 T4SS ID | 367 |
| Strain | Brucella microti CCM 4915 |
| Replicon | chromosome 2 [Browse all T4SS(s) in this replicon] |
| Accession | NC_013118 |
| Location | 56837..67279 |
| Name | VirB |
| Function | effector translocation |
| Classification | Type IVA; Type P |
 Experimental investigation has been performed on this T4SS. | |
T4SS components |
| Component | VirB1 | VirB2 | VirB3 | VirB4 | VirB5 | VirB6 | VirB7 | VirB8 | VirB9 |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component | VirB10 | VirB11 | VirD4 | ||||||
| Number | 1 | 1 | 0 |
The information of T4SS components from NC_013118 | ||||||
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| # | Locus tag (Gene) | Coordinates [+/-], size (bp) | Protein GI | Product | Component | |
| 1 | BMI_II58 | 53150..54553 [-], 1404 | 256014852 | amino acid permease family protein | ||
| 2 | BMI_II59 | 54771..55922 [-], 1152 | 256014853 | hypothetical protein | ||
| 3 | BMI_II60 | 56173..56691 [-], 519 | 256014854 | lipoprotein | ||
| 4 | BMI_II61 (virB11) | 56837..57931 [-], 1095 | 256014855 | type IV secretion system protein VirB11 | VirB11 | |
| 5 | BMI_II62 (virB10) | 57906..59081 [-], 1176 | 256014856 | type IV secretion system protein VirB10 | VirB10 | |
| 6 | BMI_II63 (virB9) | 59078..59947 [-], 870 | 256014857 | type IV secretion system protein VirB9 | VirB9 | |
| 7 | BMI_II64 (virB8) | 59944..60663 [-], 720 | 256014858 | type IV secretion system protein VirB8 | VirB8 | |
| 8 | BMI_II65 (virB7) | 60666..60839 [-], 174 | 256014859 | type IV secretion system protein VirB7 | VirB7 | |
| 9 | BMI_II66 (virB6) | 61003..62046 [-], 1044 | 256014860 | type IV secretion system protein VirB6 | VirB6 | |
| 10 | BMI_II67 (virB5) | 62230..62946 [-], 717 | 256014861 | type IV secretion system protein VirB5 | VirB5 | |
| 11 | BMI_II68 (virB4) | 62951..65446 [-], 2496 | 256014862 | type IV secretion system protein VirB4 | VirB4 | |
| 12 | BMI_II69 (virB3) | 65446..65796 [-], 351 | 256014863 | type IV secretion system protein VirB3 | VirB3 | |
| 13 | BMI_II70 (virB2) | 65810..66127 [-], 318 | 256014864 | type IV secretion system protein VirB2 | VirB2 | |
| 14 | BMI_II71 (virB1) | 66563..67279 [-], 717 | 256014865 | type IV secretion system protein VirB1 | VirB1 | |
| 15 | BMI_II72 | 67783..69021 [-], 1239 | 256014866 | membrane-bound lytic murein transglycosylase B | ||
| 16 | BMI_II73 (galU) | 69433..70326 [+], 894 | 256014867 | UTP--glucose-1-phosphate uridylyltransferase | ||
| 17 | BMI_II74 | 70379..71917 [-], 1539 | 256014868 | hypothetical protein | ||
 Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any. |
Download FASTA format files |
| Proteins Genes |
Effectors |
| BPE123, BPE043, VceC, BPE275, RicA, VceA, BPE005 |
The information of protein effectors | ||||||
| # | Locus tag (Gene) | Coordinates [+/-], size (bp) | Protein GI | Product | * | |
| 1 | BMI_II124 | 122219..122680 [-], 462 | 256014914 | hypothetical protein | BPE123 | |
| 2 | BMI_I1027 | 992956..997692 [-], 4737 | 256369448 | hypothetical protein | BPE043 | |
| 3 | BMI_I1041 | 1006731..1007987 [-], 1257 | 256369462 | Basic proline-rich protein precursor | VceC | |
| 4 | BMI_I1268 | 1228421..1229182 [-], 762 | 256369678 | rhomboid family protein | BPE275 | |
| 5 | BMI_I1271 | 1231110..1231637 [-], 528 | 256369681 | ferripyochelin-binding protein, putative | RicA | |
| 6 | BMI_I1652 | 1590170..1590487 [+], 318 | 256370049 | hypothetical protein | VceA | |
| 7 | BMI_I2027 | 1936797..1937258 [-], 462 | 256370405 | cyclic nucleotide-binding protein | BPE005 | |
Download FASTA format files |
| Proteins Genes |
| (1) de Jong MF; Tsolis RM (2012). Brucellosis and type IV secretion. Future Microbiol. 7(1):47-58. [PudMed:22191446] |
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(2) Hanna N; Jimenez de Bagues MP; Ouahrani-Bettache S; El Yakhlifi Z; Kohler S; Occhialini A (2011). The virB operon is essential for lethality of Brucella microti in the Balb/c murine model of infection. J Infect Dis. 203(8):1129-35. [PudMed:21451001]
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| This literature contains experimental investigation |