MGE detailed information

MGE type: Conjugative plasmid        MGE length: 183772 bp
Accession: NZ_AP022088        Location: 1..183772         Organism: Escherichia coli strain WP4-S18-ESBL-07       Replicon: plasmid pWP4-S18-ESBL-07_1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R53_RS23510 () 101..1315 + 1215 WP_085326192.1 DeoR family transcriptional regulator -
H7R53_RS23515 () 1329..2087 + 759 WP_001066367.1 hypothetical protein -
H7R53_RS23520 () 2178..3112 + 935 Protein_2 DMT family transporter -
H7R53_RS23525 () 3115..4150 + 1036 Protein_3 phosphotriesterase -
H7R53_RS23530 () 4573..4854 - 282 WP_085326188.1 hypothetical protein -
H7R53_RS23535 () 4960..5235 - 276 WP_085326186.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
H7R53_RS23540 () 5235..5519 - 285 WP_085008810.1 ribbon-helix-helix protein, CopG family Antitoxin Detail
H7R53_RS23545 () 5949..6050 + 102 Protein_7 IS66 family insertion sequence element accessory protein TnpB -
H7R53_RS23550 () 6543..7706 - 1164 WP_085326184.1 hypothetical protein -
H7R53_RS23555 () 7703..10462 - 2760 WP_085326182.1 Dimodular nonribosomal peptide synthase VF
H7R53_RS23560 () 10544..12640 - 2097 WP_085326180.1 TonB-dependent receptor -
H7R53_RS23565 () 12793..13776 - 984 WP_085326178.1 Ferric enterobactin transport system permease protein FepG VF
H7R53_RS23570 () 13773..14786 - 1014 WP_137475307.1 putative siderophore transport system permease protein YfiZ VF
H7R53_RS23575 () 14788..15729 - 942 WP_000263361.1 Ferrienterobactin-binding periplasmic protein VF
H7R53_RS23580 () 15973..20367 + 4395 WP_137475306.1 Anguibactin system regulator VF
H7R53_RS23585 () 20412..21746 - 1335 WP_085326174.1 hypothetical protein -
H7R53_RS23590 () 22244..22434 - 191 Protein_16 transposase -
H7R53_RS23595 () 22434..22502 + 69 Protein_17 IS200/IS605 family transposase -
H7R53_RS23600 () 22486..23184 - 699 WP_085326172.1 helix-turn-helix domain-containing protein -
H7R53_RS23605 () 24186..24773 + 588 WP_072645656.1 proQ/FINO family protein -
H7R53_RS23610 () 25053..25640 - 588 WP_064550130.1 colanic acid biosynthesis acetyltransferase -
H7R53_RS23615 () 26406..26951 - 546 WP_170852536.1 hypothetical protein -
H7R53_RS23620 () 26961..27248 - 288 WP_001523468.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
H7R53_RS23625 () 27245..27496 - 252 WP_001139206.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
H7R53_RS23630 () 27583..27750 - 168 WP_072645565.1 hypothetical protein -
H7R53_RS23635 () 28450..29472 - 1023 WP_085008816.1 replication initiation protein -
H7R53_RS23640 () 30433..30680 + 248 Protein_26 hypothetical protein -
H7R53_RS23645 () 31326..31859 + 534 WP_001372168.1 transcription termination factor NusG -
H7R53_RS23650 () 32113..32796 + 684 WP_085326168.1 conjugal transfer protein TraC -
H7R53_RS23655 () 32810..33376 + 567 WP_072645570.1 conjugal transfer protein TraD -
H7R53_RS23660 () 33644..33898 + 255 WP_085326164.1 PilI type IV pilus biogenesis protein -
H7R53_RS23665 () 33941..34422 + 482 Protein_31 pili assembly chaperone -
H7R53_RS23670 () 35068..36135 + 1068 WP_085326160.1 hypothetical protein VF
H7R53_RS23675 () 36135..36572 + 438 WP_000539811.1 hypothetical protein VF
H7R53_RS23680 () 36586..38268 + 1683 WP_000748143.1 Outer membrane lipoprotein BfpB VF
H7R53_RS23685 () 38261..39556 + 1296 WP_085326158.1 type 4b pilus protein PilO2 -
