MGE detailed information
MGE type: Conjugative plasmid MGE length: 144275 bp
Accession: NZ_CP055071 Location: 1..144275 Organism: Shigella flexneri strain SWHIN_97 Replicon: plasmid unnamed1
Accession: NZ_CP055071 Location: 1..144275 Organism: Shigella flexneri strain SWHIN_97 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUZ91_RS23270 (1) | 1..858 | + | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| HUZ91_RS23275 (1824) | 1824..2075 | + | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| HUZ91_RS23280 (2072) | 2072..2359 | + | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| HUZ91_RS23285 (2434) | 2434..2622 | - | 189 | Protein_3 | IS3 family transposase | - |
| HUZ91_RS23290 (2656) | 2656..3156 | - | 501 | Protein_4 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUZ91_RS23295 (3190) | 3190..4488 | - | 1299 | Protein_5 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUZ91_RS23300 (4556) | 4556..5260 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ91_RS23305 (5454) | 5454..5840 | + | 387 | WP_063102497.1 | bleomycin binding protein | - |
| HUZ91_RS23310 (6160) | 6160..6552 | - | 393 | WP_000084745.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| HUZ91_RS23315 (7029) | 7029..8204 | + | 1176 | WP_002914189.1 | Efflux pump periplasmic linker BepF | VF |
| HUZ91_RS23320 (8228) | 8228..11380 | + | 3153 | WP_000347934.1 | Efflux pump membrane transporter BepE | VF |
| HUZ91_RS23325 (11450) | 11450..11929 | - | 480 | WP_000888203.1 | Rrf2 family transcriptional regulator | - |
| HUZ91_RS23330 (12031) | 12031..12735 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HUZ91_RS23335 (12826) | 12826..15180 | + | 2355 | Protein_13 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUZ91_RS23340 (15256) | 15256..16271 | - | 1016 | Protein_14 | IS3 family transposase ISEc36 | Transposase |
| HUZ91_RS23345 (16666) | 16666..17322 | + | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| HUZ91_RS23350 (17641) | 17641..18030 | - | 390 | WP_275090570.1 | recombinase family protein | - |
| HUZ91_RS23355 (18021) | 18021..18725 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HUZ91_RS23360 (18671) | 18671..20824 | - | 2154 | WP_239606307.1 | Outer membrane usher protein YehB | VF |
| HUZ91_RS23365 (20840) | 20840..21532 | - | 693 | WP_001223973.1 | putative fimbrial chaperone YehC | VF |
| HUZ91_RS23370 (21585) | 21585..22128 | - | 544 | Protein_20 | fimbrial protein | - |
| HUZ91_RS23380 (23354) | 23354..23623 | + | 270 | WP_001275013.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| HUZ91_RS23385 (23627) | 23627..24157 | + | 531 | WP_000348883.1 | GNAT family N-acetyltransferase | Toxin Detail |
| HUZ91_RS23390 (24158) | 24158..24375 | + | 218 | Protein_24 | transposase | - |
| HUZ91_RS23395 (24431) | 24431..24747 | - | 317 | Protein_25 | type II toxin-antitoxin system VapC family toxin | - |
| HUZ91_RS23400 (24744) | 24744..24974 | - | 231 | WP_001261274.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| HUZ91_RS23405 (24931) | 24931..25029 | + | 99 | Protein_27 | hypothetical protein | - |
| HUZ91_RS23410 (25447) | 25447..27711 | - | 2265 | WP_015060475.1 | UvrD-helicase domain-containing protein | - |
| HUZ91_RS23415 (27713) | 27713..28489 | - | 777 | WP_039052454.1 | hypothetical protein | - |
| HUZ91_RS23420 (29246) | 29246..30226 | + | 981 | WP_112037015.1 | IS5 family transposase ISKpn26 | Transposase |
| HUZ91_RS23425 (30820) | 30820..30978 | - | 159 | Protein_31 | replication initiation protein | - |
| HUZ91_RS23430 (33124) | 33124..33438 | - | 315 | WP_015060479.1 | hypothetical protein | - |
| HUZ91_RS23435 (33641) | 33641..34345 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ91_RS23440 (34413) | 34413..35357 | + | 945 | Protein_34 | IS110 family transposase IS5708 | Transposase |
| HUZ91_RS23445 (35765) | 35765..36118 | + | 354 | Protein_35 | RNA 3'-terminal phosphate cyclase | - |
| HUZ91_RS23450 (36161) | 36161..38866 | - | 2706 | WP_016240421.1 | HTH-type transcriptional regulator MalT | VF |
| HUZ91_RS23455 (39195) | 39195..39892 | + | 698 | WP_223419864.1 | IS1 family transposase IS1R | Transposase |
| HUZ91_RS23460 (39902) | 39902..40633 | + | 732 | WP_094336930.1 | peptidoglycan DD-metalloendopeptidase family protein | - |
| HUZ91_RS23465 (40667) | 40667..40864 | - | 198 | WP_000843496.1 | DUF2933 domain-containing protein | - |
