MGE detailed information
MGE type: Conjugative plasmid MGE length: 110724 bp
Accession: NZ_CP043297 Location: 1..110724 Organism: Escherichia coli strain WCHEC040047 Replicon: plasmid p1_040047
Accession: NZ_CP043297 Location: 1..110724 Organism: Escherichia coli strain WCHEC040047 Replicon: plasmid p1_040047
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FYK54_RS24815 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| FYK54_RS24820 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| FYK54_RS24825 (2124) | 2124..2312 | - | 189 | WP_001312821.1 | hypothetical protein | - |
| FYK54_RS24830 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| FYK54_RS24835 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| FYK54_RS24840 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| FYK54_RS24845 (7449) | 7449..7628 | - | 180 | Protein_6 | integrase core domain-containing protein | - |
| FYK54_RS24850 (7767) | 7767..8980 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| FYK54_RS24855 (9128) | 9128..9396 | - | 269 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| FYK54_RS24860 (9453) | 9453..10150 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| FYK54_RS24865 (10167) | 10167..10364 | - | 198 | Protein_10 | colicin V | - |
| FYK54_RS24870 (10342) | 10342..10578 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| FYK54_RS24875 (11120) | 11120..11323 | - | 204 | Protein_12 | hypothetical protein | - |
| FYK54_RS24880 (11496) | 11496..11663 | + | 168 | Protein_13 | colicin-B | - |
| FYK54_RS24885 (11681) | 11681..12208 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| FYK54_RS24890 (12452) | 12452..13267 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| FYK54_RS24895 (13317) | 13317..13670 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| FYK54_RS24900 (13848) | 13848..14639 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| FYK54_RS24905 (14636) | 14636..15325 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| FYK54_RS24910 (15369) | 15369..15719 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| FYK54_RS24915 (16264) | 16264..17352 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| FYK54_RS24920 (17354) | 17354..19579 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| FYK54_RS24925 (19629) | 19629..20528 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| FYK54_RS24930 (20518) | 20518..20808 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| FYK54_RS24935 (21104) | 21104..21334 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| FYK54_RS24940 (21331) | 21331..21747 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FYK54_RS24945 (21909) | 21909..23297 | - | 1389 | Protein_26 | AAA family ATPase | - |
| FYK54_RS24950 (23361) | 23361..24065 | + | 705 | WP_001067834.1 | IS6-like element IS26 family transposase | - |
| FYK54_RS24955 (24437) | 24437..24886 | - | 450 | WP_039021304.1 | hypothetical protein | - |
| FYK54_RS24960 (24897) | 24897..25436 | - | 540 | WP_039021305.1 | hypothetical protein | - |
| FYK54_RS24965 (26109) | 26109..26813 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| FYK54_RS24970 (26878) | 26878..27492 | - | 615 | Protein_31 | Bcr/CflA family efflux MFS transporter | - |
| FYK54_RS24975 (27813) | 27813..28265 | - | 453 | WP_000237816.1 | NAD(+)--rifampin ADP-ribosyltransferase Arr-2 | - |
| FYK54_RS24980 (28438) | 28438..29550 | + | 1113 | WP_024166810.1 | class 1 integron integrase IntI1 | - |
| FYK54_RS24985 (29496) | 29496..30200 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FYK54_RS24990 (31088) | 31088..31336 | + | 249 | Protein_35 | IS1380 family transposase ISEcp1 | Transposase |
| FYK54_RS24995 (31339) | 31339..31425 | + | 87 | Protein_36 | hypothetical protein | - |
| FYK54_RS25000 (31456) | 31456..31797 | + | 342 | WP_004202492.1 | Multiple antibiotic resistance protein MarA | VF |
| FYK54_RS25005 (31815) | 31815..32063 | - | 249 | WP_065809026.1 | IS6 family transposase IS15DII | Transposase |
| FYK54_RS25010 (32355) | 32355..32564 | - | 210 | Protein_39 | IS6 family transposase IS15DII | Transposase |
| FYK54_RS25015 (32630) | 32630..33973 | + | 1344 | Protein_40 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FYK54_RS25020 (34024) | 34024..34728 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| FYK54_RS25025 (34835) | 34835..35695 | + | 861 | WP_000557452.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| FYK54_RS25030 (35708) | 35708..36250 | + | 543 | WP_002063889.1 | AAA family ATPase | - |
| FYK54_RS25035 (36342) | 36342..37390 | + | 1049 | Protein_44 | IS3 family transposase ISKpn11 | Transposase |
| FYK54_RS25040 (37444) | 37444..37728 | - | 285 | Protein_45 | IS6 family transposase IS26 | Transposase |
