MGE detailed information
MGE type: Conjugative plasmid MGE length: 158248 bp
Accession: NZ_CP047601 Location: 1..158248 Organism: Escherichia coli O84:H7 strain Trh52 Replicon: plasmid pTrh52_1
Accession: NZ_CP047601 Location: 1..158248 Organism: Escherichia coli O84:H7 strain Trh52 Replicon: plasmid pTrh52_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GUK18_RS22930 () | 1..978 | + | 978 | WP_001309253.1 | RepB family plasmid replication initiator protein | - |
| GUK18_RS22935 () | 1221..1961 | - | 741 | WP_021576052.1 | tyrosine-type recombinase/integrase | - |
| GUK18_RS22940 () | 3182..3460 | + | 279 | WP_001523382.1 | Major pilu subunit operon regulatory protein PapB | VF |
| GUK18_RS22945 () | 3515..4042 | + | 528 | WP_021572440.1 | Pap fimbrial major pilin protein | VF |
| GUK18_RS22950 () | 4123..4707 | + | 585 | WP_024244218.1 | PAP fimbrial minor pilin protein | VF |
| GUK18_RS22955 () | 4843..7353 | + | 2511 | WP_158666800.1 | Outer membrane usher protein PapC | VF |
| GUK18_RS22960 () | 7482..8213 | + | 732 | WP_021572443.1 | Chaperone protein PapD | VF |
| GUK18_RS22965 () | 8249..8836 | + | 588 | WP_021572444.1 | hypothetical protein | VF |
| GUK18_RS22970 () | 8854..9402 | + | 549 | WP_104934200.1 | Fimbrial adapter PapK | VF |
| GUK18_RS22975 () | 9422..9943 | + | 522 | WP_021572446.1 | Fimbrial protein PapE | VF |
| GUK18_RS22980 () | 9966..10526 | + | 561 | WP_021572447.1 | Fimbrial adapter PapF | VF |
| GUK18_RS22985 () | 10616..11596 | + | 981 | WP_104934201.1 | hypothetical protein | - |
| GUK18_RS22990 () | 11857..12680 | + | 824 | Protein_12 | polysaccharide deacetylase family protein | - |
| GUK18_RS22995 () | 12683..13321 | + | 639 | WP_064733215.1 | EAL domain-containing protein | - |
| GUK18_RS23000 () | 13416..17324 | + | 3909 | WP_021572451.1 | Temperature-sensitive hemagglutinin tsh autotransporter | VF |
| GUK18_RS23005 () | 17493..18002 | + | 510 | WP_021572452.1 | Leukotoxin-activating lysine-acyltransferase LtxC | VF |
| GUK18_RS23010 () | 17989..20589 | + | 2601 | WP_021572453.1 | Leukotoxin | VF |
| GUK18_RS23015 () | 20649..22760 | + | 2112 | WP_021572454.1 | Leukotoxin export ATP-binding protein LtxB | VF |
| GUK18_RS23020 () | 22774..24186 | + | 1413 | WP_001523401.1 | Leukotoxin export protein LtxD | VF |
| GUK18_RS23025 () | 25113..25652 | + | 540 | WP_021572455.1 | chorismate mutase | - |
| GUK18_RS23030 () | 26335..27237 | - | 903 | WP_024193543.1 | hypothetical protein | VF |
| GUK18_RS23035 () | 27327..28436 | - | 1110 | WP_001523408.1 | SDR family oxidoreductase | - |
| GUK18_RS23040 () | 28976..29926 | + | 951 | WP_104934202.1 | Protease 7 | VF |
| GUK18_RS23045 () | 30038..31225 | + | 1188 | WP_001523410.1 | efflux RND transporter periplasmic adaptor subunit | - |
| GUK18_RS23050 () | 31222..33162 | + | 1941 | WP_001523412.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| GUK18_RS23055 () | 33166..34536 | + | 1371 | WP_032144220.1 | Toxin and drug export protein A | VF |
| GUK18_RS23060 () | 35063..35649 | - | 587 | Protein_26 | ISNCY family transposase | - |
| GUK18_RS23065 () | 36258..37040 | - | 783 | WP_011076463.1 | IS21 family transposase IS100kyp | Transposase |
| GUK18_RS23070 () | 37037..38059 | - | 1023 | WP_104934203.1 | IS21 family transposase IS100kyp | Transposase |