H7R53_RS23690 () 39543..39995 + 453 WP_182920553.1 hypothetical protein VF
H7R53_RS23695 () 40006..41559 + 1554 WP_085326156.1 Toxin coregulated pilus biosynthesis protein T VF
H7R53_RS23700 () 41572..42657 + 1086 WP_063103211.1 Toxin coregulated pilus biosynthesis protein E VF
H7R53_RS23705 () 42674..43288 + 615 WP_072645204.1 hypothetical protein VF
H7R53_RS23710 () 43298..43858 + 561 WP_072645203.1 hypothetical protein VF
H7R53_RS23715 () 43843..44499 + 657 WP_085326154.1 hypothetical protein VF
H7R53_RS23720 () 44487..45800 + 1314 WP_182920554.1 hypothetical protein VF
H7R53_RS23725 () 46096..46293 + 198 WP_137475287.1 prepilin -
H7R53_RS23730 () 46290..46538 - 249 WP_114141349.1 hypothetical protein -
H7R53_RS23735 () 46668..47021 - 354 WP_112029616.1 shufflon protein D' -
H7R53_RS23740 () 47020..48174 + 1155 WP_072645288.1 integrase -
H7R53_RS23745 () 48325..49149 + 825 WP_072645285.1 conjugal transfer protein TraE -
H7R53_RS23750 () 49235..50437 + 1203 WP_072645284.1 conjugal transfer protein TraF -
H7R53_RS23755 () 50563..51771 + 1209 WP_072645283.1 IS200-IS605 family transposase IS609 Transposase
H7R53_RS23760 () 52192..52650 + 459 WP_085326088.1 hypothetical protein VF
H7R53_RS23765 () 52647..53465 + 819 WP_077127683.1 hypothetical protein VF
H7R53_RS23770 () 53462..54610 + 1149 WP_001024975.1 putative protein YggR VF
H7R53_RS23775 () 54607..54897 + 291 WP_001299214.1 hypothetical protein -
H7R53_RS23780 () 54912..55463 + 552 WP_000014581.1 Phospholipase D VF
H7R53_RS23785 () 55553..59320 + 3768 WP_085326090.1 DNA primase -
H7R53_RS23790 () 59338..59685 + 348 WP_001055900.1 conjugal transfer protein -
H7R53_RS23795 () 59682..60374 + 693 WP_000138549.1 DotI/IcmL family type IV secretion protein -
H7R53_RS23800 () 60385..61368 + 984 WP_001191879.1 hypothetical protein VF
H7R53_RS23805 () 61371..62660 + 1290 WP_085326092.1 conjugal transfer protein TraO -
H7R53_RS23810 () 62660..63364 + 705 WP_000801920.1 IncI1-type conjugal transfer protein TraP -
H7R53_RS23815 () 63364..63891 + 528 WP_001055569.1 conjugal transfer protein TraQ -
H7R53_RS23820 () 63942..64346 + 405 WP_001422824.1 IncI1-type conjugal transfer protein TraR -
H7R53_RS23825 () 64410..64598 + 189 WP_001277255.1 putative conjugal transfer protein TraS -
H7R53_RS23830 () 64582..65382 + 801 WP_001164788.1 IncI1-type conjugal transfer protein TraT -
H7R53_RS23835 () 65472..68516 + 3045 WP_085326094.1 IncI1-type conjugal transfer protein TraU -
H7R53_RS23840 () 68516..69130 + 615 WP_072645276.1 IncI1-type conjugal transfer protein TraV -
H7R53_RS23845 () 69097..70299 + 1203 WP_052938672.1 IncI1-type conjugal transfer protein TraW -
H7R53_RS23850 () 70328..70912 + 585 WP_085008864.1 conjugal transfer protein TraX -
H7R53_RS23855 () 71009..73177 + 2169 WP_182920555.1 DotA/TraY family protein -
H7R53_RS23860 () 73242..73904 + 663 WP_001542510.1 plasmid IncI1-type surface exclusion protein ExcA -
H7R53_RS23865 () 74002..74211 + 210 WP_001140544.1 hemolysin expression modulator Hha -
H7R53_RS23870 () 74420..74596 + 177 WP_001054905.1 hypothetical protein -
H7R53_RS23875 () 75501..75752 + 252 WP_001618083.1 hypothetical protein -
H7R53_RS23880 () 75824..75976 - 153 WP_001331364.1 Hok/Gef family protein Toxin Detail
- () 76026..76088 + 63 NuclAT_1 - -
- () 76026..76088 + 63 NuclAT_1 - -
- () 76026..76088 + 63 NuclAT_1 - -
