MGE detailed information
MGE type: Conjugative plasmid MGE length: 111058 bp
Accession: NZ_CP043286 Location: 1..111058 Organism: Escherichia coli strain WCHEC025985 Replicon: plasmid pCTXM55_025985
Accession: NZ_CP043286 Location: 1..111058 Organism: Escherichia coli strain WCHEC025985 Replicon: plasmid pCTXM55_025985
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FYK42_RS24010 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| FYK42_RS24015 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| FYK42_RS24020 (2124) | 2124..2312 | - | 189 | WP_241408125.1 | serine/threonine protein kinase | - |
| FYK42_RS24025 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| FYK42_RS24030 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| FYK42_RS24035 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| FYK42_RS24040 (6256) | 6256..6645 | + | 390 | WP_001332050.1 | outer membrane protease | - |
| FYK42_RS24045 (7449) | 7449..7628 | - | 180 | Protein_7 | integrase core domain-containing protein | - |
| FYK42_RS24050 (7767) | 7767..8980 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| FYK42_RS24055 (9128) | 9128..9396 | - | 269 | Protein_9 | IS3 family transposase ISLad1 | Transposase |
| FYK42_RS24060 (9453) | 9453..10150 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| FYK42_RS24065 (10167) | 10167..10364 | - | 198 | Protein_11 | colicin V | - |
| FYK42_RS24070 (10342) | 10342..10578 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| FYK42_RS24075 (11120) | 11120..11323 | - | 204 | Protein_13 | hypothetical protein | - |
| FYK42_RS24080 (11496) | 11496..11663 | + | 168 | Protein_14 | colicin-B | - |
| FYK42_RS24085 (11681) | 11681..12208 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| FYK42_RS24090 (12452) | 12452..13267 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| FYK42_RS24095 (13317) | 13317..13670 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| FYK42_RS24100 (13848) | 13848..14639 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| FYK42_RS24105 (14636) | 14636..15325 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| FYK42_RS24110 (15369) | 15369..15719 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| FYK42_RS24115 (16264) | 16264..17352 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| FYK42_RS24120 (17354) | 17354..19579 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| FYK42_RS24125 (19629) | 19629..20528 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| FYK42_RS24130 (20518) | 20518..20808 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| FYK42_RS24135 (21104) | 21104..21334 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| FYK42_RS24140 (21331) | 21331..21747 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FYK42_RS24145 (21909) | 21909..24047 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| FYK42_RS24150 (24401) | 24401..24658 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| FYK42_RS24155 (24658) | 24658..25248 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| FYK42_RS24160 (25511) | 25511..27067 | + | 1557 | WP_000818556.1 | AAA family ATPase | - |
| FYK42_RS24165 (27259) | 27259..27624 | + | 366 | Protein_31 | proQ/FINO family protein | - |
| FYK42_RS24170 (27716) | 27716..28944 | + | 1229 | WP_088895425.1 | IS3 family transposase IS2 | Transposase |
| FYK42_RS24175 (28955) | 28955..29212 | + | 258 | Protein_33 | ProQ/FINO family protein | - |
| FYK42_RS24180 (29505) | 29505..30584 | - | 1080 | WP_001089727.1 | permease | - |
| FYK42_RS24185 (30689) | 30689..31012 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| FYK42_RS24190 (31173) | 31173..31493 | + | 321 | Protein_36 | NAD(P)H-dependent oxidoreductase | - |
| FYK42_RS24195 (31546) | 31546..32250 | - | 705 | WP_001067855.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| FYK42_RS24200 (32275) | 32275..32451 | + | 177 | WP_077874304.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| FYK42_RS24205 (32633) | 32633..33895 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| FYK42_RS24210 (34151) | 34151..35026 | + | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| FYK42_RS24215 (35073) | 35073..35366 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| FYK42_RS24220 (35431) | 35431..37650 | + | 2220 | Protein_42 | Tn3 family transposase TnpA_Tn3 | Transposase |
| FYK42_RS24225 (37727) | 37727..38431 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| FYK42_RS24230 (38736) | 38736..38840 | + | 105 | Protein_44 | recombinase family protein | - |
| FYK42_RS24235 (38892) | 38892..39596 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| FYK42_RS24240 (39646) | 39646..40212 | - | 567 | Protein_46 | penicillin-binding transpeptidase domain-containing protein | - |
| FYK42_RS24245 (40477) | 40477..41736 | - | 1260 | WP_012300772.1 | Bicyclomycin resistance protein | ARG |
| FYK42_RS24250 (42057) | 42057..42509 | - | 453 | WP_000237816.1 | hypothetical protein | ARG |
| FYK42_RS24255 (42620) | 42620..43093 | - | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| FYK42_RS24260 (43249) | 43249..44028 | + | 780 | Protein_50 | IS91 family transposase ISAzo26 | Transposase |
| FYK42_RS24265 (44088) | 44088..44792 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| FYK42_RS24270 (44846) | 44846..45160 | + | 315 | Protein_52 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| FYK42_RS24275 (45163) | 45163..48129 | + | 2967 | WP_001138070.1 | Tn3 family transposase | - |
| FYK42_RS24280 (48208) | 48208..49212 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| FYK42_RS24285 (49484) | 49484..49570 | - | 87 | Protein_55 | Arm DNA-binding domain-containing protein | - |
| FYK42_RS24290 (49900) | 49900..50715 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| FYK42_RS24295 (50776) | 50776..51579 | + | 804 | WP_001082320.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| FYK42_RS24300 (51579) | 51579..52415 | + | 837 | WP_000480972.1 | hypothetical protein | ARG |
| FYK42_RS24305 (52646) | 52646..53506 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| FYK42_RS24310 (53689) | 53689..54150 | - | 462 | Protein_60 | Tn3 family transposase TnpR_Tn3 | Transposase |
| FYK42_RS24315 (54214) | 54214..54918 | + | 705 | WP_001067855.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| FYK42_RS24320 (54971) | 54971..55768 | - | 798 | Protein_62 | IS91 family transposase ISAzo26 | Transposase |
| FYK42_RS24325 (55917) | 55917..56755 | + | 839 | Protein_63 | Streptomycin 3''-adenylyltransferase | ARG |
| FYK42_RS24330 (56840) | 56840..57661 | + | 822 | WP_000939727.1 | hypothetical protein | ARG |
| FYK42_RS24335 (57814) | 57814..58518 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| FYK42_RS24340 (58584) | 58584..59129 | + | 546 | Protein_66 | Tn3 family transposase TnpA_Tn3 | Transposase |
| FYK42_RS24345 (59165) | 59165..59580 | - | 416 | Protein_67 | IS1-like element IS1B family transposase | - |
| FYK42_RS24350 (59829) | 59829..60230 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| FYK42_RS24355 (60163) | 60163..60420 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| FYK42_RS24360 (60513) | 60513..61166 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| FYK42_RS24365 (62105) | 62105..62962 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| FYK42_RS24370 (62955) | 62955..63437 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| FYK42_RS24375 (63430) | 63430..63477 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| FYK42_RS24380 (63468) | 63468..63719 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| FYK42_RS24385 (63736) | 63736..63993 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| FYK42_RS24390 (64277) | 64277..64426 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (64470) | 64470..64531 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (64470) | 64470..64531 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (64470) | 64470..64531 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (64470) | 64470..64531 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| FYK42_RS24395 (64787) | 64787..64861 | - | 75 | Protein_77 | endonuclease | - |
| FYK42_RS24400 (65107) | 65107..65319 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| FYK42_RS24405 (65455) | 65455..66015 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| FYK42_RS24410 (66118) | 66118..66978 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
| FYK42_RS24415 (67037) | 67037..67783 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| FYK42_RS24420 (67803) | 67803..73073 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| FYK42_RS24425 (73155) | 73155..73382 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| FYK42_RS24430 (73382) | 73382..73780 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FYK42_RS24435 (73789) | 73789..75579 | - | 1791 | Protein_85 | type IV conjugative transfer system coupling protein TraD | - |
| FYK42_RS24440 (75575) | 75575..76816 | - | 1242 | Protein_86 | conjugal transfer mating-pair stabilization protein TraG | - |
| FYK42_RS24445 (76813) | 76813..78186 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| FYK42_RS24450 (78186) | 78186..78566 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| FYK42_RS24455 (78553) | 78553..78789 | - | 237 | WP_241408124.1 | conjugal transfer protein TrbJ | - |
| FYK42_RS24460 (78776) | 78776..79072 | - | 297 | Protein_90 | conjugal transfer protein TraB | - |
| FYK42_RS24465 (79194) | 79194..79760 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| FYK42_RS24470 (79782) | 79782..80093 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| FYK42_RS24475 (80108) | 80108..80473 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| FYK42_RS24480 (80506) | 80506..80907 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| FYK42_RS24485 (81000) | 81000..81689 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| FYK42_RS24490 (81876) | 81876..82259 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| FYK42_RS24495 (82580) | 82580..83182 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| FYK42_RS24500 (83479) | 83479..84300 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| FYK42_RS24505 (84418) | 84418..84705 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| FYK42_RS24510 (84730) | 84730..84936 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| FYK42_RS24515 (85006) | 85006..85178 | + | 173 | Protein_101 | hypothetical protein | - |
| FYK42_RS24520 (85176) | 85176..85406 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| FYK42_RS24525 (85626) | 85626..85751 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| FYK42_RS24530 (85693) | 85693..85842 | - | 150 | Protein_104 | plasmid maintenance protein Mok | - |
| - (85828) | 85828..86052 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (85828) | 85828..86052 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (85828) | 85828..86052 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (85828) | 85828..86052 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| FYK42_RS24535 (85864) | 85864..86052 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| FYK42_RS24540 (86021) | 86021..86783 | - | 763 | Protein_106 | plasmid SOS inhibition protein A | - |
| FYK42_RS24545 (86780) | 86780..87214 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| FYK42_RS24550 (87269) | 87269..87466 | - | 198 | Protein_108 | hypothetical protein | - |
| FYK42_RS24555 (87494) | 87494..87727 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| FYK42_RS24560 (87795) | 87795..88334 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| FYK42_RS24565 (88360) | 88360..88566 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| FYK42_RS24570 (88636) | 88636..88716 | + | 81 | Protein_112 | hypothetical protein | - |
| FYK42_RS24575 (88899) | 88899..89068 | - | 170 | Protein_113 | hypothetical protein | - |
| FYK42_RS24580 (89705) | 89705..90676 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| FYK42_RS24585 (90676) | 90676..91842 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| FYK42_RS24595 (93324) | 93324..95525 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| FYK42_RS24600 (95551) | 95551..96884 | - | 1334 | Protein_118 | L-lysine N6-monooxygenase | VF |
| FYK42_RS24605 (96881) | 96881..98623 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| FYK42_RS24610 (98623) | 98623..99571 | - | 949 | Protein_120 | N(6)-hydroxylysine O-acetyltransferase | VF |
| FYK42_RS24615 (99572) | 99572..101296 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| FYK42_RS24620 (101432) | 101432..102625 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| FYK42_RS24625 (103005) | 103005..103385 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| FYK42_RS24630 (103726) | 103726..104139 | - | 414 | Protein_124 | phosphopyruvate hydratase | - |
| FYK42_RS24635 (104137) | 104137..104394 | + | 258 | Protein_125 | Tn3 family transposase | - |
| FYK42_RS24640 (104628) | 104628..105485 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| FYK42_RS24645 (105482) | 105482..106339 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| FYK42_RS24650 (106336) | 106336..107163 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| FYK42_RS24655 (107163) | 107163..108077 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| FYK42_RS24660 (108433) | 108433..109130 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| FYK42_RS24665 (109310) | 109310..109823 | - | 514 | Protein_131 | DUF4113 domain-containing protein | - |
| FYK42_RS24670 (109884) | 109884..109988 | - | 105 | Protein_132 | AAA family ATPase | - |
| FYK42_RS24675 (109990) | 109990..110313 | - | 324 | Protein_133 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|