| GUK18_RS23075 () | 38181..39471 | - | 1291 | Protein_29 | ISNCY family transposase | - |
| GUK18_RS23080 () | 39764..39913 | - | 150 | Protein_30 | IS3 family transposase IS2 | Transposase |
| GUK18_RS23085 () | 40091..41284 | - | 1194 | WP_000450492.1 | GTP-binding protein | - |
| GUK18_RS23090 () | 43045..43338 | + | 294 | WP_021572460.1 | increased serum survival lipoprotein Iss | - |
| GUK18_RS23095 () | 43396..43595 | - | 200 | Protein_33 | lysis protein | - |
| GUK18_RS23100 () | 44198..44824 | + | 627 | Protein_34 | helix-turn-helix domain-containing protein | - |
| GUK18_RS23105 () | 46008..47123 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| GUK18_RS23110 () | 47263..50922 | + | 3660 | WP_021572462.1 | Multidrug efflux ATP-binding/permease protein | VF |
| GUK18_RS23115 () | 51026..52255 | + | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| GUK18_RS23120 () | 52340..53296 | + | 957 | WP_000271277.1 | Ferri-bacillibactin esterase BesA | VF |
| GUK18_RS23125 () | 53341..55518 | - | 2178 | WP_001259003.1 | Ferric enterobactin receptor | VF |
| GUK18_RS23130 () | 55822..56082 | - | 261 | WP_000076221.1 | hypothetical protein | - |
| GUK18_RS23135 () | 56505..56728 | + | 224 | Protein_41 | hypothetical protein | - |
| GUK18_RS23140 () | 56814..57220 | - | 407 | Protein_42 | IS3 family transposase ISEc16 | Transposase |
| GUK18_RS23145 () | 57543..59027 | - | 1485 | WP_021541660.1 | alpha/beta hydrolase | - |
| GUK18_RS23150 () | 59212..60162 | - | 951 | WP_203164490.1 | Protease 7 | VF |
| GUK18_RS23155 () | 60550..60855 | - | 306 | WP_024188660.1 | hypothetical protein | - |
| GUK18_RS23160 () | 60907..62091 | + | 1185 | Protein_46 | IS91 family transposase ISEc37 | Transposase |
| GUK18_RS23165 () | 62277..62540 | - | 264 | Protein_47 | IS200-IS605 family transposase IS609 | Transposase |
| GUK18_RS23170 () | 62695..62967 | - | 273 | WP_016233085.1 | hypothetical protein | - |
| GUK18_RS23175 () | 63366..63599 | + | 234 | WP_004132711.1 | hypothetical protein | - |
| GUK18_RS23180 () | 63619..72201 | - | 8583 | WP_104934205.1 | Cyclic beta-(1,2)-glucan synthase NdvB | VF |
| GUK18_RS23185 () | 72956..74315 | - | 1360 | Protein_51 | heavy metal sensor histidine kinase | - |
| GUK18_RS23190 () | 74315..74986 | - | 672 | WP_024244225.1 | putative transcriptional regulatory protein YedW | VF |
| GUK18_RS23195 () | 75118..75531 | + | 414 | WP_021541665.1 | hydroxyisourate hydrolase | - |
| GUK18_RS23200 () | 75630..76622 | + | 993 | WP_021541666.1 | protein-methionine-sulfoxide reductase catalytic subunit MsrP | - |
| GUK18_RS23205 () | 76623..77258 | + | 636 | WP_021541667.1 | protein-methionine-sulfoxide reductase heme-binding subunit MsrQ | - |
| GUK18_RS23210 () | 77618..78424 | - | 807 | WP_021541668.1 | site-specific integrase | - |
| GUK18_RS23215 () | 78425..78730 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| GUK18_RS23220 () | 78732..78950 | - | 219 | WP_000813639.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| GUK18_RS23225 () | 79547..79804 | + | 258 | WP_021564233.1 | hypothetical protein | - |
| GUK18_RS23230 () | 79804..80394 | + | 591 | WP_021564232.1 | hypothetical protein | - |
