NZ_CP0608681..147459

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 147459 bp
Accession: NZ_CP060868        Location: 1..147459         Organism: Escherichia coli strain EC29       Replicon: plasmid pEC29-NDM-5


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9211_RS23640 (1) 1..858 + 858 WP_029702152.1 incFII family plasmid replication initiator RepA -
H9211_RS23645 (1559) 1559..1699 + 141 WP_001333237.1 hypothetical protein -
H9211_RS23650 (1797) 1797..2450 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
H9211_RS23655 (2543) 2543..2800 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
H9211_RS23660 (2733) 2733..3134 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
H9211_RS23665 (3271) 3271..6168 - 2898 WP_001553819.1 Tn3 family transposase TnpA_Tn5403 Transposase
H9211_RS23670 (6263) 6263..6868 + 606 WP_000509965.1 Tn3 family transposase TnpR_Tn5403 Transposase
H9211_RS23675 (6892) 6892..7641 - 750 Protein_7 Tn3 family transposase TnpA_TnAs1 Transposase
H9211_RS23680 (7645) 7645..8037 + 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
H9211_RS23685 (8175) 8175..9059 + 885 WP_000058717.1 EamA family transporter -
H9211_RS23690 (9091) 9091..10290 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
H9211_RS23695 (10396) 10396..11046 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
H9211_RS23700 (11078) 11078..11320 - 243 WP_032140899.1 hypothetical protein -
H9211_RS23705 (11362) 11362..12876 - 1515 Protein_13 Tn3 family transposase TnpA_TnAs1 Transposase
H9211_RS23710 (12942) 12942..13646 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
H9211_RS23715 (13790) 13790..14344 + 555 WP_063840321.1 Aminoglycoside N(6')-acetyltransferase type 1 ARG
H9211_RS23720 (14475) 14475..15305 + 831 WP_001334766.1 Beta-lactamase OXA-1 ARG
H9211_RS23725 (15443) 15443..15883 + 441 Protein_17 CatB-related O-acetyltransferase -
H9211_RS23730 (15937) 15937..16641 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
H9211_RS23735 (16707) 16707..16994 + 288 Protein_19 IS1380 family transposase ISEcp1 Transposase
H9211_RS23740 (17250) 17250..18125 + 876 WP_000239590.1 Beta-lactamase CTX-M-1 ARG
H9211_RS23745 (18172) 18172..18465 - 294 WP_116961751.1 WbuC family cupin fold metalloprotein -
H9211_RS23750 (18530) 18530..20749 + 2220 Protein_22 Tn3 family transposase TnpA_Tn3 Transposase
H9211_RS23755 (20826) 20826..21530 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
H9211_RS23760 (21585) 21585..22451 - 867 Protein_24 IS91 family transposase ISAzo26 Transposase
H9211_RS23765 (22596) 22596..23093 + 498 WP_001083725.1 Dihydrofolate reductase ARG
H9211_RS23770 (23205) 23205..23495 + 291 WP_001336345.1 DUF1010 domain-containing protein -
H9211_RS23775 (23501) 23501..24339 + 839 Protein_27 Streptomycin 3''-adenylyltransferase ARG
H9211_RS23780 (24456) 24456..24803 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
H9211_RS23785 (24797) 24797..25636 + 840 WP_000259031.1 Dihydropteroate synthase ARG
H9211_RS23790 (26041) 26041..27582 + 1542 WP_000050481.1 IS91 family transposase ISVsa3 Transposase
H9211_RS23795 (27895) 27895..28269 + 375 Protein_31 protein-disulfide reductase DsbD family protein -
H9211_RS23800 (28369) 28369..28926 + 558 Protein_32 twin-arginine translocation (TAT) pathway signal sequence domain protein -
