MGE detailed information
MGE type: Conjugative plasmid MGE length: 158291 bp
Accession: NZ_AP022121 Location: 1..158291 Organism: Escherichia coli strain WP5-W18-ESBL-11 Replicon: plasmid pWP5-W18-ESBL-11_1
Accession: NZ_AP022121 Location: 1..158291 Organism: Escherichia coli strain WP5-W18-ESBL-11 Replicon: plasmid pWP5-W18-ESBL-11_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7R04_RS22745 () | 101..1054 | + | 954 | WP_000280980.1 | Protease 7 | VF |
| H7R04_RS22750 () | 1487..2596 | + | 1110 | WP_182913205.1 | SDR family oxidoreductase | - |
| H7R04_RS22755 () | 2665..3567 | + | 903 | WP_001312822.1 | hypothetical protein | VF |
| H7R04_RS22760 () | 3941..4129 | + | 189 | WP_001324033.1 | hypothetical protein | - |
| H7R04_RS22765 () | 4250..4990 | + | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| H7R04_RS22770 () | 5275..6252 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| H7R04_RS22775 () | 6998..7321 | + | 324 | Protein_6 | IS21 family transposase IS21 | Transposase |
| H7R04_RS22780 () | 7323..7427 | + | 105 | Protein_7 | AAA family ATPase | - |
| H7R04_RS22785 () | 7488..8001 | + | 514 | Protein_8 | DUF4113 domain-containing protein | - |
| H7R04_RS22790 () | 8181..8878 | - | 698 | Protein_9 | IS1 family transposase IS1S | Transposase |
| H7R04_RS22795 () | 9234..10148 | + | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| H7R04_RS22800 () | 10148..10975 | + | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| H7R04_RS22805 () | 10972..11829 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| H7R04_RS22810 () | 11826..12683 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| H7R04_RS22815 () | 13172..13585 | + | 414 | Protein_14 | phosphopyruvate hydratase | - |
| H7R04_RS22820 () | 13926..14306 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| H7R04_RS22825 () | 14686..15879 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| H7R04_RS22830 () | 16015..17739 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| H7R04_RS22835 () | 17740..18687 | + | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| H7R04_RS22840 () | 18687..20429 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| H7R04_RS22845 () | 20426..21703 | + | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| H7R04_RS22850 () | 21785..23986 | + | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| H7R04_RS22855 () | 24366..25063 | + | 698 | Protein_22 | IS1 family transposase IS1S | Transposase |
| H7R04_RS22860 () | 25317..26339 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| H7R04_RS22865 () | 26324..27889 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| H7R04_RS22870 () | 27964..28380 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| H7R04_RS22875 () | 28377..28607 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| H7R04_RS22880 () | 28988..32782 | + | 3795 | WP_001144731.1 | hypothetical protein | - |
| H7R04_RS22885 () | 32827..33243 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| H7R04_RS22890 () | 33240..33470 | - | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| H7R04_RS22895 () | 33735..34235 | + | 501 | WP_000528932.1 | hypothetical protein | - |
| H7R04_RS22900 () | 34248..35021 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| H7R04_RS22905 () | 35188..36321 | + | 1134 | WP_000545984.1 | DUF3800 domain-containing protein | - |
| H7R04_RS22910 () | 36355..36867 | - | 513 | WP_000151784.1 | hypothetical protein | - |
| H7R04_RS22915 () | 37435..37653 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| H7R04_RS22920 () | 37655..37960 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| H7R04_RS22925 () | 37961..38767 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| H7R04_RS22930 () | 39519..40274 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| H7R04_RS22935 () | 40862..42028 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| H7R04_RS22940 () | 42028..42999 | + | 972 | WP_000817035.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| H7R04_RS22945 () | 43909..44810 | + | 902 | Protein_40 | DUF1281 domain-containing protein | - |