| GUK18_RS23235 () | 80777..81955 | - | 1179 | WP_021572468.1 | hypothetical protein | - |
| GUK18_RS23240 () | 82003..82518 | - | 516 | WP_021572469.1 | type 1 fimbrial protein | - |
| GUK18_RS23245 () | 82585..83271 | - | 687 | WP_021572470.1 | molecular chaperone | - |
| GUK18_RS23250 () | 83262..85769 | - | 2508 | WP_021572471.1 | Outer membrane usher protein SfmD | VF |
| GUK18_RS23255 () | 85798..86130 | - | 333 | WP_021541675.1 | fimbria/pilus periplasmic chaperone | - |
| GUK18_RS23260 () | 86216..86920 | - | 705 | WP_021572472.1 | molecular chaperone | - |
| GUK18_RS23265 () | 86996..87601 | - | 606 | WP_021572473.1 | Fimbrial subunit type 1 | VF |
| GUK18_RS23270 () | 88077..88652 | - | 576 | WP_021541677.1 | Tyrosine recombinase XerD | VF |
| GUK18_RS23275 () | 88935..89549 | - | 615 | WP_021564226.1 | 3'-5' exonuclease | - |
| GUK18_RS23280 () | 89687..91219 | - | 1533 | Protein_70 | IS3 family transposase ISKpn38 | Transposase |
| GUK18_RS23285 () | 91261..92019 | + | 759 | Protein_71 | IS66 family transposase ISCro1 | Transposase |
| GUK18_RS23290 () | 92497..93015 | - | 519 | WP_024234541.1 | hypothetical protein | VF |
| GUK18_RS23295 () | 92997..93632 | - | 636 | WP_021564222.1 | hypothetical protein | VF |
| GUK18_RS23300 () | 94575..94776 | - | 202 | Protein_74 | hypothetical protein | - |
| GUK18_RS23305 () | 94773..95351 | - | 579 | WP_021564220.1 | hypothetical protein | - |
| GUK18_RS23310 () | 95454..96227 | - | 774 | WP_021564219.1 | hypothetical protein | VF |
| GUK18_RS23315 () | 96244..97008 | - | 765 | WP_104934207.1 | hypothetical protein | VF |
| GUK18_RS23320 () | 97039..97839 | - | 801 | WP_104934208.1 | hypothetical protein | VF |
| GUK18_RS23325 () | 97954..98733 | - | 780 | WP_024009625.1 | hypothetical protein | - |
| GUK18_RS23330 () | 98966..99748 | - | 783 | WP_158666801.1 | hypothetical protein | - |
| GUK18_RS23335 () | 99984..100109 | - | 126 | Protein_81 | hypothetical protein | VF |
| GUK18_RS23340 () | 100167..100952 | - | 786 | WP_104934218.1 | hypothetical protein | - |
| GUK18_RS23345 () | 101189..101680 | - | 492 | WP_021572479.1 | hypothetical protein | VF |
| GUK18_RS23350 () | 101715..102506 | - | 792 | WP_021572480.1 | Chaperone protein FaeE | VF |
| GUK18_RS23355 () | 102499..104904 | - | 2406 | WP_196105564.1 | F1 capsule-anchoring protein | VF |
| GUK18_RS23360 () | 104952..105488 | - | 537 | WP_050576192.1 | hypothetical protein | VF |
| GUK18_RS23365 () | 106772..106927 | - | 156 | WP_032145292.1 | hypothetical protein | - |
| GUK18_RS23370 () | 107628..108485 | - | 858 | WP_021572483.1 | incFII family plasmid replication initiator RepA | - |
| GUK18_RS23375 () | 108478..108552 | - | 75 | WP_032144212.1 | RepA leader peptide Tap | - |
| GUK18_RS23380 () | 108798..109046 | - | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| GUK18_RS23385 () | 109330..109536 | - | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 109523..109584 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 109523..109584 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 109523..109584 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 109523..109584 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| GUK18_RS23390 () | 109841..109915 | - | 75 | Protein_92 | endonuclease | - |
