MGE detailed information
MGE type: Conjugative plasmid MGE length: 145001 bp
Accession: NZ_CP026934 Location: 1..145001 Organism: Escherichia coli strain CFS3273 Replicon: plasmid pCFS3273-2
Accession: NZ_CP026934 Location: 1..145001 Organism: Escherichia coli strain CFS3273 Replicon: plasmid pCFS3273-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C5F73_RS25915 () | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| C5F73_RS25920 () | 1257..1997 | - | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| C5F73_RS25925 () | 2118..2306 | - | 189 | WP_032141192.1 | hypothetical protein | - |
| C5F73_RS25930 () | 2673..3842 | + | 1170 | WP_001072359.1 | hypothetical protein | - |
| C5F73_RS25935 () | 4068..4243 | - | 176 | Protein_4 | IS3 family transposase | - |
| C5F73_RS25940 () | 4689..4961 | - | 273 | WP_071526560.1 | Major pilu subunit operon regulatory protein PapB | VF |
| C5F73_RS25945 () | 5091..6703 | - | 1613 | Protein_6 | IS66 family transposase ISEc43 | Transposase |
| C5F73_RS25950 () | 6734..7084 | - | 351 | WP_000624688.1 | IS66 family transposase ISEc47 | Transposase |
| C5F73_RS25955 () | 7081..7515 | - | 435 | WP_001309734.1 | IS66 family transposase ISEc43 | Transposase |
| C5F73_RS25960 () | 7846..9816 | + | 1971 | WP_001298664.1 | Hemin receptor | VF |
| C5F73_RS25965 () | 9823..10614 | + | 792 | WP_000977395.1 | DUF4198 domain-containing protein | - |
| C5F73_RS25970 () | 10673..12286 | - | 1614 | WP_001366169.1 | IS66 family transposase ISEc23 | Transposase |
| C5F73_RS25975 () | 12317..12667 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| C5F73_RS25980 () | 12664..13089 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| C5F73_RS25985 () | 13217..13816 | - | 600 | Protein_14 | IS66 family transposase ISEc22 | Transposase |
| C5F73_RS25990 () | 13816..14016 | + | 201 | Protein_15 | IS3 family transposase IS629 | Transposase |
| C5F73_RS25995 () | 14689..15984 | + | 1296 | Protein_16 | group II intron reverse transcriptase/maturase | - |
| C5F73_RS26000 () | 16038..16742 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| C5F73_RS26005 () | 17020..17880 | + | 861 | WP_159373457.1 | Beta-lactamase TEM | ARG |
| C5F73_RS26010 () | 18028..18327 | + | 300 | Protein_19 | hypothetical protein | - |
| C5F73_RS26015 () | 18307..18435 | + | 129 | WP_002210551.1 | hypothetical protein | - |
| C5F73_RS26020 () | 18609..19142 | - | 534 | WP_000731968.1 | Phospholipase D | VF |
| C5F73_RS26025 () | 19142..20137 | - | 996 | WP_000128596.1 | Type IV secretion system protein VirB11 | VF |
| C5F73_RS26030 () | 20179..21339 | - | 1161 | WP_000101711.1 | Protein virB10 | VF |
| C5F73_RS26035 () | 21339..22223 | - | 885 | WP_000735067.1 | Type IV secretion system protein virB9 | VF |
| C5F73_RS26040 () | 22234..22932 | - | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| C5F73_RS26045 () | 22922..23068 | - | 147 | WP_001257173.1 | conjugal transfer protein TraN | - |
| C5F73_RS26050 () | 23151..24191 | - | 1041 | WP_000886022.1 | type IV secretion system protein | - |
| C5F73_RS26055 () | 24283..24987 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| C5F73_RS26060 () | 25147..25497 | - | 351 | WP_024129965.1 | H-NS histone family protein | - |
| C5F73_RS26065 () | 25561..26295 | + | 735 | WP_000033783.1 | Type IV secretion system protein virB1 | VF |
| C5F73_RS26070 () | 26304..26585 | + | 282 | WP_000440698.1 | hypothetical protein | - |
| C5F73_RS26075 () | 26595..26888 | + | 294 | WP_000209137.1 | hypothetical protein | - |
| C5F73_RS26080 () | 26938..27255 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| C5F73_RS26085 () | 27255..29855 | + | 2601 | WP_001200711.1 | Type IV secretion system protein virB4 | VF |
| C5F73_RS26090 () | 29873..30586 | + | 714 | WP_000749362.1 | Type IV secretion system protein virB5 | VF |
| C5F73_RS26095 () | 30594..30857 | + | 264 | WP_159373458.1 | IS6 family transposase IS15 | Transposase |
| C5F73_RS26100 () | 30869..31573 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| C5F73_RS26105 () | 31868..33082 | + | 1215 | WP_001532073.1 | type II site-specific deoxyribonuclease | - |
| C5F73_RS26110 () | 33116..34519 | - | 1404 | WP_072135327.1 | DNA cytosine methyltransferase | - |
| C5F73_RS26115 () | 34643..34915 | + | 273 | Protein_40 | IS1 family transposase IS1X2 | Transposase |
