MGE detailed information
MGE type: Conjugative plasmid MGE length: 146496 bp
Accession: NZ_CP010214 Location: 1..146496 Organism: Escherichia coli strain M15 Replicon: plasmid A
Accession: NZ_CP010214 Location: 1..146496 Organism: Escherichia coli strain M15 Replicon: plasmid A
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RG61_RS26555 () | 62..610 | - | 549 | Protein_0 | AAA family ATPase | - |
| RG61_RS26560 () | 610..1755 | - | 1146 | WP_073519881.1 | IS21 family transposase IS21 | Transposase |
| RG61_RS29175 () | 1958..2062 | - | 105 | Protein_2 | aerotaxis sensor receptor, flavoprotein | - |
| RG61_RS26575 () | 2494..2562 | + | 69 | Protein_3 | DUF4113 domain-containing protein | - |
| RG61_RS28505 () | 2684..3440 | - | 757 | Protein_4 | IS4 family transposase ISEc13 | Transposase |
| RG61_RS26590 () | 3674..4636 | - | 963 | WP_000756325.1 | ParB/RepB/Spo0J family partition protein | - |
| RG61_RS26595 () | 4633..5838 | - | 1206 | WP_000817644.1 | Plasmid partition protein A | VF |
| RG61_RS26600 () | 6037..6222 | - | 186 | WP_073519882.1 | hypothetical protein | - |
| RG61_RS26605 () | 6212..6424 | + | 213 | WP_032334873.1 | hypothetical protein | - |
| RG61_RS26610 () | 6393..6599 | - | 207 | WP_073519883.1 | hypothetical protein | - |
| RG61_RS26615 () | 6589..6840 | + | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| RG61_RS26620 () | 6837..7124 | + | 288 | WP_001270417.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| RG61_RS29180 () | 7123..7403 | + | 281 | Protein_12 | IS3 family transposase ISKpn37 | Transposase |
| RG61_RS26640 () | 8053..9030 | + | 978 | WP_000361618.1 | RepB family plasmid replication initiator protein | - |
| RG61_RS26645 () | 9315..10055 | - | 741 | WP_073519885.1 | site-specific integrase | - |
| RG61_RS26650 () | 10218..10364 | - | 147 | WP_073519886.1 | serine/threonine protein kinase | - |
| RG61_RS26655 () | 10726..10973 | + | 248 | Protein_16 | hypothetical protein | - |
| RG61_RS26660 () | 11046..11894 | + | 849 | WP_073519985.1 | hypothetical protein | - |
| RG61_RS26665 () | 12147..12356 | - | 210 | Protein_18 | hypothetical protein | - |
| RG61_RS29185 () | 12358..12464 | - | 107 | Protein_19 | IS110 family transposase | - |
| RG61_RS26670 () | 12800..13069 | - | 270 | Protein_20 | transcriptional regulator | - |
| RG61_RS26675 () | 13205..13402 | - | 198 | WP_049035580.1 | hypothetical protein | - |
| RG61_RS28510 () | 13399..14398 | - | 1000 | Protein_22 | colicin transporter | - |
| RG61_RS29190 () | 14457..14660 | + | 204 | WP_141221903.1 | hypothetical protein | - |
| RG61_RS26695 () | 14674..15099 | - | 426 | Protein_24 | IS3 family transposase ISEc16 | Transposase |
| RG61_RS26705 () | 16021..19950 | + | 3930 | WP_073519890.1 | Serine protease EspC | VF |
| RG61_RS26710 () | 20035..20319 | + | 285 | WP_077897980.1 | Major pilu subunit operon regulatory protein PapB | VF |
| RG61_RS26715 () | 20561..21322 | - | 762 | WP_073519892.1 | hypothetical protein | VF |
| RG61_RS26720 () | 21339..22103 | - | 765 | WP_073519893.1 | hypothetical protein | VF |
| RG61_RS26725 () | 22133..22930 | - | 798 | WP_073519894.1 | hypothetical protein | VF |
| RG61_RS26730 () | 23128..23925 | - | 798 | WP_073519895.1 | hypothetical protein | - |
| RG61_RS26735 () | 24147..24638 | - | 492 | WP_073519896.1 | hypothetical protein | VF |
| RG61_RS26740 () | 24673..25449 | - | 777 | WP_073519897.1 | Chaperone protein FaeE | VF |
| RG61_RS26745 () | 25442..27868 | - | 2427 | WP_077897984.1 | Outer membrane usher protein YraJ | VF |
| RG61_RS26750 () | 27901..28443 | - | 543 | WP_073519899.1 | hypothetical protein | VF |
| RG61_RS26755 () | 28451..28750 | - | 300 | WP_073519900.1 | Major pilu subunit operon regulatory protein PapB | VF |
| RG61_RS29195 () | 29238..29444 | + | 207 | WP_149025693.1 | hypothetical protein | - |
| RG61_RS29200 () | 29536..29776 | + | 241 | Protein_37 | IS91 family transposase | - |
| RG61_RS26765 () | 29899..30408 | + | 510 | Protein_38 | HNH endonuclease | - |
| RG61_RS26770 () | 30472..31253 | - | 782 | Protein_39 | IS21 family transposase IS100kyp | Transposase |
| RG61_RS26775 () | 31250..32271 | - | 1022 | Protein_40 | IS21 family transposase IS100kyp | Transposase |
| RG61_RS26780 () | 32324..32587 | + | 264 | WP_077897983.1 | HNH endonuclease | - |
| RG61_RS28515 () | 32619..33376 | - | 758 | Protein_42 | IS3 family transposase | - |
| RG61_RS28520 () | 33525..33738 | - | 214 | Protein_43 | IS1 family transposase | - |
| RG61_RS26800 () | 34262..35494 | + | 1233 | WP_073519904.1 | phosphoadenosine phosphosulfate reductase | - |
| RG61_RS26805 () | 35479..36117 | + | 639 | WP_073519905.1 | ParB N-terminal domain-containing protein | - |
| RG61_RS29205 () | 36342..37535 | - | 1194 | WP_095374788.1 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| RG61_RS29210 () | 37557..38633 | - | 1077 | Protein_47 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| RG61_RS26815 () | 38875..42978 | - | 4104 | WP_073519907.1 | Serine protease pic autotransporter | VF |
| RG61_RS26820 () | 43735..44148 | + | 414 | WP_077897979.1 | GntR family transcriptional regulator | - |
| RG61_RS26825 () | 44182..44367 | + | 186 | WP_077897978.1 | LacI family transcriptional regulator | - |
| RG61_RS26830 () | 44451..45025 | + | 575 | Protein_51 | IS481 family transposase ISErsp1 | Transposase |
| RG61_RS29215 () | 45101..45247 | + | 147 | Protein_52 | 3'-5' exonuclease | - |
| RG61_RS26840 () | 45459..45857 | - | 399 | WP_073519910.1 | hypothetical protein | - |
| RG61_RS26845 () | 45869..46222 | - | 354 | WP_077897977.1 | hypothetical protein | - |
| RG61_RS26850 () | 46592..47011 | - | 420 | WP_073519911.1 | Exc2 family lipoprotein | - |
| RG61_RS28525 () | 46907..47283 | + | 377 | Protein_56 | hypothetical protein | - |
| RG61_RS26855 () | 47696..47890 | + | 195 | Protein_57 | hypothetical protein | - |
| RG61_RS26860 () | 47928..48200 | - | 273 | WP_046201741.1 | hypothetical protein | - |
| RG61_RS26865 () | 48193..48771 | - | 579 | WP_001400936.1 | Tn3 family transposase ISPsy39 | Transposase |
| RG61_RS26870 () | 48921..51968 | + | 3048 | Protein_60 | Tn3 family transposase ISPsy42 | Transposase |
| RG61_RS28530 () | 52173..52319 | - | 147 | Protein_61 | 3'-5' exonuclease | - |
| RG61_RS26880 () | 52480..54669 | - | 2190 | WP_073519912.1 | peptidase domain-containing ABC transporter | - |
| RG61_RS26885 () | 54669..55922 | - | 1254 | WP_073519913.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| RG61_RS26890 () | 56025..56660 | - | 636 | WP_073519914.1 | CPBP family intramembrane metalloprotease | - |
| RG61_RS26895 () | 56665..56865 | - | 201 | WP_073519915.1 | hypothetical protein | - |
| RG61_RS29220 () | 56890..57252 | - | 363 | WP_071597330.1 | hypothetical protein | - |
| RG61_RS29225 () | 57486..57569 | - | 84 | Protein_67 | maturase | - |
| RG61_RS26905 () | 57727..58266 | + | 540 | WP_077897976.1 | Tn3 family transposase TnpR_ISRsp12 | Transposase |
| RG61_RS26910 () | 58259..58531 | + | 273 | WP_046201741.1 | hypothetical protein | - |
| RG61_RS26915 () | 58535..58834 | - | 300 | WP_073519916.1 | hypothetical protein | - |
| RG61_RS26920 () | 58986..59201 | - | 216 | WP_073519917.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| RG61_RS26925 () | 59198..59467 | - | 270 | WP_073519918.1 | hypothetical protein | Antitoxin Detail |
