MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 169990 bp
Accession: NZ_CP058549 Location: 1..169990 Organism: Klebsiella pneumoniae strain S165-1 Replicon: plasmid pS165-1.1
Accession: NZ_CP058549 Location: 1..169990 Organism: Klebsiella pneumoniae strain S165-1 Replicon: plasmid pS165-1.1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HXT63_RS26360 | 244..643 | - | 400 | Protein_1 | cysteine hydrolase | - |
| HXT63_RS26365 | 638..2386 | + | 1749 | Protein_2 | Tn3-like element TnAs1 family transposase | - |
| HXT63_RS26370 | 2910..3188 | - | 279 | WP_004118062.1 | DUF1778 domain-containing protein | - |
| HXT63_RS26375 | 3282..3494 | - | 213 | WP_004181742.1 | hypothetical protein | - |
| HXT63_RS26380 | 4460..4884 | - | 425 | Protein_5 | hypothetical protein | - |
| HXT63_RS26385 | 6113..6997 | + | 885 | WP_004186900.1 | hypothetical protein | - |
| HXT63_RS26390 | 7119..7598 | - | 480 | WP_157986872.1 | hypothetical protein | - |
| HXT63_RS26395 | 7620..8057 | + | 438 | WP_237086700.1 | hypothetical protein | - |
| HXT63_RS26400 | 8403..9371 | + | 969 | WP_074187998.1 | IS5-like element IS903B family transposase | - |
| HXT63_RS26405 | 9524..10060 | + | 537 | WP_080876707.1 | plasmid transfer protein | - |
| HXT63_RS26410 | 10198..10474 | - | 277 | Protein_11 | IS3 family transposase | - |
| HXT63_RS26415 | 10819..11559 | + | 741 | Protein_12 | tyrosine-type recombinase/integrase | - |
| HXT63_RS26420 | 12381..13391 | - | 1011 | WP_017900946.1 | RepB family plasmid replication initiator protein | - |
| HXT63_RS26425 | 14121..15287 | + | 1167 | WP_023287153.1 | plasmid-partitioning protein SopA | - |
| HXT63_RS26430 | 15287..16258 | + | 972 | WP_004117790.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HXT63_RS26435 | 17539..17767 | - | 229 | Protein_16 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| HXT63_RS26440 | 17846..18140 | - | 295 | Protein_17 | DUF4113 domain-containing protein | - |
| HXT63_RS26445 | 18225..18665 | + | 441 | WP_040027444.1 | transposase | - |
| HXT63_RS26450 | 18662..19012 | + | 351 | WP_004189161.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| HXT63_RS26455 | 19043..20635 | + | 1593 | WP_237086701.1 | IS66-like element ISKox1 family transposase | - |
| HXT63_RS26460 | 20701..20817 | + | 117 | Protein_21 | transposase | - |
| HXT63_RS26465 | 20830..21798 | - | 969 | WP_004213807.1 | IS110 family transposase | - |
| HXT63_RS26470 | 21966..23041 | + | 1076 | Protein_23 | IS3 family transposase | - |
| HXT63_RS26475 | 23062..23505 | + | 444 | WP_020477096.1 | hypothetical protein | - |
| HXT63_RS26480 | 23515..23922 | + | 408 | WP_004186937.1 | hypothetical protein | - |
| HXT63_RS26485 | 23965..24924 | + | 960 | WP_102054602.1 | DNA replication terminus site-binding protein | - |
| HXT63_RS26490 | 24921..25679 | + | 759 | WP_063938344.1 | hypothetical protein | - |
| HXT63_RS26495 | 25676..25999 | + | 324 | WP_004197568.1 | hypothetical protein | - |
| HXT63_RS26500 | 26151..26468 | + | 318 | WP_004213829.1 | hypothetical protein | - |
| HXT63_RS26505 | 26534..27022 | - | 489 | WP_237086702.1 | tyrosine-type recombinase/integrase | - |
| HXT63_RS26510 | 27180..28148 | - | 969 | WP_237086703.1 | IS5-like element IS903B family transposase | - |
| HXT63_RS26515 | 28168..28353 | + | 186 | WP_071953846.1 | DUF2188 domain-containing protein | - |
| HXT63_RS26520 | 28579..29502 | - | 924 | WP_237086704.1 | IS5 family transposase | - |
| HXT63_RS26525 | 29559..30517 | - | 959 | Protein_34 | IS5-like element IS903B family transposase | - |
| HXT63_RS26530 | 30626..31087 | + | 462 | Protein_35 | DUF4113 domain-containing protein | - |
| HXT63_RS26535 | 31187..31630 | + | 444 | WP_032413443.1 | DUF2384 domain-containing protein | Antitoxin Detail |