- () 76026..76088 + 63 NuclAT_1 - -
H7R53_RS23885 () 76268..77476 + 1209 WP_182920556.1 IncI1-type conjugal transfer protein TrbA -
H7R53_RS23890 () 77495..78565 + 1071 WP_000151586.1 IncI1-type conjugal transfer protein TrbB -
H7R53_RS23895 () 78558..80849 + 2292 WP_085326102.1 conjugal transfer protein TrbC -
H7R53_RS23900 () 80991..81653 - 663 WP_000835776.1 PAS domain-containing protein -
H7R53_RS23905 () 81839..82798 + 960 WP_085326104.1 sugar phosphate isomerase/epimerase -
H7R53_RS23910 () 82820..83197 + 378 WP_001559792.1 RidA family protein -
H7R53_RS23915 () 83213..84445 + 1233 WP_001045917.1 MFS transporter -
H7R53_RS23920 () 84603..87302 - 2700 WP_085326106.1 Protein TraI Relaxase
H7R53_RS23925 () 87313..87645 - 333 WP_001281051.1 hypothetical protein -
H7R53_RS23930 () 87880..88227 + 348 WP_085326108.1 molybdopterin-guanine dinucleotide biosynthesis protein MobC -
H7R53_RS23935 () 88238..88423 - 186 WP_085326110.1 hypothetical protein -
H7R53_RS23940 () 88834..89154 + 321 WP_050869027.1 hypothetical protein -
H7R53_RS23945 () 89426..89677 + 252 WP_182920557.1 helix-turn-helix domain-containing protein -
H7R53_RS23950 () 89708..89953 - 246 WP_001260884.1 hypothetical protein -
H7R53_RS23955 () 89953..90867 - 915 WP_000038334.1 Recombination-promoting nuclease RpnA VF
H7R53_RS23960 () 90932..91198 - 267 WP_001247862.1 hypothetical protein -
H7R53_RS23965 () 91293..91727 - 435 WP_000218858.1 hypothetical protein -
H7R53_RS23970 () 92455..92955 - 501 WP_085326112.1 antirestriction protein ArdA -
H7R53_RS26105 () 93418..93615 - 198 Protein_93 hypothetical protein -
H7R53_RS23975 () 93695..94099 - 405 WP_001175008.1 IS200-IS605 family transposase ISSen6 Transposase
H7R53_RS23980 () 94158..95384 + 1227 WP_182920558.1 IS200-IS605 family transposase ISSen6 Transposase
H7R53_RS23985 () 95684..96187 + 504 WP_085326126.1 GNAT family N-acetyltransferase -
H7R53_RS23990 () 96382..96543 - 162 WP_000775238.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 96589..96797 - 209 NuclAT_0 - -
- () 96589..96797 - 209 NuclAT_0 - -
- () 96589..96797 - 209 NuclAT_0 - -
- () 96589..96797 - 209 NuclAT_0 - -
H7R53_RS23995 () 96809..97528 - 720 WP_072645262.1 plasmid SOS inhibition protein A -
H7R53_RS24000 () 97525..97959 - 435 WP_085326114.1 conjugation system SOS inhibitor PsiB -
H7R53_RS24005 () 98014..99972 - 1959 WP_182920546.1 ParB/RepB/Spo0J family partition protein -
H7R53_RS24010 () 100036..100269 - 234 WP_021564200.1 DUF905 family protein -
H7R53_RS24015 () 100327..100854 - 528 WP_001276114.1 single-stranded DNA-binding protein -
H7R53_RS24020 () 101223..101291 + 69 Protein_103 pilus protein -
H7R53_RS24025 () 101624..101815 - 192 WP_085326118.1 hypothetical protein -
H7R53_RS24030 () 101812..102234 - 423 WP_085326120.1 DUF1380 family protein -
H7R53_RS24035 () 102281..102583 - 303 WP_014653258.1 antirestriction protein -
H7R53_RS24040 () 103123..103899 - 777 WP_175154176.1 hypothetical protein -
H7R53_RS24045 () 103950..104369 - 420 WP_072645426.1 DUF1380 family protein -
H7R53_RS24050 () 104382..104603 - 222 WP_001104892.1 hypothetical protein -
H7R53_RS24055 () 104604..104783 - 180 Protein_110 DNA methylase -
H7R53_RS24060 () 104904..105848 + 945 WP_071604158.1 tyrosine-type recombinase/integrase -
H7R53_RS24065 () 105845..106771 + 927 WP_024216355.1 tyrosine-type recombinase/integrase -
