MGE detailed information
MGE type: Conjugative plasmid MGE length: 139020 bp
Accession: NZ_AP022223 Location: 1..139020 Organism: Escherichia coli strain WP8-S17-ESBL-12 Replicon: plasmid pWP8-S17-ESBL-12_1
Accession: NZ_AP022223 Location: 1..139020 Organism: Escherichia coli strain WP8-S17-ESBL-12 Replicon: plasmid pWP8-S17-ESBL-12_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7R20_RS23685 () | 30..466 | - | 437 | Protein_0 | transposase | - |
| H7R20_RS23690 () | 748..2718 | + | 1971 | WP_001496335.1 | TonB-dependent hemoglobin/transferrin/lactoferrin family receptor | - |
| H7R20_RS23695 () | 2725..3516 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| H7R20_RS23700 () | 3579..4187 | - | 609 | Protein_3 | IS66 family transposase | - |
| H7R20_RS23705 () | 4255..5034 | - | 780 | WP_001297096.1 | IS21-like element IS100kyp family helper ATPase IstB | - |
| H7R20_RS23710 () | 5034..6056 | - | 1023 | WP_000255956.1 | IS21-like element IS100 family transposase | - |
| H7R20_RS23715 () | 6142..7087 | - | 946 | Protein_6 | IS66 family transposase | - |
| H7R20_RS23720 () | 7136..7510 | - | 375 | WP_024193849.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| H7R20_RS23725 () | 7535..8239 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| H7R20_RS23730 () | 8292..8771 | + | 480 | Protein_9 | recombinase family protein | - |
| H7R20_RS23735 () | 8956..9513 | + | 558 | WP_000108589.1 | OsmC family protein | - |
| H7R20_RS23740 () | 9655..10236 | + | 582 | WP_000210409.1 | TetR/AcrR family transcriptional regulator | - |
| H7R20_RS23745 () | 10241..10579 | + | 339 | WP_000888080.1 | carboxymuconolactone decarboxylase family protein | - |
| H7R20_RS23750 () | 10609..10938 | - | 330 | WP_002431133.1 | thioredoxin family protein | - |
| H7R20_RS23755 () | 11152..12258 | + | 1107 | WP_000039982.1 | alkene reductase | - |
| H7R20_RS23760 () | 12324..13025 | + | 702 | WP_001194013.1 | DsbA family oxidoreductase | - |
| H7R20_RS23765 () | 13091..13864 | + | 774 | WP_032152933.1 | SDR family oxidoreductase | - |
| H7R20_RS23770 () | 14050..15273 | - | 1224 | WP_000872613.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| H7R20_RS23775 () | 15404..16276 | - | 873 | WP_000090196.1 | DMT family transporter | - |
| H7R20_RS23780 () | 16518..17270 | + | 753 | WP_000734115.1 | alpha/beta hydrolase | - |
| H7R20_RS23785 () | 17297..17610 | + | 314 | Protein_20 | Tn3 family transposase | - |
| H7R20_RS23790 () | 17710..18714 | + | 1005 | WP_000427620.1 | IS110-like element IS4321 family transposase | - |
| H7R20_RS23795 () | 18991..19095 | + | 105 | Protein_22 | IS5/IS1182 family transposase | - |
| H7R20_RS23800 () | 19245..19877 | - | 633 | Protein_23 | histidine-type phosphatase | - |
| H7R20_RS23805 () | 19999..20484 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| H7R20_RS23810 () | 20509..20994 | - | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| H7R20_RS23815 () | 20981..21676 | - | 696 | WP_000117262.1 | ABC transporter ATP-binding protein | - |
| H7R20_RS23820 () | 21681..22811 | - | 1131 | WP_000729219.1 | ABC transporter permease | - |
| H7R20_RS23825 () | 22801..24084 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| H7R20_RS23830 () | 24087..25466 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| H7R20_RS23835 () | 25570..26097 | - | 528 | WP_000178050.1 | iron transporter | - |
| H7R20_RS23840 () | 26138..28024 | - | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| H7R20_RS23845 () | 28371..29186 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| H7R20_RS23850 () | 29369..29875 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| H7R20_RS23855 () | 29865..30023 | - | 159 | WP_000449408.1 | DsbA family protein | - |
| H7R20_RS23860 () | 30486..31183 | + | 698 | Protein_35 | IS1 family transposase | - |
| H7R20_RS23865 () | 31198..32361 | + | 1164 | Protein_36 | IS4-like element ISVsa5 family transposase | - |
| H7R20_RS23870 () | 32371..32742 | - | 372 | WP_035689358.1 | helix-turn-helix domain-containing protein | - |
| H7R20_RS23875 () | 32875..33468 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| H7R20_RS23880 () | 33581..34786 | - | 1206 | WP_001089068.1 | tetracycline efflux MFS transporter Tet(B) | - |
| H7R20_RS23885 () | 34868..35491 | + | 624 | WP_000088605.1 | tetracycline resistance transcriptional repressor TetR(B) | - |
