MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 128537 bp
Accession: NZ_CP056115 Location: 1..128537 Organism: Escherichia coli strain Ec394-330266 Replicon: plasmid pEC394-330266_128
Accession: NZ_CP056115 Location: 1..128537 Organism: Escherichia coli strain Ec394-330266 Replicon: plasmid pEC394-330266_128
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HWD38_RS24730 | 1..858 | + | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| HWD38_RS24735 (HWD38_24445) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| HWD38_RS24740 (HWD38_24450) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| HWD38_RS24745 (HWD38_24455) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| HWD38_RS24750 (HWD38_24460) | 3271..6168 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| HWD38_RS24755 (HWD38_24465) | 6263..6868 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| HWD38_RS24760 (HWD38_24470) | 6892..7113 | - | 222 | Protein_6 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HWD38_RS24765 (HWD38_24475) | 7176..7880 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HWD38_RS24770 (HWD38_24480) | 8002..8907 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| HWD38_RS24775 (HWD38_24485) | 8904..10142 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| HWD38_RS24780 (HWD38_24490) | 10142..10726 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| HWD38_RS24785 (HWD38_24495) | 11219..11983 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| HWD38_RS24790 (HWD38_24500) | 12101..12166 | - | 66 | Protein_12 | EAL domain-containing protein | - |
| HWD38_RS24795 (HWD38_24505) | 12210..12515 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| HWD38_RS24800 (HWD38_24510) | 12526..13731 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| HWD38_RS24805 (HWD38_24515) | 13887..14090 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| HWD38_RS24810 (HWD38_24520) | 14218..15057 | - | 840 | WP_000259031.1 | hypothetical protein | ARG |
| HWD38_RS24815 (HWD38_24525) | 15051..15398 | - | 348 | WP_000679427.1 | Spermidine export protein MdtJ | ARG |
| HWD38_RS24820 (HWD38_24530) | 15604..16392 | - | 789 | WP_000503573.1 | hypothetical protein | ARG |
| HWD38_RS24825 (HWD38_24535) | 16523..16996 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| HWD38_RS24830 (HWD38_24540) | 17154..18167 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| HWD38_RS24835 (HWD38_24545) | 18370..18720 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| HWD38_RS24840 (HWD38_24550) | 18846..19013 | + | 168 | Protein_22 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| HWD38_RS24845 (HWD38_24555) | 19066..19770 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HWD38_RS24850 (HWD38_24560) | 19906..20781 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| HWD38_RS24855 (HWD38_24565) | 20828..21121 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| HWD38_RS24860 (HWD38_24570) | 21186..23405 | + | 2220 | Protein_26 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HWD38_RS24865 (HWD38_24575) | 23482..24186 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HWD38_RS24870 (HWD38_24580) | 24240..24680 | - | 441 | Protein_28 | CatB-related O-acetyltransferase | - |
| HWD38_RS24875 (HWD38_24585) | 24818..25648 | - | 831 | WP_001334766.1 | hypothetical protein | ARG |
| HWD38_RS24880 (HWD38_24590) | 25779..26333 | - | 555 | WP_063840321.1 | hypothetical protein | ARG |
| HWD38_RS24885 (HWD38_24595) | 26477..27181 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HWD38_RS24890 (HWD38_24600) | 27258..29477 | - | 2220 | Protein_32 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HWD38_RS24895 (HWD38_24605) | 29542..29835 | + | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| HWD38_RS24900 (HWD38_24610) | 29882..30757 | - | 876 | WP_000239590.1 | hypothetical protein | ARG |
| HWD38_RS24905 (HWD38_24615) | 30893..31597 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HWD38_RS24910 (HWD38_24620) | 31650..31817 | - | 168 | Protein_36 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| HWD38_RS24915 (HWD38_24625) | 31943..32293 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| HWD38_RS24920 (HWD38_24630) | 32496..33509 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| HWD38_RS24925 (HWD38_24635) | 33667..34140 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| HWD38_RS24930 (HWD38_24640) | 34271..35059 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| HWD38_RS24935 (HWD38_24645) | 35265..35612 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| HWD38_RS24940 (HWD38_24650) | 35606..36445 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| HWD38_RS24945 (HWD38_24655) | 36573..36776 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| HWD38_RS24950 (HWD38_24660) | 36932..38137 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| HWD38_RS24955 (HWD38_24665) | 38148..38453 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| HWD38_RS24960 (HWD38_24670) | 38497..38562 | + | 66 | Protein_46 | EAL domain-containing protein | - |
