MGE detailed information
MGE type: Conjugative plasmid MGE length: 131772 bp
Accession: NZ_CP055171 Location: 1..131772 Organism: Shigella flexneri strain STEFF_22 Replicon: plasmid unnamed1
Accession: NZ_CP055171 Location: 1..131772 Organism: Shigella flexneri strain STEFF_22 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUZ49_RS23150 (1) | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| HUZ49_RS23155 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| HUZ49_RS23160 (2124) | 2124..2319 | - | 196 | Protein_2 | serine/threonine protein kinase | - |
| HUZ49_RS23165 (2406) | 2406..2816 | - | 411 | Protein_3 | IS3 family transposase ISEhe3 | Transposase |
| HUZ49_RS23170 (2879) | 2879..3583 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ49_RS23175 (3637) | 3637..4104 | + | 468 | Protein_5 | conjugal transfer protein | - |
| HUZ49_RS23180 (4349) | 4349..4465 | + | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| HUZ49_RS23185 (4481) | 4481..6400 | + | 1920 | WP_025989258.1 | Tetracycline resistance protein TetM from transposon TnFO1 | VF |
| HUZ49_RS23190 (6519) | 6519..6686 | + | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| HUZ49_RS23195 (6947) | 6947..7579 | + | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| HUZ49_RS23200 (7826) | 7826..8158 | - | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| HUZ49_RS23205 (8281) | 8281..9119 | - | 839 | Protein_11 | Streptomycin 3''-adenylyltransferase | ARG |
| HUZ49_RS23210 (9212) | 9212..10471 | - | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| HUZ49_RS23215 (10686) | 10686..11524 | - | 839 | Protein_13 | Streptomycin 3''-adenylyltransferase | ARG |
| HUZ49_RS23220 (11530) | 11530..11820 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| HUZ49_RS23225 (11932) | 11932..12429 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| HUZ49_RS23230 (12574) | 12574..13587 | + | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| HUZ49_RS23235 (13790) | 13790..14140 | + | 351 | WP_071830595.1 | DUF3330 domain-containing protein | - |
| HUZ49_RS23240 (14266) | 14266..14826 | + | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| HUZ49_RS23245 (14829) | 14829..17780 | + | 2952 | WP_015344976.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| HUZ49_RS23250 (17714) | 17714..18190 | + | 477 | WP_223171565.1 | hypothetical protein | - |
| HUZ49_RS23255 (18275) | 18275..18979 | - | 705 | WP_001067784.1 | IS6 family transposase IS1006 | Transposase |
| HUZ49_RS23260 (19043) | 19043..19873 | + | 831 | Protein_22 | IS91 family transposase ISVsa3 | Transposase |
| HUZ49_RS23265 (19904) | 19904..20788 | + | 885 | WP_239591999.1 | DUF3363 domain-containing protein | - |
| HUZ49_RS23270 (21005) | 21005..22219 | + | 1215 | WP_058657119.1 | Bicyclomycin resistance protein | ARG |
| HUZ49_RS23275 (22247) | 22247..22552 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| HUZ49_RS23280 (22664) | 22664..24157 | + | 1494 | WP_015344975.1 | IS91 family transposase ISVsa3 | Transposase |
| HUZ49_RS23285 (24393) | 24393..24635 | - | 243 | Protein_27 | phosphoglucosamine mutase | - |
| HUZ49_RS23290 (24722) | 24722..25537 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| HUZ49_RS23295 (25627) | 25627..26717 | + | 1091 | WP_085940648.1 | IS4 family transposase ISAba1 | Transposase |
| HUZ49_RS23300 (26914) | 26914..27201 | - | 288 | WP_230071785.1 | hypothetical protein | - |
| HUZ49_RS23305 (27449) | 27449..28153 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ49_RS23310 (28219) | 28219..29733 | + | 1515 | Protein_32 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUZ49_RS23315 (29791) | 29791..30033 | + | 243 | WP_000844627.1 | transposase | - |
| HUZ49_RS23320 (30065) | 30065..30715 | - | 651 | WP_001493764.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| HUZ49_RS23325 (30821) | 30821..32020 | + | 1200 | WP_001493765.1 | Tetracycline resistance protein, class C | ARG |
| HUZ49_RS23330 (32052) | 32052..32936 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| HUZ49_RS23335 (33074) | 33074..33508 | - | 435 | WP_223963367.1 | isochorismatase family cysteine hydrolase | - |
