MGE detailed information
MGE type: Conjugative plasmid MGE length: 147459 bp
Accession: NZ_CP060868 Location: 1..147459 Organism: Escherichia coli strain EC29 Replicon: plasmid pEC29-NDM-5
Accession: NZ_CP060868 Location: 1..147459 Organism: Escherichia coli strain EC29 Replicon: plasmid pEC29-NDM-5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
H9211_RS23640 (1) | 1..858 | + | 858 | WP_029702152.1 | incFII family plasmid replication initiator RepA | - |
H9211_RS23645 (1559) | 1559..1699 | + | 141 | WP_001333237.1 | hypothetical protein | - |
H9211_RS23650 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
H9211_RS23655 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
H9211_RS23660 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
H9211_RS23665 (3271) | 3271..6168 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
H9211_RS23670 (6263) | 6263..6868 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
H9211_RS23675 (6892) | 6892..7641 | - | 750 | Protein_7 | Tn3 family transposase TnpA_TnAs1 | Transposase |
H9211_RS23680 (7645) | 7645..8037 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
H9211_RS23685 (8175) | 8175..9059 | + | 885 | WP_000058717.1 | EamA family transporter | - |
H9211_RS23690 (9091) | 9091..10290 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
H9211_RS23695 (10396) | 10396..11046 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
H9211_RS23700 (11078) | 11078..11320 | - | 243 | WP_032140899.1 | hypothetical protein | - |
H9211_RS23705 (11362) | 11362..12876 | - | 1515 | Protein_13 | Tn3 family transposase TnpA_TnAs1 | Transposase |
H9211_RS23710 (12942) | 12942..13646 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
H9211_RS23715 (13790) | 13790..14344 | + | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
H9211_RS23720 (14475) | 14475..15305 | + | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
H9211_RS23725 (15443) | 15443..15883 | + | 441 | Protein_17 | CatB-related O-acetyltransferase | - |
H9211_RS23730 (15937) | 15937..16641 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
H9211_RS23735 (16707) | 16707..16994 | + | 288 | Protein_19 | IS1380 family transposase ISEcp1 | Transposase |
H9211_RS23740 (17250) | 17250..18125 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
H9211_RS23745 (18172) | 18172..18465 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
H9211_RS23750 (18530) | 18530..20749 | + | 2220 | Protein_22 | Tn3 family transposase TnpA_Tn3 | Transposase |
H9211_RS23755 (20826) | 20826..21530 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
H9211_RS23760 (21585) | 21585..22451 | - | 867 | Protein_24 | IS91 family transposase ISAzo26 | Transposase |
H9211_RS23765 (22596) | 22596..23093 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
H9211_RS23770 (23205) | 23205..23495 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
H9211_RS23775 (23501) | 23501..24339 | + | 839 | Protein_27 | Streptomycin 3''-adenylyltransferase | ARG |
H9211_RS23780 (24456) | 24456..24803 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
H9211_RS23785 (24797) | 24797..25636 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
H9211_RS23790 (26041) | 26041..27582 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
H9211_RS23795 (27895) | 27895..28269 | + | 375 | Protein_31 | protein-disulfide reductase DsbD family protein | - |
H9211_RS23800 (28369) | 28369..28926 | + | 558 | Protein_32 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
H9211_RS23805 (28937) | 28937..29575 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
H9211_RS23810 (29580) | 29580..29945 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
H9211_RS23815 (29949) | 29949..30761 | - | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
H9211_RS23820 (30862) | 30862..31155 | - | 294 | Protein_36 | IS30 family transposase ISAba125 | Transposase |
H9211_RS23825 (31320) | 31320..32024 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
H9211_RS23830 (32079) | 32079..32945 | - | 867 | Protein_38 | IS91 family transposase ISAzo26 | Transposase |
H9211_RS23835 (33090) | 33090..33587 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
H9211_RS23840 (33699) | 33699..33989 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
H9211_RS23845 (33995) | 33995..34833 | + | 839 | Protein_41 | Streptomycin 3''-adenylyltransferase | ARG |
H9211_RS23850 (34950) | 34950..35297 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
