MGE detailed information
MGE type: Conjugative plasmid MGE length: 77891 bp
Accession: NZ_AP022072 Location: 1..77891 Organism: Escherichia coli strain WP4-W18-ESBL-09 Replicon: plasmid pWP4-W18-ESBL-09_3
Accession: NZ_AP022072 Location: 1..77891 Organism: Escherichia coli strain WP4-W18-ESBL-09 Replicon: plasmid pWP4-W18-ESBL-09_3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7R28_RS26375 () | 101..331 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| H7R28_RS26380 () | 383..661 | + | 279 | WP_182918142.1 | hypothetical protein | - |
| H7R28_RS26385 () | 843..2378 | + | 1536 | WP_000447015.1 | IS21 family transposase ISSso4 | Transposase |
| H7R28_RS26390 () | 2395..3150 | + | 756 | WP_001282653.1 | IS21 family transposase ISSso4 | Transposase |
| H7R28_RS26395 () | 3215..4390 | + | 1176 | WP_182918143.1 | DUF3560 domain-containing protein | - |
| H7R28_RS26400 () | 4437..5000 | + | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| H7R28_RS26405 () | 5086..5529 | - | 444 | WP_128472901.1 | hypothetical protein | - |
| H7R28_RS26410 () | 5831..6358 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| H7R28_RS26415 () | 6416..6649 | + | 234 | WP_033551487.1 | DUF905 family protein | - |
| H7R28_RS26420 () | 6710..8674 | + | 1965 | WP_001537566.1 | ParB/RepB/Spo0J family partition protein | - |
| H7R28_RS26425 () | 8743..9177 | + | 435 | WP_052983109.1 | conjugation system SOS inhibitor PsiB | - |
| H7R28_RS26430 () | 9174..9893 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 9905..10129 | + | 225 | NuclAT_0 | - | - |
| - () | 9905..10129 | + | 225 | NuclAT_0 | - | - |
| - () | 9905..10129 | + | 225 | NuclAT_0 | - | - |
| - () | 9905..10129 | + | 225 | NuclAT_0 | - | - |
| H7R28_RS26435 () | 9914..10093 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| H7R28_RS26440 () | 10173..10331 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H7R28_RS26445 () | 10632..10836 | - | 205 | Protein_14 | pilus protein | - |
| H7R28_RS26450 () | 11228..11524 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| H7R28_RS26455 () | 11635..12456 | + | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| H7R28_RS26460 () | 12753..13343 | - | 591 | WP_000252683.1 | hypothetical protein | VF |
| H7R28_RS26465 () | 13676..14059 | + | 384 | WP_001151529.1 | relaxosome protein TraM | - |
| H7R28_RS26470 () | 14251..14898 | + | 648 | WP_000332523.1 | transcriptional regulator TraJ family protein | - |
| H7R28_RS26475 () | 15006..15245 | + | 240 | WP_042018283.1 | conjugal transfer relaxosome protein TraY | - |
| H7R28_RS26480 () | 15279..15638 | + | 360 | WP_001098994.1 | type IV conjugative transfer system pilin TraA | - |
| H7R28_RS26485 () | 15653..15964 | + | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| H7R28_RS26490 () | 15986..16552 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| H7R28_RS26495 () | 16539..17267 | + | 729 | WP_001230769.1 | type-F conjugative transfer system secretin TraK | - |
| H7R28_RS26500 () | 17267..18694 | + | 1428 | WP_052983112.1 | conjugal transfer protein TraB | - |
| H7R28_RS26505 () | 18684..19274 | + | 591 | WP_000002784.1 | conjugal transfer protein TraP | - |
| H7R28_RS26510 () | 19213..19581 | + | 369 | WP_001681801.1 | conjugal transfer protein TrbD | - |
| H7R28_RS26515 () | 19578..20093 | + | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H7R28_RS26520 () | 20228..20449 | + | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| H7R28_RS26525 () | 20442..20855 | + | 414 | WP_000549589.1 | hypothetical protein | - |
| H7R28_RS26530 () | 20848..21321 | + | 474 | WP_033807958.1 | hypothetical protein | - |
| H7R28_RS26535 () | 21420..21638 | + | 219 | WP_052983091.1 | hypothetical protein | - |
| H7R28_RS26540 () | 21666..22013 | + | 348 | WP_000836682.1 | hypothetical protein | - |
| H7R28_RS26545 () | 22139..24769 | + | 2631 | WP_000069772.1 | type IV secretion system protein TraC | - |
| H7R28_RS26550 () | 24766..25152 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| H7R28_RS26555 () | 25149..25781 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| H7R28_RS26560 () | 25778..26770 | + | 993 | WP_000830849.1 | conjugal transfer pilus assembly protein TraU | - |
| H7R28_RS26565 () | 26797..27105 | + | 309 | WP_001617739.1 | hypothetical protein | - |
| H7R28_RS26570 () | 27274..27591 | + | 318 | Protein_39 | TraU family protein | - |
| H7R28_RS26575 () | 27621..27926 | + | 306 | WP_000224418.1 | hypothetical protein | - |
| H7R28_RS26580 () | 27935..28573 | + | 639 | WP_060578158.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H7R28_RS26585 () | 28570..30420 | + | 1851 | WP_088251385.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H7R28_RS26590 () | 30447..30704 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| H7R28_RS26595 () | 30697..31440 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H7R28_RS26600 () | 31454..31795 | + | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| H7R28_RS26605 () | 31776..32111 | - | 336 | WP_000736414.1 | hypothetical protein | - |
| H7R28_RS26610 () | 32192..32476 | + | 285 | WP_000624107.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H7R28_RS26615 () | 32463..33006 | + | 544 | Protein_48 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H7R28_RS26620 () | 32936..33283 | + | 348 | WP_071840683.1 | P-type conjugative transfer protein TrbJ | - |
| H7R28_RS26625 () | 33264..33655 | + | 392 | Protein_50 | F-type conjugal transfer protein TrbF | - |
| H7R28_RS26630 () | 33642..35012 | + | 1371 | Protein_51 | conjugal transfer protein TraH | - |
| H7R28_RS26635 () | 35009..37834 | + | 2826 | WP_182918144.1 | conjugal transfer mating pair stabilization protein TraG | - |
| H7R28_RS26640 () | 37831..38340 | + | 510 | WP_000628099.1 | conjugal transfer entry exclusion protein TraS | - |
| H7R28_RS26645 () | 38354..39085 | + | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| H7R28_RS26650 () | 39288..40025 | + | 738 | WP_000199905.1 | hypothetical protein | - |
| H7R28_RS26655 () | 40076..42283 | + | 2208 | WP_167790585.1 | type IV conjugative transfer system coupling protein TraD | - |
| H7R28_RS26660 () | 42283..47553 | + | 5271 | WP_182918141.1 | Multifunctional conjugation protein TraI | Relaxase |
| H7R28_RS26665 () | 47573..48319 | + | 747 | WP_088251383.1 | conjugal transfer pilus acetylase TraX | - |
| H7R28_RS26670 () | 48378..49238 | + | 861 | WP_000704524.1 | putative protein YcjY | VF |
| H7R28_RS26675 () | 49341..49901 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| H7R28_RS26680 () | 50030..50242 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| H7R28_RS26685 () | 50487..50948 | + | 462 | WP_016230918.1 | thermonuclease family protein | - |
| H7R28_RS26690 () | 50994..51203 | + | 210 | WP_001369435.1 | hemolysin expression modulator Hha | - |
| H7R28_RS26695 () | 51241..51831 | + | 591 | WP_042018152.1 | DUF2726 domain-containing protein | - |
| H7R28_RS26700 () | 51986..52459 | + | 474 | WP_016240489.1 | hypothetical protein | - |
| - () | 52602..52661 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 52602..52661 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 52602..52661 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 52602..52661 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| H7R28_RS26705 () | 52706..52855 | + | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H7R28_RS26710 () | 53140..53388 | + | 249 | WP_000083839.1 | replication regulatory protein RepA | - |
| H7R28_RS26715 () | 53633..53707 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| H7R28_RS26720 () | 53700..54557 | + | 858 | WP_016240488.1 | incFII family plasmid replication initiator RepA | - |
| H7R28_RS26725 () | 55472..55741 | + | 270 | WP_000079928.1 | hypothetical protein | Antitoxin Detail |
| H7R28_RS26730 () | 55738..56019 | + | 282 | WP_000970000.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| H7R28_RS26735 () | 56065..56913 | + | 849 | WP_032256585.1 | 3'-5' exonuclease | - |
| H7R28_RS26740 () | 57030..57512 | + | 483 | WP_001311056.1 | hypothetical protein | - |
| H7R28_RS26745 () | 57814..58161 | + | 348 | WP_088251382.1 | hypothetical protein | - |
| H7R28_RS26750 () | 58179..58769 | - | 591 | WP_032256264.1 | hypothetical protein | - |
| H7R28_RS26755 () | 58993..59178 | + | 186 | WP_032256266.1 | hypothetical protein | - |
| H7R28_RS26760 () | 59241..60110 | - | 870 | WP_032256267.1 | hypothetical protein | - |
| H7R28_RS26765 () | 60658..60876 | + | 219 | WP_032256270.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| H7R28_RS26770 () | 60878..61183 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| H7R28_RS26775 () | 61505..62639 | - | 1135 | Protein_80 | IS91 family transposase IS91 | Transposase |
| H7R28_RS26780 () | 62602..63003 | - | 402 | WP_050488175.1 | hypothetical protein | - |
| H7R28_RS26785 () | 63531..64040 | + | 510 | WP_000115001.1 | peptide deformylase | - |
| H7R28_RS26790 () | 64055..64156 | + | 102 | Protein_83 | methionyl-tRNA formyltransferase | - |
| H7R28_RS26795 () | 64416..64544 | + | 129 | Protein_84 | DUF2164 family protein | - |
| H7R28_RS26800 () | 64541..64903 | + | 363 | WP_000181069.1 | hypothetical protein | - |
| H7R28_RS26805 () | 65236..65763 | - | 528 | WP_001196880.1 | DoxX family protein | - |
| H7R28_RS26810 () | 65765..66523 | - | 759 | WP_001181584.1 | DNA-binding domain-containing protein | - |
| H7R28_RS26815 () | 66492..67418 | - | 927 | WP_000989040.1 | DUF692 domain-containing protein | - |
| H7R28_RS26820 () | 67450..67740 | - | 291 | WP_000754126.1 | DUF2282 domain-containing protein | - |
| H7R28_RS26825 () | 68049..68606 | - | 558 | WP_000103553.1 | hypothetical protein | VF |
| H7R28_RS26830 () | 69255..69821 | + | 567 | WP_000587874.1 | hypothetical protein | - |
| H7R28_RS26835 () | 69889..70008 | - | 120 | Protein_92 | transposase domain-containing protein | - |
| H7R28_RS26840 () | 70211..71191 | + | 981 | WP_001218105.1 | plasmid segregation protein ParM | - |
| H7R28_RS26845 () | 71194..71616 | + | 423 | WP_000774834.1 | plasmid partitioning/stability family protein | - |
| H7R28_RS26850 () | 72040..72942 | + | 903 | WP_088251389.1 | DUF1281 domain-containing protein | - |
| H7R28_RS26855 () | 72939..73250 | + | 312 | WP_012680995.1 | hypothetical protein | - |
| H7R28_RS26860 () | 73326..74009 | + | 684 | WP_023485601.1 | DNA methylase | - |
| H7R28_RS26865 () | 74010..74231 | + | 222 | WP_001104892.1 | hypothetical protein | - |
| H7R28_RS26870 () | 74245..74679 | + | 435 | WP_001415415.1 | DUF1380 family protein | - |
| H7R28_RS26875 () | 74723..75493 | + | 771 | WP_088251381.1 | hypothetical protein | - |
| H7R28_RS26880 () | 76031..76333 | + | 303 | WP_072105978.1 | antirestriction protein | - |
| H7R28_RS26885 () | 76380..76802 | + | 423 | WP_000271727.1 | DUF1380 family protein | - |
| H7R28_RS26890 () | 76799..76990 | + | 192 | WP_001024838.1 | hypothetical protein | - |
| H7R28_RS26895 () | 76969..77475 | - | 507 | Protein_104 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|