| HUZ49_RS23340 (33471) | 33471..35132 | + | 1662 | Protein_38 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUZ49_RS23345 (35234) | 35234..35491 | + | 258 | WP_231363335.1 | hypothetical protein | - |
| HUZ49_RS23350 (35600) | 35600..36304 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ49_RS23355 (36494) | 36494..37309 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HUZ49_RS23360 (37460) | 37460..38164 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ49_RS23365 (38216) | 38216..38467 | + | 252 | Protein_43 | hypothetical protein | - |
| HUZ49_RS23370 (38613) | 38613..39476 | + | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| HUZ49_RS23375 (39514) | 39514..39759 | + | 246 | WP_001354008.1 | GrpB family protein | - |
| HUZ49_RS23380 (40228) | 40228..41019 | + | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| HUZ49_RS23385 (41277) | 41277..42137 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| HUZ49_RS23390 (42320) | 42320..42877 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HUZ49_RS23395 (43169) | 43169..43873 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ49_RS23400 (44026) | 44026..44847 | - | 822 | WP_000939727.1 | hypothetical protein | ARG |
| HUZ49_RS23405 (44932) | 44932..45770 | - | 839 | Protein_51 | Streptomycin 3''-adenylyltransferase | ARG |
| HUZ49_RS23410 (45919) | 45919..46716 | + | 798 | Protein_52 | IS91 family transposase ISMno23 | Transposase |
| HUZ49_RS23415 (46769) | 46769..47473 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ49_RS23420 (48010) | 48010..48552 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| HUZ49_RS23425 (48565) | 48565..49425 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| HUZ49_RS23430 (49568) | 49568..50062 | + | 495 | Protein_56 | IS4 family transposase IS10R | Transposase |
| HUZ49_RS23435 (50116) | 50116..50820 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HUZ49_RS23440 (50888) | 50888..52186 | + | 1299 | Protein_58 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUZ49_RS23445 (52220) | 52220..52720 | + | 501 | Protein_59 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUZ49_RS23450 (52754) | 52754..52942 | + | 189 | Protein_60 | IS3 family transposase | - |
| HUZ49_RS23455 (53017) | 53017..53304 | - | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| HUZ49_RS23460 (53301) | 53301..53552 | - | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| HUZ49_RS23465 (54518) | 54518..55375 | - | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| HUZ49_RS23470 (55368) | 55368..55442 | - | 75 | WP_061357229.1 | RepA leader peptide Tap | - |
| HUZ49_RS23475 (55674) | 55674..55931 | - | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| HUZ49_RS23480 (56199) | 56199..56348 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (56392) | 56392..56453 | + | 62 | NuclAT_1 | - | - |
| - (56392) | 56392..56453 | + | 62 | NuclAT_1 | - | - |
| - (56392) | 56392..56453 | + | 62 | NuclAT_1 | - | - |
| - (56392) | 56392..56453 | + | 62 | NuclAT_1 | - | - |
| HUZ49_RS23485 (56795) | 56795..57007 | - | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| HUZ49_RS23490 (57142) | 57142..57702 | - | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| HUZ49_RS23495 (57757) | 57757..58500 | - | 744 | WP_039002216.1 | conjugal transfer pilus acetylase TraX | - |
| HUZ49_RS23500 (58520) | 58520..63790 | - | 5271 | WP_239592000.1 | Multifunctional conjugation protein TraI | Relaxase |
| HUZ49_RS23505 (63790) | 63790..65970 | - | 2181 | WP_063078088.1 | type IV conjugative transfer system coupling protein TraD | - |
| HUZ49_RS23510 (66223) | 66223..66954 | - | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| HUZ49_RS23515 (66986) | 66986..67489 | - | 504 | WP_000605510.1 | hypothetical protein | - |
| HUZ49_RS23520 (67504) | 67504..70326 | - | 2823 | WP_001007048.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| HUZ49_RS23525 (70323) | 70323..71696 | - | 1374 | WP_170926237.1 | conjugal transfer pilus assembly protein TraH | - |
| HUZ49_RS23530 (71696) | 71696..72058 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| HUZ49_RS23535 (71988) | 71988..72533 | - | 546 | WP_000052613.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HUZ49_RS23540 (72520) | 72520..72756 | - | 237 | WP_054377141.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HUZ49_RS23545 (72917) | 72917..73660 | - | 744 | WP_039002205.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HUZ49_RS23550 (73653) | 73653..73913 | - | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| HUZ49_RS23555 (73940) | 73940..75748 | - | 1809 | WP_000821844.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HUZ49_RS23560 (75745) | 75745..76383 | - | 639 | WP_000777691.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HUZ49_RS23565 (76392) | 76392..77384 | - | 993 | WP_023148235.1 | conjugal transfer pilus assembly protein TraU | - |
| HUZ49_RS23570 (77381) | 77381..78013 | - | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| HUZ49_RS23575 (78010) | 78010..78396 | - | 387 | WP_039002198.1 | type-F conjugative transfer system protein TrbI | - |
| HUZ49_RS23580 (78393) | 78393..81020 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| HUZ49_RS23585 (81180) | 81180..81401 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| HUZ49_RS23590 (81536) | 81536..82051 | - | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HUZ49_RS23595 (82048) | 82048..82368 | - | 321 | WP_063078087.1 | conjugal transfer protein TrbD | - |
| HUZ49_RS23600 (82355) | 82355..82942 | - | 588 | WP_000002772.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| HUZ49_RS23605 (82932) | 82932..84359 | - | 1428 | WP_000146690.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| HUZ49_RS23610 (84359) | 84359..85087 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| HUZ49_RS23615 (85074) | 85074..85640 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| HUZ49_RS23620 (85662) | 85662..85973 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| HUZ49_RS23625 (85978) | 85978..86340 | - | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| HUZ49_RS23630 (86373) | 86373..86774 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| HUZ49_RS23635 (86867) | 86867..87556 | - | 690 | WP_039002187.1 | conjugal transfer transcriptional regulator TraJ | - |
| HUZ49_RS23640 (87743) | 87743..88126 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| HUZ49_RS23645 (88447) | 88447..89049 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| HUZ49_RS23650 (89346) | 89346..90167 | - | 822 | WP_072795862.1 | DUF932 domain-containing protein | - |
| HUZ49_RS23655 (90289) | 90289..90576 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| HUZ49_RS23660 (90578) | 90578..90775 | + | 198 | Protein_102 | hypothetical protein | - |
| HUZ49_RS23665 (90773) | 90773..91003 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| HUZ49_RS23670 (91223) | 91223..91348 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HUZ49_RS23675 (91290) | 91290..91439 | - | 150 | Protein_105 | plasmid maintenance protein Mok | - |
| - (91425) | 91425..91649 | - | 225 | NuclAT_0 | - | - |
| - (91425) | 91425..91649 | - | 225 | NuclAT_0 | - | - |
| - (91425) | 91425..91649 | - | 225 | NuclAT_0 | - | - |
| - (91425) | 91425..91649 | - | 225 | NuclAT_0 | - | - |
| HUZ49_RS23680 (91461) | 91461..91649 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| HUZ49_RS23685 (91661) | 91661..92380 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| HUZ49_RS23690 (92377) | 92377..92811 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| HUZ49_RS23695 (92866) | 92866..94824 | - | 1959 | WP_039000998.1 | ParB/RepB/Spo0J family partition protein | - |
| HUZ49_RS23700 (94889) | 94889..95122 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| HUZ49_RS23705 (95179) | 95179..95718 | - | 540 | WP_032332913.1 | single-stranded DNA-binding protein | - |
| HUZ49_RS23710 (95744) | 95744..95950 | - | 207 | WP_000275853.1 | hypothetical protein | - |
| HUZ49_RS23715 (96191) | 96191..96418 | - | 228 | WP_071961421.1 | hypothetical protein | - |
| HUZ49_RS23720 (96570) | 96570..97133 | - | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| HUZ49_RS23725 (97181) | 97181..98542 | - | 1362 | WP_038999961.1 | DUF3560 domain-containing protein | - |
| HUZ49_RS23730 (98594) | 98594..98824 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| HUZ49_RS23735 (99859) | 99859..100050 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| HUZ49_RS23740 (100047) | 100047..100469 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| HUZ49_RS23745 (100516) | 100516..100941 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| HUZ49_RS23750 (101358) | 101358..102134 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| HUZ49_RS23755 (102185) | 102185..102703 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| HUZ49_RS23760 (102633) | 102633..102854 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| HUZ49_RS23765 (102855) | 102855..103538 | - | 684 | WP_000086185.1 | DNA methylase | - |
| HUZ49_RS23770 (103615) | 103615..103926 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| HUZ49_RS23775 (103923) | 103923..104825 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| HUZ49_RS23780 (105243) | 105243..105491 | + | 249 | WP_000618110.1 | DinI-like family protein | - |
| HUZ49_RS23785 (105488) | 105488..105925 | + | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| HUZ49_RS23790 (105925) | 105925..107196 | + | 1272 | Protein_128 | translesion error-prone DNA polymerase V subunit UmuC | - |
| HUZ49_RS23795 (107201) | 107201..107593 | - | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| HUZ49_RS23800 (107598) | 107598..108569 | - | 972 | WP_001103690.1 | plasmid segregation protein ParM | - |
| HUZ49_RS23805 (108791) | 108791..109435 | + | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| HUZ49_RS23810 (109429) | 109429..109704 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| HUZ49_RS23815 (109856) | 109856..110632 | - | 777 | Protein_133 | site-specific integrase | - |
| HUZ49_RS23820 (110629) | 110629..111135 | - | 507 | WP_001505085.1 | hypothetical protein | - |
| HUZ49_RS23825 (111126) | 111126..111830 | + | 705 | WP_065304467.1 | IS6 family transposase IS26 | Transposase |
| HUZ49_RS23830 (111979) | 111979..113304 | - | 1326 | WP_021512928.1 | reactive chlorine resistance oxidoreductase RclA | - |
| HUZ49_RS23835 (113414) | 113414..114111 | + | 698 | WP_114161604.1 | IS1 family transposase IS1R | Transposase |
| HUZ49_RS23840 (114212) | 114212..114493 | - | 282 | WP_000639434.1 | hypothetical protein | - |
| HUZ49_RS23845 (114595) | 114595..115488 | - | 894 | Protein_139 | IS3 family transposase ISEhe3 | Transposase |
| HUZ49_RS23850 (115556) | 115556..116374 | + | 819 | Protein_140 | IS30 family transposase IS30D | Transposase |
| HUZ49_RS23860 (117709) | 117709..117858 | + | 150 | Protein_142 | IS30 family transposase IS30D | Transposase |
| HUZ49_RS23865 (118283) | 118283..118567 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| HUZ49_RS23870 (118587) | 118587..119720 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| HUZ49_RS23875 (119983) | 119983..121620 | - | 1638 | WP_223201785.1 | hypothetical protein | - |
| HUZ49_RS23880 (121671) | 121671..122501 | - | 831 | WP_223201786.1 | hypothetical protein | - |
| HUZ49_RS23885 (122553) | 122553..123101 | - | 549 | WP_039002808.1 | hypothetical protein | - |
| HUZ49_RS23890 (123407) | 123407..123637 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| HUZ49_RS23895 (123634) | 123634..124050 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HUZ49_RS23900 (124212) | 124212..126350 | - | 2139 | WP_039002805.1 | AAA family ATPase | - |
| HUZ49_RS23905 (126815) | 126815..127810 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| HUZ49_RS23910 (127853) | 127853..128746 | + | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| HUZ49_RS23920 (129728) | 129728..129886 | + | 159 | WP_228955855.1 | abortive infection family protein | - |
| HUZ49_RS23925 (130045) | 130045..131017 | - | 973 | Protein_155 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|