MGE detailed information
MGE type: Conjugative plasmid MGE length: 131843 bp
Accession: NZ_AP023307 Location: 1..131843 Organism: Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4567 Replicon: plasmid L-4567 strain 4[5]12:i:-
Accession: NZ_AP023307 Location: 1..131843 Organism: Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4567 Replicon: plasmid L-4567 strain 4[5]12:i:-
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K5646_RS23880 (101) | 101..1078 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| K5646_RS23885 (1363) | 1363..2103 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| K5646_RS23890 (2224) | 2224..2419 | - | 196 | Protein_2 | serine/threonine protein kinase | - |
| K5646_RS23895 (2506) | 2506..2916 | - | 411 | Protein_3 | IS3 family transposase ISEhe3 | Transposase |
| K5646_RS23900 (2979) | 2979..3683 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K5646_RS23905 (3737) | 3737..4204 | + | 468 | Protein_5 | conjugal transfer protein | - |
| K5646_RS23910 (4449) | 4449..4565 | + | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| K5646_RS23915 (4581) | 4581..6500 | + | 1920 | WP_025989258.1 | Tetracycline resistance protein TetM from transposon TnFO1 | VF |
| K5646_RS23920 (6619) | 6619..6786 | + | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| K5646_RS23925 (6794) | 6794..7024 | - | 231 | WP_136655701.1 | hypothetical protein | - |
| K5646_RS23930 (7047) | 7047..7679 | + | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K5646_RS23935 (7926) | 7926..8258 | - | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K5646_RS23940 (8381) | 8381..9219 | - | 839 | Protein_12 | Streptomycin 3''-adenylyltransferase | ARG |
| K5646_RS23945 (9312) | 9312..10571 | - | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| K5646_RS23950 (10786) | 10786..11624 | - | 839 | Protein_14 | Streptomycin 3''-adenylyltransferase | ARG |
| K5646_RS23955 (11630) | 11630..11920 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| K5646_RS23960 (12032) | 12032..12529 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| K5646_RS23965 (12673) | 12673..13686 | + | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| K5646_RS23970 (13889) | 13889..14239 | + | 351 | WP_071830595.1 | DUF3330 domain-containing protein | - |
| K5646_RS23975 (14365) | 14365..14925 | + | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| K5646_RS23980 (14928) | 14928..17879 | + | 2952 | WP_015344976.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| K5646_RS23985 (17813) | 17813..18289 | + | 477 | WP_223171565.1 | hypothetical protein | - |
| K5646_RS23990 (18374) | 18374..19078 | - | 705 | WP_001067784.1 | IS6 family transposase IS1006 | Transposase |
| K5646_RS23995 (19142) | 19142..19972 | + | 831 | Protein_23 | IS91 family transposase ISVsa3 | Transposase |
| K5646_RS24880 (20003) | 20003..20887 | + | 885 | WP_012728215.1 | DUF3363 domain-containing protein | - |
| K5646_RS24005 (21104) | 21104..22318 | + | 1215 | WP_058657119.1 | Bicyclomycin resistance protein | ARG |
| K5646_RS24010 (22346) | 22346..22651 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| K5646_RS24015 (22763) | 22763..24256 | + | 1494 | WP_015344975.1 | IS91 family transposase ISVsa3 | Transposase |
| K5646_RS24020 (24492) | 24492..24734 | - | 243 | Protein_28 | phosphoglucosamine mutase | - |
| K5646_RS24025 (24821) | 24821..25636 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| K5646_RS24030 (25726) | 25726..26816 | + | 1091 | WP_085940648.1 | IS4-like element ISAba1 family transposase | - |
| K5646_RS24885 (27013) | 27013..27300 | - | 288 | WP_230071785.1 | hypothetical protein | - |
| K5646_RS24040 (27548) | 27548..28252 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K5646_RS24045 (28318) | 28318..29832 | + | 1515 | Protein_33 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K5646_RS24050 (29890) | 29890..30132 | + | 243 | WP_000844627.1 | transposase | - |
| K5646_RS24055 (30164) | 30164..30814 | - | 651 | WP_001493764.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| K5646_RS24060 (30920) | 30920..32119 | + | 1200 | WP_001493765.1 | Tetracycline resistance protein, class C | ARG |