| RG61_RS26935 () | 59679..59810 | + | 132 | WP_071595370.1 | replication protein RepA4 | - |
| RG61_RS26940 () | 59826..60020 | - | 195 | WP_073519921.1 | replication protein | - |
| RG61_RS26945 () | 60382..61210 | - | 829 | Protein_75 | incFII family plasmid replication initiator RepA | - |
| RG61_RS26950 () | 61203..61277 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| RG61_RS26955 () | 61344..61492 | + | 149 | Protein_77 | replication protein RepA | - |
| RG61_RS26960 () | 61509..61766 | - | 258 | WP_073519922.1 | replication regulatory protein RepA | - |
| RG61_RS26965 () | 61967..62116 | - | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 62165..62221 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 62165..62221 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 62165..62221 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 62165..62221 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| RG61_RS26970 () | 62172..62414 | + | 243 | WP_071996372.1 | hypothetical protein | - |
| RG61_RS26975 () | 62394..62984 | - | 591 | WP_032334802.1 | DUF2726 domain-containing protein | - |
| RG61_RS26980 () | 63022..63231 | - | 210 | WP_001299729.1 | hemolysin expression modulator Hha | - |
| RG61_RS26985 () | 63277..63738 | - | 462 | WP_077898159.1 | thermonuclease family protein | - |
| RG61_RS26990 () | 63981..64193 | - | 213 | WP_032334799.1 | hypothetical protein | - |
| RG61_RS26995 () | 64327..64887 | - | 561 | Protein_85 | fertility inhibition protein FinO | - |
| RG61_RS27000 () | 64942..65676 | - | 735 | WP_073519924.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| RG61_RS27005 () | 65720..67873 | - | 2154 | WP_073519925.1 | peptidase domain-containing ABC transporter | - |
| RG61_RS27010 () | 67875..69095 | - | 1221 | WP_073519926.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| RG61_RS27015 () | 69129..69701 | - | 573 | WP_073519927.1 | hypothetical protein | - |
| RG61_RS27020 () | 70004..70114 | - | 111 | WP_073519988.1 | conjugal transfer protein TraI | - |
| RG61_RS27025 () | 70105..70293 | + | 189 | Protein_91 | transposase | - |
| RG61_RS27030 () | 70292..70513 | + | 222 | Protein_92 | IS1 family transposase IS1N | Transposase |
| RG61_RS29230 () | 70591..70864 | - | 274 | Protein_93 | hypothetical protein | - |
| RG61_RS27035 () | 71034..72143 | - | 1110 | WP_073519929.1 | N-acetylneuraminate epimerase | - |
| RG61_RS27040 () | 72153..72863 | - | 711 | WP_073519930.1 | N-acetylneuraminic acid channel protein | - |
| RG61_RS27045 () | 72917..73726 | - | 810 | WP_073519931.1 | alpha/beta hydrolase | - |
| RG61_RS27050 () | 73742..75208 | - | 1467 | WP_073519932.1 | MFS transporter | - |
| RG61_RS27055 () | 75279..76154 | - | 876 | WP_073519989.1 | N-acetylmannosamine kinase | - |
| RG61_RS27060 () | 76214..77113 | - | 900 | WP_073519990.1 | N-acetylneuraminate lyase | - |
| RG61_RS27065 () | 77250..78335 | - | 1086 | WP_077897982.1 | hypothetical protein | - |
| RG61_RS27070 () | 78405..79133 | + | 729 | WP_034173832.1 | transcriptional regulator NanR | - |
| RG61_RS27075 () | 79158..80042 | - | 885 | WP_034173833.1 | alpha/beta hydrolase | - |
| RG61_RS29235 () | 80182..80298 | + | 117 | Protein_103 | IS21 family transposase | - |
| RG61_RS27085 () | 80562..80768 | - | 207 | WP_073519933.1 | hypothetical protein | - |
| RG61_RS27090 () | 80904..81464 | - | 561 | Protein_105 | fertility inhibition protein FinO | - |
| RG61_RS27095 () | 81519..82253 | - | 735 | WP_073519934.1 | conjugal transfer pilus acetylase TraX | - |
| RG61_RS27100 () | 82270..87540 | - | 5271 | WP_073519935.1 | Multifunctional conjugation protein TraI | Relaxase |
| RG61_RS27105 () | 87540..89693 | - | 2154 | WP_073519936.1 | type IV conjugative transfer system coupling protein TraD | - |
| RG61_RS27110 () | 90290..91021 | - | 732 | WP_123006582.1 | complement resistance protein TraT | - |
| RG61_RS27115 () | 91053..91550 | - | 498 | WP_073519937.1 | surface exclusion protein | - |
| RG61_RS27120 () | 91571..94423 | - | 2853 | WP_073519938.1 | conjugal transfer mating pair stabilization protein TraG | - |
| RG61_RS27125 () | 94420..95838 | - | 1419 | WP_073519939.1 | conjugal transfer protein TraH | - |
| RG61_RS27135 () | 96243..96734 | - | 492 | WP_073519941.1 | hypothetical protein | - |
| RG61_RS27140 () | 96747..97301 | - | 555 | WP_073519942.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| RG61_RS27145 () | 97282..97569 | - | 288 | WP_073519943.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| RG61_RS27150 () | 97659..97994 | + | 336 | WP_073519944.1 | hypothetical protein | - |
| RG61_RS27155 () | 97955..98320 | - | 366 | WP_073519945.1 | hypothetical protein | - |
| RG61_RS27160 () | 98334..99077 | - | 744 | WP_073519946.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| RG61_RS27165 () | 99088..99555 | - | 468 | WP_073519947.1 | hypothetical protein | - |
| RG61_RS27170 () | 99567..101438 | - | 1872 | WP_097455820.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| RG61_RS27175 () | 101686..102066 | - | 381 | WP_073519948.1 | hypothetical protein | - |
| RG61_RS27180 () | 102063..102701 | - | 639 | WP_073519949.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| RG61_RS27185 () | 102710..103702 | - | 993 | WP_073519950.1 | conjugal transfer pilus assembly protein TraU | - |
| RG61_RS27190 () | 103699..104331 | - | 633 | WP_073519951.1 | type-F conjugative transfer system protein TraW | - |
| RG61_RS27195 () | 104328..104714 | - | 387 | WP_073519952.1 | type-F conjugative transfer system protein TrbI | - |
| RG61_RS27200 () | 104711..107338 | - | 2628 | WP_073519953.1 | type IV secretion system protein TraC | - |
| RG61_RS27205 () | 107356..107751 | - | 396 | WP_073519954.1 | hypothetical protein | - |
| RG61_RS27210 () | 107748..108218 | - | 471 | WP_073519955.1 | hypothetical protein | - |
| RG61_RS27215 () | 108215..108691 | - | 477 | WP_073519956.1 | hypothetical protein | - |
| RG61_RS27220 () | 108684..108905 | - | 222 | WP_073519957.1 | conjugal transfer protein TraR | - |
| RG61_RS27225 () | 109040..109555 | - | 516 | WP_073519958.1 | type IV conjugative transfer system lipoprotein TraV | - |
| RG61_RS27230 () | 109552..109905 | - | 354 | WP_077897972.1 | conjugal transfer protein TrbD | - |
| RG61_RS27235 () | 109859..110443 | - | 585 | WP_073519959.1 | conjugal transfer protein TraP | - |
| RG61_RS27240 () | 110412..111860 | - | 1449 | WP_073519960.1 | conjugal transfer protein TraB | - |
| RG61_RS27245 () | 111860..112567 | - | 708 | WP_149025695.1 | type-F conjugative transfer system secretin TraK | - |
| RG61_RS27250 () | 112578..113144 | - | 567 | WP_073519962.1 | type IV conjugative transfer system protein TraE | - |
| RG61_RS27255 () | 113166..113477 | - | 312 | WP_073519963.1 | type IV conjugative transfer system protein TraL | - |
| RG61_RS27260 () | 113492..113851 | - | 360 | WP_073519964.1 | type IV conjugative transfer system pilin TraA | - |
| RG61_RS27265 () | 113885..114112 | - | 228 | WP_073519965.1 | conjugal transfer relaxosome protein TraY | - |
| RG61_RS27270 () | 114469..114891 | - | 423 | WP_073519966.1 | PAS domain-containing protein | - |
| RG61_RS27275 () | 115080..115466 | - | 387 | WP_073519967.1 | relaxosome protein TraM | - |
| RG61_RS27280 () | 115890..116399 | + | 510 | WP_073519994.1 | hypothetical protein | VF |
| RG61_RS27285 () | 116695..117516 | - | 822 | WP_073519968.1 | DUF945 domain-containing protein | - |