H9211_RS23855 (35291) | 35291..36130 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
H9211_RS23860 (36535) | 36535..38076 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
H9211_RS23865 (38389) | 38389..38763 | + | 375 | Protein_45 | protein-disulfide reductase DsbD family protein | - |
H9211_RS23870 (38863) | 38863..39420 | + | 558 | Protein_46 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
H9211_RS23875 (39431) | 39431..40069 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
H9211_RS23880 (40074) | 40074..40439 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
H9211_RS23885 (40443) | 40443..41255 | - | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
H9211_RS23890 (41356) | 41356..41649 | - | 294 | Protein_50 | IS30 family transposase ISAba125 | Transposase |
H9211_RS23895 (41814) | 41814..42518 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
H9211_RS23900 (42712) | 42712..43062 | - | 351 | Protein_52 | 60 kDa chaperonin | VF |
H9211_RS23905 (43125) | 43125..43673 | + | 549 | WP_014342204.1 | cation:proton antiporter | - |
H9211_RS23910 (43754) | 43754..44509 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
H9211_RS23915 (44679) | 44679..45539 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
H9211_RS23920 (45722) | 45722..46279 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
H9211_RS23925 (46581) | 46581..47345 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
H9211_RS23930 (47838) | 47838..48422 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
H9211_RS23935 (48422) | 48422..49660 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
H9211_RS23940 (49657) | 49657..50571 | - | 915 | WP_023063803.1 | hypothetical protein | ARG |
H9211_RS23945 (50693) | 50693..51397 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
H9211_RS23950 (51458) | 51458..53869 | + | 2412 | Protein_62 | Tn3 family transposase TnpA_ISSba14 | Transposase |
H9211_RS23955 (53903) | 53903..54007 | + | 105 | Protein_63 | IS5/IS1182 family transposase | - |
H9211_RS23960 (54157) | 54157..54789 | - | 633 | Protein_64 | histidine-type phosphatase | - |
H9211_RS23965 (54911) | 54911..55396 | - | 486 | WP_000874189.1 | hypothetical protein | - |
H9211_RS23970 (55421) | 55421..55906 | - | 486 | WP_001267176.1 | TlpA disulfide reductase family protein | - |
H9211_RS23975 (55893) | 55893..56588 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
H9211_RS23980 (56593) | 56593..57723 | - | 1131 | WP_000729219.1 | ABC transporter permease | - |
H9211_RS23985 (57713) | 57713..58996 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
H9211_RS23990 (58999) | 58999..60378 | - | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
H9211_RS23995 (60482) | 60482..61009 | - | 528 | WP_000178050.1 | iron transporter | - |
H9211_RS24000 (61050) | 61050..62936 | - | 1887 | WP_000118029.1 | FTR1 family protein | - |
H9211_RS24005 (63283) | 63283..64044 | - | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
H9211_RS24010 (64281) | 64281..64787 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
H9211_RS24015 (64777) | 64777..64947 | - | 171 | Protein_75 | DsbA family protein | - |
H9211_RS24020 (65085) | 65085..65198 | - | 114 | Protein_76 | IS6 family transposase | - |
H9211_RS24025 (65398) | 65398..66095 | + | 698 | WP_223350503.1 | IS1 family transposase IS1X2 | Transposase |
H9211_RS24030 (66245) | 66245..66931 | + | 687 | Protein_78 | IS1 family transposase IS1S | Transposase |
H9211_RS24035 (67185) | 67185..68207 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
H9211_RS24040 (68192) | 68192..69757 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
H9211_RS24045 (69832) | 69832..70248 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
H9211_RS24050 (70245) | 70245..70475 | - | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
H9211_RS24055 (71035) | 71035..71253 | + | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
H9211_RS24060 (71255) | 71255..71560 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
H9211_RS24065 (71561) | 71561..72367 | + | 807 | WP_000016970.1 | site-specific integrase | - |
H9211_RS24070 (73089) | 73089..73844 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
H9211_RS24075 (74432) | 74432..75598 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
H9211_RS24080 (75598) | 75598..76569 | + | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
H9211_RS24085 (77307) | 77307..78209 | + | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
