MGE detailed information
MGE type: Conjugative plasmid MGE length: 146286 bp
Accession: NZ_CP033159 Location: 1..146286 Organism: Escherichia coli strain CM IVRI KOL-1 Replicon: plasmid p1ESCUMpO83_CORR
Accession: NZ_CP033159 Location: 1..146286 Organism: Escherichia coli strain CM IVRI KOL-1 Replicon: plasmid p1ESCUMpO83_CORR
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EAF06_RS23630 () | 291..482 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| EAF06_RS23635 () | 479..897 | - | 419 | Protein_1 | DUF1380 family protein | - |
| EAF06_RS23640 () | 944..1246 | - | 303 | WP_001666994.1 | antirestriction protein | - |
| EAF06_RS23650 () | 1783..2553 | - | 771 | WP_001006251.1 | hypothetical protein | - |
| EAF06_RS23655 () | 2598..3032 | - | 435 | WP_001546462.1 | DUF1380 family protein | - |
| EAF06_RS23660 () | 3046..3267 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| EAF06_RS23665 () | 3268..3951 | - | 684 | WP_032181561.1 | DNA methylase | - |
| EAF06_RS23670 () | 4028..4332 | - | 305 | Protein_7 | hypothetical protein | - |
| EAF06_RS23675 () | 4336..5238 | - | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| EAF06_RS23680 () | 5976..6947 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| EAF06_RS23685 () | 6947..8113 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| EAF06_RS23690 () | 8701..9456 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| EAF06_RS23695 () | 10178..10984 | - | 807 | WP_000016970.1 | site-specific integrase | - |
| EAF06_RS23700 () | 10985..11290 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| EAF06_RS23705 () | 11292..11510 | - | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| EAF06_RS23710 () | 12070..12300 | + | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| EAF06_RS23715 () | 12297..12713 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| EAF06_RS23720 () | 12788..14353 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| EAF06_RS23725 () | 14338..15360 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| EAF06_RS23730 () | 15614..16300 | - | 687 | Protein_19 | IS1 family transposase IS1S | Transposase |
| EAF06_RS23735 () | 16450..17147 | - | 698 | Protein_20 | IS1 family transposase IS1X2 | Transposase |
| EAF06_RS24980 () | 17347..17460 | + | 114 | Protein_21 | IS6 family transposase | - |
| EAF06_RS23740 () | 17610..17768 | + | 159 | WP_000449408.1 | DsbA family protein | - |
| EAF06_RS23745 () | 17758..18264 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| EAF06_RS23750 () | 18447..19262 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| EAF06_RS23755 () | 19609..21495 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| EAF06_RS23760 () | 21536..22063 | + | 528 | WP_000178050.1 | iron transporter | - |
| EAF06_RS23765 () | 22167..23546 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| EAF06_RS23770 () | 23549..24832 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| EAF06_RS23775 () | 24822..25952 | + | 1131 | WP_000729219.1 | ABC transporter permease | - |
| EAF06_RS23780 () | 25957..26652 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| EAF06_RS23785 () | 26639..27124 | + | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| EAF06_RS23790 () | 27149..27634 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| EAF06_RS23795 () | 27756..28388 | + | 633 | Protein_33 | histidine-type phosphatase | - |
| EAF06_RS23800 () | 28538..28642 | - | 105 | Protein_34 | IS5/IS1182 family transposase | - |
| EAF06_RS23805 () | 28676..31090 | - | 2415 | Protein_35 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| EAF06_RS23810 () | 31148..31852 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EAF06_RS23815 () | 31974..32888 | + | 915 | WP_023063803.1 | hypothetical protein | ARG |
| EAF06_RS23820 () | 32885..34122 | + | 1238 | Protein_38 | MFS transporter | - |
| EAF06_RS23825 () | 34122..34706 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| EAF06_RS23830 () | 35199..35963 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| EAF06_RS23835 () | 36265..36822 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| EAF06_RS23840 () | 37005..37865 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| EAF06_RS23845 () | 38035..38790 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| EAF06_RS23850 () | 38871..39419 | - | 549 | WP_014342204.1 | cation:proton antiporter | - |
| EAF06_RS23855 () | 39482..39832 | + | 351 | Protein_45 | 60 kDa chaperonin | VF |
| EAF06_RS23860 () | 40026..40730 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EAF06_RS23865 () | 40895..41188 | + | 294 | Protein_47 | IS30 family transposase ISAba125 | Transposase |
| EAF06_RS23870 () | 41289..42101 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| EAF06_RS23875 () | 42105..42470 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| EAF06_RS23880 () | 42475..43113 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| EAF06_RS23885 () | 43124..44155 | - | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| EAF06_RS23890 () | 44468..46009 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| EAF06_RS23895 () | 46414..47253 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| EAF06_RS23900 () | 47247..47594 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| EAF06_RS23905 () | 47758..48549 | - | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| EAF06_RS23910 () | 48555..48845 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| EAF06_RS23915 () | 48957..49454 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| EAF06_RS23920 () | 49599..50465 | + | 867 | Protein_58 | IS91 family transposase ISAzo26 | Transposase |
| EAF06_RS23925 () | 50520..51224 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EAF06_RS23930 () | 51290..52804 | + | 1515 | Protein_60 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| EAF06_RS23935 () | 52846..53088 | + | 243 | WP_032140899.1 | hypothetical protein | - |
| EAF06_RS23940 () | 53120..53770 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| EAF06_RS23945 () | 53876..55075 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| EAF06_RS23950 () | 55107..55991 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| EAF06_RS23955 () | 56129..56536 | - | 408 | WP_001214976.1 | cysteine hydrolase | - |
| EAF06_RS23960 () | 56525..57274 | + | 750 | Protein_66 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| EAF06_RS23965 () | 57298..57903 | - | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| EAF06_RS23970 () | 57998..60895 | + | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| EAF06_RS23975 () | 61032..61433 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| EAF06_RS23980 () | 61366..61623 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| EAF06_RS23985 () | 61716..62369 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| EAF06_RS23990 () | 63308..64165 | - | 858 | WP_029702152.1 | incFII family plasmid replication initiator RepA | - |
| EAF06_RS23995 () | 64158..64232 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| EAF06_RS24000 () | 64468..64725 | - | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| EAF06_RS24005 () | 65009..65215 | - | 207 | WP_032215358.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 65202..65263 | + | 62 | NuclAT_1 | - | - |
| - () | 65202..65263 | + | 62 | NuclAT_1 | - | - |
| - () | 65202..65263 | + | 62 | NuclAT_1 | - | - |
| - () | 65202..65263 | + | 62 | NuclAT_1 | - | - |
| EAF06_RS24985 () | 65402..65668 | - | 267 | WP_087757657.1 | hypothetical protein | - |
| EAF06_RS24015 () | 66043..66612 | - | 570 | WP_029702150.1 | DUF2726 domain-containing protein | - |
| EAF06_RS24020 () | 66764..67390 | - | 627 | WP_029702149.1 | hypothetical protein | - |
| EAF06_RS24025 () | 67802..68011 | - | 210 | WP_039023209.1 | hypothetical protein | - |
| EAF06_RS24030 () | 68142..68702 | - | 561 | WP_001567328.1 | fertility inhibition protein FinO | - |
| EAF06_RS24035 () | 68757..69503 | - | 747 | WP_052273601.1 | conjugal transfer pilus acetylase TraX | - |
| EAF06_RS24040 () | 69531..70277 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| EAF06_RS24045 () | 70292..71833 | - | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| EAF06_RS24050 () | 72109..77379 | - | 5271 | WP_039023145.1 | Multifunctional conjugation protein TraI | Relaxase |
| EAF06_RS24055 () | 77461..77688 | + | 228 | WP_039023146.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| EAF06_RS24060 () | 77688..78086 | + | 399 | WP_039023147.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| EAF06_RS24065 () | 78095..80302 | - | 2208 | WP_039052471.1 | type IV conjugative transfer system coupling protein TraD | - |
| EAF06_RS24070 () | 80555..81286 | - | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| EAF06_RS24075 () | 81318..81815 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| EAF06_RS24080 () | 81834..84653 | - | 2820 | WP_039023149.1 | conjugal transfer mating pair stabilization protein TraG | - |
| EAF06_RS24085 () | 84650..86023 | - | 1374 | WP_039023150.1 | conjugal transfer protein TraH | - |
| EAF06_RS24090 () | 86023..86385 | - | 363 | WP_071550055.1 | P-type conjugative transfer protein TrbJ | - |
| EAF06_RS24095 () | 86315..86860 | - | 546 | WP_016236310.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| EAF06_RS24100 () | 86847..87131 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| EAF06_RS24105 () | 87250..87597 | - | 348 | WP_001287894.1 | conjugal transfer protein TrbA | - |
| EAF06_RS24110 () | 87613..88356 | - | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| EAF06_RS24115 () | 88349..88606 | - | 258 | WP_039023152.1 | conjugal transfer protein TrbE | - |
| EAF06_RS24120 () | 88633..90441 | - | 1809 | WP_039023153.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| EAF06_RS24125 () | 90438..91076 | - | 639 | WP_001553832.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| EAF06_RS24130 () | 91085..92077 | - | 993 | WP_001553833.1 | conjugal transfer pilus assembly protein TraU | - |
| EAF06_RS24135 () | 92074..92706 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| EAF06_RS24140 () | 92703..93089 | - | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| EAF06_RS24145 () | 93086..94147 | - | 1062 | Protein_103 | type IV secretion system protein TraC | - |
| EAF06_RS24150 () | 94196..95565 | + | 1370 | WP_085947770.1 | IS3 family transposase IS150 | Transposase |
| EAF06_RS24155 () | 95591..97158 | - | 1568 | Protein_105 | TraC family protein | - |
| EAF06_RS24160 () | 97318..97539 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| EAF06_RS24165 () | 97674..98189 | - | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
| EAF06_RS24170 () | 98186..98437 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| EAF06_RS24175 () | 98430..98591 | - | 162 | WP_000741714.1 | conjugal transfer protein TrbD | - |
| EAF06_RS24180 () | 98613..98750 | - | 138 | WP_001553834.1 | conjugal transfer protein TrbD | - |
| EAF06_RS24185 () | 98737..99327 | - | 591 | WP_000002787.1 | conjugal transfer protein TraP | - |
| EAF06_RS24190 () | 99317..100744 | - | 1428 | WP_001553836.1 | conjugal transfer protein TraB | - |
| EAF06_RS24195 () | 100744..101448 | - | 705 | WP_148713163.1 | type-F conjugative transfer system secretin TraK | - |
| EAF06_RS24200 () | 101459..102025 | - | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| EAF06_RS24205 () | 102047..102358 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| EAF06_RS24210 () | 102373..102738 | - | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| EAF06_RS24215 () | 102781..102996 | - | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| EAF06_RS24220 () | 103131..103778 | - | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| EAF06_RS24225 () | 103969..104352 | - | 384 | WP_001063020.1 | relaxosome protein TraM | - |
| EAF06_RS24230 () | 104722..105294 | + | 573 | WP_000949660.1 | hypothetical protein | VF |
| EAF06_RS24235 () | 105590..106411 | - | 822 | WP_001234465.1 | DUF945 domain-containing protein | - |
| EAF06_RS24240 () | 106530..106817 | - | 288 | WP_000107242.1 | hypothetical protein | - |
| EAF06_RS24990 () | 106842..107048 | - | 207 | WP_000275854.1 | hypothetical protein | - |
| EAF06_RS24250 () | 107716..107874 | - | 159 | WP_001302184.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 107939..108137 | - | 199 | NuclAT_0 | - | - |
| - () | 107939..108137 | - | 199 | NuclAT_0 | - | - |
| - () | 107939..108137 | - | 199 | NuclAT_0 | - | - |
| - () | 107939..108137 | - | 199 | NuclAT_0 | - | - |
| EAF06_RS24255 () | 108106..108211 | - | 106 | Protein_125 | plasmid SOS inhibition protein A | - |
| EAF06_RS24260 () | 108366..108683 | + | 318 | Protein_126 | IS110 family transposase IS1618 | Transposase |
| EAF06_RS24265 () | 108972..109223 | - | 252 | Protein_127 | iron-containing alcohol dehydrogenase | - |
| EAF06_RS24270 () | 109308..109931 | - | 624 | WP_000912556.1 | potassium channel family protein | - |
| EAF06_RS24275 () | 109947..110640 | - | 694 | Protein_129 | IS1 family transposase IS1A | Transposase |
| EAF06_RS24280 () | 110697..110801 | + | 105 | Protein_130 | thiosulfate reductase cytochrome B subunit | - |
| EAF06_RS24285 () | 111047..112440 | - | 1394 | Protein_131 | carbohydrate porin | - |
| EAF06_RS24290 () | 112635..114068 | - | 1434 | WP_024170639.1 | glycoside hydrolase family 32 protein | - |
| EAF06_RS24295 () | 114065..115341 | - | 1277 | Protein_133 | MFS transporter | - |
| EAF06_RS24300 () | 115404..117530 | - | 2127 | WP_000253905.1 | alpha-galactosidase | - |
| EAF06_RS24305 () | 117626..118636 | - | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
| EAF06_RS24310 () | 118794..119552 | - | 759 | Protein_136 | site-specific integrase | - |
| EAF06_RS24315 () | 119643..120871 | + | 1229 | WP_152924612.1 | IS3 family transposase IS2 | Transposase |
| EAF06_RS24320 () | 120856..121425 | + | 570 | WP_089634947.1 | hypothetical protein | - |
| EAF06_RS24995 () | 122525..122759 | - | 235 | Protein_139 | hypothetical protein | - |
| EAF06_RS24330 () | 122785..123348 | - | 564 | WP_029702196.1 | class I SAM-dependent methyltransferase | - |
| EAF06_RS24335 () | 123395..124756 | - | 1362 | WP_039023242.1 | DUF3560 domain-containing protein | - |
| EAF06_RS24340 () | 124808..125038 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| EAF06_RS24345 () | 125555..125803 | + | 249 | WP_071781657.1 | hypothetical protein | - |
| EAF06_RS24350 () | 126075..126266 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| EAF06_RS24355 () | 126263..126685 | - | 423 | WP_000271685.1 | DUF1380 family protein | - |
| EAF06_RS24360 () | 126732..127034 | - | 303 | WP_001666994.1 | antirestriction protein | - |
| EAF06_RS24375 () | 127571..128341 | - | 771 | WP_001006251.1 | hypothetical protein | - |
| EAF06_RS24380 () | 128386..128820 | - | 435 | WP_001546462.1 | DUF1380 family protein | - |
| EAF06_RS24385 () | 128834..129055 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| EAF06_RS24390 () | 129056..129739 | - | 684 | WP_032181561.1 | DNA methylase | - |
| EAF06_RS24395 () | 129816..130120 | - | 305 | Protein_151 | hypothetical protein | - |
| EAF06_RS24400 () | 130124..131026 | - | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| EAF06_RS24405 () | 131764..132735 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| EAF06_RS24410 () | 132735..133897 | - | 1163 | Protein_154 | plasmid-partitioning protein SopA | - |
| EAF06_RS24415 () | 134482..135126 | - | 645 | WP_001477618.1 | replication initiation protein RepE | - |
| EAF06_RS24420 () | 135952..136758 | - | 807 | WP_000016970.1 | site-specific integrase | - |
| EAF06_RS24425 () | 136759..137063 | - | 305 | Protein_157 | type II toxin-antitoxin system toxin CcdB | - |
| EAF06_RS24430 () | 137065..137283 | - | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| EAF06_RS24435 () | 137831..138046 | + | 216 | Protein_159 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| EAF06_RS25000 () | 138056..138371 | + | 316 | Protein_160 | type II toxin-antitoxin system VapC family toxin | - |
| EAF06_RS24445 () | 138463..139918 | + | 1456 | Protein_161 | ATP-dependent endonuclease | - |
| EAF06_RS24450 () | 139899..140898 | + | 1000 | Protein_162 | DNA helicase UvrD | - |
| EAF06_RS24455 () | 141146..141850 | - | 705 | Protein_163 | IS1 family transposase | - |
| EAF06_RS24460 () | 141978..142676 | - | 699 | Protein_164 | IS1 family transposase | - |
| EAF06_RS25005 () | 142876..142989 | + | 114 | Protein_165 | IS6 family transposase | - |
| EAF06_RS24465 () | 143070..143296 | + | 227 | Protein_166 | DsbA family protein | - |
| EAF06_RS24470 () | 143286..143792 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| EAF06_RS24475 () | 144028..144786 | + | 759 | Protein_168 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| EAF06_RS24480 () | 145132..146286 | + | 1155 | Protein_169 | FTR1 family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|