32048 | - | 393 | WP_000616804.1 | histidine phosphatase family protein | - |
| H9192_RS23745 (32987) | 32987..33844 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| H9192_RS23750 (33837) | 33837..34319 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| H9192_RS23755 (34312) | 34312..34359 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| H9192_RS23760 (34350) | 34350..34601 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| H9192_RS23765 (34618) | 34618..34875 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| H9192_RS23770 (35159) | 35159..35308 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (35352) | 35352..35413 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (35352) | 35352..35413 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (35352) | 35352..35413 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (35352) | 35352..35413 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| H9192_RS23775 (35669) | 35669..35743 | - | 75 | Protein_47 | endonuclease | - |
| H9192_RS23780 (35989) | 35989..36201 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| H9192_RS23785 (36337) | 36337..36897 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| H9192_RS23790 (37000) | 37000..37860 | - | 861 | WP_000704514.1 | putative protein YcjY | VF |
| H9192_RS23795 (37919) | 37919..38665 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| H9192_RS23800 (38685) | 38685..38933 | - | 249 | WP_241461978.1 | protein traI | - |
| H9192_RS23805 (38958) | 38958..39662 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| H9192_RS23810 (39714) | 39714..40136 | - | 423 | Protein_54 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| H9192_RS23815 (40262) | 40262..40612 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| H9192_RS23820 (40815) | 40815..41828 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| H9192_RS23825 (41986) | 41986..42459 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| H9192_RS23830 (42533) | 42533..43237 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| H9192_RS23835 (43339) | 43339..43818 | + | 480 | WP_000888203.1 | Rrf2 family transcriptional regulator | - |
| H9192_RS23840 (43888) | 43888..47040 | - | 3153 | WP_000347934.1 | Efflux pump membrane transporter BepE | VF |
| H9192_RS23845 (47064) | 47064..48239 | - | 1176 | WP_002914189.1 | Efflux pump periplasmic linker BepF | VF |
| H9192_RS23850 (48559) | 48559..49263 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| H9192_RS23855 (49315) | 49315..54384 | - | 5070 | Protein_63 | Multifunctional conjugation protein TraI | Relaxase |
| H9192_RS23860 (54466) | 54466..54693 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| H9192_RS23865 (54693) | 54693..55091 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| H9192_RS23870 (55100) | 55100..57253 | - | 2154 | WP_241461980.1 | type IV conjugative transfer system coupling protein TraD | - |
| H9192_RS23875 (57506) | 57506..58237 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| H9192_RS23880 (58269) | 58269..58766 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| H9192_RS23885 (58782) | 58782..61603 | - | 2822 | Protein_69 | conjugal transfer mating-pair stabilization protein TraG | - |
| H9192_RS23890 (61600) | 61600..62973 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| H9192_RS23895 (62973) | 62973..63353 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| H9192_RS23900 (63340) | 63340..63681 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| H9192_RS23905 (63611) | 63611..64156 | - | 546 | WP_241461972.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H9192_RS23910 (64143) | 64143..64427 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H9192_RS23915 (64508) | 64508..64822 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| H9192_RS23920 (64824) | 64824..65171 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| H9192_RS23925 (65187) | 65187..65930 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H9192_RS23930 (65923) | 65923..66180 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| H9192_RS23935 (66207) | 66207..68015 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H9192_RS23940 (68012) | 68012..68650 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H9192_RS23945 (68659) | 68659..69651 | - | 993 | WP_241461974.1 | conjugal transfer pilus assembly protein TraU | - |