H9211_RS24090 (78206) | 78206..78517 | + | 312 | WP_012615291.1 | hypothetical protein | - |
H9211_RS24095 (78594) | 78594..79277 | + | 684 | WP_032181561.1 | DNA methylase | - |
H9211_RS24100 (79278) | 79278..79499 | + | 222 | WP_001104873.1 | hypothetical protein | - |
H9211_RS24105 (79429) | 79429..79947 | + | 519 | WP_223349485.1 | DUF1380 family protein | - |
H9211_RS24110 (79992) | 79992..80762 | + | 771 | WP_001006251.1 | hypothetical protein | - |
H9211_RS24115 (81176) | 81176..81601 | + | 426 | WP_001546490.1 | antirestriction protein | - |
H9211_RS24120 (81648) | 81648..82070 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
H9211_RS24125 (82067) | 82067..82258 | + | 192 | WP_001027495.1 | hypothetical protein | - |
H9211_RS24130 (82571) | 82571..84238 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
H9211_RS24135 (84967) | 84967..85121 | - | 155 | Protein_99 | hypothetical protein | - |
H9211_RS24140 (85638) | 85638..85868 | + | 231 | WP_000218642.1 | hypothetical protein | - |
H9211_RS24145 (85920) | 85920..87281 | + | 1362 | WP_039023242.1 | DUF3560 domain-containing protein | - |
H9211_RS24150 (87329) | 87329..87892 | + | 564 | WP_029702196.1 | class I SAM-dependent methyltransferase | - |
H9211_RS24155 (87978) | 87978..88160 | - | 183 | Protein_103 | pilus protein | - |
H9211_RS24160 (88273) | 88273..89940 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
H9211_RS24165 (91602) | 91602..92171 | - | 570 | WP_089634947.1 | hypothetical protein | - |
H9211_RS24175 (93475) | 93475..94233 | + | 759 | Protein_107 | site-specific integrase | - |
H9211_RS24180 (94391) | 94391..95401 | + | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
H9211_RS24185 (95497) | 95497..97623 | + | 2127 | WP_000253905.1 | alpha-galactosidase | - |
H9211_RS24190 (97686) | 97686..98963 | + | 1278 | WP_001083369.1 | MFS transporter | - |
H9211_RS24195 (98963) | 98963..100393 | + | 1431 | WP_000813680.1 | glycoside hydrolase family 32 protein | - |
H9211_RS24200 (100588) | 100588..101982 | + | 1395 | WP_001037799.1 | carbohydrate porin | - |
H9211_RS24205 (102228) | 102228..102332 | - | 105 | Protein_113 | thiosulfate reductase cytochrome B subunit | - |
H9211_RS24210 (102389) | 102389..103086 | + | 698 | WP_241418171.1 | IS1 family transposase IS1S | Transposase |
H9211_RS24215 (103213) | 103213..103725 | + | 513 | WP_223350513.1 | potassium channel family protein | - |
H9211_RS24220 (103810) | 103810..104061 | + | 252 | Protein_116 | iron-containing alcohol dehydrogenase | - |
H9211_RS24225 (104350) | 104350..104667 | - | 318 | Protein_117 | IS110 family transposase IS1618 | Transposase |
H9211_RS24230 (104822) | 104822..104927 | + | 106 | Protein_118 | plasmid SOS inhibition protein A | - |
- (104896) | 104896..105094 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
- (104896) | 104896..105094 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
- (104896) | 104896..105094 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
- (104896) | 104896..105094 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
H9211_RS24235 (105101) | 105101..105250 | + | 150 | Protein_119 | DUF5431 family protein | - |
H9211_RS24240 (105192) | 105192..105317 | + | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
H9211_RS24245 (105618) | 105618..105915 | - | 298 | Protein_121 | hypothetical protein | - |
H9211_RS24250 (105985) | 105985..106191 | + | 207 | WP_000275854.1 | hypothetical protein | - |
H9211_RS24255 (106216) | 106216..106503 | + | 288 | WP_000107242.1 | hypothetical protein | - |
H9211_RS24260 (106622) | 106622..107443 | + | 822 | WP_001234465.1 | DUF932 domain-containing protein | - |
H9211_RS24265 (107739) | 107739..108311 | - | 573 | WP_000949660.1 | hypothetical protein | VF |
H9211_RS24270 (108681) | 108681..109064 | + | 384 | WP_001063020.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
H9211_RS24275 (109255) | 109255..109902 | + | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
H9211_RS24280 (110038) | 110038..110253 | + | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
H9211_RS24285 (110296) | 110296..110661 | + | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
H9211_RS24290 (110676) | 110676..110987 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
H9211_RS24295 (111009) | 111009..111575 | + | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
