MGE detailed information

MGE type: Conjugative plasmid        MGE length: 181324 bp
Accession: NZ_CP023845        Location: 1..181324         Organism: Escherichia coli strain 4/1-1       Replicon: plasmid p4_1_1.1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRT35_RS25665 () 1..447 + 447 Protein_1 incFII family plasmid replication initiator RepA -
CRT35_RS25670 () 393..875 - 483 Protein_2 VENN motif pre-toxin domain-containing protein -
CRT35_RS25675 () 1768..2988 + 1221 WP_000410951.1 arginine deiminase -
CRT35_RS25680 () 2999..3910 + 912 WP_000440183.1 carbamate kinase -
CRT35_RS25685 () 3995..4999 + 1005 WP_000154544.1 Ornithine carbamoyltransferase VF
CRT35_RS25690 () 5047..6450 + 1404 WP_000514417.1 YfcC family protein -
CRT35_RS25695 () 6531..7010 + 480 WP_001496175.1 ArgR family transcriptional regulator -
CRT35_RS25700 () 7074..7415 - 342 Protein_8 transposase -
CRT35_RS25705 () 7367..7588 - 222 WP_000080217.1 IS66 family transposase ISEc47 Transposase
CRT35_RS25710 () 7619..7969 - 351 WP_000624725.1 IS66 family transposase ISEc47 Transposase
CRT35_RS25715 () 7966..8328 - 363 WP_059330006.1 IS66 family transposase ISEc23 Transposase
CRT35_RS25720 () 8437..9130 - 694 Protein_12 IS1 family transposase IS1A Transposase
CRT35_RS25725 () 9163..9741 + 579 WP_032147503.1 DUF2726 domain-containing protein -
CRT35_RS25730 () 10154..10507 - 354 WP_000005489.1 hypothetical protein -
CRT35_RS25735 () 10979..12001 - 1023 WP_000156883.1 IS110 family transposase ISSm1 Transposase
CRT35_RS25745 () 12406..12663 + 258 WP_000083821.1 replication regulatory protein RepA -
CRT35_RS25755 () 12899..12973 + 75 WP_001365705.1 RepA leader peptide Tap -
CRT35_RS25760 () 12966..13823 + 858 WP_124850296.1 incFII family plasmid replication initiator RepA -
CRT35_RS25770 () 14762..15415 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
CRT35_RS25775 () 15508..15765 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
CRT35_RS25780 () 15698..16099 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
CRT35_RS25785 () 16236..19133 - 2898 WP_001553819.1 Tn3 family transposase TnpA_Tn5403 Transposase
CRT35_RS25790 () 19228..19833 + 606 WP_000509965.1 Tn3 family transposase TnpR_Tn5403 Transposase
CRT35_RS25795 () 19857..20606 - 750 Protein_24 Tn3 family transposase TnpA_TnAs1 Transposase
CRT35_RS25800 () 20595..21002 + 408 WP_001214976.1 cysteine hydrolase -
CRT35_RS25805 () 21140..22024 + 885 WP_000058717.1 EamA family transporter -
CRT35_RS25810 () 22056..23255 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
CRT35_RS25815 () 23361..24011 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
CRT35_RS25820 () 24043..24285 - 243 WP_032140899.1 hypothetical protein -
CRT35_RS25825 () 24327..25841 - 1515 Protein_30 Tn3 family transposase TnpA_TnAs1 Transposase
CRT35_RS25830 () 25907..26611 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CRT35_RS25835 () 26755..27309 + 555 WP_063840321.1 Aminoglycoside N(6')-acetyltransferase type 1 ARG
CRT35_RS25840 () 27440..28270 + 831 WP_001334766.1 Beta-lactamase OXA-1 ARG
CRT35_RS25845 () 28408..28848 + 441 Protein_34 CatB-related O-acetyltransferase -