| H9192_RS23950 (69648) | 69648..70280 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| H9192_RS23955 (70277) | 70277..70663 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| H9192_RS23960 (70660) | 70660..73287 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| H9192_RS23965 (73447) | 73447..73668 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| H9192_RS23970 (73803) | 73803..74318 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H9192_RS23975 (74315) | 74315..74566 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| H9192_RS23980 (74578) | 74578..74775 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| H9192_RS23985 (74762) | 74762..75352 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| H9192_RS23990 (75342) | 75342..76769 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| H9192_RS23995 (76769) | 76769..77497 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| H9192_RS24000 (77484) | 77484..78050 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| H9192_RS24005 (78072) | 78072..78383 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| H9192_RS24010 (78398) | 78398..78763 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| H9192_RS24015 (78796) | 78796..79197 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| H9192_RS24020 (79290) | 79290..79979 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| H9192_RS24025 (80166) | 80166..80549 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| H9192_RS24030 (80870) | 80870..81472 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| H9192_RS24035 (81769) | 81769..82590 | - | 822 | WP_241461981.1 | DUF932 domain-containing protein | - |
| H9192_RS24040 (82708) | 82708..82995 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| H9192_RS24045 (83020) | 83020..83226 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| H9192_RS24050 (83296) | 83296..83468 | + | 173 | Protein_102 | hypothetical protein | - |
| H9192_RS24055 (83466) | 83466..83696 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| H9192_RS24060 (83916) | 83916..84041 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H9192_RS24065 (83983) | 83983..84132 | - | 150 | Protein_105 | plasmid maintenance protein Mok | - |
| - (84118) | 84118..84342 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (84118) | 84118..84342 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (84118) | 84118..84342 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (84118) | 84118..84342 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| H9192_RS24070 (84154) | 84154..84342 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| H9192_RS24075 (84311) | 84311..85073 | - | 763 | Protein_107 | plasmid SOS inhibition protein A | - |
| H9192_RS24080 (85070) | 85070..85504 | - | 435 | WP_241461975.1 | conjugation system SOS inhibitor PsiB | - |
| H9192_RS24085 (85559) | 85559..85756 | - | 198 | Protein_109 | hypothetical protein | - |
| H9192_RS24090 (85784) | 85784..86017 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| H9192_RS24095 (86085) | 86085..86624 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| H9192_RS24100 (86650) | 86650..86856 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| H9192_RS24105 (86926) | 86926..87006 | + | 81 | Protein_113 | hypothetical protein | - |
| H9192_RS24110 (87189) | 87189..87358 | - | 170 | Protein_114 | hypothetical protein | - |
| H9192_RS24115 (87995) | 87995..88966 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| H9192_RS24120 (88966) | 88966..90132 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| H9192_RS24130 (91200) | 91200..91877 | + | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| H9192_RS24135 (91877) | 91877..92224 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| H9192_RS24140 (92244) | 92244..93815 | + | 1572 | WP_029392005.1 | IS66 family transposase ISCro1 | Transposase |
| H9192_RS24145 (94321) | 94321..96522 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| H9192_RS24150 (96548) | 96548..97881 | - | 1334 | Protein_122 | L-lysine N6-monooxygenase | VF |
| H9192_RS24155 (97878) | 97878..99620 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| H9192_RS24160 (99620) | 99620..100567 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| H9192_RS24165 (100568) | 100568..102292 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| H9192_RS24170 (102428) | 102428..103621 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| H9192_RS24175 (104001) | 104001..104381 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| H9192_RS24180 (104722) | 104722..105135 | - | 414 | Protein_128 | phosphopyruvate hydratase | - |
| H9192_RS24185 (105133) | 105133..105390 | + | 258 | Protein_129 | Tn3 family transposase | - |
| H9192_RS24190 (105624) | 105624..106481 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| H9192_RS24195 (106478) | 106478..107335 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| H9192_RS24200 (107332) | 107332..108159 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| H9192_RS24205 (108159) | 108159..109073 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| H9192_RS24210 (109429) | 109429..110126 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| H9192_RS24215 (110306) | 110306..110819 | - | 514 | Protein_135 | DUF4113 domain-containing protein | - |
| H9192_RS24220 (110880) | 110880..110984 | - | 105 | Protein_136 | AAA family ATPase | - |
| H9192_RS24225 (110986) | 110986..111309 | - | 324 | Protein_137 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|