| GUK18_RS23395 () | 110161..110373 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| GUK18_RS23400 () | 110509..111069 | - | 561 | WP_001587438.1 | fertility inhibition protein FinO | - |
| GUK18_RS23405 () | 111124..111870 | - | 747 | WP_000205759.1 | conjugal transfer pilus acetylase TraX | - |
| GUK18_RS23410 () | 111890..117159 | - | 5270 | Protein_96 | Multifunctional conjugation protein TraI | Relaxase |
| GUK18_RS23415 () | 117241..117468 | + | 228 | WP_000450532.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| GUK18_RS23420 () | 117468..117866 | + | 399 | WP_021572485.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| GUK18_RS23425 () | 117875..120028 | - | 2154 | WP_104934212.1 | type IV conjugative transfer system coupling protein TraD | - |
| GUK18_RS23430 () | 120281..121012 | - | 732 | WP_024244211.1 | complement resistance protein TraT | - |
| GUK18_RS23435 () | 121044..121541 | - | 498 | WP_021572404.1 | surface exclusion inner membrane protein | - |
| GUK18_RS23440 () | 121563..124385 | - | 2823 | WP_021572405.1 | conjugal transfer mating pair stabilization protein TraG | - |
| GUK18_RS23445 () | 124382..125755 | - | 1374 | WP_021572406.1 | conjugal transfer protein TraH | - |
| GUK18_RS23450 () | 125742..126164 | - | 423 | WP_104934213.1 | F-type conjugal transfer protein TrbF | - |
| GUK18_RS23455 () | 126085..126459 | - | 375 | WP_123055397.1 | P-type conjugative transfer protein TrbJ | - |
| GUK18_RS23460 () | 126389..126934 | - | 546 | WP_021572409.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| GUK18_RS23465 () | 126921..127205 | - | 285 | WP_000624108.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| GUK18_RS23470 () | 127286..127591 | + | 306 | Protein_108 | toxin ArtA | - |
| GUK18_RS23475 () | 127601..127948 | - | 348 | WP_021572411.1 | conjugal transfer protein TrbA | - |
| GUK18_RS23480 () | 127964..128707 | - | 744 | WP_040100298.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| GUK18_RS23485 () | 128700..128957 | - | 258 | WP_158666802.1 | conjugal transfer protein TrbE | - |
| GUK18_RS23490 () | 128984..130792 | - | 1809 | WP_104934215.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| GUK18_RS23495 () | 130789..131427 | - | 639 | WP_021572414.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| GUK18_RS23500 () | 131436..132428 | - | 993 | WP_001712363.1 | conjugal transfer pilus assembly protein TraU | - |
| GUK18_RS23505 () | 132425..133057 | - | 633 | WP_021572416.1 | type-F conjugative transfer system protein TraW | - |
| GUK18_RS23510 () | 133054..133407 | - | 354 | WP_104934216.1 | type-F conjugative transfer system protein TrbI | - |
| GUK18_RS23515 () | 133404..136031 | - | 2628 | WP_104934217.1 | type IV secretion system protein TraC | - |
| GUK18_RS23520 () | 136191..136412 | - | 222 | WP_001774296.1 | conjugal transfer protein TraR | - |
| GUK18_RS23525 () | 136547..137062 | - | 516 | WP_000809906.1 | type IV conjugative transfer system lipoprotein TraV | - |
| GUK18_RS23530 () | 137059..137310 | - | 252 | WP_097510255.1 | conjugal transfer protein TrbG | - |
| GUK18_RS23535 () | 137322..137552 | - | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| GUK18_RS23540 () | 137506..138096 | - | 591 | WP_000002787.1 | conjugal transfer protein TraP | - |
| GUK18_RS23545 () | 138086..139513 | - | 1428 | WP_021572422.1 | conjugal transfer protein TraB | - |
| GUK18_RS23550 () | 139513..140217 | - | 705 | WP_157903668.1 | type-F conjugative transfer system secretin TraK | - |
| GUK18_RS23555 () | 140228..140794 | - | 567 | WP_001717262.1 | type IV conjugative transfer system protein TraE | - |
| GUK18_RS23560 () | 140816..141127 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| GUK18_RS23565 () | 141142..141507 | - | 366 | WP_000340270.1 | type IV conjugative transfer system pilin TraA | - |
| GUK18_RS23570 () | 141541..141768 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| GUK18_RS23575 () | 141862..142548 | - | 687 | WP_000332492.1 | PAS domain-containing protein | - |
| GUK18_RS23580 () | 142738..143121 | - | 384 | WP_021572424.1 | relaxosome protein TraM | - |
| GUK18_RS23585 () | 143443..144045 | + | 603 | WP_077695337.1 | hypothetical protein | VF |
| GUK18_RS23590 () | 144341..145162 | - | 822 | WP_021572426.1 | DUF945 domain-containing protein | - |
| GUK18_RS23595 () | 145281..145568 | - | 288 | WP_021572427.1 | hypothetical protein | - |
| GUK18_RS23600 () | 145724..146026 | - | 303 | WP_001272235.1 | hypothetical protein | - |
| GUK18_RS23605 () | 146326..146686 | + | 361 | Protein_135 | hypothetical protein | - |
| GUK18_RS23610 () | 146924..147082 | - | 159 | WP_001302184.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 147147..147345 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 147147..147345 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 147147..147345 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 147147..147345 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| GUK18_RS23615 () | 147357..148076 | - | 720 | WP_021572429.1 | plasmid SOS inhibition protein A | - |
| GUK18_RS23620 () | 148073..148507 | - | 435 | WP_021572430.1 | conjugation system SOS inhibitor PsiB | - |
| GUK18_RS23625 () | 148562..150520 | - | 1959 | WP_021572431.1 | ParB/RepB/Spo0J family partition protein | - |
| GUK18_RS23630 () | 150584..150817 | - | 234 | WP_000005988.1 | DUF905 family protein | - |
| GUK18_RS23635 () | 150880..151419 | - | 540 | WP_000290811.1 | single-stranded DNA-binding protein | - |
| GUK18_RS23640 () | 151445..151651 | - | 207 | WP_000547969.1 | hypothetical protein | - |
| GUK18_RS23645 () | 152204..152395 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| GUK18_RS23650 () | 152399..153641 | + | 1243 | Protein_144 | translesion error-prone DNA polymerase V subunit UmuC | - |
| GUK18_RS23655 () | 153782..154744 | - | 963 | WP_021572436.1 | ParB/RepB/Spo0J family partition protein | - |
| GUK18_RS23660 () | 154741..155946 | - | 1206 | WP_000817642.1 | Plasmid partition protein A | VF |
| GUK18_RS23665 () | 156316..156489 | + | 174 | WP_021576053.1 | hypothetical protein | - |
| GUK18_RS23670 () | 156663..156914 | + | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| GUK18_RS23675 () | 156911..157198 | + | 288 | WP_001270421.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| GUK18_RS23680 () | 157200..157605 | + | 406 | Protein_150 | DDE-type integrase/transposase/recombinase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|