T4SS ID367
StrainBrucella microti CCM 4915
Repliconchromosome 2 [Browse all T4SS(s) in this replicon]
Functioneffector translocation
ClassificationType IVA; Type P
experimental Experimental investigation has been performed on this T4SS.

T4SS components

The information of T4SS components from NC_013118
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1BMI_II5853150..54553 [-], 1404256014852amino acid permease family protein 
2BMI_II5954771..55922 [-], 1152256014853hypothetical protein 
3BMI_II6056173..56691 [-], 519256014854lipoprotein 
4BMI_II61 (virB11)56837..57931 [-], 1095256014855type IV secretion system protein VirB11  VirB11
5BMI_II62 (virB10)57906..59081 [-], 1176256014856type IV secretion system protein VirB10  VirB10
6BMI_II63 (virB9)59078..59947 [-], 870256014857type IV secretion system protein VirB9  VirB9
7BMI_II64 (virB8)59944..60663 [-], 720256014858type IV secretion system protein VirB8  VirB8
8BMI_II65 (virB7)60666..60839 [-], 174256014859type IV secretion system protein VirB7  VirB7
9BMI_II66 (virB6)61003..62046 [-], 1044256014860type IV secretion system protein VirB6  VirB6
10BMI_II67 (virB5)62230..62946 [-], 717256014861type IV secretion system protein VirB5  VirB5
11BMI_II68 (virB4)62951..65446 [-], 2496256014862type IV secretion system protein VirB4  VirB4
12BMI_II69 (virB3)65446..65796 [-], 351256014863type IV secretion system protein VirB3  VirB3
13BMI_II70 (virB2)65810..66127 [-], 318256014864type IV secretion system protein VirB2  VirB2
14BMI_II71 (virB1)66563..67279 [-], 717256014865type IV secretion system protein VirB1  VirB1
15BMI_II7267783..69021 [-], 1239256014866membrane-bound lytic murein transglycosylase B 
16BMI_II73 (galU)69433..70326 [+], 894256014867UTP--glucose-1-phosphate uridylyltransferase 
17BMI_II7470379..71917 [-], 1539256014868hypothetical protein 
flank Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

Download FASTA format files
Proteins        Genes

BPE123, BPE043, VceC, BPE275, RicA, VceA, BPE005

The information of protein effectors
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  *
1BMI_II124 122219..122680 [-], 462256014914hypothetical protein  BPE123
2BMI_I1027 992956..997692 [-], 4737256369448hypothetical protein  BPE043
3BMI_I1041 1006731..1007987 [-], 1257256369462Basic proline-rich protein precursor  VceC
4BMI_I1268 1228421..1229182 [-], 762256369678rhomboid family protein  BPE275
5BMI_I1271 1231110..1231637 [-], 528256369681ferripyochelin-binding protein, putative  RicA
6BMI_I1652 1590170..1590487 [+], 318256370049hypothetical protein  VceA
7BMI_I2027 1936797..1937258 [-], 462256370405cyclic nucleotide-binding protein  BPE005

Download FASTA format files
Proteins        Genes
(1) de Jong MF; Tsolis RM (2012). Brucellosis and type IV secretion. Future Microbiol. 7(1):47-58. [PudMed:22191446]
(2) Hanna N; Jimenez de Bagues MP; Ouahrani-Bettache S; El Yakhlifi Z; Kohler S; Occhialini A (2011). The virB operon is essential for lethality of Brucella microti in the Balb/c murine model of infection. J Infect Dis. 203(8):1129-35. [PudMed:21451001] experimental
experimental This literature contains experimental investigation