| C5F73_RS26120 () | 34909..35271 | - | 363 | WP_000275181.1 | Transposon Tn10 TetD protein | VF |
| C5F73_RS26125 () | 35359..35952 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| C5F73_RS26130 () | 36065..37270 | - | 1206 | WP_001089064.1 | Tetracycline resistance protein, class B | ARG |
| C5F73_RS26135 () | 37352..37975 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| C5F73_RS26140 () | 37953..38639 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| C5F73_RS26145 () | 38647..39033 | - | 387 | WP_000460651.1 | hypothetical protein | - |
| C5F73_RS26150 () | 39026..39346 | - | 321 | WP_000562370.1 | antibiotic biosynthesis monooxygenase | - |
| C5F73_RS26155 () | 39790..40995 | + | 1206 | WP_000599533.1 | sodium/glutamate symporter | - |
| C5F73_RS26160 () | 41226..41345 | + | 120 | Protein_49 | LysR family transcriptional regulator | - |
| C5F73_RS26165 () | 41361..42569 | - | 1209 | WP_001352368.1 | IS4 family transposase IS10R | Transposase |
| C5F73_RS26170 () | 42855..43658 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| C5F73_RS26175 () | 43658..44494 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| C5F73_RS26180 () | 44830..45645 | + | 816 | WP_000018321.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| C5F73_RS26185 () | 45799..46674 | - | 876 | WP_001201005.1 | acyl-CoA--6-aminopenicillanic acid acyl-transferase | - |
| C5F73_RS26190 () | 46744..49629 | - | 2886 | WP_001138082.1 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| C5F73_RS26195 () | 49755..49862 | + | 108 | Protein_56 | recombinase family protein | - |
| C5F73_RS26200 () | 49915..50619 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| C5F73_RS26205 () | 51205..51549 | + | 345 | WP_000793307.1 | hypothetical protein | - |
| C5F73_RS26210 () | 51725..52303 | - | 579 | Protein_59 | DUF4238 domain-containing protein | - |
| C5F73_RS26215 () | 52340..53155 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| C5F73_RS26220 () | 53370..53642 | + | 273 | WP_000019163.1 | hypothetical protein | - |
| C5F73_RS26225 () | 53623..54831 | + | 1209 | WP_000198533.1 | IS91 family transposase ISSbo1 | Transposase |
| C5F73_RS26230 () | 55003..55182 | - | 180 | Protein_63 | hypothetical protein | - |
| C5F73_RS26235 () | 55534..55788 | + | 255 | WP_000343103.1 | hypothetical protein | - |
| C5F73_RS26240 () | 55788..56378 | + | 591 | WP_000194550.1 | hypothetical protein | - |
| C5F73_RS26245 () | 56396..56743 | - | 348 | WP_001115718.1 | hypothetical protein | - |
| C5F73_RS26250 () | 56828..57109 | - | 282 | WP_000969996.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| C5F73_RS26255 () | 57106..57375 | - | 270 | WP_000079928.1 | hypothetical protein | Antitoxin Detail |
| C5F73_RS26260 () | 58289..59146 | - | 858 | WP_000131010.1 | incFII family plasmid replication initiator RepA | - |
| C5F73_RS26265 () | 59139..59213 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| C5F73_RS26270 () | 59460..59708 | - | 249 | WP_000083835.1 | replication regulatory protein RepA | - |
| C5F73_RS26275 () | 59992..60198 | - | 207 | WP_001553767.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 60185..60246 | + | 62 | NuclAT_2 | - | - |
| - () | 60185..60246 | + | 62 | NuclAT_2 | - | - |
| - () | 60185..60246 | + | 62 | NuclAT_2 | - | - |
| - () | 60185..60246 | + | 62 | NuclAT_2 | - | - |
| C5F73_RS26280 () | 60421..60803 | - | 383 | Protein_73 | hypothetical protein | - |
| C5F73_RS26285 () | 60906..61367 | - | 462 | WP_000760078.1 | thermonuclease family protein | - |
| C5F73_RS26290 () | 62110..62313 | - | 204 | WP_001327131.1 | hypothetical protein | - |
| C5F73_RS26295 () | 62468..63025 | - | 558 | WP_000139312.1 | fertility inhibition protein FinO | - |
| C5F73_RS26300 () | 63128..63988 | - | 861 | WP_000704512.1 | putative protein YcjY | VF |
| C5F73_RS26305 () | 64047..64793 | - | 747 | WP_000205745.1 | conjugal transfer pilus acetylase TraX | - |
| C5F73_RS26310 () | 64813..70083 | - | 5271 | WP_000986969.1 | Multifunctional conjugation protein TraI | Relaxase |
| C5F73_RS26315 () | 70165..70392 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| C5F73_RS26320 () | 70392..70790 | + | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| C5F73_RS26325 () | 70799..72952 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| C5F73_RS26330 () | 73205..73936 | - | 732 | WP_023565183.1 | complement resistance protein TraT | - |
| C5F73_RS26335 () | 73968..74465 | - | 498 | WP_000605859.1 | entry exclusion protein | - |
| C5F73_RS26340 () | 74481..77303 | - | 2823 | WP_001007016.1 | conjugal transfer mating pair stabilization protein TraG | - |
| C5F73_RS26345 () | 77300..78673 | - | 1374 | WP_001517790.1 | conjugal transfer protein TraH | - |
| C5F73_RS26350 () | 78673..79086 | - | 414 | WP_001331260.1 | F-type conjugal transfer protein TrbF | - |
| C5F73_RS26355 () | 79040..79381 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| C5F73_RS26360 () | 79311..79856 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| C5F73_RS26365 () | 79843..80127 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| C5F73_RS26370 () | 80208..80522 | + | 315 | WP_000415566.1 | protein ArtA | - |
| C5F73_RS26375 () | 80524..80871 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| C5F73_RS26380 () | 80887..81630 | - | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| C5F73_RS26385 () | 81623..81880 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| C5F73_RS26390 () | 81907..83715 | - | 1809 | WP_000821840.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| C5F73_RS26395 () | 83712..84350 | - | 639 | WP_000777690.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| C5F73_RS26400 () | 84359..85351 | - | 993 | WP_000830835.1 | conjugal transfer pilus assembly protein TraU | - |
| C5F73_RS26405 () | 85348..85980 | - | 633 | WP_001203750.1 | type-F conjugative transfer system protein TraW | - |
| C5F73_RS26410 () | 85977..86363 | - | 387 | WP_000099693.1 | type-F conjugative transfer system protein TrbI | - |
| C5F73_RS26415 () | 86360..88987 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| C5F73_RS26420 () | 89147..89368 | - | 222 | WP_001278686.1 | conjugal transfer protein TraR | - |
| C5F73_RS26425 () | 89503..90018 | - | 516 | WP_000809885.1 | type IV conjugative transfer system lipoprotein TraV | - |
| C5F73_RS26430 () | 90015..90266 | - | 252 | WP_001038331.1 | conjugal transfer protein TrbG | - |
| C5F73_RS26435 () | 90259..90627 | - | 369 | WP_071526483.1 | DUF2689 domain-containing protein | - |
| C5F73_RS26440 () | 90566..91147 | - | 582 | WP_023565182.1 | conjugal transfer protein TraP | - |
| C5F73_RS26445 () | 91116..92567 | - | 1452 | WP_000146659.1 | conjugal transfer protein TraB | - |
| C5F73_RS26450 () | 92567..93271 | - | 705 | WP_148935590.1 | type-F conjugative transfer system secretin TraK | - |
| C5F73_RS26455 () | 93282..93848 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| C5F73_RS26460 () | 93870..94181 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| C5F73_RS26465 () | 94186..94548 | - | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| C5F73_RS26470 () | 94581..94976 | - | 396 | WP_001366159.1 | conjugal transfer relaxosome protein TraY | - |
| C5F73_RS26475 () | 95075..95764 | - | 690 | WP_000283383.1 | conjugal transfer transcriptional regulator TraJ | - |
| C5F73_RS26480 () | 95951..96334 | - | 384 | WP_001151528.1 | relaxosome protein TraM | - |
| C5F73_RS26485 () | 96655..97257 | + | 603 | WP_000243710.1 | hypothetical protein | VF |
| C5F73_RS26490 () | 97554..98375 | - | 822 | WP_001234423.1 | DUF945 domain-containing protein | - |
| C5F73_RS26495 () | 98495..98692 | - | 198 | WP_052318758.1 | hypothetical protein | - |
| C5F73_RS26500 () | 99702..99860 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 99904..99935 | - | 32 | NuclAT_1 | - | - |
| - () | 99904..99935 | - | 32 | NuclAT_1 | - | - |
| - () | 99904..99935 | - | 32 | NuclAT_1 | - | - |
| - () | 99904..99935 | - | 32 | NuclAT_1 | - | - |
| - () | 101377..101574 | - | 198 | NuclAT_0 | - | - |
| - () | 101377..101574 | - | 198 | NuclAT_0 | - | - |
| - () | 101377..101574 | - | 198 | NuclAT_0 | - | - |
| - () | 101377..101574 | - | 198 | NuclAT_0 | - | - |
| C5F73_RS26510 () | 101386..101574 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| C5F73_RS26515 () | 101586..102305 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| C5F73_RS26520 () | 102302..102736 | - | 435 | WP_000845932.1 | conjugation system SOS inhibitor PsiB | - |
| C5F73_RS26525 () | 102791..104749 | - | 1959 | Protein_122 | ParB/RepB/Spo0J family partition protein | - |
| C5F73_RS26530 () | 104815..105048 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| C5F73_RS26535 () | 105111..105563 | - | 453 | WP_000290843.1 | single-stranded DNA-binding protein | - |
| C5F73_RS26540 () | 105589..105795 | - | 207 | WP_024190028.1 | hypothetical protein | - |
| C5F73_RS26545 () | 106206..106415 | - | 210 | WP_021512934.1 | hypothetical protein | - |
| C5F73_RS26550 () | 106441..107004 | - | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| C5F73_RS26555 () | 107052..108413 | - | 1362 | WP_000170724.1 | DUF3560 domain-containing protein | - |
| C5F73_RS26560 () | 108465..108695 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| C5F73_RS26565 () | 109209..109457 | + | 249 | WP_071526484.1 | hypothetical protein | - |
| C5F73_RS26570 () | 109730..109921 | - | 192 | WP_001027519.1 | hypothetical protein | - |
| C5F73_RS26575 () | 109918..110340 | - | 423 | WP_000271751.1 | DUF1380 family protein | - |
| C5F73_RS26580 () | 110387..110689 | - | 303 | WP_077632858.1 | antirestriction protein | - |
| C5F73_RS26585 () | 111229..111999 | - | 771 | WP_001006209.1 | hypothetical protein | - |
| C5F73_RS26590 () | 112044..112478 | - | 435 | WP_000274502.1 | DUF1380 family protein | - |
| C5F73_RS26595 () | 112492..112713 | - | 222 | WP_001104879.1 | hypothetical protein | - |
| C5F73_RS26600 () | 112714..113397 | - | 684 | WP_000085871.1 | DNA methylase | - |
| C5F73_RS26605 () | 113473..113784 | - | 312 | WP_032141194.1 | hypothetical protein | - |
| C5F73_RS26610 () | 113781..114683 | - | 903 | WP_077632859.1 | DUF1281 domain-containing protein | - |
| C5F73_RS26615 () | 115335..116306 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| C5F73_RS26620 () | 116306..117472 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| C5F73_RS26625 () | 118060..118815 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| C5F73_RS26630 () | 119537..120343 | - | 807 | WP_000016970.1 | site-specific integrase | - |
| C5F73_RS26635 () | 120344..120649 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| C5F73_RS26640 () | 120651..120869 | - | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| C5F73_RS26645 () | 121497..121727 | + | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| C5F73_RS26650 () | 121724..122140 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| C5F73_RS26655 () | 122215..123780 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| C5F73_RS26660 () | 123765..124787 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| C5F73_RS26665 () | 125041..125727 | - | 687 | Protein_150 | IS1 family transposase IS1S | Transposase |
| C5F73_RS26675 () | 127282..129483 | - | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| C5F73_RS26680 () | 129565..130842 | - | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| C5F73_RS26685 () | 130839..132581 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| C5F73_RS26690 () | 132581..133528 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| C5F73_RS26695 () | 133529..135253 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| C5F73_RS26700 () | 135389..136582 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| C5F73_RS26705 () | 136962..137342 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| C5F73_RS26710 () | 137683..138096 | - | 414 | Protein_159 | phosphopyruvate hydratase | - |
| C5F73_RS26715 () | 138094..138351 | + | 258 | Protein_160 | Tn3 family transposase | - |
| C5F73_RS26720 () | 138585..139442 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| C5F73_RS26725 () | 139439..140296 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| C5F73_RS26730 () | 140293..141120 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| C5F73_RS26735 () | 141120..142034 | - | 915 | WP_000949005.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| C5F73_RS26740 () | 142390..143076 | + | 687 | Protein_165 | IS1 family transposase IS1S | Transposase |
| C5F73_RS26745 () | 143256..143769 | - | 514 | Protein_166 | DUF4113 domain-containing protein | - |
| C5F73_RS26750 () | 143830..143934 | - | 105 | Protein_167 | AAA family ATPase | - |
| C5F73_RS26755 () | 143936..144259 | - | 324 | Protein_168 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|