H9211_RS24300 (111562) | 111562..112290 | + | 729 | WP_001230813.1 | type-F conjugative transfer system secretin TraK | - |
H9211_RS24305 (112290) | 112290..113717 | + | 1428 | WP_001553836.1 | F-type conjugal transfer pilus assembly protein TraB | - |
H9211_RS24310 (113707) | 113707..114297 | + | 591 | WP_000002787.1 | conjugal transfer pilus-stabilizing protein TraP | - |
H9211_RS24315 (114284) | 114284..114604 | + | 321 | Protein_135 | conjugal transfer protein TrbD | - |
H9211_RS24320 (114597) | 114597..114848 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
H9211_RS24325 (114845) | 114845..115360 | + | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
H9211_RS24330 (115495) | 115495..115716 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
H9211_RS24335 (115876) | 115876..118503 | + | 2628 | WP_039021964.1 | type IV secretion system protein TraC | - |
H9211_RS24340 (118500) | 118500..118886 | + | 387 | WP_000214092.1 | type-F conjugative transfer system protein TrbI | - |
H9211_RS24345 (118883) | 118883..119515 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
H9211_RS24350 (119512) | 119512..120504 | + | 993 | WP_001553833.1 | conjugal transfer pilus assembly protein TraU | - |
H9211_RS24355 (120513) | 120513..121151 | + | 639 | WP_001553832.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
H9211_RS24360 (121148) | 121148..122956 | + | 1809 | WP_039023153.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
H9211_RS24365 (122983) | 122983..123240 | + | 258 | WP_039023152.1 | conjugal transfer protein TrbE | - |
H9211_RS24370 (123233) | 123233..123976 | + | 744 | WP_143212015.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
H9211_RS24375 (123992) | 123992..124339 | + | 348 | WP_001287894.1 | conjugal transfer protein TrbA | - |
H9211_RS24380 (124458) | 124458..124742 | + | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
H9211_RS24385 (124729) | 124729..125274 | + | 546 | WP_016236310.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
H9211_RS24390 (125204) | 125204..125566 | + | 363 | WP_071550055.1 | P-type conjugative transfer protein TrbJ | - |
H9211_RS24395 (125566) | 125566..126939 | + | 1374 | WP_039023150.1 | conjugal transfer pilus assembly protein TraH | - |
H9211_RS24400 (126936) | 126936..129755 | + | 2820 | WP_039023149.1 | conjugal transfer mating-pair stabilization protein TraG | - |
H9211_RS24405 (129774) | 129774..130271 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
H9211_RS24410 (130303) | 130303..131034 | + | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
H9211_RS24415 (131287) | 131287..133530 | + | 2244 | WP_094907434.1 | type IV conjugative transfer system coupling protein TraD | - |
H9211_RS24420 (133539) | 133539..133937 | - | 399 | WP_039023147.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
H9211_RS24425 (133937) | 133937..134164 | - | 228 | WP_039023146.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
H9211_RS24430 (134246) | 134246..139516 | + | 5271 | WP_039023145.1 | Multifunctional conjugation protein TraI | Relaxase |
H9211_RS24435 (139792) | 139792..141333 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
H9211_RS24440 (141348) | 141348..142094 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
H9211_RS24445 (142122) | 142122..142868 | + | 747 | WP_052273601.1 | conjugal transfer pilus acetylase TraX | - |
H9211_RS24450 (142923) | 142923..143483 | + | 561 | WP_001567328.1 | fertility inhibition protein FinO | - |
H9211_RS24455 (143614) | 143614..143823 | + | 210 | WP_039023209.1 | hypothetical protein | - |
H9211_RS24460 (144235) | 144235..144861 | + | 627 | WP_029702149.1 | NYN domain-containing protein | - |
H9211_RS24465 (145013) | 145013..145582 | + | 570 | WP_029702150.1 | DUF2726 domain-containing protein | - |
H9211_RS24470 (145795) | 145795..146223 | + | 429 | WP_029702151.1 | hypothetical protein | - |
- (146362) | 146362..146423 | - | 62 | NuclAT_1 | - | - |
- (146362) | 146362..146423 | - | 62 | NuclAT_1 | - | - |
- (146362) | 146362..146423 | - | 62 | NuclAT_1 | - | - |
- (146362) | 146362..146423 | - | 62 | NuclAT_1 | - | - |
H9211_RS24475 (146467) | 146467..146616 | + | 150 | WP_001367749.1 | Hok/Gef family protein | - |
H9211_RS24480 (146900) | 146900..147157 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
H9211_RS24485 (147262) | 147262..147447 | + | 186 | WP_077818652.1 | protein CopA/IncA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
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