| H7R20_RS23890 () | 35469..36155 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| H7R20_RS23895 () | 36163..36549 | - | 387 | WP_000460651.1 | hypothetical protein | - |
| H7R20_RS23900 () | 36542..36723 | - | 182 | Protein_43 | antibiotic biosynthesis monooxygenase | - |
| H7R20_RS23905 () | 36699..37396 | - | 698 | Protein_44 | IS1 family transposase | - |
| H7R20_RS23910 () | 37488..38147 | + | 660 | WP_000412211.1 | type A-1 chloramphenicol O-acetyltransferase | - |
| H7R20_RS23915 () | 38348..38725 | - | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| H7R20_RS23920 () | 39036..40040 | - | 1005 | WP_000427620.1 | IS110-like element IS4321 family transposase | - |
| H7R20_RS23925 () | 40119..43085 | - | 2967 | WP_001138064.1 | Tn3-like element TnAs3 family transposase | - |
| H7R20_RS23930 () | 43088..43648 | - | 561 | WP_021532377.1 | recombinase family protein | - |
| H7R20_RS23935 () | 43699..44403 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| H7R20_RS23940 () | 44602..44880 | - | 279 | WP_004217866.1 | DUF3330 domain-containing protein | - |
| H7R20_RS23945 () | 44944..45648 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| H7R20_RS23950 () | 45702..46769 | - | 1068 | Protein_53 | AAA family ATPase | - |
| H7R20_RS23955 () | 46844..47260 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| H7R20_RS23960 () | 47257..47487 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| H7R20_RS23965 () | 48047..48265 | + | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| H7R20_RS23970 () | 48267..48572 | + | 306 | WP_182924578.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| H7R20_RS23975 () | 48573..49379 | + | 807 | WP_000016970.1 | site-specific integrase | - |
| H7R20_RS23980 () | 50101..50856 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| H7R20_RS23985 () | 51444..52610 | + | 1167 | WP_000772446.1 | plasmid-partitioning protein SopA | - |
| H7R20_RS23990 () | 52610..53581 | + | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| H7R20_RS23995 () | 54319..55221 | + | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| H7R20_RS24000 () | 55225..55529 | + | 305 | Protein_63 | hypothetical protein | - |
| H7R20_RS24005 () | 55606..56289 | + | 684 | WP_040110341.1 | DNA methylase | - |
| H7R20_RS24010 () | 56290..56511 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| H7R20_RS24015 () | 56525..56959 | + | 435 | WP_001546462.1 | DUF1380 family protein | - |
| H7R20_RS24020 () | 57004..57774 | + | 771 | WP_001006251.1 | hypothetical protein | - |
| H7R20_RS24025 () | 58311..58613 | + | 303 | WP_001666994.1 | antirestriction protein | - |
| H7R20_RS24030 () | 58660..59082 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
| H7R20_RS24035 () | 59079..59270 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| H7R20_RS24040 () | 59542..59790 | - | 249 | WP_071781657.1 | hypothetical protein | - |
| H7R20_RS24045 () | 60302..60532 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| H7R20_RS24050 () | 60584..61945 | + | 1362 | WP_000199439.1 | DUF3560 domain-containing protein | - |
| H7R20_RS24055 () | 61993..62558 | + | 566 | Protein_74 | class I SAM-dependent methyltransferase | - |
| H7R20_RS24060 () | 62584..62796 | + | 213 | WP_001348622.1 | hypothetical protein | - |
| H7R20_RS24065 () | 63206..63412 | + | 207 | WP_000275856.1 | hypothetical protein | - |
| H7R20_RS24070 () | 63438..63977 | + | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| H7R20_RS24075 () | 64045..64278 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| H7R20_RS24080 () | 64306..64503 | + | 198 | Protein_79 | hypothetical protein | - |
| H7R20_RS24085 () | 64558..64992 | + | 435 | WP_000845937.1 | conjugation system SOS inhibitor PsiB | - |
| H7R20_RS24090 () | 64989..65708 | + | 720 | WP_001276238.1 | plasmid SOS inhibition protein A | - |
| H7R20_RS24095 () | 65720..65908 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 65720..65910 | + | 191 | NuclAT_0 | - | - |
| - () | 65720..65910 | + | 191 | NuclAT_0 | - | - |
| - () | 65720..65910 | + | 191 | NuclAT_0 | - | - |
| - () | 65720..65910 | + | 191 | NuclAT_0 | - | - |
| H7R20_RS24100 () | 65958..67327 | + | 1370 | WP_085947770.1 | IS3-like element IS150 family transposase | - |
| - () | 67352..67390 | + | 39 | NuclAT_1 | - | - |
| - () | 67352..67390 | + | 39 | NuclAT_1 | - | - |
| - () | 67352..67390 | + | 39 | NuclAT_1 | - | - |
| - () | 67352..67390 | + | 39 | NuclAT_1 | - | - |
| H7R20_RS24105 () | 67434..67592 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H7R20_RS24110 () | 68513..68800 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| H7R20_RS24115 () | 68918..69739 | + | 822 | WP_001234426.1 | DUF945 domain-containing protein | - |
| H7R20_RS24120 () | 70036..70638 | - | 603 | WP_013362798.1 | transglycosylase SLT domain-containing protein | - |
| H7R20_RS24125 () | 70959..71342 | + | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| H7R20_RS24130 () | 71529..72218 | + | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| H7R20_RS24135 () | 72317..72712 | + | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| H7R20_RS24140 () | 72745..73110 | + | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| H7R20_RS24145 () | 73125..73436 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| H7R20_RS24150 () | 73458..74024 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| H7R20_RS24155 () | 74035..74739 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| H7R20_RS24160 () | 74739..76166 | + | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| H7R20_RS24165 () | 76156..76746 | + | 591 | WP_000002787.1 | conjugal transfer protein TraP | - |
| H7R20_RS24170 () | 76700..76930 | + | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| H7R20_RS24175 () | 76942..77193 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| H7R20_RS24180 () | 77190..77705 | + | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H7R20_RS24185 () | 77840..78061 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| H7R20_RS24190 () | 78221..80848 | + | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| H7R20_RS24195 () | 80845..81231 | + | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| H7R20_RS24200 () | 81228..81860 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| H7R20_RS24205 () | 81857..82849 | + | 993 | WP_000830180.1 | conjugal transfer pilus assembly protein TraU | - |
| H7R20_RS24210 () | 82858..83496 | + | 639 | WP_021518374.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H7R20_RS24215 () | 83493..85301 | + | 1809 | WP_000821840.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H7R20_RS24220 () | 85328..85585 | + | 258 | WP_000864312.1 | conjugal transfer protein TrbE | - |
| H7R20_RS24225 () | 85578..86321 | + | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H7R20_RS24230 () | 86335..86676 | + | 342 | WP_000556794.1 | conjugal transfer protein TrbA | - |
| H7R20_RS24235 () | 86657..86992 | - | 336 | WP_000415571.1 | hypothetical protein | - |
| H7R20_RS24240 () | 87073..87357 | + | 285 | WP_000624105.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H7R20_RS24245 () | 87344..87898 | + | 555 | WP_001553830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H7R20_RS24250 () | 87828..88202 | + | 375 | WP_071788165.1 | P-type conjugative transfer protein TrbJ | - |
| H7R20_RS24255 () | 88156..88548 | + | 393 | WP_000164675.1 | F-type conjugal transfer protein TrbF | - |
| H7R20_RS24260 () | 88535..89908 | + | 1374 | WP_021518370.1 | conjugal transfer protein TraH | - |
| H7R20_RS24265 () | 89905..92730 | + | 2826 | WP_001553826.1 | conjugal transfer mating pair stabilization protein TraG | - |
| H7R20_RS24270 () | 92727..93236 | + | 510 | WP_000628100.1 | conjugal transfer entry exclusion protein TraS | - |
| H7R20_RS24275 () | 93250..93981 | + | 732 | WP_000850424.1 | complement resistance protein TraT | - |
| H7R20_RS24280 () | 94233..96431 | + | 2199 | WP_046464200.1 | type IV conjugative transfer system coupling protein TraD | - |
| H7R20_RS24285 () | 96431..101551 | + | 5121 | WP_013362805.1 | conjugative transfer relaxase/helicase TraI | - |
| H7R20_RS24290 () | 101571..102317 | + | 747 | WP_023149624.1 | conjugal transfer pilus acetylase TraX | - |
| H7R20_RS24295 () | 102372..102932 | + | 561 | WP_000139363.1 | fertility inhibition protein FinO | - |
| H7R20_RS24300 () | 103066..103278 | + | 213 | WP_005012601.1 | hypothetical protein | - |
| H7R20_RS24305 () | 103579..103668 | - | 90 | Protein_124 | IS1 family transposase | - |
| H7R20_RS24310 () | 103723..104400 | + | 678 | WP_001339397.1 | IS66 family insertion sequence hypothetical protein | - |
| H7R20_RS24315 () | 104400..104747 | + | 348 | WP_000624622.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| H7R20_RS24320 () | 104767..106338 | + | 1572 | WP_023149734.1 | IS66 family transposase | - |
| H7R20_RS24325 () | 106376..106992 | - | 617 | Protein_128 | IS1 family transposase | - |
| H7R20_RS24330 () | 107093..107275 | + | 183 | WP_000968309.1 | hypothetical protein | - |
| - () | 107414..107475 | - | 62 | NuclAT_2 | - | - |
| - () | 107414..107475 | - | 62 | NuclAT_2 | - | - |
| - () | 107414..107475 | - | 62 | NuclAT_2 | - | - |
| - () | 107414..107475 | - | 62 | NuclAT_2 | - | - |
| H7R20_RS24335 () | 107462..107668 | + | 207 | WP_015387399.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H7R20_RS24340 () | 107952..108209 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| H7R20_RS24345 () | 108445..108519 | + | 75 | WP_032336874.1 | RepA leader peptide Tap | - |
| H7R20_RS24350 () | 108512..108958 | + | 447 | Protein_133 | incFII family plasmid replication initiator RepA | - |
| H7R20_RS24355 () | 108904..109386 | - | 483 | Protein_134 | VENN motif pre-toxin domain-containing protein | - |
| H7R20_RS24360 () | 110279..111499 | + | 1221 | WP_000410951.1 | arginine deiminase | - |
| H7R20_RS24365 () | 111510..112421 | + | 912 | WP_000440183.1 | carbamate kinase | - |
| H7R20_RS24370 () | 112506..113510 | + | 1005 | WP_000154545.1 | ornithine carbamoyltransferase | - |
| H7R20_RS24375 () | 113558..114961 | + | 1404 | WP_000514417.1 | YfcC family protein | - |
| H7R20_RS24380 () | 115042..115521 | + | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| H7R20_RS24385 () | 115585..115926 | - | 342 | Protein_140 | transposase | - |
| H7R20_RS24390 () | 115878..116099 | - | 222 | WP_000080227.1 | hypothetical protein | - |
| H7R20_RS24395 () | 116130..116480 | - | 351 | WP_000624725.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| H7R20_RS24400 () | 116477..116839 | - | 363 | WP_059330006.1 | IS66 family insertion sequence hypothetical protein | - |
| H7R20_RS24405 () | 116948..117645 | - | 698 | Protein_144 | IS1 family transposase | - |
| H7R20_RS24410 () | 117678..118256 | + | 579 | WP_032152936.1 | DUF2726 domain-containing protein | - |
| H7R20_RS24415 () | 118669..119022 | - | 354 | WP_000005489.1 | hypothetical protein | - |
| H7R20_RS24420 () | 119494..120516 | - | 1023 | WP_000156883.1 | IS110 family transposase | - |
| H7R20_RS24425 () | 120921..121178 | + | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| H7R20_RS24430 () | 121413..121487 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| H7R20_RS24435 () | 121480..122337 | + | 858 | WP_032152935.1 | incFII family plasmid replication initiator RepA | - |
| H7R20_RS24440 () | 123276..123929 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| H7R20_RS24445 () | 124022..124279 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| H7R20_RS24450 () | 124212..124613 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| H7R20_RS24455 () | 124898..126208 | + | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| H7R20_RS24460 () | 126237..126335 | + | 99 | Protein_155 | IS1 family transposase | - |
| H7R20_RS24465 () | 126485..127345 | - | 861 | WP_000027057.1 | class A broad-spectrum beta-lactamase TEM-1 | - |
| H7R20_RS24470 () | 127528..128085 | - | 558 | WP_001235713.1 | recombinase family protein | - |
| H7R20_RS24475 () | 128355..129059 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| H7R20_RS24480 () | 129124..129627 | + | 504 | Protein_159 | ATP-dependent endonuclease | - |
| H7R20_RS24485 () | 129612..130634 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| H7R20_RS24490 () | 130933..131630 | + | 698 | Protein_161 | IS1 family transposase | - |
| H7R20_RS24495 () | 131810..132323 | - | 514 | Protein_162 | DUF4113 domain-containing protein | - |
| H7R20_RS24500 () | 132384..132488 | - | 105 | Protein_163 | AAA family ATPase | - |
| H7R20_RS24505 () | 132490..132813 | - | 324 | Protein_164 | helix-turn-helix domain-containing protein | - |
| H7R20_RS24510 () | 133559..134536 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| H7R20_RS24515 () | 134821..135561 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| H7R20_RS24520 () | 135682..135870 | - | 189 | WP_001309252.1 | hypothetical protein | - |
| H7R20_RS24525 () | 136237..137406 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| H7R20_RS24530 () | 137632..137807 | - | 176 | Protein_169 | IS3 family transposase | - |
| H7R20_RS24535 () | 138253..138525 | - | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|