| HWD38_RS24965 (HWD38_24675) | 38680..39444 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| HWD38_RS24970 (HWD38_24680) | 39937..40521 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| HWD38_RS24975 (HWD38_24685) | 40521..41759 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| HWD38_RS24980 (HWD38_24690) | 41756..42661 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| HWD38_RS24985 (HWD38_24695) | 42783..43487 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HWD38_RS24990 (HWD38_24700) | 43767..44528 | + | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| HWD38_RS24995 (HWD38_24705) | 44875..46761 | + | 1887 | WP_000118029.1 | FTR1 family protein | - |
| HWD38_RS25000 (HWD38_24710) | 46802..47329 | + | 528 | WP_000178050.1 | iron transporter | - |
| HWD38_RS25005 (HWD38_24715) | 47433..48812 | + | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| HWD38_RS25010 (HWD38_24720) | 48815..50098 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| HWD38_RS25015 (HWD38_24725) | 50088..51218 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| HWD38_RS25020 (HWD38_24730) | 51223..51918 | + | 696 | WP_000117262.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| HWD38_RS25025 (HWD38_24735) | 51905..52390 | + | 486 | WP_001267177.1 | TlpA disulfide reductase family protein | - |
| HWD38_RS25030 (HWD38_24740) | 52415..52900 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| HWD38_RS25035 (HWD38_24745) | 53022..53552 | + | 531 | Protein_61 | histidine-type phosphatase | - |
| HWD38_RS25040 (HWD38_24750) | 53610..54314 | - | 705 | WP_001067855.1 | IS3 family transposase IS1203 | Transposase |
| HWD38_RS25045 (HWD38_24755) | 54339..55535 | + | 1197 | Protein_63 | IS3 family transposase | - |
| HWD38_RS25050 (HWD38_24760) | 55617..55790 | + | 174 | WP_000338295.1 | Tn3 family transposase ISPsy39 | Transposase |
| HWD38_RS25055 (HWD38_24765) | 55867..56175 | + | 309 | Protein_65 | IS4 family transposase ISEc13 | Transposase |
| HWD38_RS25060 (HWD38_24770) | 56234..57544 | - | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| HWD38_RS25065 (HWD38_24775) | 57537..58610 | - | 1074 | WP_000950177.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| HWD38_RS25070 (HWD38_24780) | 58616..59440 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| HWD38_RS25075 (HWD38_24785) | 59451..60338 | - | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| HWD38_RS25080 (HWD38_24790) | 60328..61206 | - | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| HWD38_RS25085 (HWD38_24795) | 61337..61777 | - | 441 | Protein_71 | zinc-binding dehydrogenase | - |
| HWD38_RS25090 (HWD38_24800) | 61751..61945 | + | 195 | WP_000796505.1 | hypothetical protein | - |
| HWD38_RS25095 (HWD38_24805) | 62178..63068 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| HWD38_RS25100 (HWD38_24810) | 63093..63473 | + | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| HWD38_RS25105 (HWD38_24815) | 63506..64471 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| HWD38_RS25110 (HWD38_24820) | 64517..65269 | - | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| HWD38_RS25115 (HWD38_24825) | 65874..66158 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| HWD38_RS25120 (HWD38_24830) | 66158..66433 | + | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| HWD38_RS25125 (HWD38_24835) | 66539..66742 | + | 204 | Protein_79 | hypothetical protein | - |
| HWD38_RS25130 (HWD38_24840) | 66867..66995 | - | 129 | Protein_80 | IS481 family transposase | - |
| HWD38_RS25135 (HWD38_24845) | 67028..68197 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| HWD38_RS25140 (HWD38_24850) | 68729..68997 | + | 269 | Protein_82 | type II toxin-antitoxin system ParD family antitoxin | - |
| HWD38_RS25145 | 68984..69252 | + | 269 | Protein_83 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HWD38_RS25150 (HWD38_24855) | 69286..69983 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| HWD38_RS25155 (HWD38_24860) | 70237..71259 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| HWD38_RS25160 (HWD38_24865) | 71244..72809 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| HWD38_RS25165 (HWD38_24870) | 72884..73300 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HWD38_RS25170 (HWD38_24875) | 73297..73527 | - | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| HWD38_RS25175 (HWD38_24880) | 73908..77702 | + | 3795 | WP_001144732.1 | hypothetical protein | - |
| HWD38_RS25180 (HWD38_24885) | 77747..78163 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HWD38_RS25185 (HWD38_24890) | 78160..78390 | - | 231 | WP_001261278.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| HWD38_RS25190 (HWD38_24895) | 78655..79155 | + | 501 | WP_000528932.1 | HEPN family nuclease | - |
| HWD38_RS25195 (HWD38_24900) | 79168..79941 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| HWD38_RS25200 (HWD38_24905) | 80152..81765 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| HWD38_RS25205 (HWD38_24910) | 81796..82146 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| HWD38_RS25210 (HWD38_24915) | 82143..82568 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| HWD38_RS25215 (HWD38_24920) | 82660..83781 | + | 1122 | WP_012783980.1 | DUF3800 domain-containing protein | - |
| HWD38_RS25220 (HWD38_24925) | 83815..84303 | - | 489 | WP_011254646.1 | hypothetical protein | - |