H9211_RS23805 (28937) 28937..29575 - 639 WP_004201168.1 phosphoribosylanthranilate isomerase -
H9211_RS23810 (29580) 29580..29945 - 366 WP_004201167.1 bleomycin binding protein Ble-MBL -
H9211_RS23815 (29949) 29949..30761 - 813 WP_023408309.1 Metallo-beta-lactamase type 2 ARG
H9211_RS23820 (30862) 30862..31155 - 294 Protein_36 IS30 family transposase ISAba125 Transposase
H9211_RS23825 (31320) 31320..32024 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
H9211_RS23830 (32079) 32079..32945 - 867 Protein_38 IS91 family transposase ISAzo26 Transposase
H9211_RS23835 (33090) 33090..33587 + 498 WP_001083725.1 Dihydrofolate reductase ARG
H9211_RS23840 (33699) 33699..33989 + 291 WP_001336345.1 DUF1010 domain-containing protein -
H9211_RS23845 (33995) 33995..34833 + 839 Protein_41 Streptomycin 3''-adenylyltransferase ARG
H9211_RS23850 (34950) 34950..35297 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
H9211_RS23855 (35291) 35291..36130 + 840 WP_000259031.1 Dihydropteroate synthase ARG
H9211_RS23860 (36535) 36535..38076 + 1542 WP_000050481.1 IS91 family transposase ISVsa3 Transposase
H9211_RS23865 (38389) 38389..38763 + 375 Protein_45 protein-disulfide reductase DsbD family protein -
H9211_RS23870 (38863) 38863..39420 + 558 Protein_46 twin-arginine translocation (TAT) pathway signal sequence domain protein -
H9211_RS23875 (39431) 39431..40069 - 639 WP_004201168.1 phosphoribosylanthranilate isomerase -
H9211_RS23880 (40074) 40074..40439 - 366 WP_004201167.1 bleomycin binding protein Ble-MBL -
H9211_RS23885 (40443) 40443..41255 - 813 WP_023408309.1 Metallo-beta-lactamase type 2 ARG
H9211_RS23890 (41356) 41356..41649 - 294 Protein_50 IS30 family transposase ISAba125 Transposase
H9211_RS23895 (41814) 41814..42518 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
H9211_RS23900 (42712) 42712..43062 - 351 Protein_52 60 kDa chaperonin VF
H9211_RS23905 (43125) 43125..43673 + 549 WP_014342204.1 cation:proton antiporter -
H9211_RS23910 (43754) 43754..44509 - 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
H9211_RS23915 (44679) 44679..45539 - 861 WP_000027057.1 Beta-lactamase TEM ARG
H9211_RS23920 (45722) 45722..46279 - 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
H9211_RS23925 (46581) 46581..47345 + 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
H9211_RS23930 (47838) 47838..48422 - 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
H9211_RS23935 (48422) 48422..49660 - 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
H9211_RS23940 (49657) 49657..50571 - 915 WP_023063803.1 hypothetical protein ARG
H9211_RS23945 (50693) 50693..51397 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
H9211_RS23950 (51458) 51458..53869 + 2412 Protein_62 Tn3 family transposase TnpA_ISSba14 Transposase
H9211_RS23955 (53903) 53903..54007 + 105 Protein_63 IS5/IS1182 family transposase -
H9211_RS23960 (54157) 54157..54789 - 633 Protein_64 histidine-type phosphatase -
H9211_RS23965 (54911) 54911..55396 - 486 WP_000874189.1 hypothetical protein -
H9211_RS23970 (55421) 55421..55906 - 486 WP_001267176.1 TlpA disulfide reductase family protein -
H9211_RS23975 (55893) 55893..56588 - 696 WP_000117262.1 Lipoprotein-releasing system ATP-binding protein LolD VF
H9211_RS23980 (56593) 56593..57723 - 1131 WP_000729219.1 ABC transporter permease -
H9211_RS23985 (57713) 57713..58996 - 1284 WP_000964653.1 ABC transporter permease -
H9211_RS23990 (58999) 58999..60378 - 1380 WP_000119836.1 Fe-S-containing protein -
H9211_RS23995 (60482) 60482..61009 - 528 WP_000178050.1 iron transporter -
H9211_RS24000 (61050) 61050..62936 - 1887 WP_000118029.1 FTR1 family protein -
H9211_RS24005 (63283) 63283..64044 - 762 WP_001225378.1 Na(+)-translocating NADH-quinone reductase subunit C -
H9211_RS24010 (64281) 64281..64787 - 507 WP_000949452.1 protein disulfide oxidoreductase -
H9211_RS24015 (64777) 64777..64947 - 171 Protein_75 DsbA family protein -
H9211_RS24020 (65085) 65085..65198 - 114 Protein_76 IS6 family transposase -
H9211_RS24025 (65398) 65398..66095 + 698 WP_223350503.1 IS1 family transposase IS1X2 Transposase
H9211_RS24030 (66245) 66245..66931 + 687 Protein_78 IS1 family transposase IS1S Transposase
H9211_RS24035 (67185) 67185..68207 - 1023 WP_000361402.1 helicase UvrD -
H9211_RS24040 (68192) 68192..69757 - 1566 WP_001128474.1 AAA family ATPase -
H9211_RS24045 (69832) 69832..70248 - 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
H9211_RS24050 (70245) 70245..70475 - 231 WP_001261286.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
H9211_RS24055 (71035) 71035..71253 + 219 WP_000813630.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
H9211_RS24060 (71255) 71255..71560 + 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
H9211_RS24065 (71561) 71561..72367 + 807 WP_000016970.1 site-specific integrase -
H9211_RS24070 (73089) 73089..73844 + 756 WP_000852146.1 replication initiation protein RepE -
H9211_RS24075 (74432) 74432..75598 + 1167 WP_000772446.1 Sporulation initiation inhibitor protein Soj VF
H9211_RS24080 (75598) 75598..76569 + 972 WP_000817031.1 ParB/RepB/Spo0J family plasmid partition protein -
H9211_RS24085 (77307) 77307..78209 + 903 WP_064766247.1 DUF1281 domain-containing protein -
H9211_RS24090 (78206) 78206..78517 + 312 WP_012615291.1 hypothetical protein -
H9211_RS24095 (78594) 78594..79277 + 684 WP_032181561.1 DNA methylase -
H9211_RS24100 (79278) 79278..79499 + 222 WP_001104873.1 hypothetical protein -
H9211_RS24105 (79429) 79429..79947 + 519 WP_223349485.1 DUF1380 family protein -
H9211_RS24110 (79992) 79992..80762 + 771 WP_001006251.1 hypothetical protein -
H9211_RS24115 (81176) 81176..81601 + 426 WP_001546490.1 antirestriction protein -
H9211_RS24120 (81648) 81648..82070 + 423 WP_000271685.1 DUF1380 family protein -
H9211_RS24125 (82067) 82067..82258 + 192 WP_001027495.1 hypothetical protein -
H9211_RS24130 (82571) 82571..84238 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
H9211_RS24135 (84967) 84967..85121 - 155 Protein_99 hypothetical protein -
H9211_RS24140 (85638) 85638..85868 + 231 WP_000218642.1 hypothetical protein -
H9211_RS24145 (85920) 85920..87281 + 1362 WP_039023242.1 DUF3560 domain-containing protein -
H9211_RS24150 (87329) 87329..87892 + 564 WP_029702196.1 class I SAM-dependent methyltransferase -
H9211_RS24155 (87978) 87978..88160 - 183 Protein_103 pilus protein -
H9211_RS24160 (88273) 88273..89940 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
H9211_RS24165 (91602) 91602..92171 - 570 WP_089634947.1 hypothetical protein -
H9211_RS24175 (93475) 93475..94233 + 759 Protein_107 site-specific integrase -
H9211_RS24180 (94391) 94391..95401 + 1011 WP_000053332.1 substrate-binding domain-containing protein -
H9211_RS24185 (95497) 95497..97623 + 2127 WP_000253905.1 alpha-galactosidase -
H9211_RS24190 (97686) 97686..98963 + 1278 WP_001083369.1 MFS transporter -
H9211_RS24195 (98963) 98963..100393 + 1431 WP_000813680.1 glycoside hydrolase family 32 protein -
H9211_RS24200 (100588) 100588..101982 + 1395 WP_001037799.1 carbohydrate porin -
H9211_RS24205 (102228) 102228..102332 - 105 Protein_113 thiosulfate reductase cytochrome B subunit -
H9211_RS24210 (102389) 102389..103086 + 698 WP_241418171.1 IS1 family transposase IS1S Transposase
H9211_RS24215 (103213) 103213..103725 + 513 WP_223350513.1 potassium channel family protein -
H9211_RS24220 (103810) 103810..104061 + 252 Protein_116 iron-containing alcohol dehydrogenase -
H9211_RS24225 (104350) 104350..104667 - 318 Protein_117 IS110 family transposase IS1618 Transposase
H9211_RS24230 (104822) 104822..104927 + 106 Protein_118 plasmid SOS inhibition protein A -
- (104896) 104896..105094 + 199 NuclAT_0 - Antitoxin Detail
- (104896) 104896..105094 + 199 NuclAT_0 - Antitoxin Detail
- (104896) 104896..105094 + 199 NuclAT_0 - Antitoxin Detail
- (104896) 104896..105094 + 199 NuclAT_0 - Antitoxin Detail
H9211_RS24235 (105101) 105101..105250 + 150 Protein_119 DUF5431 family protein -
H9211_RS24240 (105192) 105192..105317 + 126 WP_096937776.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
H9211_RS24245 (105618) 105618..105915 - 298 Protein_121 hypothetical protein -
H9211_RS24250 (105985) 105985..106191 + 207 WP_000275854.1 hypothetical protein -
H9211_RS24255 (106216) 106216..106503 + 288 WP_000107242.1 hypothetical protein -
H9211_RS24260 (106622) 106622..107443 + 822 WP_001234465.1 DUF932 domain-containing protein -
H9211_RS24265 (107739) 107739..108311 - 573 WP_000949660.1 hypothetical protein VF
H9211_RS24270 (108681) 108681..109064 + 384 WP_001063020.1 conjugal transfer relaxosome DNA-binding protein TraM -
H9211_RS24275 (109255) 109255..109902 + 648 WP_000332520.1 conjugal transfer transcriptional regulator TraJ -
H9211_RS24280 (110038) 110038..110253 + 216 WP_001352842.1 conjugal transfer relaxosome protein TraY -
H9211_RS24285 (110296) 110296..110661 + 366 WP_000340282.1 type IV conjugative transfer system pilin TraA -
H9211_RS24290 (110676) 110676..110987 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
H9211_RS24295 (111009) 111009..111575 + 567 WP_000399790.1 type IV conjugative transfer system protein TraE -
H9211_RS24300 (111562) 111562..112290 + 729 WP_001230813.1 type-F conjugative transfer system secretin TraK -
H9211_RS24305 (112290) 112290..113717 + 1428 WP_001553836.1 F-type conjugal transfer pilus assembly protein TraB -
H9211_RS24310 (113707) 113707..114297 + 591 WP_000002787.1 conjugal transfer pilus-stabilizing protein TraP -
H9211_RS24315 (114284) 114284..114604 + 321 Protein_135 conjugal transfer protein TrbD -
H9211_RS24320 (114597) 114597..114848 + 252 WP_001038342.1 conjugal transfer protein TrbG -
H9211_RS24325 (114845) 114845..115360 + 516 WP_000809832.1 type IV conjugative transfer system lipoprotein TraV -
H9211_RS24330 (115495) 115495..115716 + 222 WP_001278692.1 conjugal transfer protein TraR -
H9211_RS24335 (115876) 115876..118503 + 2628 WP_039021964.1 type IV secretion system protein TraC -
H9211_RS24340 (118500) 118500..118886 + 387 WP_000214092.1 type-F conjugative transfer system protein TrbI -
H9211_RS24345 (118883) 118883..119515 + 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
H9211_RS24350 (119512) 119512..120504 + 993 WP_001553833.1 conjugal transfer pilus assembly protein TraU -
H9211_RS24355 (120513) 120513..121151 + 639 WP_001553832.1 type-F conjugative transfer system pilin assembly protein TrbC -
H9211_RS24360 (121148) 121148..122956 + 1809 WP_039023153.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
H9211_RS24365 (122983) 122983..123240 + 258 WP_039023152.1 conjugal transfer protein TrbE -
H9211_RS24370 (123233) 123233..123976 + 744 WP_143212015.1 type-F conjugative transfer system pilin assembly protein TraF -
H9211_RS24375 (123992) 123992..124339 + 348 WP_001287894.1 conjugal transfer protein TrbA -
H9211_RS24380 (124458) 124458..124742 + 285 WP_000624110.1 type-F conjugative transfer system pilin chaperone TraQ -
H9211_RS24385 (124729) 124729..125274 + 546 WP_016236310.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
H9211_RS24390 (125204) 125204..125566 + 363 WP_071550055.1 P-type conjugative transfer protein TrbJ -
H9211_RS24395 (125566) 125566..126939 + 1374 WP_039023150.1 conjugal transfer pilus assembly protein TraH -
H9211_RS24400 (126936) 126936..129755 + 2820 WP_039023149.1 conjugal transfer mating-pair stabilization protein TraG -
H9211_RS24405 (129774) 129774..130271 + 498 WP_000605862.1 entry exclusion protein -
H9211_RS24410 (130303) 130303..131034 + 732 WP_000850422.1 conjugal transfer complement resistance protein TraT -
H9211_RS24415 (131287) 131287..133530 + 2244 WP_094907434.1 type IV conjugative transfer system coupling protein TraD -
H9211_RS24420 (133539) 133539..133937 - 399 WP_039023147.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
H9211_RS24425 (133937) 133937..134164 - 228 WP_039023146.1 toxin-antitoxin system antitoxin VapB Antitoxin Detail
H9211_RS24430 (134246) 134246..139516 + 5271 WP_039023145.1 Multifunctional conjugation protein TraI Relaxase
H9211_RS24435 (139792) 139792..141333 + 1542 WP_002431311.1 IS21 family transposase ISEc12 Transposase
H9211_RS24440 (141348) 141348..142094 + 747 WP_001016257.1 IS21 family transposase ISEc12 Transposase
H9211_RS24445 (142122) 142122..142868 + 747 WP_052273601.1 conjugal transfer pilus acetylase TraX -
H9211_RS24450 (142923) 142923..143483 + 561 WP_001567328.1 fertility inhibition protein FinO -
H9211_RS24455 (143614) 143614..143823 + 210 WP_039023209.1 hypothetical protein -
H9211_RS24460 (144235) 144235..144861 + 627 WP_029702149.1 NYN domain-containing protein -
H9211_RS24465 (145013) 145013..145582 + 570 WP_029702150.1 DUF2726 domain-containing protein -
H9211_RS24470 (145795) 145795..146223 + 429 WP_029702151.1 hypothetical protein -
- (146362) 146362..146423 - 62 NuclAT_1 - -
- (146362) 146362..146423 - 62 NuclAT_1 - -
- (146362) 146362..146423 - 62 NuclAT_1 - -
- (146362) 146362..146423 - 62 NuclAT_1 - -
H9211_RS24475 (146467) 146467..146616 + 150 WP_001367749.1 Hok/Gef family protein -
H9211_RS24480 (146900) 146900..147157 + 258 WP_000083833.1 replication regulatory protein RepA -
H9211_RS24485 (147262) 147262..147447 + 186 WP_077818652.1 protein CopA/IncA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance