MGE detailed information
MGE type: Conjugative plasmid MGE length: 135461 bp
Accession: NZ_CP054228 Location: 1..135461 Organism: Escherichia coli strain EcPF15 Replicon: plasmid p1
Accession: NZ_CP054228 Location: 1..135461 Organism: Escherichia coli strain EcPF15 Replicon: plasmid p1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HR073_RS22570 () | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| HR073_RS22575 () | 1263..2003 | - | 741 | WP_176323697.1 | tyrosine-type recombinase/integrase | - |
| HR073_RS22580 () | 2124..2273 | - | 150 | WP_176323727.1 | transcriptional regulator | - |
| HR073_RS22585 () | 3201..3521 | + | 321 | WP_170981805.1 | Major pilu subunit operon regulatory protein PapB | VF |
| HR073_RS22590 () | 3564..4088 | + | 525 | WP_113456391.1 | Pap fimbrial major pilin protein | VF |
| HR073_RS22595 () | 4169..4753 | + | 585 | WP_176323698.1 | PAP fimbrial minor pilin protein | VF |
| HR073_RS22600 () | 4900..7410 | + | 2511 | WP_176323728.1 | Outer membrane usher protein PapC | VF |
| HR073_RS22605 () | 7539..8270 | + | 732 | WP_176323699.1 | Chaperone protein PapD | VF |
| HR073_RS22610 () | 8307..8894 | + | 588 | WP_176323700.1 | hypothetical protein | VF |
| HR073_RS22615 () | 8921..9457 | + | 537 | WP_176323729.1 | Fimbrial adapter PapK | VF |
| HR073_RS22620 () | 9477..9998 | + | 522 | WP_176323701.1 | Fimbrial protein PapE | VF |
| HR073_RS22625 () | 10192..10728 | + | 537 | WP_176323702.1 | Fimbrial adapter PapF | VF |
| HR073_RS22630 () | 10893..11873 | + | 981 | WP_176323703.1 | hypothetical protein | - |
| HR073_RS22635 () | 12722..13432 | + | 711 | WP_176323704.1 | EAL domain-containing protein | - |
| HR073_RS22640 () | 13509..17417 | + | 3909 | WP_176323705.1 | Temperature-sensitive hemagglutinin tsh autotransporter | VF |
| HR073_RS22645 () | 17593..18099 | + | 507 | WP_024187543.1 | RTX-I toxin-activating lysine-acyltransferase ApxIC | VF |
| HR073_RS22650 () | 18089..20689 | + | 2601 | WP_021533272.1 | Leukotoxin | VF |
| HR073_RS22655 () | 20744..22855 | + | 2112 | WP_113456398.1 | Leukotoxin export ATP-binding protein LtxB | VF |
| HR073_RS22660 () | 22869..24281 | + | 1413 | WP_021533274.1 | Leukotoxin export protein LtxD | VF |
| HR073_RS22665 () | 24647..24952 | - | 306 | WP_113456399.1 | Cyclic di-GMP phosphodiesterase PdeL | VF |
| HR073_RS22670 () | 25265..25455 | + | 191 | Protein_20 | ATP-binding protein | - |
| HR073_RS22675 () | 25519..25584 | + | 66 | Protein_21 | hypothetical protein | - |
| HR073_RS22680 () | 26508..27167 | + | 660 | WP_176323706.1 | spore coat protein U domain-containing protein | - |
| HR073_RS22685 () | 27198..27908 | + | 711 | WP_137460822.1 | fimbria/pilus periplasmic chaperone | - |
| HR073_RS22690 () | 27877..30267 | + | 2391 | WP_176323707.1 | fimbria/pilus outer membrane usher protein | - |
| HR073_RS22695 () | 30279..30785 | + | 507 | WP_113456403.1 | hypothetical protein | - |
| HR073_RS22700 () | 30950..31258 | + | 309 | Protein_26 | hypothetical protein | - |
| HR073_RS22715 () | 34294..35196 | - | 903 | WP_176323709.1 | hypothetical protein | VF |
| HR073_RS22720 () | 35286..36395 | - | 1110 | WP_021532999.1 | SDR family oxidoreductase | - |
| HR073_RS22725 () | 36934..37884 | + | 951 | WP_021532998.1 | Protease 7 | VF |
| HR073_RS22730 () | 37996..39183 | + | 1188 | WP_001523410.1 | efflux RND transporter periplasmic adaptor subunit | - |
| HR073_RS22735 () | 39180..41120 | + | 1941 | WP_113456404.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| HR073_RS22740 () | 41124..42494 | + | 1371 | WP_032144654.1 | Toxin and drug export protein A | VF |
| HR073_RS22745 () | 42940..43422 | + | 483 | WP_033555928.1 | hypothetical protein | - |
| HR073_RS22750 () | 43557..44042 | - | 486 | Protein_36 | ISNCY family transposase ISLad2 | Transposase |
| HR073_RS22755 () | 44348..44497 | - | 150 | Protein_37 | IS3 family transposase IS2 | Transposase |
| HR073_RS22760 () | 44675..45868 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| HR073_RS22765 () | 47627..47920 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| HR073_RS22770 () | 47978..48153 | - | 176 | Protein_40 | lysis protein | - |
| HR073_RS22775 () | 48731..49830 | + | 1100 | Protein_41 | IS481 family transposase ISKpn28 | Transposase |
| HR073_RS22780 () | 51066..52181 | + | 1116 | WP_021532994.1 | Elloramycin glycosyltransferase ElmGT | VF |
| HR073_RS22785 () | 52321..55980 | + | 3660 | WP_001442133.1 | Multidrug efflux ATP-binding/permease protein | VF |
| HR073_RS22790 () | 56084..57313 | + | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| HR073_RS22795 () | 57398..58354 | + | 957 | WP_000271277.1 | Ferri-bacillibactin esterase BesA | VF |
| HR073_RS22800 () | 58399..60576 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| HR073_RS22805 () | 61352..62580 | + | 1229 | WP_176323710.1 | IS3 family transposase IS2 | Transposase |
| HR073_RS22810 () | 62767..63801 | - | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| HR073_RS22815 () | 64361..64669 | - | 309 | WP_176323711.1 | hypothetical protein | - |
| HR073_RS22820 () | 64768..64950 | - | 183 | WP_000969988.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| HR073_RS22825 () | 64947..65144 | - | 198 | WP_137504090.1 | toxin-antitoxin system protein | Antitoxin Detail |
| HR073_RS22830 () | 65826..67100 | + | 1275 | WP_176323712.1 | HlyD family secretion protein | - |
| HR073_RS22835 () | 67075..69189 | + | 2115 | WP_176323713.1 | peptidase domain-containing ABC transporter | - |
| HR073_RS22840 () | 69359..69670 | - | 312 | WP_001259758.1 | colicin V | - |
| HR073_RS22845 () | 69648..69884 | - | 237 | WP_001323890.1 | colicin V immunity protein | - |
| HR073_RS22850 () | 70051..70822 | + | 772 | Protein_56 | Gfo/Idh/MocA family oxidoreductase | - |
| HR073_RS22855 () | 70824..71093 | + | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| HR073_RS22860 () | 71090..71356 | + | 267 | WP_001017350.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| HR073_RS22865 () | 71412..71864 | - | 453 | WP_000670963.1 | N-acetyltransferase | - |
| HR073_RS22870 () | 72138..73351 | + | 1214 | WP_085947772.1 | IS3 family transposase ISCfr6 | Transposase |
| HR073_RS22875 () | 73358..74086 | - | 729 | Protein_61 | 3'-5' exonuclease | - |
| HR073_RS22880 () | 74132..74413 | - | 282 | WP_000969996.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| HR073_RS22885 () | 74410..74679 | - | 270 | WP_000079948.1 | hypothetical protein | Antitoxin Detail |
| HR073_RS22890 () | 75594..76451 | - | 858 | WP_176323714.1 | incFII family plasmid replication initiator RepA | - |
| HR073_RS22895 () | 76444..76518 | - | 75 | WP_097378006.1 | RepA leader peptide Tap | - |
| HR073_RS22900 () | 76752..77009 | - | 258 | WP_000083826.1 | replication regulatory protein RepA | - |
| HR073_RS22905 () | 77172..77330 | - | 159 | WP_172428062.1 | hypothetical protein | - |
| HR073_RS22910 () | 77468..78028 | - | 561 | WP_176323715.1 | fertility inhibition protein FinO | - |
