MGE detailed information
MGE type: Conjugative plasmid MGE length: 133446 bp
Accession: NZ_CP043336 Location: 1..133446 Organism: Escherichia coli strain WCHEC115106 Replicon: plasmid p1_115106
Accession: NZ_CP043336 Location: 1..133446 Organism: Escherichia coli strain WCHEC115106 Replicon: plasmid p1_115106
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FZC46_RS23620 (1) | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| FZC46_RS23625 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| FZC46_RS23630 (2124) | 2124..2319 | - | 196 | Protein_2 | serine/threonine protein kinase | - |
| FZC46_RS23635 (2406) | 2406..2816 | - | 411 | Protein_3 | IS3 family transposase ISEhe3 | Transposase |
| FZC46_RS23640 (2879) | 2879..3583 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FZC46_RS23645 (3637) | 3637..4104 | + | 468 | Protein_5 | conjugal transfer protein | - |
| FZC46_RS23650 (4349) | 4349..4465 | + | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| FZC46_RS23655 (4481) | 4481..6400 | + | 1920 | WP_025989258.1 | Tetracycline resistance protein TetM from transposon TnFO1 | VF |
| FZC46_RS23660 (6519) | 6519..6686 | + | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| FZC46_RS23665 (6694) | 6694..6924 | - | 231 | WP_136655701.1 | hypothetical protein | - |
| FZC46_RS23670 (6947) | 6947..7579 | + | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| FZC46_RS23675 (7826) | 7826..8158 | - | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| FZC46_RS23680 (8281) | 8281..9119 | - | 839 | Protein_12 | Streptomycin 3''-adenylyltransferase | ARG |
| FZC46_RS23685 (9212) | 9212..10471 | - | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| FZC46_RS23690 (10686) | 10686..11524 | - | 839 | Protein_14 | Streptomycin 3''-adenylyltransferase | ARG |
| FZC46_RS23695 (11530) | 11530..11820 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| FZC46_RS23700 (11932) | 11932..12429 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| FZC46_RS23705 (12574) | 12574..13587 | + | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| FZC46_RS23710 (13790) | 13790..14140 | + | 351 | WP_071830595.1 | DUF3330 domain-containing protein | - |
| FZC46_RS23715 (14266) | 14266..14826 | + | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| FZC46_RS23720 (14829) | 14829..17780 | + | 2952 | WP_015344976.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| FZC46_RS23725 (17714) | 17714..18190 | + | 477 | WP_223171565.1 | hypothetical protein | - |
| FZC46_RS23730 (18275) | 18275..18979 | - | 705 | WP_001067784.1 | IS6 family transposase IS1006 | Transposase |
| FZC46_RS23735 (19043) | 19043..19873 | + | 831 | Protein_23 | IS91 family transposase ISVsa3 | Transposase |
| FZC46_RS23740 (19904) | 19904..20788 | + | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| FZC46_RS23745 (21005) | 21005..22219 | + | 1215 | WP_193112594.1 | Bicyclomycin resistance protein | ARG |
| FZC46_RS23750 (22247) | 22247..22552 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| FZC46_RS23755 (22664) | 22664..24157 | + | 1494 | WP_015344975.1 | IS91 family transposase ISVsa3 | Transposase |
| FZC46_RS23760 (24393) | 24393..24635 | - | 243 | Protein_28 | phosphoglucosamine mutase | - |
| FZC46_RS23765 (24722) | 24722..25537 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| FZC46_RS23770 (25627) | 25627..26717 | + | 1091 | WP_085940648.1 | IS4-like element ISAba1 family transposase | - |
| FZC46_RS23775 (26914) | 26914..27201 | - | 288 | WP_230071785.1 | hypothetical protein | - |
| FZC46_RS23780 (27449) | 27449..28153 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FZC46_RS23785 (28219) | 28219..29733 | + | 1515 | Protein_33 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FZC46_RS23790 (29791) | 29791..30033 | + | 243 | WP_000844627.1 | transposase | - |
| FZC46_RS23795 (30065) | 30065..30715 | - | 651 | WP_001493764.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| FZC46_RS23800 (30821) | 30821..32020 | + | 1200 | WP_001493765.1 | Tetracycline resistance protein, class C | ARG |
| FZC46_RS23805 (32052) | 32052..32936 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| FZC46_RS23810 (33074) | 33074..33508 | - | 435 | WP_223963367.1 | isochorismatase family cysteine hydrolase | - |