| H7R04_RS22950 () | 44814..45119 | + | 306 | WP_010891292.1 | hypothetical protein | - |
| H7R04_RS22955 () | 45196..45879 | + | 684 | WP_000085939.1 | DNA methylase | - |
| H7R04_RS22960 () | 45880..46101 | + | 222 | WP_001104870.1 | hypothetical protein | - |
| H7R04_RS22965 () | 45995..46549 | + | 555 | WP_077248347.1 | DUF1380 family protein | - |
| H7R04_RS22970 () | 46595..47371 | + | 777 | WP_001005035.1 | hypothetical protein | - |
| H7R04_RS22975 () | 47907..48209 | + | 303 | WP_072148062.1 | antirestriction protein | - |
| H7R04_RS22980 () | 48256..48678 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
| H7R04_RS22985 () | 48675..48866 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| H7R04_RS22990 () | 48836..49345 | - | 510 | WP_071600123.1 | hypothetical protein | - |
| H7R04_RS22995 () | 49663..50202 | + | 540 | WP_000290801.1 | single-stranded DNA-binding protein | - |
| H7R04_RS23000 () | 50259..50492 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| H7R04_RS23005 () | 50558..52516 | + | 1959 | WP_029487628.1 | ParB/RepB/Spo0J family partition protein | - |
| H7R04_RS23010 () | 52571..53005 | + | 435 | WP_000845928.1 | conjugation system SOS inhibitor PsiB | - |
| H7R04_RS23015 () | 53002..53721 | + | 720 | WP_000116348.1 | plasmid SOS inhibition protein A | - |
| - () | 53733..53931 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 53733..53931 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 53733..53931 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 53733..53931 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| H7R04_RS23020 () | 53996..54154 | + | 159 | WP_001302184.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H7R04_RS23025 () | 54392..54751 | - | 360 | Protein_56 | hypothetical protein | - |
| H7R04_RS23030 () | 54821..55027 | + | 207 | WP_000547965.1 | hypothetical protein | - |
| H7R04_RS23035 () | 55052..55339 | + | 288 | WP_000107546.1 | hypothetical protein | - |
| H7R04_RS23040 () | 55458..56279 | + | 822 | WP_001234475.1 | DUF945 domain-containing protein | - |
| H7R04_RS23045 () | 56574..57164 | - | 591 | WP_166494936.1 | hypothetical protein | VF |
| H7R04_RS23050 () | 57516..57899 | + | 384 | WP_001063020.1 | relaxosome protein TraM | - |
| H7R04_RS23055 () | 58091..58738 | + | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| H7R04_RS23060 () | 58874..59089 | + | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| H7R04_RS23065 () | 59132..59497 | + | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| H7R04_RS23070 () | 59512..59823 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| H7R04_RS23075 () | 59845..60411 | + | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| H7R04_RS23080 () | 60422..61126 | + | 705 | WP_148713163.1 | type-F conjugative transfer system secretin TraK | - |
| H7R04_RS23085 () | 61126..62553 | + | 1428 | WP_000146676.1 | conjugal transfer protein TraB | - |
| H7R04_RS23090 () | 62543..63133 | + | 591 | WP_000002787.1 | conjugal transfer protein TraP | - |
| H7R04_RS23095 () | 63087..63317 | + | 231 | WP_001442573.1 | conjugal transfer protein TrbD | - |
| H7R04_RS23100 () | 63329..63580 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| H7R04_RS23105 () | 63577..64092 | + | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H7R04_RS23110 () | 64227..64448 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| H7R04_RS23115 () | 64608..67235 | + | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| H7R04_RS23120 () | 67232..67618 | + | 387 | WP_000099691.1 | type-F conjugative transfer system protein TrbI | - |
| H7R04_RS23125 () | 67615..68247 | + | 633 | WP_001203717.1 | type-F conjugative transfer system protein TraW | - |
| H7R04_RS23130 () | 68244..69236 | + | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| H7R04_RS23135 () | 69245..69883 | + | 639 | WP_000777695.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H7R04_RS23140 () | 69880..71688 | + | 1809 | WP_000821838.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H7R04_RS23145 () | 71715..71972 | + | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| H7R04_RS23150 () | 71965..72708 | + | 744 | WP_001030377.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H7R04_RS23155 () | 72724..73071 | + | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| H7R04_RS23160 () | 73073..73387 | - | 315 | WP_001324103.1 | hypothetical protein | - |
| H7R04_RS23165 () | 73468..73752 | + | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H7R04_RS23170 () | 73739..74284 | + | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H7R04_RS23175 () | 74214..74555 | + | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| H7R04_RS23180 () | 74509..74922 | + | 414 | WP_001324104.1 | F-type conjugal transfer protein TrbF | - |
| H7R04_RS23185 () | 74922..76295 | + | 1374 | WP_001517790.1 | conjugal transfer protein TraH | - |
| H7R04_RS23190 () | 76292..79114 | + | 2823 | WP_001007018.1 | conjugal transfer mating pair stabilization protein TraG | - |
| H7R04_RS23195 () | 79130..79627 | + | 498 | WP_000605857.1 | entry exclusion protein | - |
| H7R04_RS23200 () | 79659..80390 | + | 732 | WP_023565183.1 | complement resistance protein TraT | - |
| H7R04_RS23205 () | 80643..82796 | + | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| H7R04_RS23210 () | 82805..83203 | - | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| H7R04_RS23215 () | 83203..83430 | - | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| H7R04_RS23220 () | 83512..88782 | + | 5271 | WP_000986963.1 | Multifunctional conjugation protein TraI | Relaxase |
| H7R04_RS23225 () | 88802..89548 | + | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| H7R04_RS23230 () | 89607..90467 | + | 861 | WP_000704513.1 | putative protein YcjY | VF |
| H7R04_RS23235 () | 90570..91130 | + | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| H7R04_RS23240 () | 91266..91478 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| H7R04_RS23245 () | 91724..91798 | + | 75 | Protein_100 | endonuclease | - |
| - () | 92054..92115 | - | 62 | NuclAT_1 | - | - |
| - () | 92054..92115 | - | 62 | NuclAT_1 | - | - |
| - () | 92054..92115 | - | 62 | NuclAT_1 | - | - |
| - () | 92054..92115 | - | 62 | NuclAT_1 | - | - |
| H7R04_RS23250 () | 92102..92308 | + | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | - |
| H7R04_RS23255 () | 92592..92849 | + | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| H7R04_RS23260 () | 93081..93155 | + | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| H7R04_RS23265 () | 93148..93630 | + | 483 | WP_001273588.1 | hypothetical protein | - |
| H7R04_RS23270 () | 93623..94088 | + | 466 | Protein_105 | incFII family plasmid replication initiator RepA | - |
| H7R04_RS23275 () | 94021..97026 | - | 3006 | WP_001143760.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| H7R04_RS23280 () | 97190..97747 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| H7R04_RS23285 () | 97930..98790 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| H7R04_RS23290 () | 99067..100644 | - | 1578 | WP_001323889.1 | Aerotaxis receptor | VF |
| H7R04_RS23295 () | 100954..101514 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| H7R04_RS23300 () | 101518..104484 | + | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| H7R04_RS23305 () | 105342..105686 | + | 345 | WP_001553768.1 | hypothetical protein | - |
| H7R04_RS23310 () | 105867..106982 | - | 1116 | Protein_113 | IS91 family transposase IS91 | Transposase |
| H7R04_RS23315 () | 106982..107347 | - | 366 | WP_000124098.1 | hypothetical protein | - |
| H7R04_RS23320 () | 107469..108620 | - | 1152 | WP_001442799.1 | IS30 family transposase IS30D | Transposase |
| H7R04_RS23325 () | 108688..108945 | - | 258 | Protein_116 | IS3 family transposase IS911 | Transposase |