H7R53_RS24070 () 106764..107777 + 1014 WP_024216356.1 tyrosine-type recombinase/integrase -
H7R53_RS24075 () 107971..108546 + 576 WP_024216357.1 hypothetical protein -
H7R53_RS24080 () 108705..109223 - 519 WP_182920547.1 adenine-specific DNA-methyltransferase -
H7R53_RS24085 () 109300..109610 - 311 Protein_116 hypothetical protein -
H7R53_RS24090 () 109607..110509 - 903 WP_139814908.1 DUF1281 domain-containing protein -
H7R53_RS24095 () 110927..111175 + 249 WP_000618110.1 DinI-like family protein -
H7R53_RS24100 () 111172..111609 + 438 WP_000109071.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
H7R53_RS24105 () 111609..112883 + 1275 WP_085326124.1 Y-family DNA polymerase -
H7R53_RS24110 () 112885..113301 - 417 WP_072645021.1 plasmid partitioning/stability family protein -
H7R53_RS24115 () 113294..114274 - 981 WP_072645020.1 plasmid segregation protein ParM -
H7R53_RS24120 () 114682..114990 - 309 WP_000030199.1 hypothetical protein -
H7R53_RS24125 () 115077..115721 - 645 WP_001144036.1 ParA family protein -
H7R53_RS24130 () 115900..116244 - 345 Protein_125 tyrosine-type recombinase/integrase -
H7R53_RS24135 () 116297..117523 - 1227 WP_182920558.1 IS200-IS605 family transposase ISSen6 Transposase
H7R53_RS24140 () 117582..117986 + 405 WP_001175008.1 IS200-IS605 family transposase ISSen6 Transposase
H7R53_RS24145 () 118063..118497 - 435 Protein_128 tyrosine-type recombinase/integrase -
H7R53_RS24150 () 118499..118912 - 414 WP_085326342.1 hypothetical protein -
H7R53_RS24155 () 119819..120796 + 978 WP_000361618.1 RepB family plasmid replication initiator protein -
H7R53_RS24160 () 121081..121821 - 741 WP_085326340.1 tyrosine-type recombinase/integrase -
H7R53_RS24165 () 123446..124102 + 657 WP_077250687.1 PIG-L family deacetylase -
H7R53_RS24170 () 124116..125312 + 1197 WP_072645011.1 glycosyltransferase family 2 protein -
H7R53_RS24175 () 125290..125871 + 582 WP_072645023.1 acetyltransferase -
H7R53_RS24180 () 125873..126646 + 774 WP_072645010.1 YaiO family outer membrane beta-barrel protein -
H7R53_RS24185 () 126829..127077 - 249 WP_137475127.1 PerC family transcriptional regulator -
H7R53_RS24190 () 127117..127424 - 308 Protein_137 ParB/RepB/Spo0J family partition protein -
H7R53_RS24195 () 127442..128607 - 1166 Protein_138 IS3 family transposase ISKpn37 Transposase
H7R53_RS24200 () 128856..131003 + 2148 WP_085326330.1 TonB-dependent receptor -
H7R53_RS24205 () 131374..132018 - 645 WP_182920548.1 ParB N-terminal domain-containing protein -
H7R53_RS24210 () 132003..133235 - 1233 WP_085326382.1 phosphoadenosine phosphosulfate reductase -
H7R53_RS24215 () 133225..133359 - 135 WP_000065644.1 hypothetical protein VF
H7R53_RS26110 () 133406..133579 - 174 Protein_143 serine hydrolase -
H7R53_RS24220 () 133650..134007 - 358 Protein_144 hypothetical protein -
H7R53_RS24225 () 134666..136042 + 1377 WP_182920549.1 argininosuccinate lyase -
H7R53_RS24230 () 136107..137423 + 1317 WP_085326384.1 anaerobic C4-dicarboxylate transporter -
H7R53_RS24235 () 137539..138855 - 1317 WP_142456063.1 anaerobic C4-dicarboxylate transporter -
H7R53_RS24240 () 139021..139677 + 657 WP_072645006.1 FadR family transcriptional regulator -
H7R53_RS24245 () 140656..141381 + 726 WP_085325883.1 two-component system response regulator DcuR -
H7R53_RS24250 () 141894..142940 - 1047 WP_001012364.1 L-asparaginase 2 -
H7R53_RS24255 () 143428..144762 - 1335 WP_000351505.1 anaerobic C4-dicarboxylate transporter -
H7R53_RS24260 () 144918..146318 - 1401 WP_000086499.1 aspartate ammonia-lyase -
H7R53_RS24265 () 147193..148449 + 1257 WP_072645540.1 peptidase T -
H7R53_RS24270 () 148446..149807 + 1362 WP_001595909.1 C4-dicarboxylate transporter DcuC -
H7R53_RS26125 () 149860..149988 - 129 Protein_155 transposase -
H7R53_RS24280 () 150453..151361 + 909 Protein_156 group II intron reverse transcriptase/maturase -
H7R53_RS24285 () 151767..152798 + 1032 WP_094320497.1 isoaspartyl peptidase/L-asparaginase -
H7R53_RS24290 () 153137..153415 - 279 WP_000849708.1 DUF5339 domain-containing protein -
H7R53_RS24295 () 153861..154312 + 452 Protein_159 IS256 family transposase ISSoEn2 Transposase
H7R53_RS24300 () 154513..155225 - 713 Protein_160 Protein SapB VF
H7R53_RS24305 () 155289..156308 - 1020 WP_000671481.1 nucleoside hydrolase -
H7R53_RS24310 () 156283..157314 - 1032 WP_000194408.1 LacI family transcriptional regulator -
H7R53_RS24315 () 157419..158813 - 1395 WP_001091891.1 MHS family MFS transporter -
H7R53_RS24320 () 159106..159823 + 718 Protein_164 DUF932 domain-containing protein -
H7R53_RS24325 () 159866..160072 + 207 WP_170916088.1 hypothetical protein -
H7R53_RS24330 () 160086..160586 + 501 Protein_166 IS200/IS605 family transposase -
H7R53_RS26115 () 161200..161651 + 452 Protein_167 transposase -
H7R53_RS24345 () 162176..163078 + 903 WP_085326360.1 2-dehydro-3-deoxygalactonokinase -
H7R53_RS24350 () 163075..163719 + 645 WP_085326362.1 2-dehydro-3-deoxy-6-phosphogalactonate aldolase -
H7R53_RS24355 () 163923..165278 + 1356 WP_182920550.1 MFS transporter -
H7R53_RS24360 () 165298..167010 + 1713 WP_182920551.1 dihydroxy-acid dehydratase -
H7R53_RS24365 () 167007..167915 + 909 WP_085326368.1 dihydrodipicolinate synthase family protein -
H7R53_RS24370 () 168164..168370 - 207 WP_170916092.1 hypothetical protein -
H7R53_RS24375 () 168538..169269 - 732 WP_085326372.1 FadR family transcriptional regulator -
H7R53_RS24380 () 169579..169836 + 258 Protein_175 hypothetical protein -
H7R53_RS26120 () 169927..170182 + 256 Protein_176 molecular chaperone GroEL -
H7R53_RS24385 () 170632..170930 + 299 Protein_177 IS66 family transposase ISEc23 Transposase
H7R53_RS24390 () 171317..172006 + 690 WP_000174305.1 D-galactonate utilization transcriptional regulator DgoR -
H7R53_RS24395 () 172003..172881 + 879 WP_182920552.1 2-dehydro-3-deoxygalactonokinase -
H7R53_RS24400 () 172865..173482 + 618 WP_072648232.1 2-dehydro-3-deoxy-6-phosphogalactonate aldolase -
H7R53_RS24405 () 173479..174627 + 1149 WP_085007881.1 galactonate dehydratase -
H7R53_RS24410 () 174702..176039 + 1338 WP_162722313.1 MFS transporter -
H7R53_RS24415 () 176233..176733 - 501 Protein_183 IS200-IS605 family transposase IS200C Transposase
H7R53_RS24420 () 177393..178292 - 900 WP_000789107.1 hypochlorite stress DNA-binding transcriptional regulator HypT -
H7R53_RS24425 () 178632..179349 + 718 Protein_185 amino acid racemase -
H7R53_RS24430 () 179408..180706 + 1299 WP_072645474.1 anaerobic C4-dicarboxylate transporter -
H7R53_RS24435 () 180929..182329 + 1401 WP_000086499.1 aspartate ammonia-lyase -
H7R53_RS24440 () 182565..183256 - 692 Protein_188 IS3 family transposase -
H7R53_RS24445 () 183318..183677 + 360 Protein_189 transposase -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance