MGE detailed information
MGE type: Conjugative plasmid MGE length: 134611 bp
Accession: NZ_CP034401 Location: 1..134611 Organism: Escherichia coli strain CRE10 Replicon: plasmid pCRE10.1
Accession: NZ_CP034401 Location: 1..134611 Organism: Escherichia coli strain CRE10 Replicon: plasmid pCRE10.1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EJC75_RS00010 () | 231..863 | - | 633 | WP_001203727.1 | type-F conjugative transfer system protein TraW | - |
| EJC75_RS00015 () | 860..1246 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| EJC75_RS00020 () | 1243..3870 | - | 2628 | WP_001064258.1 | type IV secretion system protein TraC | - |
| EJC75_RS00025 () | 4030..4251 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| EJC75_RS00030 () | 4386..4901 | - | 516 | WP_000809886.1 | type IV conjugative transfer system lipoprotein TraV | - |
| EJC75_RS00035 () | 4901..5260 | - | 360 | WP_001617876.1 | conjugal transfer protein TrbD | - |
| EJC75_RS00040 () | 5199..5786 | - | 588 | WP_071587349.1 | conjugal transfer protein TraP | - |
| EJC75_RS00045 () | 5755..7206 | - | 1452 | WP_000146687.1 | conjugal transfer protein TraB | - |
| EJC75_RS00050 () | 7206..7910 | - | 705 | WP_148725207.1 | type-F conjugative transfer system secretin TraK | - |
| EJC75_RS00055 () | 7921..8487 | - | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| EJC75_RS00060 () | 8509..8820 | - | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| EJC75_RS00065 () | 8825..9187 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| EJC75_RS00070 () | 9221..9448 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| EJC75_RS00075 () | 9536..10213 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| EJC75_RS00080 () | 10347..10730 | - | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| EJC75_RS00085 () | 11061..11663 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| EJC75_RS00090 () | 11960..12781 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| EJC75_RS00095 () | 12900..13187 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| EJC75_RS00100 () | 13438..14418 | + | 981 | WP_032154316.1 | IS110 family transposase IS1663 | Transposase |
| EJC75_RS26355 () | 14604..14795 | - | 192 | Protein_20 | single-stranded DNA-binding protein | - |
| EJC75_RS00120 () | 15486..15644 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 15688..15726 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - () | 15688..15726 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - () | 15688..15726 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - () | 15688..15726 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - () | 17166..17268 | - | 103 | NuclAT_0 | - | - |
| - () | 17166..17268 | - | 103 | NuclAT_0 | - | - |
| - () | 17166..17268 | - | 103 | NuclAT_0 | - | - |
| - () | 17166..17268 | - | 103 | NuclAT_0 | - | - |
| EJC75_RS00130 () | 17280..17999 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| EJC75_RS00135 () | 17996..18430 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| EJC75_RS00140 () | 18485..20443 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| EJC75_RS00145 () | 20509..20742 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| EJC75_RS00150 () | 20805..21344 | - | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| EJC75_RS00155 () | 21596..22576 | + | 981 | WP_032154316.1 | IS110 family transposase IS1663 | Transposase |
| EJC75_RS00180 () | 23364..23576 | - | 213 | WP_001348622.1 | hypothetical protein | - |
| EJC75_RS00185 () | 23602..24165 | - | 564 | WP_129483993.1 | class I SAM-dependent methyltransferase | - |
| EJC75_RS00190 () | 24213..25574 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| EJC75_RS00195 () | 25626..25856 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| EJC75_RS00205 () | 26891..27082 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| EJC75_RS00210 () | 27079..27501 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| EJC75_RS00215 () | 27548..27850 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| EJC75_RS00225 () | 28390..29166 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| EJC75_RS00230 () | 29217..29651 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| EJC75_RS00235 () | 29665..29886 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| EJC75_RS00240 () | 29887..30570 | - | 684 | WP_000086185.1 | DNA methylase | - |
| EJC75_RS00245 () | 30647..30951 | - | 305 | Protein_40 | hypothetical protein | - |
| EJC75_RS00250 () | 30955..31857 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| EJC75_RS00265 () | 32724..33695 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| EJC75_RS00270 () | 33695..34861 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| EJC75_RS00275 () | 35449..36204 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| EJC75_RS00280 () | 36978..37784 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| EJC75_RS00285 () | 37785..38090 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| EJC75_RS00290 () | 38092..38310 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| EJC75_RS00295 () | 38944..39141 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| EJC75_RS00300 () | 39138..39422 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| EJC75_RS00305 () | 39442..40575 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| EJC75_RS00310 () | 40838..43957 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| EJC75_RS00320 () | 44264..44494 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| EJC75_RS00325 () | 44491..44907 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| EJC75_RS00330 () | 45069..47207 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| EJC75_RS00335 () | 47672..48667 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| EJC75_RS00340 () | 48671..49603 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| EJC75_RS00345 () | 49740..50437 | - | 698 | Protein_57 | IS1 family transposase IS1G | Transposase |
| EJC75_RS00350 () | 50651..53767 | - | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| EJC75_RS00355 () | 53889..55172 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| EJC75_RS00360 () | 55169..56725 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| EJC75_RS00365 () | 56908..57129 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| EJC75_RS00370 () | 57129..57509 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| EJC75_RS00375 () | 57514..57693 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| EJC75_RS00380 () | 57721..58080 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| EJC75_RS00385 () | 58004..58417 | + | 414 | Protein_65 | IS3 family transposase ISLad1 | Transposase |
| EJC75_RS00395 () | 59213..60190 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| EJC75_RS00400 () | 60475..61215 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| EJC75_RS00405 () | 61336..61518 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| EJC75_RS00415 () | 61861..62168 | - | 308 | Protein_69 | type II toxin-antitoxin system ParD family antitoxin | - |
| EJC75_RS00425 () | 62661..63830 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| EJC75_RS00430 () | 63863..63991 | + | 129 | Protein_71 | IS481 family transposase | - |
| EJC75_RS00435 () | 64026..64220 | - | 195 | WP_086258557.1 | hypothetical protein | - |
| EJC75_RS00440 () | 64262..64959 | + | 698 | Protein_73 | IS1 family transposase IS1R | Transposase |
| EJC75_RS00445 () | 64966..65487 | + | 522 | Protein_74 | IS4 family transposase IS10R | Transposase |
| EJC75_RS00450 () | 65497..65868 | - | 372 | WP_035689358.1 | Transposon Tn10 TetD protein | VF |
| EJC75_RS00455 () | 66001..66594 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| EJC75_RS00460 () | 66707..67912 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| EJC75_RS00465 () | 67994..68617 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| EJC75_RS00470 () | 68595..68714 | - | 120 | Protein_79 | ArsR family transcriptional regulator | - |
| EJC75_RS00475 () | 68730..69427 | - | 698 | Protein_80 | IS1 family transposase IS1R | Transposase |
| EJC75_RS00480 () | 69591..70295 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| EJC75_RS00485 () | 70349..70594 | - | 246 | Protein_82 | NAD(+)--rifampin ADP-ribosyltransferase | - |
| EJC75_RS00490 () | 70679..71311 | - | 633 | WP_000186237.1 | Chloramphenicol acetyltransferase | VF |
| EJC75_RS00495 () | 71449..72279 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| EJC75_RS00500 () | 72410..72964 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| EJC75_RS00505 () | 73108..73812 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EJC75_RS00510 () | 73877..74557 | - | 681 | Protein_87 | IS91 family transposase ISAzo26 | Transposase |
| EJC75_RS00515 () | 74715..75188 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| EJC75_RS00520 () | 75319..76107 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| EJC75_RS00525 () | 76313..76660 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| EJC75_RS00530 () | 76654..77241 | + | 588 | Protein_91 | dihydropteroate synthase | - |
| EJC75_RS00535 () | 77307..78011 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| EJC75_RS00545 () | 78140..78904 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| EJC75_RS00560 () | 79397..79981 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| EJC75_RS00565 () | 79981..81219 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| EJC75_RS00570 () | 81216..82121 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| EJC75_RS00580 () | 82243..82947 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| EJC75_RS00585 () | 83106..83387 | - | 282 | Protein_98 | transposase zinc-binding domain-containing protein | - |
| EJC75_RS00590 () | 83534..84394 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| EJC75_RS00595 () | 84577..84915 | - | 339 | Protein_100 | Tn3 family transposase TnpR_Tn3 | Transposase |
| EJC75_RS00600 () | 84979..85683 | + | 705 | WP_001067855.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| EJC75_RS00605 () | 85744..86580 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| EJC75_RS00610 () | 86580..87383 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| EJC75_RS00615 () | 87444..88259 | - | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| EJC75_RS00625 () | 88567..89418 | - | 852 | WP_000240536.1 | replication protein | - |
| EJC75_RS00630 () | 89405..90124 | - | 720 | Protein_106 | AAA family ATPase | - |
| EJC75_RS00640 () | 90174..90878 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| EJC75_RS00645 () | 90915..92042 | - | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| EJC75_RS00650 () | 92093..92320 | - | 228 | WP_000248278.1 | hypothetical protein | - |
| EJC75_RS00655 () | 92344..92535 | + | 192 | WP_000951934.1 | hypothetical protein | - |
| EJC75_RS00660 () | 93017..93559 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| EJC75_RS00665 () | 93572..94432 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| EJC75_RS00675 () | 94575..95537 | + | 963 | Protein_113 | IS4 family transposase IS10R | Transposase |
| EJC75_RS00680 () | 95647..96552 | + | 906 | Protein_114 | IS4 family transposase IS10R | Transposase |
| EJC75_RS00685 () | 96601..97305 | - | 705 | WP_001067858.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| EJC75_RS26360 () | 97369..97515 | + | 147 | Protein_116 | Tn3 family transposase TnpR_Tn3 | Transposase |
| EJC75_RS00695 () | 97698..98558 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| EJC75_RS00700 () | 98708..98806 | - | 99 | Protein_118 | IS1 family transposase | - |
| EJC75_RS00705 () | 98835..100145 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| EJC75_RS00710 () | 100430..100831 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| EJC75_RS00715 () | 100764..101021 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| EJC75_RS00720 () | 101114..101767 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| EJC75_RS26115 () | 101865..102005 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| EJC75_RS00730 () | 102706..103563 | - | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| EJC75_RS00735 () | 103556..103630 | - | 75 | WP_014966221.1 | RepA leader peptide Tap | - |
| EJC75_RS26365 () | 103627..103761 | - | 135 | Protein_126 | protein CopA/IncA | - |
| EJC75_RS00745 () | 103992..105533 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| EJC75_RS00750 () | 105548..106278 | + | 731 | Protein_128 | IS21 family transposase ISEc12 | Transposase |
| EJC75_RS00755 () | 106438..106692 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| EJC75_RS00760 () | 106989..107123 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 107168..107228 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 107168..107228 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 107168..107228 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 107168..107228 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| EJC75_RS26120 () | 107195..107481 | - | 287 | Protein_131 | DUF2726 domain-containing protein | - |
| EJC75_RS00775 () | 107994..108206 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| EJC75_RS00780 () | 108337..108897 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| EJC75_RS00785 () | 108952..109698 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| EJC75_RS00790 () | 109718..114987 | - | 5270 | Protein_135 | Multifunctional conjugation protein TraI | Relaxase |
| EJC75_RS00795 () | 114987..117185 | - | 2199 | WP_024623315.1 | type IV conjugative transfer system coupling protein TraD | - |
| EJC75_RS00800 () | 117182..117961 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| EJC75_RS00805 () | 118164..118895 | - | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| EJC75_RS00810 () | 118927..119424 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| EJC75_RS00815 () | 119443..122262 | - | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| EJC75_RS00820 () | 122259..123631 | - | 1373 | Protein_141 | conjugal transfer protein TraH | - |
| EJC75_RS00825 () | 123618..124043 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| EJC75_RS00830 () | 123991..124338 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| EJC75_RS00835 () | 124268..124813 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| EJC75_RS00840 () | 124800..125084 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| EJC75_RS00845 () | 125211..125531 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| EJC75_RS00850 () | 125579..126276 | - | 698 | Protein_147 | IS1 family transposase IS1G | Transposase |
| EJC75_RS00855 () | 126431..127204 | - | 774 | Protein_148 | IS5 family transposase ISKpn26 | Transposase |
| EJC75_RS00860 () | 127287..127691 | + | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| EJC75_RS00865 () | 127688..128035 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| EJC75_RS00870 () | 128084..129619 | + | 1536 | WP_001333339.1 | IS66 family transposase ISEc22 | Transposase |
| EJC75_RS00875 () | 129662..129874 | - | 213 | Protein_152 | IS5/IS1182 family transposase | - |
| EJC75_RS00880 () | 130004..130747 | - | 744 | WP_001030401.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| EJC75_RS00885 () | 130740..130997 | - | 258 | WP_000864347.1 | conjugal transfer protein TrbE | - |
| EJC75_RS00890 () | 131024..132874 | - | 1851 | WP_000821866.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| EJC75_RS00895 () | 132871..133509 | - | 639 | WP_001080259.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| EJC75_RS00900 () | 133518..133823 | - | 306 | WP_000224413.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|