| HWD38_RS25225 (HWD38_24930) | 84873..85091 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| HWD38_RS25230 (HWD38_24935) | 85093..85398 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| HWD38_RS25235 (HWD38_24940) | 85399..86205 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| HWD38_RS25240 (HWD38_24945) | 86979..87734 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| HWD38_RS25245 (HWD38_24950) | 88322..89488 | + | 1167 | WP_000772446.1 | hypothetical protein | VF |
| HWD38_RS25250 (HWD38_24955) | 89488..90459 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HWD38_RS25255 (HWD38_24960) | 91326..92228 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| HWD38_RS25260 (HWD38_24965) | 92225..92536 | + | 312 | WP_011254640.1 | hypothetical protein | - |
| HWD38_RS25265 (HWD38_24970) | 92613..93296 | + | 684 | WP_000086185.1 | DNA methylase | - |
| HWD38_RS25270 (HWD38_24975) | 93297..93518 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| HWD38_RS25275 (HWD38_24980) | 93448..93966 | + | 519 | WP_123325260.1 | DUF1380 family protein | - |
| HWD38_RS25280 (HWD38_24985) | 94017..94793 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| HWD38_RS25285 (HWD38_24990) | 95210..95635 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| HWD38_RS25290 (HWD38_24995) | 95682..96104 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| HWD38_RS25295 (HWD38_25000) | 96101..96292 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| HWD38_RS25300 (HWD38_25005) | 97327..97557 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| HWD38_RS25305 (HWD38_25010) | 97609..98970 | + | 1362 | WP_000170728.1 | DUF3560 domain-containing protein | - |
| HWD38_RS25310 (HWD38_25015) | 99017..99580 | + | 564 | WP_012783964.1 | class I SAM-dependent methyltransferase | - |
| HWD38_RS25315 | 99580..99804 | + | 225 | WP_021538344.1 | hypothetical protein | - |
| HWD38_RS25320 | 99732..99974 | + | 243 | WP_001365577.1 | hypothetical protein | - |
| HWD38_RS25325 (HWD38_25020) | 101096..101737 | + | 642 | WP_235692175.1 | reverse transcriptase domain-containing protein | - |
| HWD38_RS25330 (HWD38_25025) | 101628..102296 | - | 669 | WP_042630750.1 | IS6 family transposase IS15DI | Transposase |
| HWD38_RS25335 (HWD38_25030) | 102309..102946 | + | 638 | Protein_121 | conjugal transfer pilus assembly protein TraU | - |
| HWD38_RS25340 (HWD38_25035) | 102976..103281 | + | 306 | WP_000224416.1 | hypothetical protein | - |
| HWD38_RS25345 (HWD38_25040) | 103290..103928 | + | 639 | WP_001080256.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HWD38_RS25350 (HWD38_25045) | 103925..105775 | + | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HWD38_RS25355 (HWD38_25050) | 105802..106059 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| HWD38_RS25360 (HWD38_25055) | 106052..106795 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HWD38_RS25365 (HWD38_25060) | 106809..107153 | + | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| HWD38_RS25370 (HWD38_25065) | 107272..107556 | + | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HWD38_RS25375 (HWD38_25070) | 107543..108088 | + | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HWD38_RS25380 (HWD38_25075) | 108018..108365 | + | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| HWD38_RS25385 (HWD38_25080) | 108346..108738 | + | 393 | WP_000660699.1 | F-type conjugal transfer protein TrbF | - |
| HWD38_RS25390 (HWD38_25085) | 108725..110098 | + | 1374 | WP_000944331.1 | conjugal transfer pilus assembly protein TraH | - |
| HWD38_RS25395 (HWD38_25090) | 110095..112917 | + | 2823 | WP_001007039.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| HWD38_RS25400 (HWD38_25095) | 112933..113418 | + | 486 | WP_000605870.1 | hypothetical protein | - |
| HWD38_RS25405 (HWD38_25100) | 113467..114198 | + | 732 | WP_000782451.1 | conjugal transfer complement resistance protein TraT | - |
| HWD38_RS25410 (HWD38_25105) | 114401..115138 | + | 738 | WP_000199905.1 | hypothetical protein | - |
| HWD38_RS25415 (HWD38_25110) | 115189..117414 | + | 2226 | WP_011867779.1 | type IV conjugative transfer system coupling protein TraD | - |
| HWD38_RS25420 (HWD38_25115) | 117414..122684 | + | 5271 | WP_000948354.1 | ATP-dependent RecD-like DNA helicase | Relaxase |
| HWD38_RS25425 (HWD38_25120) | 122704..123450 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| HWD38_RS25430 (HWD38_25125) | 123509..124369 | + | 861 | WP_000704523.1 | hypothetical protein | VF |
| HWD38_RS25435 (HWD38_25130) | 124472..125032 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| HWD38_RS25440 (HWD38_25135) | 125161..125373 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| HWD38_RS25445 (HWD38_25140) | 125653..126350 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| HWD38_RS25450 (HWD38_25145) | 126395..126856 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| HWD38_RS25455 (HWD38_25150) | 126902..127111 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| HWD38_RS25460 (HWD38_25155) | 127149..127739 | + | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| HWD38_RS25465 (HWD38_25160) | 127979..128233 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| HWD38_RS25470 | 128340..128525 | + | 186 | WP_012615301.1 | plasmid copy control protein CopA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|