| HR073_RS22915 () | 78083..78823 | - | 741 | WP_176323716.1 | conjugal transfer pilus acetylase TraX | - |
| HR073_RS22920 () | 78843..84113 | - | 5271 | WP_176323717.1 | Multifunctional conjugation protein TraI | Relaxase |
| HR073_RS22925 () | 84195..84422 | + | 228 | WP_161574083.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| HR073_RS22930 () | 84422..84820 | + | 399 | WP_097377987.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| HR073_RS22935 () | 84829..86991 | - | 2163 | WP_176323718.1 | type IV conjugative transfer system coupling protein TraD | - |
| HR073_RS22940 () | 87306..87999 | - | 694 | Protein_74 | hypothetical protein | - |
| HR073_RS22945 () | 88211..88519 | + | 309 | WP_097377989.1 | heavy metal-binding domain-containing protein | - |
| HR073_RS22950 () | 88522..91341 | - | 2820 | WP_176323719.1 | conjugal transfer mating pair stabilization protein TraG | - |
| HR073_RS22955 () | 91338..92711 | - | 1374 | WP_021553026.1 | conjugal transfer protein TraH | - |
| HR073_RS22960 () | 92711..93124 | - | 414 | WP_176323720.1 | F-type conjugal transfer protein TrbF | - |
| HR073_RS22965 () | 93078..93419 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| HR073_RS22970 () | 93349..93894 | - | 546 | WP_000059850.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HR073_RS22975 () | 93881..94165 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HR073_RS22980 () | 94246..94560 | + | 315 | WP_000415566.1 | protein ArtA | - |
| HR073_RS22985 () | 94562..94909 | - | 348 | WP_097377995.1 | conjugal transfer protein TrbA | - |
| HR073_RS22990 () | 94925..95668 | - | 744 | WP_176323721.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HR073_RS22995 () | 95661..95918 | - | 258 | WP_123020387.1 | conjugal transfer protein TrbE | - |
| HR073_RS23000 () | 95945..97753 | - | 1809 | WP_000821847.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HR073_RS23005 () | 97750..98388 | - | 639 | WP_000777695.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HR073_RS23010 () | 98397..98807 | - | 411 | Protein_88 | conjugal transfer pilus assembly protein TraU | - |
| HR073_RS23020 () | 100069..100650 | - | 582 | Protein_90 | conjugal transfer pilus assembly protein TraU | - |
| HR073_RS23025 () | 100647..101279 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| HR073_RS23030 () | 101276..101662 | - | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| HR073_RS23035 () | 101659..104286 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| HR073_RS23040 () | 104446..104667 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| HR073_RS23045 () | 104802..105317 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HR073_RS23050 () | 105314..105565 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| HR073_RS23055 () | 105558..105911 | - | 354 | WP_071594066.1 | conjugal transfer protein TrbD | - |
| HR073_RS23060 () | 105865..106455 | - | 591 | WP_000002787.1 | conjugal transfer protein TraP | - |
| HR073_RS23065 () | 106445..107872 | - | 1428 | WP_000146676.1 | conjugal transfer protein TraB | - |
| HR073_RS23070 () | 107872..108576 | - | 705 | WP_148713163.1 | type-F conjugative transfer system secretin TraK | - |
| HR073_RS23075 () | 108587..109153 | - | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| HR073_RS23080 () | 109175..109486 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| HR073_RS23085 () | 109501..109866 | - | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| HR073_RS23090 () | 109909..110124 | - | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| HR073_RS23095 () | 110260..110907 | - | 648 | WP_176323722.1 | conjugal transfer transcriptional regulator TraJ | - |
| HR073_RS23100 () | 111098..111481 | - | 384 | WP_001063020.1 | relaxosome protein TraM | - |
| HR073_RS23105 () | 111833..112423 | + | 591 | WP_001375132.1 | hypothetical protein | VF |
| HR073_RS23110 () | 112718..113539 | - | 822 | WP_176323730.1 | DUF945 domain-containing protein | - |
| HR073_RS23115 () | 113658..113945 | - | 288 | WP_176323723.1 | hypothetical protein | - |
| HR073_RS23120 () | 114101..114460 | + | 360 | Protein_110 | hypothetical protein | - |
| HR073_RS23125 () | 114697..114855 | - | 159 | WP_001302184.1 | type I toxin-antitoxin system Hok family toxin | - |
| - () | 114920..115118 | - | 199 | NuclAT_0 | - | - |
| - () | 114920..115118 | - | 199 | NuclAT_0 | - | - |
| - () | 114920..115118 | - | 199 | NuclAT_0 | - | - |
| - () | 114920..115118 | - | 199 | NuclAT_0 | - | - |
| HR073_RS23130 () | 115130..115849 | - | 720 | WP_000116348.1 | plasmid SOS inhibition protein A | - |
| HR073_RS23135 () | 115846..116280 | - | 435 | WP_000845928.1 | conjugation system SOS inhibitor PsiB | - |
| HR073_RS23140 () | 116335..118293 | - | 1959 | WP_029487628.1 | ParB/RepB/Spo0J family partition protein | - |
| HR073_RS23145 () | 118359..118592 | - | 234 | WP_176323724.1 | DUF905 family protein | - |
| HR073_RS23150 () | 118649..119188 | - | 540 | WP_000290801.1 | single-stranded DNA-binding protein | - |
| HR073_RS23155 () | 119991..120182 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| HR073_RS23160 () | 120179..120601 | - | 423 | WP_000271685.1 | DUF1380 family protein | - |
| HR073_RS23165 () | 120648..120950 | - | 303 | WP_072095193.1 | antirestriction protein | - |
| HR073_RS23170 () | 121487..122263 | - | 777 | WP_176323725.1 | hypothetical protein | - |
| HR073_RS23175 () | 122309..122863 | - | 555 | WP_001358893.1 | DUF1380 family protein | - |
| HR073_RS23180 () | 122757..122978 | - | 222 | WP_001104904.1 | hypothetical protein | - |
| HR073_RS23185 () | 122979..123662 | - | 684 | WP_000085939.1 | DNA methylase | - |
| HR073_RS23190 () | 123739..124044 | - | 306 | WP_010892536.1 | hypothetical protein | - |
| HR073_RS23195 () | 124048..124949 | - | 902 | Protein_125 | DUF1281 domain-containing protein | - |
| HR073_RS23200 () | 125773..126744 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HR073_RS23205 () | 126744..127910 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| HR073_RS23210 () | 128498..129142 | - | 645 | WP_001477618.1 | replication initiation protein RepE | - |
| HR073_RS23215 () | 129189..129995 | - | 807 | WP_024243979.1 | site-specific integrase | - |
| HR073_RS23220 () | 129996..130301 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| HR073_RS23225 () | 130303..130521 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| HR073_RS23230 () | 130989..131672 | + | 684 | WP_010891291.1 | DNA-binding protein | - |
| HR073_RS23235 () | 131669..132289 | + | 621 | WP_001248529.1 | hypothetical protein | - |
| HR073_RS23240 () | 132286..133074 | + | 789 | WP_176323726.1 | DUF2971 domain-containing protein | - |
| HR073_RS23245 () | 133110..133850 | + | 741 | WP_000933099.1 | abortive infection family protein | - |
| HR073_RS23250 () | 134009..134674 | - | 666 | WP_053265868.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|