SecReT4
T4SS ID227
StrainBartonella grahamii as4aup
Repliconchromosome [Browse all T4SS(s) in this replicon]
AccessionNC_012846
Location1670135..1682889
NameVirB
Functioneffector translocation
ClassificationType IVA; Type P
sequence This T4SS has been mentioned in a genome sequencing report.
structure Information of structure: structureVirB8

T4SS components
ComponentVirB1VirB2VirB3VirB4VirB5VirB6VirB7VirB8VirB9
Number011111111
ComponentVirB10VirB11VirD4
Number111

The information of T4SS components from NC_012846
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1Bgr_147801667008..1667367 [+], 360240850955transcriptional regulator 
2Bgr_148001668998..1669693 [-], 696240850956hypothetical protein 
3Bgr_14810 (virB2)1670135..1670461 [+], 327240850957VirB2 protein  VirB2
4Bgr_14820 (virB3)1670462..1670770 [+], 309240850958VirB3 protein  VirB3
5Bgr_14830 (virB4)1670793..1673147 [+], 2355240850959VirB4 protein  VirB4
6Bgr_14840 (virB5)1673144..1673665 [+], 522240850960VirB5 protein  VirB5
7Bgr_14850 (virB6)1673652..1674638 [+], 987240850961VirB6 protein  VirB6
8Bgr_14860 (virB7)1674849..1675151 [+], 303240850962VirB7 protein  VirB7
9Bgr_14870 (virB8)1675141..1675809 [+], 669240850963VirB8 protein  VirB8
10Bgr_14880 (virB9)1675806..1676672 [+], 867240850964VirB9 protein  VirB9
11Bgr_14890 (virB10)1676665..1677825 [+], 1161240850965VirB10 protein  VirB10
12Bgr_14900 (virB11)1677822..1678892 [+], 1071240850966VirB11 protein  VirB11
13Bgr_149101678958..1679173 [+], 216240850967hypothetical protein 
14Bgr_14920 (bepA)1679184..1680818 [+], 1635240850968BepA protein 
15Bgr_14930 (traG1)1680973..1682889 [+], 1917240850969conjugal transfer coupling protein TraG  VirD4
16Bgr_149401683893..1684093 [+], 201240850970hypothetical protein 
17Bgr_14950 (bepC)1684104..1685702 [+], 1599240850971BepC protein 
18Bgr_14960 (bepD)1686016..1687185 [+], 1170240850972BepD protein 
 
flank Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

Download FASTA format files
Proteins        Genes

Effectors
BepA, BepC, BepD, BepH, BepE, BepF, BepI

The information of protein effectors
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  *
1Bgr_14920 (bepA)1679184..1680818 [+], 1635240850968BepA protein  BepA
2Bgr_14950 (bepC)1684104..1685702 [+], 1599240850971BepC protein  BepC
3Bgr_14960 (bepD)1686016..1687185 [+], 1170240850972BepD protein  BepD
4Bgr_14970 (bepH)1687510..1688340 [+], 831240850973BepH protein  BepH
5Bgr_14980 (bepE)1688666..1689946 [+], 1281240850974BepE protein  BepE
6Bgr_14990 (bepF)1690157..1691983 [+], 1827240850975BepF protein  BepF
7Bgr_15000 (bepI)1692301..1695510 [+], 3210240850976BepI protein  BepI


Download FASTA format files
Proteins        Genes
The information on structure of this T4ss

#NameImageResourceDetailReference
1VirB84KZ1 PDB (4KZ1)Crystal structure of the soluble domain of VirB8 from Bartonella grahamii.(1) PubMed: 26646013
(1) Gillespie JJ et al. (2015). Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems. MBio. 6(6):e01867-15. [PudMed:26646013] experimental
(1) Berglund EC; Frank AC; Calteau A; Vinnere Pettersson O; Granberg F; Eriksson AS; Naslund K; Holmberg M; Lindroos H; Andersson SG (2009). Run-off replication of host-adaptability genes is associated with gene transfer agents in the genome of mouse-infecting Bartonella grahamii. PLoS Genet. 5(7):e1000546. [PudMed:19578403]