| HXT63_RS26540 | 31627..32097 | + | 471 | WP_004144067.1 | RES family NAD+ phosphorylase | Toxin Detail |
| HXT63_RS26545 | 32207..32467 | - | 261 | WP_237086705.1 | hypothetical protein | - |
| HXT63_RS26550 | 33039..33419 | - | 381 | Protein_39 | integrase core domain-containing protein | - |
| HXT63_RS26555 | 33476..34434 | - | 959 | Protein_40 | IS5-like element IS903B family transposase | - |
| HXT63_RS26560 | 34467..35276 | - | 810 | Protein_41 | IS481-like element ISKpn28 family transposase | - |
| HXT63_RS26565 | 35349..35510 | + | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| HXT63_RS26570 | 35746..36714 | - | 969 | WP_237086706.1 | IS5 family transposase | - |
| HXT63_RS26575 | 36969..37406 | + | 438 | Protein_44 | DDE-type integrase/transposase/recombinase | - |
| HXT63_RS26580 | 37611..37922 | + | 312 | WP_011251285.1 | type II toxin-antitoxin system HigB family toxin | Toxin Detail |
| HXT63_RS26585 | 37919..38338 | + | 420 | WP_011251286.1 | helix-turn-helix domain-containing protein | Antitoxin Detail |
| HXT63_RS26590 | 38485..39452 | + | 968 | Protein_47 | IS5 family transposase | - |
| HXT63_RS26595 | 39497..40147 | - | 651 | WP_237086707.1 | hypothetical protein | - |
| HXT63_RS26600 | 40257..40787 | - | 531 | WP_228292664.1 | hypothetical protein | - |
| HXT63_RS26605 | 41206..41775 | + | 570 | WP_228292663.1 | hypothetical protein | - |
| HXT63_RS26610 | 42787..43755 | + | 969 | WP_000654805.1 | IS5-like element IS903B family transposase | - |
| HXT63_RS26615 | 43848..44068 | - | 221 | Protein_52 | DNA polymerase V subunit UmuC | - |
| HXT63_RS26620 | 44071..44598 | - | 528 | Protein_53 | DUF969 family protein | - |
| HXT63_RS26625 | 44573..45070 | - | 498 | Protein_54 | IS5 family transposase | - |
| HXT63_RS26630 | 45293..46075 | - | 783 | WP_048268853.1 | site-specific integrase | - |
| HXT63_RS26635 | 46072..46893 | - | 822 | WP_048268865.1 | hypothetical protein | - |
| HXT63_RS26640 | 47822..48904 | + | 1083 | WP_227341193.1 | transcriptional regulator | - |
| HXT63_RS26645 | 49053..49796 | + | 744 | WP_119867221.1 | hypothetical protein | - |
| HXT63_RS26650 | 49936..50544 | - | 609 | WP_119867222.1 | toll/interleukin-1 receptor domain-containing protein | - |
| HXT63_RS26655 | 50773..51342 | - | 570 | WP_119867223.1 | hypothetical protein | - |
| HXT63_RS26660 | 51345..52487 | - | 1143 | WP_119867224.1 | toll/interleukin-1 receptor domain-containing protein | - |
| HXT63_RS26665 | 52621..54237 | - | 1617 | WP_227341191.1 | CBASS cGAMP-activated phospholipase | - |
| HXT63_RS26670 | 54399..54884 | - | 486 | WP_119867226.1 | TIR domain-containing protein | - |
| HXT63_RS26675 | 54896..55423 | - | 528 | WP_227341189.1 | toll/interleukin-1 receptor domain-containing protein | - |
| HXT63_RS26680 | 55977..56207 | + | 231 | WP_119867228.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| HXT63_RS26685 | 56204..56620 | + | 417 | WP_227341187.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HXT63_RS26690 | 56737..57705 | - | 969 | WP_237086708.1 | IS5-like element IS903B family transposase | - |
| HXT63_RS26695 | 58190..59200 | - | 1011 | WP_237086709.1 | hypothetical protein | - |
| HXT63_RS26700 | 59771..59893 | + | 123 | Protein_69 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| HXT63_RS26705 | 59924..60892 | + | 969 | WP_074443085.1 | IS5 family transposase | - |
| HXT63_RS26710 | 60950..61189 | + | 240 | Protein_71 | GNAT family N-acetyltransferase | - |
| HXT63_RS26715 | 61218..61915 | + | 698 | WP_231537464.1 | IS1 family transposase | - |
| HXT63_RS26720 | 61909..62211 | - | 303 | WP_108588601.1 | TonB family protein | - |
| HXT63_RS28295 | 62595..62726 | - | 132 | WP_004218042.1 | hypothetical protein | - |
| HXT63_RS26725 | 62887..64233 | - | 1347 | WP_237086710.1 | ISNCY family transposase | - |
| HXT63_RS26730 | 64444..64926 | - | 483 | WP_130972229.1 | GNAT family N-acetyltransferase | Toxin Detail |
| HXT63_RS26735 | 64914..65180 | - | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| HXT63_RS26740 | 65835..66059 | - | 225 | WP_237086711.1 | hypothetical protein | - |
| HXT63_RS26745 | 66034..66327 | - | 294 | WP_227341177.1 | hypothetical protein | - |
| HXT63_RS26750 | 66358..66930 | - | 573 | WP_227341175.1 | hypothetical protein | - |
| HXT63_RS26755 | 66927..67175 | - | 249 | WP_227341173.1 | hypothetical protein | - |
| HXT63_RS26760 | 67794..68210 | + | 417 | WP_100676520.1 | hypothetical protein | - |
| HXT63_RS26765 | 68263..68943 | - | 681 | WP_049141606.1 | hypothetical protein | - |
| HXT63_RS26770 | 69255..70280 | - | 1026 | WP_100676521.1 | Abi family protein | - |
| HXT63_RS26775 | 70422..71003 | - | 582 | WP_227341171.1 | hypothetical protein | - |
| HXT63_RS26780 | 71581..72714 | + | 1134 | WP_100676526.1 | DUF3800 domain-containing protein | - |
| HXT63_RS26785 | 72730..73023 | + | 294 | WP_227341170.1 | korC | - |
| HXT63_RS26790 | 73212..74180 | - | 969 | WP_074443085.1 | IS5 family transposase | - |
| HXT63_RS26795 | 74206..74547 | - | 342 | Protein_89 | GNAT family N-acetyltransferase | - |
| HXT63_RS26800 | 74712..75832 | + | 1121 | WP_237086712.1 | IS3-like element ISKpn34 family transposase | - |
| HXT63_RS26805 | 75949..76581 | + | 633 | Protein_91 | IS3 family transposase | - |
| HXT63_RS26810 | 77532..77648 | + | 117 | Protein_92 | transposase | - |
| HXT63_RS26815 | 77836..78804 | + | 969 | WP_237086713.1 | IS5-like element IS903B family transposase | - |
| HXT63_RS26820 | 78879..79085 | + | 207 | WP_224451384.1 | AlpA family phage regulatory protein | - |
| HXT63_RS26825 | 79147..79380 | + | 234 | WP_048289775.1 | AlpA family phage regulatory protein | - |
| HXT63_RS26830 | 79563..80195 | + | 633 | WP_237086714.1 | DUF2971 domain-containing protein | - |
| HXT63_RS26835 | 80502..81470 | + | 969 | WP_080929811.1 | IS5 family transposase | - |
| HXT63_RS26840 | 81515..82756 | - | 1242 | WP_237086715.1 | site-specific integrase | - |
| HXT63_RS26845 | 82932..83746 | + | 815 | Protein_99 | IS110 family transposase | - |
| HXT63_RS26850 | 84166..85131 | - | 966 | WP_017901242.1 | DMT family transporter | - |
| HXT63_RS26855 | 85128..85946 | - | 819 | WP_017901243.1 | amino acid ABC transporter ATP-binding protein | - |
| HXT63_RS26860 | 85951..86613 | - | 663 | WP_017901244.1 | amino acid ABC transporter permease | - |
| HXT63_RS26865 | 86610..87281 | - | 672 | WP_017901245.1 | amino acid ABC transporter permease | - |
| HXT63_RS26870 | 87305..88153 | - | 849 | WP_004118155.1 | transporter substrate-binding domain-containing protein | - |
| HXT63_RS26875 | 88310..89263 | + | 954 | WP_020481021.1 | LysR substrate-binding domain-containing protein | - |
| HXT63_RS26880 | 89350..90561 | + | 1212 | WP_017901247.1 | M24 family metallopeptidase | - |
| HXT63_RS26885 | 91065..92030 | - | 966 | WP_237086698.1 | IS5-like element IS903B family transposase | - |
| HXT63_RS26890 | 92063..92638 | + | 576 | Protein_108 | IS66 family transposase | - |
| HXT63_RS26895 | 92838..93272 | - | 435 | WP_016151366.1 | hypothetical protein | - |
| HXT63_RS26900 | 93488..94888 | - | 1401 | WP_002436614.1 | copper resistance membrane spanning protein PcoS | - |
| HXT63_RS26905 | 94885..95565 | - | 681 | WP_001188930.1 | copper response regulator transcription factor PcoR | - |
| HXT63_RS26910 | 95620..96549 | - | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| HXT63_RS26915 | 96554..96934 | - | 381 | WP_032442626.1 | copper resistance system metallochaperone PcoC | - |
| HXT63_RS26920 | 96974..97864 | - | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| HXT63_RS26925 | 97870..99687 | - | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| HXT63_RS26930 | 99921..100370 | + | 450 | WP_001023257.1 | copper resistance protein | - |
| HXT63_RS26935 | 100659..101396 | + | 738 | WP_000287501.1 | peptidoglycan DD-metalloendopeptidase family protein | - |
| HXT63_RS26940 | 101430..101627 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| HXT63_RS26945 | 101668..104115 | - | 2448 | WP_032738470.1 | Ag(+)-translocating P-type ATPase SilP | - |
| HXT63_RS26950 | 104242..104682 | - | 441 | WP_000758228.1 | DUF411 domain-containing protein | - |
| HXT63_RS26955 | 104769..107915 | - | 3147 | WP_237086699.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| HXT63_RS26960 | 107926..109218 | - | 1293 | WP_004098959.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| HXT63_RS26965 | 109332..109685 | - | 354 | WP_004098961.1 | cation efflux system protein CusF | - |
| HXT63_RS26970 | 109714..111099 | - | 1386 | WP_004098962.1 | Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC | - |
| HXT63_RS26975 | 111289..111969 | + | 681 | WP_000697969.1 | copper/silver response regulator transcription factor SilR | - |
| HXT63_RS26980 | 111962..113437 | + | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| HXT63_RS26985 | 113688..114119 | + | 432 | WP_000790483.1 | silver-binding protein SilE | - |
| HXT63_RS26990 | 114281..115247 | - | 967 | Protein_128 | IS5 family transposase | - |
| HXT63_RS26995 | 115327..115677 | + | 351 | WP_000694953.1 | DUF305 domain-containing protein | - |
| HXT63_RS27000 | 116064..116972 | - | 909 | WP_001372261.1 | HNH endonuclease | - |
| HXT63_RS27005 | 117427..118337 | - | 911 | Protein_131 | IS5 family transposase | - |
| HXT63_RS27010 | 118662..119636 | + | 975 | WP_004213565.1 | sensor domain-containing diguanylate cyclase | - |
| HXT63_RS27015 | 119992..120342 | + | 351 | WP_004206664.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| HXT63_RS27020 | 120394..120756 | + | 363 | WP_004206665.1 | arsenite efflux transporter metallochaperone ArsD | - |
| HXT63_RS27025 | 120774..122525 | + | 1752 | WP_016151356.1 | arsenite efflux transporter ATPase subunit ArsA | - |
| HXT63_RS27030 | 122573..123862 | + | 1290 | WP_016151355.1 | arsenite efflux transporter membrane subunit ArsB | - |
| HXT63_RS27035 | 123875..124300 | + | 426 | WP_007779002.1 | glutaredoxin-dependent arsenate reductase | - |
| HXT63_RS27040 | 124333..124761 | - | 429 | WP_004206671.1 | GNAT family N-acetyltransferase | - |
| HXT63_RS27045 | 124883..126640 | - | 1758 | WP_016151354.1 | arsenical pump-driving ATPase | - |
| HXT63_RS27050 | 126659..127021 | - | 363 | WP_016151353.1 | arsenic metallochaperone ArsD family protein | - |
| HXT63_RS27055 | 127097..127642 | - | 546 | WP_016151352.1 | sigma-70 family RNA polymerase sigma factor | - |
| HXT63_RS27060 | 127651..128364 | - | 714 | WP_016151351.1 | arsenical resistance protein ArsH | - |
| HXT63_RS27065 | 128361..128687 | - | 327 | WP_016151350.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| HXT63_RS27070 | 129019..129516 | + | 498 | WP_007871777.1 | GNAT family N-acetyltransferase | - |
| HXT63_RS27075 | 129566..129727 | - | 162 | Protein_145 | aquaporin | - |
| HXT63_RS27080 | 129784..130752 | - | 969 | WP_016151349.1 | IS5 family transposase | - |
| HXT63_RS27085 | 130826..131311 | + | 486 | Protein_147 | FAD-dependent oxidoreductase | - |
| HXT63_RS27090 | 131378..132358 | + | 981 | WP_000019473.1 | IS5-like element ISKpn26 family transposase | - |
| HXT63_RS27095 | 132506..133351 | + | 846 | Protein_149 | FAD-dependent oxidoreductase | - |
| HXT63_RS27100 | 133554..133636 | + | 83 | Protein_150 | hypothetical protein | - |
| HXT63_RS27105 | 133672..134754 | + | 1083 | WP_007851507.1 | DNA-binding transcriptional repressor LacI | - |
| HXT63_RS27110 | 134876..137950 | + | 3075 | WP_007894989.1 | beta-galactosidase | - |
| HXT63_RS27115 | 138002..139255 | + | 1254 | WP_071080913.1 | lactose permease | - |
| HXT63_RS27120 | 139321..139461 | + | 141 | Protein_154 | maltose acetyltransferase domain-containing protein | - |
| HXT63_RS27125 | 139476..140170 | - | 695 | Protein_155 | IS1 family transposase | - |
| HXT63_RS27130 | 140359..140619 | - | 261 | WP_004118092.1 | DUF2534 family protein | - |
| HXT63_RS27135 | 140676..142739 | - | 2064 | WP_071080914.1 | TonB-dependent copper receptor | - |
| HXT63_RS27140 | 142822..143220 | - | 399 | WP_228990980.1 | DUF2946 domain-containing protein | - |
| HXT63_RS27145 | 143602..144606 | + | 1005 | WP_000427619.1 | IS110-like element IS5075 family transposase | - |
| HXT63_RS27150 | 144878..144964 | - | 87 | Protein_160 | Arm DNA-binding domain-containing protein | - |
| HXT63_RS27155 | 145294..146109 | + | 816 | WP_001043260.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | - |
| HXT63_RS27160 | 146196..146438 | + | 243 | Protein_162 | phosphoglucosamine mutase | - |
| HXT63_RS27165 | 146681..148173 | - | 1493 | Protein_163 | IS91-like element ISVsa3 family transposase | - |
| HXT63_RS27170 | 148285..148590 | - | 306 | WP_001255015.1 | LysR family transcriptional regulator | - |
| HXT63_RS27175 | 148618..149832 | - | 1215 | WP_000214122.1 | chloramphenicol/florfenicol efflux MFS transporter FloR | - |
| HXT63_RS27180 | 150049..150933 | - | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| HXT63_RS27185 | 150964..151794 | - | 831 | Protein_167 | IS91-like element ISVsa3 family transposase | - |
| HXT63_RS27190 | 151858..152562 | + | 705 | WP_001067784.1 | IS6-like element IS1006 family transposase | - |
| HXT63_RS27195 | 152647..152979 | - | 333 | WP_223366082.1 | hypothetical protein | - |
| HXT63_RS27200 | 153301..154304 | - | 1004 | Protein_170 | IS110-like element IS4321 family transposase | - |
| HXT63_RS27205 | 154383..157334 | - | 2952 | WP_015344976.1 | Tn3-like element TnAs3 family transposase | - |
| HXT63_RS27210 | 157337..157897 | - | 561 | WP_000147567.1 | recombinase family protein | - |
| HXT63_RS27215 | 158023..158373 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| HXT63_RS27220 | 158576..159589 | - | 1014 | WP_000845048.1 | class 1 integron integrase IntI1 | - |
| HXT63_RS27225 | 159734..160231 | + | 498 | WP_001083725.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | - |
| HXT63_RS27230 | 160343..160633 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| HXT63_RS27235 | 160639..161477 | + | 839 | Protein_177 | AadA family aminoglycoside 3''-O-nucleotidyltransferase | - |
| HXT63_RS27240 | 161577..161663 | + | 87 | Protein_178 | hypothetical protein | - |
| HXT63_RS27245 | 161992..163191 | - | 1200 | WP_015344972.1 | IS91 family transposase | - |
| HXT63_RS27250 | 163358..163750 | + | 393 | WP_004193041.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| HXT63_RS27255 | 164070..164474 | - | 405 | WP_064732565.1 | bleomycin binding protein | - |
| HXT63_RS27260 | 164484..165188 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| HXT63_RS27265 | 165339..166154 | + | 816 | WP_000018329.1 | aminoglycoside O-phosphotransferase APH(3')-Ia | - |
| HXT63_RS27270 | 166344..167048 | - | 705 | WP_001067834.1 | IS6-like element IS26 family transposase | - |
| HXT63_RS27275 | 167226..167876 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| HXT63_RS27280 | 167999..169180 | + | 1182 | WP_152931482.1 | tetracycline efflux MFS transporter Tet(A) | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|