| FYK54_RS25045 (37794) | 37794..38498 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| FYK54_RS25050 (38564) | 38564..39109 | + | 546 | Protein_47 | Tn3 family transposase TnpA_Tn3 | Transposase |
| FYK54_RS25055 (39145) | 39145..39560 | - | 416 | Protein_48 | IS1-like element IS1B family transposase | - |
| FYK54_RS25060 (39809) | 39809..40210 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| FYK54_RS25065 (40143) | 40143..40400 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| FYK54_RS25070 (40493) | 40493..41146 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| FYK54_RS25075 (42085) | 42085..42942 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| FYK54_RS25080 (42935) | 42935..43417 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| FYK54_RS25085 (43410) | 43410..43457 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| FYK54_RS25090 (43448) | 43448..43699 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| FYK54_RS25095 (43716) | 43716..43973 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| FYK54_RS25100 (44257) | 44257..44406 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (44450) | 44450..44511 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (44450) | 44450..44511 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (44450) | 44450..44511 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (44450) | 44450..44511 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| FYK54_RS25105 (44767) | 44767..44841 | - | 75 | Protein_58 | endonuclease | - |
| FYK54_RS25110 (45087) | 45087..45299 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| FYK54_RS25115 (45435) | 45435..45995 | - | 561 | WP_112917249.1 | fertility inhibition protein FinO | - |
| FYK54_RS25120 (46098) | 46098..46958 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
| FYK54_RS25125 (47017) | 47017..47763 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| FYK54_RS25130 (47783) | 47783..53053 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| FYK54_RS25135 (53135) | 53135..53362 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| FYK54_RS25140 (53362) | 53362..53760 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FYK54_RS25145 (53769) | 53769..54125 | - | 357 | Protein_66 | conjugal transfer protein TraD | - |
| FYK54_RS25150 (54162) | 54162..54839 | + | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| FYK54_RS25155 (54839) | 54839..55186 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| FYK54_RS25160 (55206) | 55206..56777 | + | 1572 | WP_029392005.1 | IS66 family transposase ISCro1 | Transposase |
| FYK54_RS25165 (56809) | 56809..58629 | - | 1821 | Protein_70 | type IV conjugative transfer system coupling protein TraD | - |
| FYK54_RS25170 (58882) | 58882..59613 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| FYK54_RS25175 (59645) | 59645..60142 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| FYK54_RS25180 (60158) | 60158..62980 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| FYK54_RS25185 (62977) | 62977..64350 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| FYK54_RS25190 (64350) | 64350..64730 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| FYK54_RS25195 (64717) | 64717..65058 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| FYK54_RS25200 (64988) | 64988..65533 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| FYK54_RS25205 (65520) | 65520..65804 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| FYK54_RS25210 (65885) | 65885..66199 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| FYK54_RS25215 (66201) | 66201..66548 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| FYK54_RS25220 (66564) | 66564..67307 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| FYK54_RS25225 (67300) | 67300..67557 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| FYK54_RS25230 (67584) | 67584..69392 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| FYK54_RS25235 (69389) | 69389..70027 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| FYK54_RS25240 (70036) | 70036..71028 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| FYK54_RS25245 (71025) | 71025..71657 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| FYK54_RS25250 (71654) | 71654..72040 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| FYK54_RS25255 (72037) | 72037..74664 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| FYK54_RS25260 (74824) | 74824..75045 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| FYK54_RS25265 (75180) | 75180..75695 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| FYK54_RS25270 (75692) | 75692..75943 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| FYK54_RS25275 (75955) | 75955..76152 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| FYK54_RS25280 (76139) | 76139..76729 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| FYK54_RS25285 (76719) | 76719..78146 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| FYK54_RS25290 (78146) | 78146..78874 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| FYK54_RS25295 (78861) | 78861..79427 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| FYK54_RS25300 (79449) | 79449..79760 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| FYK54_RS25305 (79775) | 79775..80140 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| FYK54_RS25310 (80173) | 80173..80574 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| FYK54_RS25315 (80667) | 80667..81356 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| FYK54_RS25320 (81543) | 81543..81926 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| FYK54_RS25325 (82247) | 82247..82849 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| FYK54_RS25330 (83146) | 83146..83967 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| FYK54_RS25335 (84085) | 84085..84372 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| FYK54_RS25340 (84397) | 84397..84603 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| FYK54_RS25345 (84673) | 84673..84845 | + | 173 | Protein_106 | hypothetical protein | - |
| FYK54_RS25350 (84843) | 84843..85073 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| FYK54_RS25355 (85293) | 85293..85418 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| FYK54_RS25360 (85360) | 85360..85509 | - | 150 | Protein_109 | plasmid maintenance protein Mok | - |
| - (85495) | 85495..85719 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (85495) | 85495..85719 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (85495) | 85495..85719 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (85495) | 85495..85719 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| FYK54_RS25365 (85531) | 85531..85719 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| FYK54_RS25370 (85688) | 85688..86450 | - | 763 | Protein_111 | plasmid SOS inhibition protein A | - |
| FYK54_RS25375 (86447) | 86447..86881 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| FYK54_RS25380 (86936) | 86936..87133 | - | 198 | Protein_113 | hypothetical protein | - |
| FYK54_RS25385 (87161) | 87161..87394 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| FYK54_RS25390 (87462) | 87462..88001 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| FYK54_RS25395 (88027) | 88027..88233 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| FYK54_RS25400 (88303) | 88303..88383 | + | 81 | Protein_117 | hypothetical protein | - |
| FYK54_RS25405 (88566) | 88566..88735 | - | 170 | Protein_118 | hypothetical protein | - |
| FYK54_RS25410 (89372) | 89372..90343 | - | 972 | WP_112917248.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| FYK54_RS25415 (90343) | 90343..91509 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| FYK54_RS25425 (92991) | 92991..95192 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| FYK54_RS25430 (95218) | 95218..96551 | - | 1334 | Protein_123 | L-lysine N6-monooxygenase | VF |
| FYK54_RS25435 (96548) | 96548..98290 | - | 1743 | WP_112917266.1 | Aerobactin synthase | VF |
| FYK54_RS25440 (98290) | 98290..99237 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| FYK54_RS25445 (99238) | 99238..100962 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| FYK54_RS25450 (101098) | 101098..102291 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| FYK54_RS25455 (102671) | 102671..103051 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| FYK54_RS25460 (103392) | 103392..103805 | - | 414 | Protein_129 | phosphopyruvate hydratase | - |
| FYK54_RS25465 (103803) | 103803..104060 | + | 258 | Protein_130 | Tn3 family transposase | - |
| FYK54_RS25470 (104294) | 104294..105151 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| FYK54_RS25475 (105148) | 105148..106005 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| FYK54_RS25480 (106002) | 106002..106829 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| FYK54_RS25485 (106829) | 106829..107743 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| FYK54_RS25490 (108099) | 108099..108796 | + | 698 | WP_094096600.1 | IS1 family transposase IS1S | Transposase |
| FYK54_RS25495 (108976) | 108976..109489 | - | 514 | Protein_136 | DUF4113 domain-containing protein | - |
| FYK54_RS25500 (109550) | 109550..109654 | - | 105 | Protein_137 | AAA family ATPase | - |
| FYK54_RS25505 (109656) | 109656..109979 | - | 324 | Protein_138 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|