MGE detailed information
MGE type: Conjugative plasmid MGE length: 142890 bp
Accession: NZ_CP054941 Location: 1..142890 Organism: Escherichia coli strain MS6192 Replicon: plasmid pMS6192A-NDM
Accession: NZ_CP054941 Location: 1..142890 Organism: Escherichia coli strain MS6192 Replicon: plasmid pMS6192A-NDM
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MS6192_RS23590 () | 404..622 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| MS6192_RS23595 () | 624..929 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| MS6192_RS23600 () | 930..1736 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| MS6192_RS23605 () | 2510..3265 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| MS6192_RS23610 () | 3853..5019 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| MS6192_RS23615 () | 5019..5990 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| MS6192_RS23620 () | 6857..7759 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| MS6192_RS23625 () | 7763..8067 | + | 305 | Protein_7 | hypothetical protein | - |
| MS6192_RS23630 () | 8143..8826 | + | 684 | WP_000086185.1 | DNA methylase | - |
| MS6192_RS23635 () | 8827..9048 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| MS6192_RS23640 () | 9062..9496 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| MS6192_RS23645 () | 9547..10323 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| MS6192_RS23650 () | 10864..11166 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| MS6192_RS23655 () | 11213..11635 | + | 423 | WP_000271684.1 | DUF1380 family protein | - |
| MS6192_RS23660 () | 11632..11823 | + | 192 | WP_039021874.1 | hypothetical protein | - |
| MS6192_RS23665 () | 12858..13088 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| MS6192_RS23670 () | 13140..14501 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| MS6192_RS23675 () | 14549..15112 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| MS6192_RS23680 () | 15138..15362 | + | 225 | WP_016238251.1 | hypothetical protein | - |
| MS6192_RS23685 () | 16463..17032 | - | 570 | WP_089634947.1 | hypothetical protein | - |
| MS6192_RS23695 () | 18336..19094 | + | 759 | Protein_21 | site-specific integrase | - |
| MS6192_RS23700 () | 19252..20262 | + | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
| MS6192_RS23705 () | 20358..22484 | + | 2127 | WP_000253905.1 | alpha-galactosidase | - |
| MS6192_RS23710 () | 22547..23824 | + | 1278 | WP_001083369.1 | MFS transporter | - |
| MS6192_RS23715 () | 23824..25254 | + | 1431 | WP_000813680.1 | glycoside hydrolase family 32 protein | - |
| MS6192_RS23720 () | 25449..26843 | + | 1395 | WP_001037799.1 | carbohydrate porin | - |
| MS6192_RS23725 () | 27089..27193 | - | 105 | Protein_27 | thiosulfate reductase cytochrome B subunit | - |
| MS6192_RS23730 () | 27250..27943 | + | 694 | Protein_28 | IS1 family transposase IS1A | Transposase |
| MS6192_RS23735 () | 27959..28582 | + | 624 | WP_000912556.1 | potassium channel family protein | - |
| MS6192_RS23740 () | 28667..28918 | + | 252 | Protein_30 | iron-containing alcohol dehydrogenase | - |
| MS6192_RS23745 () | 29207..29524 | - | 318 | Protein_31 | IS110 family transposase | - |
| MS6192_RS23750 () | 29679..29784 | + | 106 | Protein_32 | plasmid SOS inhibition protein A | - |
| - () | 29753..29951 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 29753..29951 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 29753..29951 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 29753..29951 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| MS6192_RS23755 () | 30016..30174 | + | 159 | WP_001302184.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| MS6192_RS23760 () | 30842..31048 | + | 207 | WP_000275854.1 | hypothetical protein | - |
| MS6192_RS23765 () | 31073..31360 | + | 288 | WP_000107242.1 | hypothetical protein | - |
| MS6192_RS23770 () | 31479..32300 | + | 822 | WP_001234465.1 | DUF945 domain-containing protein | - |
| MS6192_RS23775 () | 32596..33168 | - | 573 | WP_000949660.1 | hypothetical protein | VF |
| MS6192_RS23780 () | 33538..33921 | + | 384 | WP_001063020.1 | relaxosome protein TraM | - |
| MS6192_RS23785 () | 34112..34759 | + | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| MS6192_RS23790 () | 34895..35110 | + | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| MS6192_RS23795 () | 35153..35518 | + | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| MS6192_RS23800 () | 35533..35844 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| MS6192_RS23805 () | 35866..36432 | + | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| MS6192_RS23810 () | 36419..36592 | + | 174 | Protein_44 | traK family protein | - |
| MS6192_RS23815 () | 36593..37003 | + | 411 | Protein_45 | conjugal transfer protein TraP | - |
| MS6192_RS23820 () | 36990..37127 | + | 138 | WP_001553834.1 | conjugal transfer protein TrbD | - |
| MS6192_RS23825 () | 37149..37310 | + | 162 | WP_000741714.1 | conjugal transfer protein TrbD | - |
| MS6192_RS23830 () | 37303..37554 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| MS6192_RS23835 () | 37551..38066 | + | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
| MS6192_RS23840 () | 38201..38422 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| MS6192_RS23845 () | 38582..41209 | + | 2628 | WP_001064264.1 | type IV secretion system protein TraC | - |
| MS6192_RS23850 () | 41206..41592 | + | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| MS6192_RS23855 () | 41589..42221 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| MS6192_RS23860 () | 42218..42376 | + | 159 | Protein_54 | Multifunctional conjugation protein TraI | Relaxase |
| MS6192_RS23865 () | 43536..44282 | + | 747 | WP_000205701.1 | conjugal transfer pilus acetylase TraX | - |
| MS6192_RS23870 () | 44337..44897 | + | 561 | WP_000139363.1 | fertility inhibition protein FinO | - |
| MS6192_RS23875 () | 45030..45242 | + | 213 | WP_005012601.1 | hypothetical protein | - |
| MS6192_RS23880 () | 45543..46245 | - | 703 | Protein_58 | IS1 family transposase IS1S | Transposase |
| MS6192_RS23885 () | 46346..46528 | + | 183 | WP_000968309.1 | hypothetical protein | - |
| - () | 46667..46728 | - | 62 | NuclAT_1 | - | - |
| - () | 46667..46728 | - | 62 | NuclAT_1 | - | - |
| - () | 46667..46728 | - | 62 | NuclAT_1 | - | - |
| - () | 46667..46728 | - | 62 | NuclAT_1 | - | - |
| MS6192_RS23890 () | 46715..46921 | + | 207 | WP_015387399.1 | type I toxin-antitoxin system Hok family toxin | - |
| MS6192_RS23895 () | 47205..47462 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| MS6192_RS23900 () | 47698..47772 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| MS6192_RS23905 () | 47765..48211 | + | 447 | Protein_63 | incFII family plasmid replication initiator RepA | - |
| MS6192_RS23910 () | 48157..48639 | - | 483 | Protein_64 | VENN motif pre-toxin domain-containing protein | - |
| MS6192_RS23915 () | 49532..50752 | + | 1221 | WP_000410951.1 | arginine deiminase | - |
| MS6192_RS23920 () | 50763..51674 | + | 912 | WP_000440183.1 | carbamate kinase | - |
| MS6192_RS23925 () | 51759..52763 | + | 1005 | WP_000154544.1 | Ornithine carbamoyltransferase | VF |
| MS6192_RS23930 () | 52811..54214 | + | 1404 | WP_000514417.1 | YfcC family protein | - |
| MS6192_RS23935 () | 54295..54774 | + | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| MS6192_RS23940 () | 54838..55179 | - | 342 | Protein_70 | IS66 family transposase IS682 | Transposase |
| MS6192_RS23945 () | 55131..55352 | - | 222 | WP_000080217.1 | hypothetical protein | - |
| MS6192_RS23950 () | 55383..55733 | - | 351 | WP_000624725.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| MS6192_RS23955 () | 55730..56092 | - | 363 | WP_059330006.1 | IS66 family transposase ISEc23 | Transposase |
| MS6192_RS23960 () | 56201..56894 | - | 694 | Protein_74 | IS1 family transposase IS1A | Transposase |
| MS6192_RS23965 () | 56927..57505 | + | 579 | WP_032147503.1 | DUF2726 domain-containing protein | - |
| MS6192_RS23970 () | 57918..58271 | - | 354 | WP_000005489.1 | hypothetical protein | - |
| MS6192_RS23975 () | 58743..59765 | - | 1023 | WP_000156883.1 | IS110 family transposase ISSm1 | Transposase |
| MS6192_RS23980 () | 60170..60427 | + | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| MS6192_RS23985 () | 60663..60737 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| MS6192_RS23990 () | 60730..61587 | + | 858 | WP_000130948.1 | incFII family plasmid replication initiator RepA | - |
| MS6192_RS23995 () | 62288..62428 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| MS6192_RS24000 () | 62526..63179 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| MS6192_RS24005 () | 63272..63529 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| MS6192_RS24010 () | 63462..63863 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| MS6192_RS24015 () | 64000..65085 | - | 1086 | Protein_85 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| MS6192_RS24020 () | 65144..65848 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MS6192_RS24025 () | 65992..66546 | + | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| MS6192_RS24030 () | 66677..67507 | + | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| MS6192_RS24035 () | 67645..68085 | + | 441 | Protein_89 | CatB-related O-acetyltransferase | - |
| MS6192_RS24040 () | 68139..68843 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MS6192_RS24045 () | 68950..69810 | + | 861 | WP_000557452.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| MS6192_RS24050 () | 69823..70365 | + | 543 | WP_002063889.1 | AAA family ATPase | - |
| MS6192_RS24055 () | 70457..70645 | + | 189 | Protein_93 | IS3 family transposase ISKpn11 | Transposase |
| MS6192_RS24060 () | 70699..71403 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| MS6192_RS24065 () | 71568..71861 | + | 294 | Protein_95 | IS30 family transposase | - |
| MS6192_RS24070 () | 71962..72774 | + | 813 | WP_004201164.1 | Metallo-beta-lactamase type 2 | ARG |
| MS6192_RS24075 () | 72778..73143 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| MS6192_RS24080 () | 73148..73786 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| MS6192_RS24085 () | 73797..74828 | - | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| MS6192_RS24090 () | 75141..76682 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| MS6192_RS24095 () | 77087..77926 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| MS6192_RS24100 () | 77920..78267 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| MS6192_RS24105 () | 78431..79222 | - | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| MS6192_RS24110 () | 79228..79518 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| MS6192_RS24115 () | 79630..80127 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| MS6192_RS24120 () | 80272..81285 | + | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| MS6192_RS24125 () | 81488..81838 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| MS6192_RS24130 () | 81964..82524 | + | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| MS6192_RS24135 () | 82527..85493 | + | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| MS6192_RS24140 () | 85560..85937 | + | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| MS6192_RS24145 () | 86063..86760 | - | 698 | Protein_111 | IS1 family transposase IS1X2 | Transposase |
| MS6192_RS24150 () | 87223..87381 | + | 159 | WP_000449408.1 | DsbA family protein | - |
| MS6192_RS24155 () | 87371..87877 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| MS6192_RS24160 () | 88060..88875 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| MS6192_RS24165 () | 89222..91108 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| MS6192_RS24170 () | 91149..91676 | + | 528 | WP_000178050.1 | iron transporter | - |
| MS6192_RS24175 () | 91780..93159 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| MS6192_RS24180 () | 93162..94445 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| MS6192_RS24185 () | 94435..95565 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| MS6192_RS24190 () | 95570..96265 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| MS6192_RS24195 () | 96252..96737 | + | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| MS6192_RS24200 () | 96762..97247 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| MS6192_RS24205 () | 97369..97899 | + | 531 | Protein_123 | histidine-type phosphatase | - |
| MS6192_RS24210 () | 97957..98661 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| MS6192_RS24215 () | 98686..99882 | + | 1197 | Protein_125 | IS3 family transposase | - |
| MS6192_RS24220 () | 99904..100137 | + | 234 | Protein_126 | Tn3 family transposase ISPsy39 | Transposase |
| MS6192_RS24225 () | 100214..100522 | + | 309 | Protein_127 | IS4 family transposase ISEc13 | Transposase |
| MS6192_RS24230 () | 100581..101891 | - | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| MS6192_RS24235 () | 101884..102957 | - | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| MS6192_RS24240 () | 102963..103787 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| MS6192_RS24245 () | 103798..104685 | - | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| MS6192_RS24250 () | 104675..105553 | - | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| MS6192_RS24255 () | 105684..106124 | - | 441 | Protein_133 | zinc-binding dehydrogenase | - |
| MS6192_RS24260 () | 106098..106292 | + | 195 | WP_000796505.1 | hypothetical protein | - |
| MS6192_RS24265 () | 106525..107415 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| MS6192_RS24270 () | 107440..107820 | + | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| MS6192_RS24275 () | 107853..108818 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| MS6192_RS24280 () | 108864..109616 | - | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| MS6192_RS24285 () | 110221..110505 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| MS6192_RS24290 () | 110505..110780 | + | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| MS6192_RS24295 () | 110886..111179 | + | 294 | WP_001105060.1 | hypothetical protein | - |
| MS6192_RS24300 () | 111214..111342 | - | 129 | Protein_142 | IS481 family transposase | - |
| MS6192_RS24305 () | 111375..112544 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| MS6192_RS24310 () | 113037..113344 | + | 308 | Protein_144 | type II toxin-antitoxin system ParD family antitoxin | - |
| MS6192_RS24315 () | 113687..113869 | + | 183 | WP_042065278.1 | hypothetical protein | - |
| MS6192_RS24320 () | 113990..114730 | + | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| MS6192_RS24325 () | 115015..115992 | - | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| MS6192_RS24330 () | 117113..117508 | + | 396 | WP_175188304.1 | hypothetical protein | - |
| MS6192_RS24335 () | 117995..118692 | + | 698 | Protein_149 | IS1 family transposase IS1R | Transposase |
| MS6192_RS24340 () | 118708..119037 | + | 330 | Protein_150 | TOBE domain-containing protein | - |
| MS6192_RS24345 () | 119146..120078 | - | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| MS6192_RS24350 () | 120065..121468 | - | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| MS6192_RS24355 () | 121676..122692 | + | 1017 | WP_012372828.1 | IS5 family transposase IS5D | Transposase |
| MS6192_RS24360 () | 122920..123237 | + | 318 | WP_001513659.1 | hypothetical protein | - |
| MS6192_RS24365 () | 123187..123600 | - | 414 | Protein_155 | IS3 family transposase ISLad1 | Transposase |
| MS6192_RS24370 () | 123524..123883 | - | 360 | WP_001513660.1 | hypothetical protein | - |
| MS6192_RS24375 () | 123911..124090 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| MS6192_RS24380 () | 124095..124475 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| MS6192_RS24385 () | 124475..124696 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| MS6192_RS24390 () | 124879..126435 | + | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| MS6192_RS24395 () | 126432..127715 | + | 1284 | WP_001553855.1 | restriction endonuclease subunit S | - |
| MS6192_RS24400 () | 127837..130953 | + | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| MS6192_RS24405 () | 131167..131864 | + | 698 | Protein_163 | IS1 family transposase IS1G | Transposase |
| MS6192_RS24410 () | 132001..132933 | - | 933 | WP_000991832.1 | hypothetical protein | - |
| MS6192_RS24415 () | 132937..133932 | - | 996 | WP_000246636.1 | hypothetical protein | - |
| MS6192_RS24420 () | 134397..136535 | + | 2139 | WP_000350635.1 | AAA family ATPase | - |
| MS6192_RS24425 () | 136697..137113 | - | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| MS6192_RS24430 () | 137110..137340 | - | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| MS6192_RS24435 () | 137647..140766 | + | 3120 | WP_001553851.1 | hypothetical protein | - |
| MS6192_RS24440 () | 141029..142162 | + | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| MS6192_RS24445 () | 142182..142466 | + | 285 | WP_000642771.1 | hypothetical protein | - |
| MS6192_RS24450 () | 142463..142660 | - | 198 | WP_000215657.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|