| H7R04_RS23330 () | 109041..109395 | + | 355 | Protein_117 | helix-turn-helix transcriptional regulator | - |
| H7R04_RS23335 () | 109586..113719 | + | 4134 | WP_001080137.1 | Temperature-sensitive hemagglutinin tsh autotransporter | VF |
| H7R04_RS23340 () | 113828..114280 | + | 453 | WP_001553770.1 | peptide deformylase | - |
| H7R04_RS23345 () | 114267..114533 | - | 267 | Protein_120 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| H7R04_RS23350 () | 114573..116110 | - | 1538 | Protein_121 | IS66 family transposase ISEc8 | Transposase |
| H7R04_RS23355 () | 116160..116507 | - | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| H7R04_RS23360 () | 116504..116884 | - | 381 | WP_001171523.1 | IS66 family transposase ISEc8 | Transposase |
| H7R04_RS23365 () | 116960..117940 | - | 981 | WP_001017346.1 | NAD(P)-binding domain-containing protein | - |
| H7R04_RS23370 () | 117937..118206 | - | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| H7R04_RS23375 () | 118208..118985 | - | 778 | Protein_126 | Gfo/Idh/MocA family oxidoreductase | - |
| H7R04_RS23380 () | 119146..119382 | + | 237 | WP_001323890.1 | colicin V immunity protein | - |
| H7R04_RS23385 () | 119360..119671 | + | 312 | WP_001259758.1 | colicin V | - |
| H7R04_RS23390 () | 119841..121955 | - | 2115 | WP_001183604.1 | peptidase domain-containing ABC transporter | - |
| H7R04_RS23395 () | 121930..123204 | - | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| H7R04_RS23400 () | 123886..124083 | + | 198 | WP_001324224.1 | toxin-antitoxin system protein | Antitoxin Detail |
| H7R04_RS23405 () | 124080..124262 | + | 183 | WP_000969988.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| H7R04_RS23410 () | 124361..124669 | + | 309 | WP_000377483.1 | hypothetical protein | - |
| H7R04_RS23415 () | 125229..126263 | + | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| H7R04_RS23420 () | 127129..129306 | + | 2178 | WP_001222185.1 | Ferric enterobactin receptor | VF |
| H7R04_RS23425 () | 129351..130307 | - | 957 | WP_000271274.1 | Ferri-bacillibactin esterase BesA | VF |
| H7R04_RS23430 () | 130392..131621 | - | 1230 | WP_000933678.1 | Enterochelin esterase | VF |
| H7R04_RS23435 () | 131725..135384 | - | 3660 | WP_001389363.1 | Multidrug efflux ATP-binding/permease protein | VF |
| H7R04_RS23440 () | 135524..136639 | - | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| H7R04_RS23445 () | 137875..138974 | - | 1100 | Protein_140 | IS481 family transposase ISKpn28 | Transposase |
| H7R04_RS23450 () | 139528..139727 | + | 200 | Protein_141 | lysis protein | - |
| H7R04_RS23455 () | 139785..140078 | - | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| H7R04_RS23460 () | 140658..141223 | + | 566 | Protein_143 | IS3 family transposase IS2 | Transposase |
| H7R04_RS23470 () | 142464..143192 | + | 729 | Protein_145 | IS3 family transposase IS2 | Transposase |
| H7R04_RS23475 () | 144434..145627 | + | 1194 | WP_000450494.1 | GTP-binding protein | - |
| H7R04_RS23480 () | 145805..145954 | + | 150 | Protein_147 | IS3 family transposase IS2 | Transposase |
| H7R04_RS23485 () | 146264..147653 | + | 1390 | Protein_148 | ISNCY family transposase ISKpn21 | Transposase |
| H7R04_RS23490 () | 147888..148829 | + | 942 | WP_000974762.1 | hypothetical protein | - |
| H7R04_RS23495 () | 148958..149152 | - | 195 | Protein_150 | IS200/IS605-like element IS200C family transposase | - |
| H7R04_RS23500 () | 149626..150996 | - | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| H7R04_RS23505 () | 151000..152940 | - | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| H7R04_RS23510 () | 152937..154124 | - | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| H7R04_RS23515 () | 155105..155430 | + | 326 | Protein_154 | IS3 family transposase ISLad1 | Transposase |
| H7R04_RS23520 () | 155578..156777 | - | 1200 | Protein_155 | IS3 family transposase IS629 | Transposase |
| H7R04_RS23525 () | 156961..157119 | + | 159 | WP_001324039.1 | integrase core domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|