| HUZ91_RS23470 (40905) | 40905..43382 | - | 2478 | WP_001398208.1 | Ag(+)-translocating P-type ATPase SilP | - |
| HUZ91_RS23475 (43479) | 43479..43919 | - | 441 | WP_000758221.1 | DUF411 domain-containing protein | - |
| HUZ91_RS23480 (44006) | 44006..47152 | - | 3147 | WP_000574035.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| HUZ91_RS23485 (47163) | 47163..48455 | - | 1293 | WP_080052003.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| HUZ91_RS23490 (48569) | 48569..48922 | - | 354 | WP_001246155.1 | cation efflux system protein CusF | - |
| HUZ91_RS23495 (48950) | 48950..50335 | - | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| HUZ91_RS23500 (50525) | 50525..51205 | + | 681 | WP_000697969.1 | Transcriptional regulatory protein CusR | VF |
| HUZ91_RS23505 (51198) | 51198..52673 | + | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| HUZ91_RS23510 (52924) | 52924..53355 | + | 432 | WP_000790483.1 | silver-binding protein SilE | - |
| HUZ91_RS23515 (53499) | 53499..53849 | + | 351 | WP_000694953.1 | DUF305 domain-containing protein | - |
| HUZ91_RS23520 (54237) | 54237..55145 | - | 909 | Protein_50 | HNH endonuclease | - |
| HUZ91_RS23525 (55782) | 55782..56756 | + | 975 | WP_001148756.1 | sensor domain-containing diguanylate cyclase | - |
| HUZ91_RS23530 (57324) | 57324..57674 | + | 351 | WP_004118279.1 | hypothetical protein | - |
| HUZ91_RS23535 (57725) | 57725..58468 | + | 744 | WP_000129823.1 | hypothetical protein | - |
| HUZ91_RS23540 (58465) | 58465..59241 | + | 777 | WP_239606311.1 | site-specific integrase | - |
| HUZ91_RS23545 (59299) | 59299..59556 | - | 258 | WP_000764642.1 | hypothetical protein | - |
| HUZ91_RS23550 (59685) | 59685..59789 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| HUZ91_RS23555 (60324) | 60324..61190 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| HUZ91_RS23560 (61511) | 61511..61780 | - | 270 | WP_000339857.1 | hypothetical protein | - |
| HUZ91_RS23565 (62195) | 62195..63400 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| HUZ91_RS23570 (63400) | 63400..64374 | + | 975 | WP_000064120.1 | ParB family protein | - |
| HUZ91_RS23575 (64456) | 64456..65163 | - | 708 | Protein_61 | translesion error-prone DNA polymerase V subunit UmuC | - |
| HUZ91_RS23580 (65606) | 65606..66574 | + | 969 | WP_162722054.1 | IS5 family transposase IS903B | Transposase |
| HUZ91_RS23585 (66714) | 66714..67100 | - | 387 | WP_001039464.1 | plasmid stabilization protein StbA | - |
| HUZ91_RS23590 (67175) | 67175..67879 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ91_RS23595 (67870) | 67870..68121 | + | 252 | WP_239606312.1 | DUF3330 domain-containing protein | - |
| HUZ91_RS23600 (68297) | 68297..68857 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| HUZ91_RS23605 (68861) | 68861..71827 | + | 2967 | WP_160456465.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUZ91_RS23610 (72060) | 72060..72467 | - | 408 | WP_034167712.1 | hypothetical protein | - |
| HUZ91_RS23615 (72532) | 72532..72726 | + | 195 | WP_161759552.1 | DUF2384 domain-containing protein | - |
| HUZ91_RS23620 (72925) | 72925..73140 | - | 216 | WP_034167711.1 | hypothetical protein | - |
| HUZ91_RS23625 (73575) | 73575..73784 | + | 210 | Protein_71 | hypothetical protein | - |
| HUZ91_RS23630 (73909) | 73909..74823 | - | 915 | Protein_72 | IS5 family transposase ISKpn26 | Transposase |
| HUZ91_RS23635 (75186) | 75186..76157 | - | 972 | WP_032482493.1 | IS91 family transposase ISAzo26 | Transposase |
| HUZ91_RS23640 (76560) | 76560..77192 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| HUZ91_RS23645 (77215) | 77215..77490 | + | 276 | WP_109023896.1 | hypothetical protein | - |
| HUZ91_RS23650 (77493) | 77493..78284 | - | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| HUZ91_RS23655 (78753) | 78753..78998 | - | 246 | WP_001354008.1 | GrpB family protein | - |
| HUZ91_RS23660 (79036) | 79036..79899 | - | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| HUZ91_RS23665 (80045) | 80045..80302 | - | 258 | Protein_79 | hypothetical protein | - |
| HUZ91_RS23670 (80357) | 80357..81061 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ91_RS23675 (81127) | 81127..81609 | + | 483 | Protein_81 | IS3 family transposase IS629 | Transposase |
| HUZ91_RS23680 (81652) | 81652..82470 | - | 819 | Protein_82 | IS30 family transposase IS30D | Transposase |
| HUZ91_RS23685 (82538) | 82538..83431 | + | 894 | Protein_83 | IS3 family transposase ISEhe3 | Transposase |
| HUZ91_RS23690 (83533) | 83533..83814 | + | 282 | WP_000639434.1 | hypothetical protein | - |
| HUZ91_RS23700 (84722) | 84722..86047 | + | 1326 | WP_021512928.1 | reactive chlorine resistance oxidoreductase RclA | - |
| HUZ91_RS23705 (86196) | 86196..86900 | - | 705 | WP_001505086.1 | IS6 family transposase IS26 | Transposase |
| HUZ91_RS23710 (86891) | 86891..87397 | + | 507 | WP_001505085.1 | hypothetical protein | - |
| HUZ91_RS23715 (87394) | 87394..88170 | + | 777 | Protein_89 | site-specific integrase | - |
| HUZ91_RS23720 (88322) | 88322..88597 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| HUZ91_RS23725 (88591) | 88591..89235 | - | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| HUZ91_RS23730 (89457) | 89457..90428 | + | 972 | WP_001103690.1 | plasmid segregation protein ParM | - |
| HUZ91_RS23735 (90433) | 90433..90825 | + | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| HUZ91_RS23740 (90830) | 90830..92101 | - | 1272 | WP_000457518.1 | Y-family DNA polymerase | - |
| HUZ91_RS23745 (92101) | 92101..92538 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| HUZ91_RS23750 (92535) | 92535..92783 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| HUZ91_RS23755 (93201) | 93201..94103 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| HUZ91_RS23760 (94100) | 94100..94411 | + | 312 | WP_011254640.1 | hypothetical protein | - |
| HUZ91_RS23765 (94488) | 94488..95171 | + | 684 | WP_000086185.1 | DNA methylase | - |
| HUZ91_RS23770 (95172) | 95172..95393 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| HUZ91_RS23775 (95323) | 95323..95841 | + | 519 | WP_123325260.1 | DUF1380 family protein | - |
| HUZ91_RS23780 (95892) | 95892..96668 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| HUZ91_RS23785 (96745) | 96745..97857 | + | 1113 | WP_001300563.1 | IS4 family transposase IS421 | Transposase |
| HUZ91_RS23790 (98434) | 98434..98859 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| HUZ91_RS23795 (98906) | 98906..99328 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| HUZ91_RS23800 (99325) | 99325..99516 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| HUZ91_RS23805 (99878) | 99878..100123 | + | 246 | WP_012372797.1 | hypothetical protein | - |
| HUZ91_RS23810 (100551) | 100551..100781 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| HUZ91_RS23815 (100833) | 100833..102194 | + | 1362 | WP_038999961.1 | DUF3560 domain-containing protein | - |
| HUZ91_RS23820 (102242) | 102242..102805 | + | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| HUZ91_RS23825 (102957) | 102957..103184 | + | 228 | WP_071961421.1 | hypothetical protein | - |
| HUZ91_RS23830 (103425) | 103425..103631 | + | 207 | WP_000275853.1 | hypothetical protein | - |
| HUZ91_RS23835 (103657) | 103657..104196 | + | 540 | WP_032332913.1 | single-stranded DNA-binding protein | - |
| HUZ91_RS23840 (104253) | 104253..104486 | + | 234 | WP_000005987.1 | DUF905 family protein | - |
| HUZ91_RS23845 (104551) | 104551..106509 | + | 1959 | WP_039000998.1 | ParB/RepB/Spo0J family partition protein | - |
| HUZ91_RS23850 (106564) | 106564..106998 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| HUZ91_RS23855 (106995) | 106995..107714 | + | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| HUZ91_RS23860 (107726) | 107726..107914 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - (107726) | 107726..107950 | + | 225 | NuclAT_0 | - | - |
| - (107726) | 107726..107950 | + | 225 | NuclAT_0 | - | - |
| - (107726) | 107726..107950 | + | 225 | NuclAT_0 | - | - |
| - (107726) | 107726..107950 | + | 225 | NuclAT_0 | - | - |
| HUZ91_RS23865 (107936) | 107936..108085 | + | 150 | Protein_119 | plasmid maintenance protein Mok | - |
| HUZ91_RS23870 (108027) | 108027..108152 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HUZ91_RS23875 (108372) | 108372..108602 | + | 231 | WP_001426396.1 | hypothetical protein | - |
| HUZ91_RS23880 (108600) | 108600..108773 | - | 174 | Protein_122 | hypothetical protein | - |
| HUZ91_RS23885 (108843) | 108843..109049 | + | 207 | WP_000547968.1 | hypothetical protein | - |
| HUZ91_RS23890 (109074) | 109074..109361 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| HUZ91_RS23895 (109484) | 109484..110305 | + | 822 | WP_239606300.1 | DUF932 domain-containing protein | - |
