 T4SS ID | 227 |
| Strain | Bartonella grahamii as4aup |
| Replicon | chromosome [Browse all T4SS(s) in this replicon] |
| Accession | NC_012846 |
| Location | 1670135..1682889 |
| Name | VirB |
| Function | effector translocation |
| Classification | Type IVA; Type P |
 This T4SS has been mentioned in a genome sequencing report. | |
Information of structure: 
T4SS components |
| Component | VirB1 | VirB2 | VirB3 | VirB4 | VirB5 | VirB6 | VirB7 | VirB8 | VirB9 |
| Number | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component | VirB10 | VirB11 | VirD4 | ||||||
| Number | 1 | 1 | 1 |
The information of T4SS components from NC_012846 | ||||||
 | ||||||
| # | Locus tag (Gene) | Coordinates [+/-], size (bp) | Protein GI | Product | Component | |
| 1 | Bgr_14780 | 1667008..1667367 [+], 360 | 240850955 | transcriptional regulator | ||
| 2 | Bgr_14800 | 1668998..1669693 [-], 696 | 240850956 | hypothetical protein | ||
| 3 | Bgr_14810 (virB2) | 1670135..1670461 [+], 327 | 240850957 | VirB2 protein | VirB2 | |
| 4 | Bgr_14820 (virB3) | 1670462..1670770 [+], 309 | 240850958 | VirB3 protein | VirB3 | |
| 5 | Bgr_14830 (virB4) | 1670793..1673147 [+], 2355 | 240850959 | VirB4 protein | VirB4 | |
| 6 | Bgr_14840 (virB5) | 1673144..1673665 [+], 522 | 240850960 | VirB5 protein | VirB5 | |
| 7 | Bgr_14850 (virB6) | 1673652..1674638 [+], 987 | 240850961 | VirB6 protein | VirB6 | |
| 8 | Bgr_14860 (virB7) | 1674849..1675151 [+], 303 | 240850962 | VirB7 protein | VirB7 | |
| 9 | Bgr_14870 (virB8) | 1675141..1675809 [+], 669 | 240850963 | VirB8 protein | VirB8 | |
| 10 | Bgr_14880 (virB9) | 1675806..1676672 [+], 867 | 240850964 | VirB9 protein | VirB9 | |
| 11 | Bgr_14890 (virB10) | 1676665..1677825 [+], 1161 | 240850965 | VirB10 protein | VirB10 | |
| 12 | Bgr_14900 (virB11) | 1677822..1678892 [+], 1071 | 240850966 | VirB11 protein | VirB11 | |
| 13 | Bgr_14910 | 1678958..1679173 [+], 216 | 240850967 | hypothetical protein | ||
| 14 | Bgr_14920 (bepA) | 1679184..1680818 [+], 1635 | 240850968 | BepA protein | ||
| 15 | Bgr_14930 (traG1) | 1680973..1682889 [+], 1917 | 240850969 | conjugal transfer coupling protein TraG | VirD4 | |
| 16 | Bgr_14940 | 1683893..1684093 [+], 201 | 240850970 | hypothetical protein | ||
| 17 | Bgr_14950 (bepC) | 1684104..1685702 [+], 1599 | 240850971 | BepC protein | ||
| 18 | Bgr_14960 (bepD) | 1686016..1687185 [+], 1170 | 240850972 | BepD protein | ||
 Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any. |
Download FASTA format files |
| Proteins Genes |
Effectors |
| BepA, BepC, BepD, BepH, BepE, BepF, BepI |
The information of protein effectors | ||||||
| # | Locus tag (Gene) | Coordinates [+/-], size (bp) | Protein GI | Product | * | |
| 1 | Bgr_14920 (bepA) | 1679184..1680818 [+], 1635 | 240850968 | BepA protein | BepA | |
| 2 | Bgr_14950 (bepC) | 1684104..1685702 [+], 1599 | 240850971 | BepC protein | BepC | |
| 3 | Bgr_14960 (bepD) | 1686016..1687185 [+], 1170 | 240850972 | BepD protein | BepD | |
| 4 | Bgr_14970 (bepH) | 1687510..1688340 [+], 831 | 240850973 | BepH protein | BepH | |
| 5 | Bgr_14980 (bepE) | 1688666..1689946 [+], 1281 | 240850974 | BepE protein | BepE | |
| 6 | Bgr_14990 (bepF) | 1690157..1691983 [+], 1827 | 240850975 | BepF protein | BepF | |
| 7 | Bgr_15000 (bepI) | 1692301..1695510 [+], 3210 | 240850976 | BepI protein | BepI | |
Download FASTA format files |
| Proteins Genes |
| # | Name | Image | Resource | Detail | Reference |
| 1 | VirB8 |  | PDB (4KZ1) | Crystal structure of the soluble domain of VirB8 from Bartonella grahamii. | (1) PubMed: 26646013 |
(1) Gillespie JJ et al. (2015). Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems. MBio. 6(6):e01867-15. [PudMed:26646013] 
|
| (1) Berglund EC; Frank AC; Calteau A; Vinnere Pettersson O; Granberg F; Eriksson AS; Naslund K; Holmberg M; Lindroos H; Andersson SG (2009). Run-off replication of host-adaptability genes is associated with gene transfer agents in the genome of mouse-infecting Bartonella grahamii. PLoS Genet. 5(7):e1000546. [PudMed:19578403] |