MGE detailed information
MGE type: Conjugative plasmid MGE length: 157660 bp
Accession: NZ_CP041303 Location: 1..157660 Organism: Escherichia coli strain MSHS 133 Replicon: plasmid pCys-11
Accession: NZ_CP041303 Location: 1..157660 Organism: Escherichia coli strain MSHS 133 Replicon: plasmid pCys-11
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FK544_RS00010 () | 43..408 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| FK544_RS00015 () | 441..836 | - | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| FK544_RS00020 () | 935..1623 | - | 689 | Protein_3 | conjugal transfer transcriptional regulator TraJ | - |
| FK544_RS00025 () | 1810..2193 | - | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| FK544_RS00030 () | 2514..3116 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| FK544_RS00035 () | 3413..4234 | - | 822 | WP_001234426.1 | DUF945 domain-containing protein | - |
| FK544_RS00040 () | 4352..4639 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| FK544_RS00055 () | 5560..5718 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 5762..5986 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 5762..5986 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 5762..5986 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 5762..5986 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| FK544_RS25460 () | 5798..5986 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| FK544_RS00060 () | 5998..6717 | - | 720 | WP_001276238.1 | plasmid SOS inhibition protein A | - |
| FK544_RS00065 () | 6714..7148 | - | 435 | WP_000845937.1 | conjugation system SOS inhibitor PsiB | - |
| FK544_RS00070 () | 7203..7400 | - | 198 | Protein_12 | hypothetical protein | - |
| FK544_RS00075 () | 7428..7661 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| FK544_RS00080 () | 7729..8268 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| FK544_RS25610 () | 8294..8500 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| FK544_RS00100 () | 8910..9116 | - | 207 | WP_001774176.1 | hypothetical protein | - |
| FK544_RS00105 () | 9142..9705 | - | 564 | Protein_17 | class I SAM-dependent methyltransferase | - |
| FK544_RS00110 () | 9753..11114 | - | 1362 | WP_000199439.1 | DUF3560 domain-containing protein | - |
| FK544_RS00115 () | 11166..11396 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| FK544_RS00125 () | 11908..12156 | + | 249 | WP_071781657.1 | hypothetical protein | - |
| FK544_RS00130 () | 12428..12619 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| FK544_RS00135 () | 12616..13038 | - | 423 | WP_000271685.1 | DUF1380 family protein | - |
| FK544_RS00140 () | 13085..13387 | - | 303 | WP_072148062.1 | antirestriction protein | - |
| FK544_RS00150 () | 13927..14695 | - | 769 | Protein_24 | hypothetical protein | - |
| FK544_RS00155 () | 14763..15293 | - | 531 | Protein_25 | DUF1380 family protein | - |
| FK544_RS00160 () | 15187..15408 | - | 222 | WP_001104905.1 | hypothetical protein | - |
| FK544_RS00165 () | 15409..16092 | - | 684 | WP_000085939.1 | DNA methylase | - |
| FK544_RS00170 () | 16169..16474 | - | 306 | WP_010892536.1 | hypothetical protein | - |
| FK544_RS25615 () | 16478..17379 | - | 902 | Protein_29 | DUF1281 domain-containing protein | - |
| FK544_RS00185 () | 18117..19088 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| FK544_RS00190 () | 19088..20254 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| FK544_RS00195 () | 20842..21597 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| FK544_RS00200 () | 22319..23125 | - | 807 | WP_000016970.1 | site-specific integrase | - |
| FK544_RS00205 () | 23126..23431 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| FK544_RS00210 () | 23433..23651 | - | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| FK544_RS00220 () | 24211..24441 | + | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| FK544_RS00225 () | 24438..24854 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FK544_RS00230 () | 24929..26494 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| FK544_RS00235 () | 26479..27501 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| FK544_RS00240 () | 27755..28441 | - | 687 | Protein_40 | IS1 family transposase IS1S | Transposase |
| FK544_RS00245 () | 28967..31168 | - | 2202 | WP_000973521.1 | Ferric aerobactin receptor | VF |
| FK544_RS00250 () | 31250..32527 | - | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| FK544_RS00255 () | 32524..34266 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| FK544_RS00260 () | 34266..35213 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| FK544_RS00265 () | 35214..36938 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| FK544_RS00270 () | 37074..38267 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| FK544_RS00275 () | 38647..39027 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| FK544_RS00285 () | 39368..39781 | - | 414 | Protein_48 | phosphopyruvate hydratase | - |
| FK544_RS00290 () | 39779..40036 | + | 258 | Protein_49 | Tn3 family transposase | - |
| FK544_RS00295 () | 40270..41127 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| FK544_RS00300 () | 41124..41981 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| FK544_RS00305 () | 41978..42805 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| FK544_RS00310 () | 42805..43719 | - | 915 | WP_000949005.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| FK544_RS00320 () | 44075..44761 | + | 687 | Protein_54 | IS1 family transposase IS1S | Transposase |
| FK544_RS00325 () | 45057..45215 | + | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| FK544_RS00340 () | 46488..47441 | + | 954 | WP_000280980.1 | Protease 7 | VF |
| FK544_RS00350 () | 47874..48983 | + | 1110 | WP_000771476.1 | SDR family oxidoreductase | - |
| FK544_RS00355 () | 49052..49954 | + | 903 | WP_001312822.1 | hypothetical protein | VF |
| FK544_RS00360 () | 50329..50517 | + | 189 | WP_032146390.1 | hypothetical protein | - |
| FK544_RS00365 () | 50638..51378 | + | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| FK544_RS00370 () | 51657..52634 | - | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| FK544_RS00380 () | 53377..53700 | + | 324 | Protein_62 | IS21 family transposase IS21 | Transposase |
| FK544_RS25620 () | 53702..53806 | + | 105 | Protein_63 | AAA family ATPase | - |
| FK544_RS00390 () | 53867..54380 | + | 514 | Protein_64 | DUF4113 domain-containing protein | - |
| FK544_RS00395 () | 54538..55224 | - | 687 | Protein_65 | IS1 family transposase IS1S | Transposase |
| FK544_RS00400 () | 55275..55564 | - | 290 | Protein_66 | IS3 family transposase IS911 | Transposase |
| FK544_RS00405 () | 56545..57732 | + | 1188 | WP_000928805.1 | efflux RND transporter periplasmic adaptor subunit | - |
| FK544_RS00410 () | 57729..59669 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| FK544_RS00415 () | 59673..61043 | + | 1371 | WP_141841187.1 | efflux transporter outer membrane subunit | - |
| FK544_RS00420 () | 61455..62152 | - | 698 | Protein_70 | IS1 family transposase IS1X4 | Transposase |
| FK544_RS00425 () | 62294..62488 | + | 195 | Protein_71 | IS200/IS605-like element IS200C family transposase | - |
| FK544_RS00430 () | 62617..63558 | - | 942 | WP_000974760.1 | hypothetical protein | - |
| FK544_RS00440 () | 63793..65182 | - | 1390 | Protein_73 | ISNCY family transposase ISKpn21 | Transposase |
| FK544_RS00445 () | 65494..65643 | - | 150 | Protein_74 | IS3 family transposase IS2 | Transposase |
| FK544_RS00450 () | 65821..67014 | - | 1194 | WP_000450492.1 | GTP-binding protein | - |
| FK544_RS00460 () | 68044..68337 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| FK544_RS00465 () | 68395..68594 | - | 200 | Protein_77 | lysis system i-spanin subunit Rz | - |
| FK544_RS00475 () | 69067..70275 | - | 1209 | WP_001352368.1 | IS4 family transposase IS10R | Transposase |
| FK544_RS00480 () | 70486..71584 | + | 1099 | Protein_79 | IS481 family transposase ISKpn28 | Transposase |
| FK544_RS00490 () | 72820..73935 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| FK544_RS00495 () | 74075..77734 | + | 3660 | WP_001318221.1 | Multidrug efflux ATP-binding/permease protein | VF |
| FK544_RS00500 () | 77838..79066 | + | 1229 | Protein_82 | Enterochelin esterase | VF |
| FK544_RS00505 () | 79151..80107 | + | 957 | WP_000271277.1 | Ferri-bacillibactin esterase BesA | VF |
| FK544_RS00510 () | 80152..82329 | - | 2178 | WP_001259003.1 | Ferric enterobactin receptor | VF |
| FK544_RS00515 () | 82633..82893 | - | 261 | WP_000076221.1 | hypothetical protein | - |
| FK544_RS00520 () | 83316..83539 | + | 224 | Protein_86 | autotransporter adhesin family protein | - |
| FK544_RS00525 () | 83625..84031 | - | 407 | Protein_87 | IS3 family transposase ISEc16 | Transposase |
| FK544_RS00530 () | 84354..85838 | - | 1485 | WP_021531208.1 | alpha/beta hydrolase | - |
| FK544_RS00535 () | 86023..86973 | - | 951 | Protein_89 | Protease 7 | VF |
| FK544_RS00540 () | 87404..88632 | + | 1229 | WP_088895425.1 | IS3 family transposase IS2 | Transposase |
| FK544_RS00550 () | 89053..90240 | + | 1188 | WP_000937547.1 | IS91 family transposase ISEc37 | Transposase |
| FK544_RS00555 () | 90601..91209 | - | 609 | WP_000715518.1 | hypothetical protein | - |
| FK544_RS00560 () | 91279..91551 | - | 273 | Protein_93 | hypothetical protein | - |
| FK544_RS00565 () | 91707..92633 | + | 927 | WP_001280608.1 | hypothetical protein | - |
| FK544_RS00570 () | 92677..92931 | + | 255 | WP_000678529.1 | hypothetical protein | - |
| FK544_RS00575 () | 93428..93772 | + | 345 | WP_000793772.1 | hypothetical protein | - |
| FK544_RS25625 () | 93803..93943 | + | 141 | WP_154071810.1 | hypothetical protein | - |
| FK544_RS00580 () | 93956..94957 | - | 1002 | WP_000138754.1 | DUF4238 domain-containing protein | - |
| FK544_RS00590 () | 95329..95559 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| FK544_RS00595 () | 95556..95972 | + | 417 | WP_001044766.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FK544_RS00600 () | 96134..98272 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| FK544_RS00605 () | 98625..98885 | + | 261 | WP_000371881.1 | hypothetical protein | - |
| FK544_RS00610 () | 98882..99472 | + | 591 | WP_001376212.1 | hypothetical protein | - |
| FK544_RS00615 () | 99490..99837 | - | 348 | WP_000142441.1 | hypothetical protein | - |
| FK544_RS00620 () | 100127..100609 | - | 483 | WP_001311056.1 | hypothetical protein | - |
| FK544_RS00625 () | 100726..101574 | - | 849 | WP_001058004.1 | 3'-5' exonuclease | - |
| FK544_RS00630 () | 101620..101901 | - | 282 | WP_000969989.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| FK544_RS00635 () | 101898..102167 | - | 270 | WP_000079941.1 | hypothetical protein | - |
| FK544_RS00640 () | 102778..104052 | + | 1275 | WP_000489607.1 | HlyD family secretion protein | - |
| FK544_RS00645 () | 104027..106141 | + | 2115 | WP_001183605.1 | peptidase domain-containing ABC transporter | - |
| FK544_RS00650 () | 106311..106622 | - | 312 | WP_001259758.1 | colicin V | - |
| FK544_RS00655 () | 106600..106836 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| FK544_RS00660 () | 107493..108179 | + | 687 | Protein_113 | IS1 family transposase IS1S | Transposase |
| FK544_RS00665 () | 108190..108348 | - | 159 | WP_001105071.1 | hypothetical protein | - |
| FK544_RS00670 () | 108521..108688 | + | 168 | Protein_115 | colicin-B | - |
| FK544_RS00675 () | 108706..109233 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| FK544_RS00685 () | 109477..110292 | + | 816 | WP_001318230.1 | lipid II-degrading bacteriocin colicin M | - |
| FK544_RS00690 () | 110342..110695 | - | 354 | WP_000864817.1 | colicin M immunity protein | - |
| FK544_RS00695 () | 110868..111017 | - | 150 | Protein_119 | phage integrase family protein | - |
| FK544_RS00700 () | 111056..111884 | + | 829 | Protein_120 | HAD-IIB family hydrolase | - |
| FK544_RS00705 () | 111884..112900 | + | 1017 | WP_000583429.1 | Gfo/Idh/MocA family oxidoreductase | - |
| FK544_RS00710 () | 112902..113171 | + | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| FK544_RS00715 () | 113168..114700 | + | 1533 | WP_001017345.1 | FAD-dependent oxidoreductase | - |
| FK544_RS00720 () | 114732..115183 | - | 452 | Protein_124 | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase | VF |
| FK544_RS00725 () | 115511..115771 | + | 261 | WP_000371881.1 | hypothetical protein | - |
| FK544_RS00730 () | 115768..116358 | + | 591 | WP_021531027.1 | hypothetical protein | - |
| FK544_RS00735 () | 116378..116716 | - | 339 | WP_000142460.1 | hypothetical protein | - |
| FK544_RS00740 () | 116845..117180 | + | 336 | WP_021531026.1 | immunity protein | - |
| FK544_RS00745 () | 117202..117990 | - | 789 | Protein_129 | hypothetical protein | - |
| FK544_RS00755 () | 118186..118590 | - | 405 | WP_000154256.1 | DUF2251 domain-containing protein | - |
| FK544_RS00760 () | 118760..119047 | - | 288 | WP_000222774.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| FK544_RS00765 () | 119044..119295 | - | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| FK544_RS25535 () | 119419..119559 | - | 141 | WP_161953058.1 | hypothetical protein | - |
| FK544_RS00775 () | 120259..121116 | - | 858 | WP_000774296.1 | incFII family plasmid replication initiator RepA | - |
| FK544_RS00780 () | 121109..121591 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| FK544_RS00785 () | 121584..121658 | - | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| FK544_RS00795 () | 121890..122147 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| FK544_RS00800 () | 122431..122637 | - | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 122624..122685 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 122624..122685 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 122624..122685 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 122624..122685 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| FK544_RS25630 () | 122941..123015 | - | 75 | Protein_139 | endonuclease | - |
| FK544_RS00810 () | 123261..123473 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| FK544_RS00815 () | 123609..124169 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| FK544_RS00820 () | 124272..125132 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
| FK544_RS00825 () | 125191..125937 | - | 747 | WP_000205741.1 | conjugal transfer pilus acetylase TraX | - |
| FK544_RS00830 () | 125957..131227 | - | 5271 | WP_021531024.1 | Multifunctional conjugation protein TraI | Relaxase |
| FK544_RS00835 () | 131309..131536 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | - |
| FK544_RS00840 () | 131536..131934 | + | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| FK544_RS00845 () | 131943..134096 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| FK544_RS00855 () | 134349..134888 | - | 540 | WP_122632586.1 | complement resistance protein TraT | - |
| FK544_RS00860 () | 134896..135126 | - | 231 | WP_141841188.1 | hypothetical protein | - |
| FK544_RS00865 () | 135113..135610 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| FK544_RS00870 () | 135626..138448 | - | 2823 | WP_021531023.1 | conjugal transfer mating pair stabilization protein TraG | - |
| FK544_RS00875 () | 138445..139818 | - | 1374 | WP_001517790.1 | conjugal transfer protein TraH | - |
| FK544_RS00880 () | 139818..140231 | - | 414 | WP_071781659.1 | F-type conjugal transfer protein TrbF | - |
| FK544_RS00885 () | 140185..140526 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| FK544_RS00890 () | 140456..141001 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| FK544_RS00895 () | 140988..141272 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| FK544_RS00900 () | 141353..141667 | + | 315 | WP_000415566.1 | protein ArtA | - |
| FK544_RS00905 () | 141669..142016 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| FK544_RS00910 () | 142032..142775 | - | 744 | WP_001030377.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| FK544_RS00915 () | 142768..143025 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| FK544_RS00920 () | 143052..144860 | - | 1809 | WP_000821838.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| FK544_RS00925 () | 144857..145370 | - | 514 | Protein_162 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| FK544_RS00930 () | 145442..145846 | + | 405 | WP_000839181.1 | IS66 family transposase ISEc22 | Transposase |
| FK544_RS00935 () | 145843..146190 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| FK544_RS00940 () | 146239..147777 | + | 1539 | WP_000099202.1 | IS66 family transposase ISEc22 | Transposase |
| FK544_RS00945 () | 147814..147957 | - | 144 | Protein_166 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| FK544_RS00950 () | 147966..148958 | - | 993 | WP_000830180.1 | conjugal transfer pilus assembly protein TraU | - |
| FK544_RS00955 () | 148955..149587 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| FK544_RS00960 () | 149584..149970 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| FK544_RS00965 () | 149967..152594 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| FK544_RS00970 () | 152754..152975 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| FK544_RS00975 () | 153110..153625 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| FK544_RS00980 () | 153622..153873 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| FK544_RS00985 () | 153885..154115 | - | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| FK544_RS00990 () | 154069..154659 | - | 591 | WP_000002787.1 | conjugal transfer protein TraP | - |
| FK544_RS00995 () | 154649..156076 | - | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| FK544_RS01000 () | 156076..156780 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| FK544_RS01005 () | 156791..157357 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|