| HUZ91_RS23900 (110602) | 110602..111204 | - | 603 | WP_000243712.1 | hypothetical protein | VF |
| HUZ91_RS23905 (111525) | 111525..111908 | + | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| HUZ91_RS23910 (112095) | 112095..112784 | + | 690 | WP_039002187.1 | conjugal transfer transcriptional regulator TraJ | - |
| HUZ91_RS23915 (112877) | 112877..113278 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| HUZ91_RS23920 (113311) | 113311..113673 | + | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| HUZ91_RS23925 (113678) | 113678..113989 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| HUZ91_RS23930 (114011) | 114011..114577 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| HUZ91_RS23935 (114564) | 114564..115292 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| HUZ91_RS23940 (115292) | 115292..116719 | + | 1428 | WP_000146690.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| HUZ91_RS23945 (116709) | 116709..117296 | + | 588 | WP_000002772.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| HUZ91_RS23950 (117283) | 117283..117603 | + | 321 | WP_239606302.1 | conjugal transfer protein TrbD | - |
| HUZ91_RS23955 (117600) | 117600..118115 | + | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HUZ91_RS23960 (118250) | 118250..118471 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| HUZ91_RS23965 (118631) | 118631..121258 | + | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| HUZ91_RS23970 (121255) | 121255..121641 | + | 387 | WP_039002198.1 | type-F conjugative transfer system protein TrbI | - |
| HUZ91_RS23975 (121638) | 121638..122270 | + | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| HUZ91_RS23980 (122267) | 122267..123259 | + | 993 | WP_023148235.1 | conjugal transfer pilus assembly protein TraU | - |
| HUZ91_RS23985 (123268) | 123268..123906 | + | 639 | WP_000777691.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HUZ91_RS23990 (123903) | 123903..125711 | + | 1809 | WP_000821844.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HUZ91_RS23995 (125738) | 125738..125998 | + | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| HUZ91_RS24000 (125991) | 125991..126734 | + | 744 | WP_039002205.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HUZ91_RS24005 (126895) | 126895..127131 | + | 237 | WP_054377141.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HUZ91_RS24010 (127118) | 127118..127663 | + | 546 | WP_000052613.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HUZ91_RS24015 (127593) | 127593..127955 | + | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| HUZ91_RS24020 (127955) | 127955..129328 | + | 1374 | WP_170926237.1 | conjugal transfer pilus assembly protein TraH | - |
| HUZ91_RS24025 (129325) | 129325..132147 | + | 2823 | WP_001007048.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| HUZ91_RS24030 (132162) | 132162..132665 | + | 504 | WP_000605510.1 | hypothetical protein | - |
| HUZ91_RS24035 (132697) | 132697..133428 | + | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| HUZ91_RS24040 (133681) | 133681..135861 | + | 2181 | WP_063078088.1 | type IV conjugative transfer system coupling protein TraD | - |
| HUZ91_RS24045 (135861) | 135861..141131 | + | 5271 | WP_239606305.1 | Multifunctional conjugation protein TraI | Relaxase |
| HUZ91_RS24050 (141151) | 141151..141894 | + | 744 | WP_039002216.1 | conjugal transfer pilus acetylase TraX | - |
| HUZ91_RS24055 (141949) | 141949..142509 | + | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| HUZ91_RS24060 (142644) | 142644..142856 | + | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| - (143198) | 143198..143259 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (143198) | 143198..143259 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (143198) | 143198..143259 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (143198) | 143198..143259 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| HUZ91_RS24065 (143303) | 143303..143452 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| HUZ91_RS24070 (143720) | 143720..143977 | + | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| HUZ91_RS24075 (144080) | 144080..144263 | + | 184 | Protein_161 | plasmid copy control protein CopA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|