CRT35_RS25850 () 28902..29606 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CRT35_RS25855 () 29671..31914 - 2244 Protein_36 Tn3 family transposase TnpA_Tn3 Transposase
CRT35_RS25860 () 31928..32260 + 333 WP_001393253.1 WbuC family cupin fold metalloprotein -
CRT35_RS25865 () 32307..33182 - 876 WP_000239590.1 Beta-lactamase CTX-M-1 ARG
CRT35_RS25870 () 33438..34700 - 1263 WP_000608644.1 IS1380 family transposase ISEcp1 Transposase
CRT35_RS25875 () 34906..35100 - 195 Protein_40 Tn3 family transposase TnpA_Tn3 Transposase
CRT35_RS25880 () 35264..35821 + 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
CRT35_RS25885 () 36004..36864 + 861 WP_000027057.1 Beta-lactamase TEM ARG
CRT35_RS25890 () 37025..37522 + 498 Protein_43 mercuric reductase -
CRT35_RS25895 () 37540..37902 + 363 WP_001277456.1 mercury resistance co-regulator MerD -
CRT35_RS25900 () 37899..38135 + 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
CRT35_RS25905 () 38171..38839 + 669 WP_001300294.1 putative signaling protein VF
CRT35_RS25915 () 38914..40164 + 1251 Protein_47 transposase -
CRT35_RS25920 () 40229..40933 + 705 WP_001067834.1 IS6 family transposase IS26 Transposase
CRT35_RS25925 () 41123..41938 - 816 WP_000018329.1 Aminoglycoside 3'-phosphotransferase ARG
CRT35_RS25930 () 42089..42793 + 705 WP_001067834.1 IS6 family transposase IS26 Transposase
CRT35_RS25940 () 42915..43820 + 906 WP_000219391.1 hypothetical protein ARG
CRT35_RS25945 () 43817..45055 + 1239 WP_000004159.1 MFS transporter -
CRT35_RS25950 () 45055..45639 + 585 WP_001137892.1 TetR family transcriptional regulator -
CRT35_RS25965 () 46132..46896 - 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
CRT35_RS25975 () 47123..47428 - 306 WP_000130000.1 hypothetical protein Relaxase
CRT35_RS25980 () 47439..48644 - 1206 WP_000184001.1 chromate efflux transporter -
CRT35_RS25985 () 48800..49003 - 204 WP_000376616.1 hypothetical protein -
CRT35_RS25995 () 49131..49970 - 840 WP_000259031.1 Dihydropteroate synthase ARG
CRT35_RS26000 () 49964..50311 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
CRT35_RS26005 () 50475..51266 - 792 WP_001206356.1 Streptomycin 3''-adenylyltransferase ARG
CRT35_RS26010 () 51272..51562 - 291 WP_001336345.1 DUF1010 domain-containing protein -
CRT35_RS26015 () 51674..52171 - 498 WP_001083725.1 Dihydrofolate reductase ARG
CRT35_RS26020 () 52316..53257 + 942 WP_033549837.1 IS91 family transposase ISAzo26 Transposase
CRT35_RS26025 () 53304..54008 + 705 WP_001067834.1 IS6 family transposase IS26 Transposase
CRT35_RS26030 () 54066..54596 - 531 Protein_65 histidine-type phosphatase -
CRT35_RS26035 () 54718..55203 - 486 WP_000874189.1 hypothetical protein -
CRT35_RS26040 () 55228..55713 - 486 WP_001267177.1 TlpA family protein disulfide reductase -
CRT35_RS26045 () 55700..56395 - 696 WP_000117262.1 Lipoprotein-releasing system ATP-binding protein LolD VF
CRT35_RS26050 () 56400..57530 - 1131 WP_000729220.1 ABC transporter permease -
CRT35_RS26055 () 57520..58803 - 1284 WP_000964653.1 ABC transporter permease -
CRT35_RS26060 () 58806..60185 - 1380 WP_000119836.1 DUF2318 domain-containing protein -