| K5646_RS24065 (32151) | 32151..33035 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| K5646_RS24070 (33173) | 33173..33607 | - | 435 | WP_223963367.1 | isochorismatase family cysteine hydrolase | - |
| K5646_RS24075 (33570) | 33570..35231 | + | 1662 | Protein_39 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K5646_RS24080 (35333) | 35333..35590 | + | 258 | WP_231363335.1 | hypothetical protein | - |
| K5646_RS24085 (35699) | 35699..36403 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K5646_RS24090 (36455) | 36455..36706 | + | 252 | Protein_42 | hypothetical protein | - |
| K5646_RS24095 (36852) | 36852..37715 | + | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| K5646_RS24100 (37753) | 37753..37998 | + | 246 | WP_001354008.1 | GrpB family protein | - |
| K5646_RS24105 (38467) | 38467..39258 | + | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| K5646_RS24110 (39516) | 39516..40376 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| K5646_RS24115 (40559) | 40559..41116 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K5646_RS24120 (41375) | 41375..42079 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| K5646_RS24125 (42128) | 42128..42463 | - | 336 | Protein_49 | IS4 family transposase IS10R | Transposase |
| K5646_RS24130 (42606) | 42606..43466 | + | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| K5646_RS24135 (43479) | 43479..44021 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| K5646_RS24140 (44164) | 44164..44538 | - | 375 | Protein_52 | IS6 family transposase IS26 | Transposase |
| K5646_RS24145 (44573) | 44573..45427 | - | 855 | Protein_53 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| K5646_RS24150 (45601) | 45601..47226 | + | 1626 | WP_039026394.1 | Phosphoethanolamine transferase EptA | VF |
| K5646_RS24155 (47344) | 47344..47724 | + | 381 | WP_039026395.1 | diacylglycerol kinase | - |
| K5646_RS24160 (47919) | 47919..48233 | + | 315 | WP_039026396.1 | IS3 family transposase ISKpn40 | Transposase |
| K5646_RS24165 (48269) | 48269..49051 | + | 783 | WP_223936907.1 | IS3 family transposase ISKpn40 | Transposase |
| K5646_RS24170 (49035) | 49035..49256 | + | 222 | WP_226909166.1 | hypothetical protein | - |
| K5646_RS24175 (49576) | 49576..49962 | - | 387 | WP_063102497.1 | bleomycin binding protein | - |
| K5646_RS24180 (50156) | 50156..50860 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| K5646_RS24890 (50921) | 50921..51001 | + | 81 | Protein_61 | MerR family transcriptional regulator | - |
| K5646_RS24185 (51035) | 51035..52081 | + | 1047 | Protein_62 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K5646_RS24190 (52115) | 52115..52615 | + | 501 | Protein_63 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K5646_RS24195 (52649) | 52649..52837 | + | 189 | Protein_64 | IS3 family transposase | - |
| K5646_RS24200 (52912) | 52912..53199 | - | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| K5646_RS24205 (53196) | 53196..53447 | - | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| K5646_RS24210 (54413) | 54413..55270 | - | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| K5646_RS24215 (55263) | 55263..55337 | - | 75 | WP_061357229.1 | RepA leader peptide Tap | - |
| K5646_RS24220 (55569) | 55569..55826 | - | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| K5646_RS24225 (56094) | 56094..56243 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (56287) | 56287..56348 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (56287) | 56287..56348 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (56287) | 56287..56348 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (56287) | 56287..56348 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| K5646_RS24230 (56690) | 56690..56902 | - | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| K5646_RS24235 (57037) | 57037..57597 | - | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| K5646_RS24240 (57652) | 57652..58395 | - | 744 | WP_039002216.1 | conjugal transfer pilus acetylase TraX | - |
| K5646_RS24245 (58415) | 58415..63685 | - | 5271 | WP_054377139.1 | Multifunctional conjugation protein TraI | Relaxase |
| K5646_RS24250 (63685) | 63685..65865 | - | 2181 | WP_063078088.1 | type IV conjugative transfer system coupling protein TraD | - |
| K5646_RS24255 (66118) | 66118..66849 | - | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| K5646_RS24260 (66881) | 66881..67384 | - | 504 | WP_000605510.1 | hypothetical protein | - |
| K5646_RS24265 (67399) | 67399..70221 | - | 2823 | WP_001007048.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| K5646_RS24270 (70218) | 70218..71594 | - | 1377 | WP_000982842.1 | conjugal transfer pilus assembly protein TraH | - |
| K5646_RS24275 (71591) | 71591..71953 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| K5646_RS24280 (71883) | 71883..72428 | - | 546 | WP_000052613.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| K5646_RS24285 (72415) | 72415..72696 | - | 282 | WP_039002206.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| K5646_RS24290 (72812) | 72812..73555 | - | 744 | WP_039002205.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| K5646_RS24295 (73548) | 73548..73808 | - | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| K5646_RS24300 (73835) | 73835..75643 | - | 1809 | WP_000821844.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| K5646_RS24305 (75640) | 75640..76278 | - | 639 | WP_000777691.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| K5646_RS24310 (76287) | 76287..77279 | - | 993 | WP_023148235.1 | conjugal transfer pilus assembly protein TraU | - |
| K5646_RS24315 (77276) | 77276..77908 | - | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| K5646_RS24320 (77905) | 77905..78291 | - | 387 | WP_039002198.1 | type-F conjugative transfer system protein TrbI | - |
| K5646_RS24325 (78288) | 78288..80915 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| K5646_RS24330 (81075) | 81075..81296 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| K5646_RS24335 (81431) | 81431..81946 | - | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| K5646_RS24340 (81943) | 81943..82263 | - | 321 | WP_063078087.1 | conjugal transfer protein TrbD | - |
| K5646_RS24345 (82250) | 82250..82837 | - | 588 | WP_000002772.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| K5646_RS24350 (82827) | 82827..84254 | - | 1428 | WP_000146690.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| K5646_RS24355 (84254) | 84254..84982 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| K5646_RS24360 (84969) | 84969..85535 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| K5646_RS24365 (85557) | 85557..85868 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| K5646_RS24370 (85873) | 85873..86235 | - | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| K5646_RS24375 (86268) | 86268..86669 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| K5646_RS24380 (86762) | 86762..87451 | - | 690 | WP_039002187.1 | conjugal transfer transcriptional regulator TraJ | - |
| K5646_RS24385 (87638) | 87638..88021 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| K5646_RS24390 (88342) | 88342..88944 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| K5646_RS24395 (89241) | 89241..90062 | - | 822 | WP_072795862.1 | DUF932 domain-containing protein | - |
| K5646_RS24400 (90185) | 90185..90472 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| K5646_RS24895 (90497) | 90497..90703 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| K5646_RS24900 (90773) | 90773..90946 | + | 174 | Protein_107 | hypothetical protein | - |
| K5646_RS24905 (90944) | 90944..91174 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| K5646_RS24405 (91394) | 91394..91519 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| K5646_RS24910 (91461) | 91461..91610 | - | 150 | Protein_110 | plasmid maintenance protein Mok | - |
| - (91596) | 91596..91820 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (91596) | 91596..91820 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (91596) | 91596..91820 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (91596) | 91596..91820 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| K5646_RS24410 (91832) | 91832..92551 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| K5646_RS24415 (92548) | 92548..92982 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| K5646_RS24420 (93037) | 93037..94995 | - | 1959 | WP_039000998.1 | ParB/RepB/Spo0J family partition protein | - |
| K5646_RS24425 (95060) | 95060..95293 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| K5646_RS24430 (95350) | 95350..95889 | - | 540 | WP_032332913.1 | single-stranded DNA-binding protein | - |
| K5646_RS24435 (95915) | 95915..96121 | - | 207 | WP_000275853.1 | hypothetical protein | - |
| K5646_RS24915 (96362) | 96362..96589 | - | 228 | WP_071961421.1 | hypothetical protein | - |
| K5646_RS24440 (96741) | 96741..97304 | - | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| K5646_RS24445 (97352) | 97352..98713 | - | 1362 | WP_038999961.1 | DUF3560 domain-containing protein | - |
| K5646_RS24450 (98765) | 98765..98995 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| K5646_RS24455 (100030) | 100030..100221 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| K5646_RS24460 (100218) | 100218..100640 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| K5646_RS24465 (100687) | 100687..101112 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| K5646_RS24470 (101529) | 101529..102305 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| K5646_RS24475 (102356) | 102356..102874 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| K5646_RS24480 (102804) | 102804..103025 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| K5646_RS24485 (103026) | 103026..103709 | - | 684 | WP_000086185.1 | DNA methylase | - |
| K5646_RS24490 (103786) | 103786..104097 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| K5646_RS24495 (104094) | 104094..104996 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| K5646_RS24500 (105414) | 105414..105662 | + | 249 | WP_000618110.1 | DinI-like family protein | - |
| K5646_RS24505 (105659) | 105659..106096 | + | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K5646_RS24510 (106096) | 106096..107367 | + | 1272 | WP_000457518.1 | Y-family DNA polymerase | - |
| K5646_RS24515 (107372) | 107372..107764 | - | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| K5646_RS24520 (107769) | 107769..108740 | - | 972 | WP_001103690.1 | plasmid segregation protein ParM | - |
| K5646_RS24525 (108962) | 108962..109606 | + | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| K5646_RS24530 (109600) | 109600..109875 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| K5646_RS24535 (110027) | 110027..110803 | - | 777 | Protein_137 | site-specific integrase | - |
| K5646_RS24540 (110800) | 110800..111306 | - | 507 | WP_001505085.1 | hypothetical protein | - |
| K5646_RS24545 (111297) | 111297..112001 | + | 705 | WP_065304467.1 | IS6 family transposase IS26 | Transposase |
| K5646_RS24550 (112150) | 112150..113475 | - | 1326 | WP_021512928.1 | reactive chlorine resistance oxidoreductase RclA | - |
| K5646_RS24555 (113585) | 113585..114282 | + | 698 | WP_114161604.1 | IS1 family transposase IS1R | Transposase |
| K5646_RS24560 (114383) | 114383..114664 | - | 282 | WP_000639434.1 | hypothetical protein | - |
| K5646_RS24565 (114766) | 114766..115659 | - | 894 | Protein_143 | IS3 family transposase ISEhe3 | Transposase |
| K5646_RS24570 (115727) | 115727..116545 | + | 819 | Protein_144 | IS30 family transposase IS30D | Transposase |
| K5646_RS24580 (117880) | 117880..118029 | + | 150 | Protein_146 | IS30 family transposase IS30D | Transposase |
| K5646_RS24585 (118454) | 118454..118738 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| K5646_RS24590 (118758) | 118758..119891 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| K5646_RS24920 (120154) | 120154..121791 | - | 1638 | WP_223201785.1 | hypothetical protein | - |
| K5646_RS24925 (121842) | 121842..122672 | - | 831 | WP_223201786.1 | hypothetical protein | - |
| K5646_RS24930 (122724) | 122724..123272 | - | 549 | WP_039002808.1 | hypothetical protein | - |
| K5646_RS24600 (123578) | 123578..123808 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K5646_RS24605 (123805) | 123805..124221 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K5646_RS24610 (124383) | 124383..126521 | - | 2139 | WP_039002805.1 | AAA family ATPase | - |
| K5646_RS24615 (126986) | 126986..127981 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| K5646_RS24620 (128024) | 128024..128917 | + | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| K5646_RS24935 (129899) | 129899..130057 | + | 159 | WP_228955855.1 | abortive infection family protein | - |
| K5646_RS24635 (130216) | 130216..131188 | - | 973 | Protein_159 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|