| RG61_RS27290 () | 117660..118004 | - | 345 | WP_073519969.1 | hypothetical protein | - |
| RG61_RS27295 () | 117994..118123 | - | 130 | Protein_145 | single-stranded DNA-binding protein | - |
| RG61_RS29240 () | 118055..118264 | + | 210 | Protein_146 | hypothetical protein | - |
| RG61_RS29245 () | 118301..118712 | + | 412 | Protein_147 | hypothetical protein | - |
| RG61_RS29250 () | 118660..118884 | - | 225 | WP_141221904.1 | hypothetical protein | - |
| RG61_RS28545 () | 118897..119337 | - | 441 | WP_149025694.1 | hypothetical protein | - |
| RG61_RS27305 () | 119445..119606 | - | 162 | WP_073519970.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 119659..119836 | - | 178 | NuclAT_0 | - | Antitoxin Detail |
| - () | 119659..119836 | - | 178 | NuclAT_0 | - | Antitoxin Detail |
| - () | 119659..119836 | - | 178 | NuclAT_0 | - | Antitoxin Detail |
| - () | 119659..119836 | - | 178 | NuclAT_0 | - | Antitoxin Detail |
| RG61_RS27310 () | 119684..119835 | + | 152 | Protein_151 | protein sok | - |
| RG61_RS27315 () | 119816..120130 | - | 315 | WP_073519971.1 | theronine dehydrogenase | - |
| RG61_RS27320 () | 120127..120856 | - | 730 | Protein_153 | plasmid SOS inhibition protein A | - |
| RG61_RS27325 () | 120853..121287 | - | 435 | WP_097455818.1 | conjugation system SOS inhibitor PsiB | - |
| RG61_RS27330 () | 121328..123325 | - | 1998 | WP_073519973.1 | ParB/RepB/Spo0J family partition protein | - |
| RG61_RS27335 () | 123395..123637 | - | 243 | WP_073519974.1 | DUF905 domain-containing protein | - |
| RG61_RS27340 () | 123689..124246 | - | 558 | WP_073519975.1 | single-stranded DNA-binding protein | - |
| RG61_RS29255 () | 124278..124367 | - | 90 | WP_072223070.1 | single-stranded DNA-binding protein | - |
| RG61_RS29260 () | 124580..124801 | + | 222 | WP_123006580.1 | hypothetical protein | - |
| RG61_RS27345 () | 124929..125189 | - | 261 | WP_073519976.1 | DNA polymerase III subunit theta | - |
| RG61_RS27350 () | 125629..126105 | - | 477 | Protein_161 | antirestriction protein ArdA | - |
| RG61_RS28550 () | 126684..127656 | + | 973 | Protein_162 | IS110 family transposase ISOt5 | Transposase |
| RG61_RS27365 () | 127759..128454 | - | 696 | WP_073519978.1 | alpha/beta hydrolase | - |
| RG61_RS27370 () | 128497..128805 | - | 309 | WP_073519979.1 | AzlD domain-containing protein | - |
| RG61_RS27375 () | 128802..129509 | - | 708 | WP_073519980.1 | AzlC family ABC transporter permease | - |
| RG61_RS27380 () | 129634..130506 | + | 873 | WP_073519981.1 | HTH-type transcriptional regulator MetR | VF |
| RG61_RS27385 () | 130631..131557 | - | 927 | WP_073519982.1 | hypothetical protein | - |
| RG61_RS29265 () | 131796..131879 | - | 84 | Protein_168 | hypothetical protein | - |
| RG61_RS27390 () | 131872..132768 | - | 897 | WP_106423823.1 | DUF1281 domain-containing protein | - |
| RG61_RS27395 () | 132782..133051 | - | 270 | WP_032072581.1 | hypothetical protein | - |
| RG61_RS27400 () | 133162..133410 | + | 249 | WP_073519983.1 | DinI-like family protein | - |
| RG61_RS27405 () | 133407..133844 | + | 438 | WP_073519984.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| RG61_RS27410 () | 133844..134170 | + | 327 | Protein_173 | hypothetical protein | - |
| RG61_RS27415 () | 134198..134617 | - | 420 | Protein_174 | IS110 family transposase | - |
| RG61_RS27420 () | 135396..144461 | - | 9066 | Protein_175 | tRNA nuclease CdiA | VF |
| RG61_RS27425 () | 144474..146246 | - | 1773 | WP_073519780.1 | ShlB/FhaC/HecB family hemolysin secretion/activation protein | - |
| RG61_RS27430 () | 146289..146477 | + | 189 | WP_001332845.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|