CRT35_RS26065 () 60289..60816 - 528 WP_000178050.1 iron transporter -
CRT35_RS26070 () 60857..62743 - 1887 WP_000118029.1 FTR1 family iron permease -
CRT35_RS26080 () 63090..63905 - 816 WP_012372823.1 Na(+)-translocating NADH-quinone reductase subunit C -
CRT35_RS26085 () 64088..64594 - 507 WP_000949452.1 protein disulfide oxidoreductase -
CRT35_RS26090 () 64584..64742 - 159 WP_000449408.1 DsbA family protein -
CRT35_RS27450 () 64892..65005 - 114 Protein_77 IS6 family transposase -
CRT35_RS26100 () 65096..65947 + 852 Protein_78 IS4 family transposase IS10R Transposase
CRT35_RS26110 () 66000..66704 - 705 WP_001067834.1 IS6 family transposase IS26 Transposase
CRT35_RS26115 () 66729..67450 + 722 Protein_80 IS3 family transposase IS629 Transposase
CRT35_RS26125 () 68123..69631 + 1509 WP_001189123.1 group II intron reverse transcriptase/maturase -
CRT35_RS26130 () 69721..70195 + 475 Protein_82 IS3 family transposase IS629 Transposase
CRT35_RS26135 () 70217..70450 + 234 Protein_83 Tn3 family transposase ISPsy39 Transposase
CRT35_RS26140 () 70527..70835 + 309 Protein_84 IS4 family transposase ISEc13 Transposase
CRT35_RS26145 () 70894..72204 - 1311 WP_000476108.1 ABC transporter substrate-binding protein -
CRT35_RS26150 () 72197..73270 - 1074 WP_033549814.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC VF
CRT35_RS26155 () 73276..74100 - 825 WP_000922702.1 phosphodiesterase -
CRT35_RS26160 () 74111..74998 - 888 WP_001271561.1 carbohydrate ABC transporter permease -
CRT35_RS26165 () 74988..75866 - 879 WP_000338039.1 sugar ABC transporter permease -
CRT35_RS26170 () 75997..76437 - 441 Protein_90 zinc-binding dehydrogenase -
CRT35_RS26175 () 76411..76605 + 195 WP_000796505.1 hypothetical protein -
CRT35_RS26180 () 76838..77728 + 891 WP_001077068.1 dihydrodipicolinate synthase family protein -
CRT35_RS26185 () 77753..78133 + 381 WP_000710783.1 Rid family detoxifying hydrolase -
CRT35_RS26190 () 78166..79131 + 966 WP_001022265.1 2-keto-3-deoxygluconate transporter -
CRT35_RS26195 () 79177..79929 - 753 WP_000562172.1 IclR family transcriptional regulator -
CRT35_RS26200 () 80534..80818 + 285 WP_001387467.1 ribbon-helix-helix domain-containing protein Antitoxin Detail
CRT35_RS26205 () 80818..81093 + 276 WP_000421272.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
CRT35_RS26210 () 81199..81492 + 294 WP_001105060.1 hypothetical protein -
CRT35_RS26215 () 81527..81655 - 129 Protein_99 IS481 family transposase -
CRT35_RS26220 () 81688..82857 - 1170 WP_001072355.1 hypothetical protein -
CRT35_RS26230 () 83350..83657 + 308 Protein_101 type II toxin-antitoxin system ParD family antitoxin -
CRT35_RS26240 () 84000..84182 + 183 WP_042065278.1 hypothetical protein -
CRT35_RS26245 () 84303..85043 + 741 WP_001066942.1 tyrosine-type recombinase/integrase -
CRT35_RS26250 () 85328..86305 - 978 WP_000361612.1 RepB family plasmid replication initiator protein -
CRT35_RS27455 () 87426..87821 + 396 WP_175188304.1 hypothetical protein -
CRT35_RS26265 () 88308..89005 + 698 Protein_106 IS1 family transposase IS1R Transposase
CRT35_RS26270 () 89021..89350 + 330 Protein_107 TOBE domain-containing protein -
CRT35_RS26275 () 89459..90391 - 933 WP_000081352.1 homocysteine S-methyltransferase -
CRT35_RS26280 () 90378..91781 - 1404 WP_001373486.1 S-methylmethionine permease -
CRT35_RS26285 () 91989..93005 + 1017 WP_012372828.1 IS5 family transposase IS5D Transposase
CRT35_RS26290 () 93233..93550 + 318 WP_001513659.1 hypothetical protein -
CRT35_RS26295 () 93500..93913 - 414 Protein_112 IS3 family transposase ISLad1 Transposase
CRT35_RS26300 () 93837..94196 - 360 WP_001513660.1 hypothetical protein -
CRT35_RS26305 () 94224..94403 - 180 WP_001513661.1 hypothetical protein -
CRT35_RS26310 () 94408..94788 - 381 WP_001216034.1 type II toxin-antitoxin system death-on-curing family toxin Toxin Detail
CRT35_RS26315 () 94788..95009 - 222 WP_001190712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
CRT35_RS26320 () 95192..96748 + 1557 WP_001553856.1 type I restriction-modification system subunit M -
CRT35_RS26325 () 96745..98016 + 1272 WP_048266692.1 restriction endonuclease subunit S -
CRT35_RS26330 () 98138..101254 + 3117 WP_001553854.1 HsdR family type I site-specific deoxyribonuclease -
CRT35_RS26335 () 101468..102165 + 698 Protein_120 IS1 family transposase IS1G Transposase
CRT35_RS26340 () 102302..103234 - 933 WP_000991832.1 hypothetical protein -
CRT35_RS26345 () 103238..104233 - 996 WP_000246636.1 hypothetical protein -
CRT35_RS26350 () 104698..106836 + 2139 WP_000350635.1 AAA family ATPase -
CRT35_RS26355 () 106998..107414 - 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
CRT35_RS26360 () 107411..107641 - 231 WP_001261287.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
CRT35_RS26370 () 107948..111067 + 3120 WP_001553851.1 hypothetical protein -
CRT35_RS26375 () 111330..112463 + 1134 WP_000545983.1 DUF3800 domain-containing protein -
CRT35_RS26380 () 112483..112767 + 285 WP_000642771.1 hypothetical protein -
CRT35_RS26385 () 112764..112961 - 198 WP_000215657.1 hypothetical protein -
CRT35_RS26390 () 113595..113813 + 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
CRT35_RS26395 () 113815..114120 + 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
CRT35_RS26400 () 114121..114927 + 807 WP_000016982.1 site-specific integrase -
CRT35_RS26405 () 115701..116456 + 756 WP_000852146.1 replication initiation protein RepE -
CRT35_RS26410 () 117044..118210 + 1167 WP_000772446.1 Sporulation initiation inhibitor protein Soj VF
CRT35_RS26415 () 118210..119181 + 972 WP_000817036.1 ParB/RepB/Spo0J family plasmid partition protein -
CRT35_RS26430 () 120048..120950 + 903 WP_001348615.1 DUF1281 domain-containing protein -
CRT35_RS26435 () 120954..121258 + 305 Protein_137 hypothetical protein -
CRT35_RS26440 () 121335..122018 + 684 WP_000086185.1 DNA methylase -
CRT35_RS26445 () 122019..122240 + 222 WP_001104873.1 hypothetical protein -
CRT35_RS26450 () 122254..122688 + 435 WP_000274437.1 DUF1380 family protein -
CRT35_RS26455 () 122739..123515 + 777 WP_001753849.1 hypothetical protein -
CRT35_RS26465 () 124055..124357 + 303 WP_001671341.1 antirestriction protein -
CRT35_RS26470 () 124404..124826 + 423 WP_000271753.1 DUF1380 family protein -
CRT35_RS26475 () 124823..125014 + 192 WP_001027516.1 hypothetical protein -
CRT35_RS26485 () 126049..126279 + 231 WP_000218642.1 hypothetical protein -
CRT35_RS26490 () 126331..127692 + 1362 WP_000170714.1 DUF3560 domain-containing protein -
CRT35_RS26495 () 127740..128303 + 564 WP_001348621.1 class I SAM-dependent methyltransferase -
CRT35_RS26500 () 128329..128547 + 219 WP_001496291.1 hypothetical protein -
CRT35_RS26525 () 129648..130217 - 570 WP_089634947.1 hypothetical protein -
CRT35_RS26535 () 131521..132279 + 759 Protein_151 site-specific integrase -
CRT35_RS26540 () 132437..133447 + 1011 WP_000053332.1 substrate-binding domain-containing protein -
CRT35_RS26545 () 133543..135669 + 2127 WP_000253905.1 alpha-galactosidase -
CRT35_RS26550 () 135732..137009 + 1278 WP_001083369.1 MFS transporter -
CRT35_RS26555 () 137006..138439 + 1434 WP_024170639.1 glycoside hydrolase family 32 protein -
CRT35_RS26560 () 138634..140028 + 1395 WP_001037799.1 carbohydrate porin -
CRT35_RS26570 () 140274..140378 - 105 Protein_157 thiosulfate reductase cytochrome B subunit -
CRT35_RS26575 () 140435..141128 + 694 Protein_158 IS1 family transposase IS1A Transposase
CRT35_RS26580 () 141144..141767 + 624 WP_000912556.1 potassium channel family protein -
CRT35_RS26585 () 141852..142103 + 252 Protein_160 iron-containing alcohol dehydrogenase -
CRT35_RS26590 () 142392..142709 - 318 Protein_161 IS110 family transposase IS1618 Transposase
CRT35_RS26595 () 142864..142969 + 106 Protein_162 plasmid SOS inhibition protein A -
- () 142938..143136 + 199 NuclAT_0 - -
- () 142938..143136 + 199 NuclAT_0 - -
- () 142938..143136 + 199 NuclAT_0 - -
- () 142938..143136 + 199 NuclAT_0 - -
CRT35_RS26600 () 143201..143359 + 159 WP_001302184.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
CRT35_RS27460 () 143732..144025 + 294 WP_175271036.1 hypothetical protein -
CRT35_RS27465 () 144027..144233 + 207 WP_000275854.1 hypothetical protein -
CRT35_RS26610 () 144258..144545 + 288 WP_000107242.1 hypothetical protein -
CRT35_RS26615 () 144664..145485 + 822 WP_001234465.1 DUF945 domain-containing protein -
CRT35_RS26620 () 145781..146353 - 573 WP_000949660.1 hypothetical protein VF
CRT35_RS26625 () 146723..147106 + 384 WP_001063020.1 relaxosome protein TraM -
CRT35_RS26630 () 147297..147944 + 648 WP_000332520.1 conjugal transfer transcriptional regulator TraJ -
CRT35_RS26635 () 148080..148295 + 216 WP_001352842.1 conjugal transfer relaxosome protein TraY -
CRT35_RS26640 () 148338..148703 + 366 WP_000340282.1 type IV conjugative transfer system pilin TraA -
CRT35_RS26645 () 148718..149029 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
CRT35_RS26650 () 149051..149617 + 567 WP_000399790.1 type IV conjugative transfer system protein TraE -
CRT35_RS26655 () 149628..150332 + 705 WP_148713163.1 type-F conjugative transfer system secretin TraK -
CRT35_RS26660 () 150332..151759 + 1428 WP_001553836.1 conjugal transfer protein TraB -
CRT35_RS26665 () 151749..152339 + 591 WP_000002787.1 conjugal transfer protein TraP -
CRT35_RS26670 () 152326..152463 + 138 WP_001553834.1 conjugal transfer protein TrbD -
CRT35_RS26675 () 152485..152646 + 162 WP_000741714.1 conjugal transfer protein TrbD -
CRT35_RS26680 () 152639..152890 + 252 WP_001038342.1 conjugal transfer protein TrbG -
CRT35_RS26685 () 152887..153402 + 516 WP_000809832.1 type IV conjugative transfer system lipoprotein TraV -
CRT35_RS26690 () 153537..153758 + 222 WP_001278692.1 conjugal transfer protein TraR -
CRT35_RS26695 () 153918..156545 + 2628 WP_001064264.1 type IV secretion system protein TraC -
CRT35_RS26700 () 156542..156928 + 387 WP_000099690.1 type-F conjugative transfer system protein TrbI -
CRT35_RS26705 () 156925..157557 + 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
CRT35_RS26710 () 157554..158546 + 993 WP_001553833.1 conjugal transfer pilus assembly protein TraU -
CRT35_RS26715 () 158555..159193 + 639 WP_001553832.1 type-F conjugative transfer system pilin assembly protein TrbC -
CRT35_RS26720 () 159190..160998 + 1809 WP_001553831.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
CRT35_RS26725 () 161025..161282 + 258 WP_000864318.1 conjugal transfer protein TrbE -
CRT35_RS26730 () 161275..162018 + 744 WP_001030378.1 type-F conjugative transfer system pilin assembly protein TraF -
CRT35_RS26735 () 162034..162372 + 339 WP_001287905.1 conjugal transfer protein TrbA -
CRT35_RS26740 () 162499..162783 + 285 WP_000623730.1 type-F conjugative transfer system pilin chaperone TraQ -
CRT35_RS26745 () 162770..163315 + 546 WP_000059832.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
CRT35_RS26750 () 163245..163586 + 342 WP_071594226.1 P-type conjugative transfer protein TrbJ -
CRT35_RS26755 () 163534..163959 + 426 WP_071594227.1 F-type conjugal transfer protein TrbF -
CRT35_RS26760 () 163946..165319 + 1374 WP_001696604.1 conjugal transfer protein TraH -
CRT35_RS26765 () 165316..168141 + 2826 WP_029702178.1 conjugal transfer mating pair stabilization protein TraG -
CRT35_RS26770 () 168138..168647 + 510 WP_024168260.1 conjugal transfer entry exclusion protein TraS -
CRT35_RS26775 () 168661..169392 + 732 WP_001734698.1 complement resistance protein TraT -
CRT35_RS26780 () 169644..171806 + 2163 WP_033549787.1 type IV conjugative transfer system coupling protein TraD -
CRT35_RS26785 () 171806..177076 + 5271 WP_012372808.1 Multifunctional conjugation protein TraI Relaxase
CRT35_RS26790 () 177096..177842 + 747 WP_000205701.1 conjugal transfer pilus acetylase TraX -
CRT35_RS26795 () 177897..178457 + 561 WP_000139363.1 fertility inhibition protein FinO -
CRT35_RS26800 () 178590..178802 + 213 WP_005012601.1 hypothetical protein -
CRT35_RS26810 () 179103..179805 - 703 Protein_205 IS1 family transposase IS1S Transposase
CRT35_RS26815 () 179906..180088 + 183 WP_000968309.1 hypothetical protein -
- () 180227..180288 - 62 NuclAT_1 - -
- () 180227..180288 - 62 NuclAT_1 - -
- () 180227..180288 - 62 NuclAT_1 - -
- () 180227..180288 - 62 NuclAT_1 - -
CRT35_RS26825 () 180275..180481 + 207 WP_015387399.1 type I toxin-antitoxin system Hok family toxin -
CRT35_RS26830 () 180765..181022 + 258 WP_000083833.1 replication regulatory protein RepA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance