MGE detailed information
MGE type: Conjugative plasmid MGE length: 129225 bp
Accession: NZ_CP026930 Location: 1..129225 Organism: Escherichia coli strain CFS3246 Replicon: plasmid pCFS3246-1
Accession: NZ_CP026930 Location: 1..129225 Organism: Escherichia coli strain CFS3246 Replicon: plasmid pCFS3246-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C4962_RS23125 () | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| C4962_RS23130 () | 1257..1997 | - | 741 | WP_001066937.1 | site-specific integrase | - |
| C4962_RS23135 () | 2118..2279 | - | 162 | WP_063074630.1 | hypothetical protein | - |
| C4962_RS23140 () | 2332..2682 | + | 351 | WP_032215349.1 | YgiW/YdeI family stress tolerance OB fold protein | - |
| C4962_RS23145 () | 2920..3795 | + | 876 | WP_000879139.1 | CDF family zinc transporter ZitB | - |
| C4962_RS23150 () | 4295..4537 | + | 243 | WP_000470771.1 | hypothetical protein | - |
| C4962_RS23155 () | 4605..4880 | - | 276 | WP_000662184.1 | hypothetical protein | - |
| C4962_RS23165 () | 6136..6372 | + | 237 | WP_032215364.1 | Major pilu subunit operon regulatory protein PapB | VF |
| C4962_RS23170 () | 6529..7062 | + | 534 | WP_032235482.1 | Major MR/P fimbria protein | VF |
| C4962_RS23175 () | 7140..7948 | + | 809 | Protein_9 | fimbria/pilus outer membrane usher protein | - |
| C4962_RS23180 () | 7948..8645 | - | 698 | Protein_10 | IS1 family transposase | - |
| C4962_RS23185 () | 9127..9657 | - | 531 | WP_000348879.1 | GNAT family N-acetyltransferase | Toxin Detail |
| C4962_RS23190 () | 9661..9930 | - | 270 | WP_000114669.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| C4962_RS23195 () | 10123..10619 | - | 497 | Protein_13 | tyrosine-type recombinase/integrase | - |
| C4962_RS23200 () | 10780..11307 | - | 528 | WP_000592915.1 | hypothetical protein | - |
| C4962_RS23205 () | 11300..11824 | - | 525 | WP_000737845.1 | type 1 fimbrial protein | - |
| C4962_RS23210 () | 11824..12825 | - | 1002 | WP_000792596.1 | protein FanF | - |
| C4962_RS23215 () | 12825..13511 | - | 687 | WP_001031857.1 | Chaperone protein FaeE | VF |
| C4962_RS23220 () | 13504..15888 | - | 2385 | WP_001375165.1 | Outer membrane usher protein YraJ | VF |
| C4962_RS23225 () | 15922..16467 | - | 546 | WP_089508147.1 | hypothetical protein | VF |
| C4962_RS23230 () | 16610..16870 | - | 261 | WP_032215356.1 | Major pilu subunit operon regulatory protein PapB | VF |
| C4962_RS23235 () | 16983..17264 | - | 282 | WP_001375145.1 | Major pilu subunit operon regulatory protein PapB | VF |
| C4962_RS23240 () | 17710..19064 | - | 1355 | Protein_22 | IS66 family transposase ISSgsp1 | Transposase |
| C4962_RS23245 () | 19270..19458 | - | 189 | Protein_23 | IS66 family transposase ISEc8 | Transposase |
| C4962_RS23250 () | 19508..19855 | - | 348 | WP_000612552.1 | IS66 family transposase ISKpn24 | Transposase |
| C4962_RS23255 () | 19881..20777 | - | 897 | Protein_25 | IS3 family transposase ISEhe3 | Transposase |
| C4962_RS23260 () | 20787..21938 | - | 1152 | WP_159373759.1 | IS30 family transposase IS30D | Transposase |
| C4962_RS23270 () | 22003..22428 | + | 426 | Protein_27 | IS3 family transposase IS911 | Transposase |
| C4962_RS23280 () | 23100..24608 | + | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| C4962_RS23285 () | 24689..25156 | + | 468 | Protein_29 | IS3 family transposase IS911 | Transposase |
| C4962_RS23290 () | 25191..26204 | + | 1014 | Protein_30 | IS21 family transposase IS21 | Transposase |
| C4962_RS23295 () | 26204..27001 | + | 798 | WP_032235557.1 | IS21 family transposase IS21 | Transposase |
| C4962_RS23300 () | 27067..27453 | - | 387 | Protein_32 | IS66 family transposase ISCro1 | Transposase |
| C4962_RS23305 () | 27722..28419 | + | 698 | Protein_33 | IS1-like element IS1A family transposase | - |
| C4962_RS23310 () | 28523..28741 | - | 219 | WP_001353651.1 | Heat-stable enterotoxin ST-IA/ST-P | VF |
| C4962_RS23315 () | 28976..29673 | - | 698 | Protein_35 | IS1-like element IS1A family transposase | - |
| C4962_RS23320 () | 30130..30450 | - | 321 | Protein_36 | transposase | - |
| C4962_RS23325 () | 30664..31422 | + | 759 | WP_001257942.1 | hypothetical protein | VF |
| C4962_RS23330 () | 32301..33158 | - | 858 | WP_000130970.1 | incFII family plasmid replication initiator RepA | - |
| C4962_RS23335 () | 33151..33225 | - | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| C4962_RS23340 () | 33471..33719 | - | 249 | WP_000083838.1 | replication regulatory protein RepA | - |
| C4962_RS23345 () | 34003..34152 | - | 150 | WP_001367749.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 34196..34257 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 34196..34257 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 34196..34257 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 34196..34257 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| C4962_RS24445 () | 34516..34758 | - | 243 | WP_000504693.1 | hypothetical protein | - |
| C4962_RS23350 () | 34837..35534 | + | 698 | Protein_43 | IS1-like element IS1A family transposase | - |
| C4962_RS23355 () | 35759..36436 | + | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| C4962_RS23360 () | 36436..36783 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| C4962_RS23365 () | 36803..38374 | + | 1572 | WP_000381395.1 | IS66 family transposase ISCro1 | Transposase |
| C4962_RS23370 () | 39182..39385 | - | 204 | WP_001375146.1 | hypothetical protein | - |
| C4962_RS23375 () | 39540..40097 | - | 558 | WP_000139319.1 | fertility inhibition protein FinO | - |
| C4962_RS23380 () | 40200..41060 | - | 861 | WP_000868986.1 | putative protein YcjY | VF |
| C4962_RS23385 () | 41119..41865 | - | 747 | WP_000205750.1 | conjugal transfer pilus acetylase TraX | - |
| C4962_RS23390 () | 41885..46576 | - | 4692 | Protein_51 | Multifunctional conjugation protein TraI | Relaxase |
| C4962_RS23395 () | 46524..49409 | - | 2886 | WP_001138082.1 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| C4962_RS23400 () | 49535..49996 | + | 462 | Protein_53 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| C4962_RS23405 () | 50050..50754 | - | 705 | WP_001067845.1 | IS6 family transposase IS26 | Transposase |
| C4962_RS23410 () | 50817..51041 | - | 225 | Protein_55 | Tn3 family transposase TnpA_Tn3 | Transposase |
| C4962_RS23415 () | 51205..51762 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| C4962_RS23420 () | 51869..52573 | + | 705 | WP_001067845.1 | IS6 family transposase IS26 | Transposase |
| C4962_RS23425 () | 52666..53013 | - | 348 | WP_000142451.1 | hypothetical protein | - |
| C4962_RS23430 () | 53142..53477 | + | 336 | WP_001080730.1 | colicin 1A immunity protein | - |
| C4962_RS23435 () | 53499..53858 | - | 360 | WP_085452786.1 | colicin | - |
| C4962_RS23440 () | 53932..54629 | + | 698 | Protein_61 | IS1 family transposase | - |
| C4962_RS23445 () | 54679..54954 | - | 276 | WP_000421257.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| C4962_RS23450 () | 54954..55238 | - | 285 | WP_001178089.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| C4962_RS23455 () | 55638..55851 | - | 214 | Protein_64 | transposase | - |
| C4962_RS23460 () | 56181..57041 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| C4962_RS23465 () | 57241..57945 | - | 705 | WP_001067845.1 | IS6 family transposase IS26 | Transposase |
| C4962_RS23475 () | 58233..59362 | + | 1130 | WP_085959879.1 | IS3 family transposase IS1133 | Transposase |
| C4962_RS23480 () | 59469..60272 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| C4962_RS23485 () | 60272..61108 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| C4962_RS23490 () | 61012..61215 | + | 204 | Protein_70 | mobilization protein (MobL-like) | - |
| C4962_RS23495 () | 61213..61883 | - | 671 | Protein_71 | Multifunctional conjugation protein TraI | Relaxase |
| C4962_RS23500 () | 61965..62192 | + | 228 | WP_000450532.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| C4962_RS23505 () | 62192..62590 | + | 399 | WP_000911314.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| C4962_RS23510 () | 62599..64752 | - | 2154 | WP_001375140.1 | type IV conjugative transfer system coupling protein TraD | - |
| C4962_RS23515 () | 65005..65736 | - | 732 | WP_000850426.1 | complement resistance protein TraT | - |
| C4962_RS23520 () | 65750..66259 | - | 510 | WP_000628103.1 | conjugal transfer entry exclusion protein TraS | - |
| C4962_RS23525 () | 66256..69081 | - | 2826 | WP_032234620.1 | conjugal transfer mating pair stabilization protein TraG | - |
| C4962_RS23530 () | 69078..70451 | - | 1374 | WP_000488446.1 | conjugal transfer protein TraH | - |
| C4962_RS23535 () | 70451..70864 | - | 414 | WP_071532141.1 | F-type conjugal transfer protein TrbF | - |
| C4962_RS23540 () | 70818..71159 | - | 342 | WP_012477176.1 | P-type conjugative transfer protein TrbJ | - |
| C4962_RS23545 () | 71089..71634 | - | 546 | WP_000059835.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| C4962_RS23550 () | 71621..71905 | - | 285 | WP_000624108.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| C4962_RS23555 () | 71986..72300 | + | 315 | WP_000415566.1 | protein ArtA | - |
| C4962_RS23560 () | 72302..72649 | - | 348 | WP_001287908.1 | conjugal transfer protein TrbA | - |
| C4962_RS23565 () | 72665..73408 | - | 744 | WP_001030388.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| C4962_RS23570 () | 73401..73616 | - | 216 | WP_089508142.1 | conjugal transfer protein TrbE | - |
| C4962_RS24450 () | 74920..74994 | - | 75 | Protein_88 | conjugal transfer protein TrbE | - |
| C4962_RS23580 () | 75021..76829 | - | 1809 | WP_000821828.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| C4962_RS23585 () | 76826..77464 | - | 639 | WP_000777698.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| C4962_RS23590 () | 77473..78465 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| C4962_RS23595 () | 78462..79094 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| C4962_RS23600 () | 79091..79477 | - | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| C4962_RS23605 () | 79474..82101 | - | 2628 | WP_001064244.1 | type IV secretion system protein TraC | - |
| C4962_RS23610 () | 82261..82482 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| C4962_RS23615 () | 82617..83132 | - | 516 | WP_000809906.1 | type IV conjugative transfer system lipoprotein TraV | - |
| C4962_RS23620 () | 83129..83380 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| C4962_RS23625 () | 83392..83622 | - | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| C4962_RS23630 () | 83576..84166 | - | 591 | WP_000002790.1 | conjugal transfer protein TraP | - |
| C4962_RS23635 () | 84156..85583 | - | 1428 | WP_000146689.1 | conjugal transfer protein TraB | - |
| C4962_RS23640 () | 85583..86311 | - | 729 | WP_001230813.1 | type-F conjugative transfer system secretin TraK | - |
| C4962_RS23645 () | 86298..86864 | - | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| C4962_RS23650 () | 86886..87197 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| C4962_RS23655 () | 87212..87577 | - | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| C4962_RS23660 () | 87620..87835 | - | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| C4962_RS23665 () | 87971..88618 | - | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| C4962_RS23670 () | 88809..89192 | - | 384 | WP_001063020.1 | relaxosome protein TraM | - |
| C4962_RS23675 () | 89544..90134 | + | 591 | WP_165835419.1 | hypothetical protein | VF |
| C4962_RS23680 () | 90431..91252 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| C4962_RS23685 () | 91371..91658 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| C4962_RS23690 () | 91655..91858 | - | 204 | WP_077756203.1 | hypothetical protein | - |
| C4962_RS23695 () | 92236..92394 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 92438..92662 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 92438..92662 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 92438..92662 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 92438..92662 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| C4962_RS23700 () | 92474..92662 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| C4962_RS23705 () | 92674..93393 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| C4962_RS23710 () | 93390..93824 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| C4962_RS23715 () | 93879..95837 | - | 1959 | WP_001775124.1 | ParB/RepB/Spo0J family partition protein | - |
| C4962_RS23720 () | 95903..96136 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| C4962_RS23725 () | 96199..96738 | - | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| C4962_RS23730 () | 96972..97160 | - | 189 | WP_032149780.1 | hypothetical protein | - |
| C4962_RS23735 () | 97381..97572 | - | 192 | WP_046952204.1 | hypothetical protein | - |
| C4962_RS23740 () | 97598..98161 | - | 564 | WP_046952203.1 | class I SAM-dependent methyltransferase | - |
| C4962_RS23745 () | 98208..99569 | - | 1362 | WP_046952202.1 | DUF3560 domain-containing protein | - |
| C4962_RS23750 () | 99621..99851 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| C4962_RS23755 () | 100365..100613 | + | 249 | WP_071556315.1 | hypothetical protein | - |
| C4962_RS23760 () | 100886..101077 | - | 192 | WP_001027519.1 | hypothetical protein | - |
| C4962_RS23765 () | 101074..101496 | - | 423 | WP_000271751.1 | DUF1380 family protein | - |
| C4962_RS23770 () | 101543..101845 | - | 303 | WP_077632858.1 | antirestriction protein | - |
| C4962_RS23775 () | 101941..102512 | - | 572 | Protein_128 | DUF1472 domain-containing protein | - |
| C4962_RS23780 () | 102397..103161 | - | 765 | Protein_129 | hypothetical protein | - |
| C4962_RS23785 () | 103212..103646 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| C4962_RS23790 () | 103660..103881 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| C4962_RS23795 () | 103882..104565 | - | 684 | WP_001775017.1 | DNA methylase | - |
| C4962_RS23800 () | 104642..104935 | - | 294 | WP_063074623.1 | hypothetical protein | - |
| C4962_RS23805 () | 105082..106044 | + | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| C4962_RS23810 () | 106047..106397 | + | 351 | WP_000361384.1 | plasmid partitioning/stability family protein | - |
| C4962_RS23815 () | 106548..107060 | - | 513 | WP_001027529.1 | hypothetical protein | - |
| C4962_RS23820 () | 107501..109036 | + | 1536 | WP_001282376.1 | pore-forming bacteriocin colicin B | - |
| C4962_RS23825 () | 109054..109581 | - | 528 | WP_000203268.1 | colicin B immunity protein | - |
| C4962_RS23830 () | 109824..110639 | + | 816 | WP_000449473.1 | lipid II-degrading bacteriocin colicin M | - |
| C4962_RS23835 () | 110689..111042 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| C4962_RS23840 () | 111215..111997 | - | 783 | WP_001164199.1 | site-specific integrase | - |
| C4962_RS24455 () | 111999..112241 | - | 243 | WP_167738958.1 | hypothetical protein | - |
| C4962_RS24460 () | 112163..112411 | - | 249 | WP_167738957.1 | hypothetical protein | - |
| C4962_RS23850 () | 113351..114028 | + | 678 | WP_001299364.1 | IS66 family transposase ISCro1 | Transposase |
| C4962_RS23855 () | 114028..114375 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| C4962_RS23860 () | 114395..115966 | + | 1572 | WP_000381395.1 | IS66 family transposase ISCro1 | Transposase |
| C4962_RS23865 () | 116231..118285 | - | 2055 | WP_089508174.1 | hypothetical protein | - |
| C4962_RS23875 () | 120958..121188 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| C4962_RS23880 () | 121185..121601 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| C4962_RS23885 () | 121763..123901 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| C4962_RS23890 () | 124255..124512 | + | 258 | WP_000371887.1 | hypothetical protein | - |
| C4962_RS23895 () | 124512..125102 | + | 591 | WP_000194548.1 | hypothetical protein | - |
| C4962_RS23900 () | 125120..125467 | - | 348 | WP_000142443.1 | hypothetical protein | - |
| C4962_RS23905 () | 125596..125931 | + | 336 | WP_057698418.1 | colicin transporter | - |
| C4962_RS23910 () | 125953..126438 | - | 486 | Protein_156 | hypothetical protein | - |
| C4962_RS23915 () | 126377..126867 | - | 491 | Protein_157 | IS3 family transposase ISEcl1 | Transposase |
| C4962_RS23920 () | 126980..128041 | - | 1062 | WP_032235339.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|