| FZC46_RS23815 (33471) | 33471..35132 | + | 1662 | Protein_39 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FZC46_RS23820 (35234) | 35234..35491 | + | 258 | WP_231363335.1 | hypothetical protein | - |
| FZC46_RS23825 (35600) | 35600..36304 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FZC46_RS23830 (36357) | 36357..37154 | - | 798 | Protein_42 | IS91 family transposase ISMno23 | Transposase |
| FZC46_RS23835 (37303) | 37303..38141 | + | 839 | Protein_43 | Streptomycin 3''-adenylyltransferase | ARG |
| FZC46_RS23840 (38226) | 38226..39047 | + | 822 | WP_000939727.1 | hypothetical protein | ARG |
| FZC46_RS23845 (39200) | 39200..39904 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FZC46_RS23850 (40196) | 40196..40753 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| FZC46_RS23855 (40936) | 40936..41796 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| FZC46_RS23860 (42054) | 42054..42845 | - | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| FZC46_RS23865 (43314) | 43314..43559 | - | 246 | WP_001354008.1 | GrpB family protein | - |
| FZC46_RS23870 (43597) | 43597..44460 | - | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| FZC46_RS23875 (44606) | 44606..44857 | - | 252 | Protein_51 | hypothetical protein | - |
| FZC46_RS23880 (44909) | 44909..45613 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FZC46_RS23885 (45764) | 45764..46579 | + | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| FZC46_RS23890 (46769) | 46769..47473 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FZC46_RS23895 (48010) | 48010..48552 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| FZC46_RS23900 (48565) | 48565..49425 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| FZC46_RS23905 (49568) | 49568..50062 | + | 495 | Protein_57 | IS4 family transposase IS10R | Transposase |
| FZC46_RS23910 (50116) | 50116..50820 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FZC46_RS23915 (50888) | 50888..52186 | + | 1299 | Protein_59 | Tn3 family transposase TnpA_Tn3 | Transposase |
| FZC46_RS23920 (52220) | 52220..52720 | + | 501 | Protein_60 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FZC46_RS23925 (52754) | 52754..52942 | + | 189 | Protein_61 | IS3 family transposase | - |
| FZC46_RS23930 (53017) | 53017..53304 | - | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| FZC46_RS23935 (53301) | 53301..53552 | - | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| FZC46_RS23940 (54518) | 54518..55375 | - | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| FZC46_RS23945 (55368) | 55368..55442 | - | 75 | WP_061357229.1 | RepA leader peptide Tap | - |
| FZC46_RS23950 (55674) | 55674..55931 | - | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| FZC46_RS23955 (56199) | 56199..56348 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (56392) | 56392..56453 | + | 62 | NuclAT_1 | - | - |
| - (56392) | 56392..56453 | + | 62 | NuclAT_1 | - | - |
| - (56392) | 56392..56453 | + | 62 | NuclAT_1 | - | - |
| - (56392) | 56392..56453 | + | 62 | NuclAT_1 | - | - |
| FZC46_RS23960 (56795) | 56795..57007 | - | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| FZC46_RS23965 (57142) | 57142..57702 | - | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| FZC46_RS23970 (57757) | 57757..58209 | - | 453 | WP_241420250.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| FZC46_RS23975 (58229) | 58229..63499 | - | 5271 | WP_054377139.1 | Multifunctional conjugation protein TraI | Relaxase |
| FZC46_RS23980 (63499) | 63499..65679 | - | 2181 | WP_063078088.1 | type IV conjugative transfer system coupling protein TraD | - |
| FZC46_RS23985 (65932) | 65932..66663 | - | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| FZC46_RS23990 (66695) | 66695..67198 | - | 504 | WP_000605510.1 | hypothetical protein | - |
| FZC46_RS23995 (67213) | 67213..70035 | - | 2823 | WP_001007048.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| FZC46_RS24000 (70032) | 70032..71405 | - | 1374 | WP_170926237.1 | conjugal transfer pilus assembly protein TraH | - |
| FZC46_RS24005 (71405) | 71405..71767 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| FZC46_RS24010 (71697) | 71697..72242 | - | 546 | WP_000052613.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| FZC46_RS24015 (72229) | 72229..72465 | - | 237 | WP_054377141.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| FZC46_RS24020 (72626) | 72626..73369 | - | 744 | WP_039002205.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| FZC46_RS24025 (73362) | 73362..73622 | - | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| FZC46_RS24030 (73649) | 73649..75457 | - | 1809 | WP_000821844.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| FZC46_RS24035 (75454) | 75454..76092 | - | 639 | WP_000777691.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| FZC46_RS24040 (76101) | 76101..77093 | - | 993 | WP_023148235.1 | conjugal transfer pilus assembly protein TraU | - |
| FZC46_RS24045 (77090) | 77090..77722 | - | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| FZC46_RS24050 (77719) | 77719..78105 | - | 387 | WP_039002198.1 | type-F conjugative transfer system protein TrbI | - |
| FZC46_RS24055 (78102) | 78102..80729 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| FZC46_RS24060 (80889) | 80889..81110 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| FZC46_RS24065 (81245) | 81245..81760 | - | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| FZC46_RS24070 (81757) | 81757..82077 | - | 321 | WP_063078087.1 | conjugal transfer protein TrbD | - |
| FZC46_RS24075 (82064) | 82064..82651 | - | 588 | WP_000002772.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| FZC46_RS24080 (82641) | 82641..84068 | - | 1428 | WP_000146690.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| FZC46_RS24085 (84068) | 84068..84796 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| FZC46_RS24090 (84783) | 84783..85349 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| FZC46_RS24095 (85371) | 85371..85682 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| FZC46_RS24100 (85687) | 85687..86049 | - | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| FZC46_RS24105 (86082) | 86082..86483 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| FZC46_RS24110 (86576) | 86576..87265 | - | 690 | WP_039002187.1 | conjugal transfer transcriptional regulator TraJ | - |
| FZC46_RS24115 (87452) | 87452..87835 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| FZC46_RS24120 (88156) | 88156..88758 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| FZC46_RS24125 (89055) | 89055..89876 | - | 822 | WP_072795862.1 | DUF932 domain-containing protein | - |
| FZC46_RS24130 (89998) | 89998..90285 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| FZC46_RS24135 (90310) | 90310..90516 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| FZC46_RS24140 (90586) | 90586..90759 | + | 174 | Protein_104 | hypothetical protein | - |
| FZC46_RS24145 (90757) | 90757..90987 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| FZC46_RS24150 (91207) | 91207..91332 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| FZC46_RS24155 (91274) | 91274..91423 | - | 150 | Protein_107 | plasmid maintenance protein Mok | - |
| - (91409) | 91409..91633 | - | 225 | NuclAT_0 | - | - |
| - (91409) | 91409..91633 | - | 225 | NuclAT_0 | - | - |
| - (91409) | 91409..91633 | - | 225 | NuclAT_0 | - | - |
| - (91409) | 91409..91633 | - | 225 | NuclAT_0 | - | - |
| FZC46_RS24160 (91445) | 91445..91633 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| FZC46_RS24165 (91602) | 91602..92364 | - | 763 | Protein_109 | plasmid SOS inhibition protein A | - |
| FZC46_RS24170 (92361) | 92361..92795 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| FZC46_RS24175 (92850) | 92850..94808 | - | 1959 | WP_241420247.1 | ParB/RepB/Spo0J family partition protein | - |
| FZC46_RS24180 (94873) | 94873..95106 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| FZC46_RS24185 (95163) | 95163..95702 | - | 540 | WP_032332913.1 | single-stranded DNA-binding protein | - |
| FZC46_RS24190 (95728) | 95728..95934 | - | 207 | WP_000275853.1 | hypothetical protein | - |
| FZC46_RS24195 (96175) | 96175..96402 | - | 228 | WP_071961421.1 | hypothetical protein | - |
| FZC46_RS24200 (96554) | 96554..97117 | - | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| FZC46_RS24205 (97165) | 97165..98526 | - | 1362 | WP_038999961.1 | DUF3560 domain-containing protein | - |
| FZC46_RS24210 (98578) | 98578..98808 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| FZC46_RS24215 (99845) | 99845..100036 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| FZC46_RS24220 (100033) | 100033..100455 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| FZC46_RS24225 (100502) | 100502..100927 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| FZC46_RS24230 (101344) | 101344..102120 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| FZC46_RS24235 (102171) | 102171..102689 | - | 519 | WP_241420251.1 | DUF1380 family protein | - |
| FZC46_RS24240 (102619) | 102619..102840 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| FZC46_RS24245 (102841) | 102841..103524 | - | 684 | WP_000086185.1 | DNA methylase | - |
| FZC46_RS24250 (103601) | 103601..103912 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| FZC46_RS24255 (103909) | 103909..104811 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| FZC46_RS24260 (105229) | 105229..105477 | + | 249 | WP_000618110.1 | DinI-like family protein | - |
| FZC46_RS24265 (105474) | 105474..105911 | + | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| FZC46_RS24270 (105911) | 105911..107182 | + | 1272 | WP_000457518.1 | Y-family DNA polymerase | - |
| FZC46_RS24275 (107187) | 107187..107579 | - | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| FZC46_RS24280 (107584) | 107584..108555 | - | 972 | WP_001103690.1 | plasmid segregation protein ParM | - |
| FZC46_RS24285 (108777) | 108777..109421 | + | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| FZC46_RS24290 (109415) | 109415..109690 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| FZC46_RS24295 (109842) | 109842..110618 | - | 777 | Protein_135 | site-specific integrase | - |
| FZC46_RS24300 (110615) | 110615..111121 | - | 507 | WP_001505085.1 | hypothetical protein | - |
| FZC46_RS24305 (111112) | 111112..111816 | + | 705 | WP_001505086.1 | IS6 family transposase IS26 | Transposase |
| FZC46_RS24310 (111965) | 111965..113290 | - | 1326 | WP_021512928.1 | reactive chlorine resistance oxidoreductase RclA | - |
| FZC46_RS24315 (113400) | 113400..114097 | + | 698 | WP_114161604.1 | IS1 family transposase IS1R | Transposase |
| FZC46_RS24320 (114198) | 114198..114479 | - | 282 | WP_000639434.1 | hypothetical protein | - |
| FZC46_RS24325 (114581) | 114581..115474 | - | 894 | Protein_141 | IS3 family transposase ISEhe3 | Transposase |
| FZC46_RS24330 (115542) | 115542..116360 | + | 819 | Protein_142 | IS30 family transposase IS30D | Transposase |
| FZC46_RS24340 (117695) | 117695..117844 | + | 150 | Protein_144 | IS30 family transposase | - |
| FZC46_RS24345 (118269) | 118269..118553 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| FZC46_RS24350 (118573) | 118573..119706 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| FZC46_RS24355 (119969) | 119969..120871 | - | 903 | WP_241420248.1 | hypothetical protein | - |
| FZC46_RS24360 (120995) | 120995..121183 | + | 189 | WP_048230572.1 | hypothetical protein | - |
| FZC46_RS24365 (121193) | 121193..122392 | + | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| FZC46_RS24370 (122548) | 122548..123294 | - | 747 | WP_241420249.1 | hypothetical protein | - |
| FZC46_RS24375 (123345) | 123345..124175 | - | 831 | WP_223201786.1 | hypothetical protein | - |
| FZC46_RS24380 (124227) | 124227..124775 | - | 549 | WP_039002808.1 | hypothetical protein | - |
| FZC46_RS24385 (125081) | 125081..125311 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| FZC46_RS24390 (125308) | 125308..125724 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FZC46_RS24395 (125886) | 125886..128024 | - | 2139 | WP_039002805.1 | AAA family ATPase | - |
| FZC46_RS24400 (128489) | 128489..129484 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| FZC46_RS24405 (129488) | 129488..130420 | + | 933 | WP_000991832.1 | S-4TM family putative pore-forming effector | - |
| FZC46_RS24415 (131402) | 131402..131560 | + | 159 | WP_228955855.1 | abortive infection family protein | - |
| FZC46_RS24420 (131719) | 131719..132691 | - | 973 | Protein_160 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|