| Effector Protein ID: 240850968 |
 T4SS name [ID] | VirB [227] |
| Gene symbol | bepA |
| Locus tag | Bgr_14920 |
| Strain | Bartonella grahamii as4aup |
| Replicon | chromosome [GenBank: NC_012846] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1679184..1680818 [+] |
| Product | BepA protein |
| Effector type | Protein |
| Descripton | BepA |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Predicted effector. Homologous to BepA. The Bartonella-translocated effector protein (BepA-BepG) are required for invasion, proinflammatory activation and antiapoptotic protection of endothelial cells. |
| UniProt ID | C6AES4 |
| KEGG ID | bgr:Bgr_14920 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Fic [PF02661], Evalue: 1.7e-13, Aligned region: 63..176 |
| Protein Sequence: 544 a.a. [Download] |
| >gi|240850968|ref|YP_002972368.1| BepA protein [Bartonella grahamii as4aup] MPKAKEKTKNIQTVSPHHYVYPNTTTLKNKYGIKNFKSFLEKCSHDTAKAMVNLREAPLPEKFDTSYLCS IHYQLFKNTFEWAGHLRHLPFTFEDGTTAAMPEMKRTGWENPFALGDEIPKGLQKLDQTLAEKDNLQGLT RETFNSEAISLFNFLNQLDPFREGNGRTQRVFFEKLAQAAGHQLDFSLVTKERMMLASVAVAENGDLEPM QHLFEDISNPNKILLLKEFMNNMKELGRNVNDRPVMVAKEGETYTGMYRGAGYDSFAFNVKGAYIIGNKE HLTPEQLKTLKPGDKFTFTVPKTKELESILIPEERLAPLTENKKAEMVAEDSCVHASLKQVQKLAKIVYG KEKTLDKQMLEIIKNPSLGQQLANQIERAPHSVSHLAGFSLCGLQNQARANAKNHLEMLCTAVANFTHAV KHAEKEITQEHATEQSRRAKIVKIPSKSLQELFTLPKELQQEALAKNPLLQKELTDFVKNINSRLSLTEH KAVKNNEYETLAQSIGVSENKAKQITQTVKQAKELHQQTQVCTMHRSKAFAMAC |
| - |
| Nucleotide Sequence: 1635 bp [Download] |
| >gi|240849682|ref|NC_012846.1|:1679184-1680818 Bartonella grahamii as4aup, complete genome ATGCCAAAAGCAAAAGAAAAAACAAAAAATATACAGACAGTTTCTCCCCATCATTATGTCTACCCGAACA CCACAACACTCAAAAATAAATATGGAATAAAAAACTTTAAATCCTTTCTGGAGAAATGCTCGCATGATAC AGCAAAAGCGATGGTTAATCTGCGTGAAGCCCCCCTACCAGAAAAATTTGATACCTCCTATCTATGCTCT ATTCATTATCAGTTATTTAAAAATACCTTTGAATGGGCTGGTCATCTTCGCCATCTTCCCTTTACATTTG AAGATGGTACCACAGCCGCTATGCCCGAAATGAAAAGAACAGGATGGGAAAATCCTTTTGCACTCGGTGA TGAAATCCCTAAAGGTTTACAAAAATTAGATCAAACACTTGCCGAAAAAGATAATTTGCAAGGCCTAACG CGTGAGACATTTAACTCTGAAGCAATAAGTTTATTTAACTTCCTTAACCAACTCGATCCTTTTAGAGAAG GCAACGGACGTACACAACGAGTCTTTTTTGAAAAGCTCGCTCAAGCAGCAGGCCATCAGCTTGATTTTTC ACTTGTTACAAAAGAACGCATGATGCTCGCCAGTGTTGCTGTAGCAGAAAATGGTGATCTAGAACCAATG CAACATCTATTTGAGGATATCTCTAATCCCAATAAAATACTTCTTTTAAAGGAATTCATGAACAACATGA AAGAACTTGGGCGCAATGTTAATGATCGTCCCGTTATGGTTGCAAAAGAAGGTGAAACATACACAGGAAT GTATAGAGGTGCTGGTTATGATAGCTTTGCATTCAATGTGAAAGGGGCTTATATCATCGGCAATAAAGAG CATCTCACACCAGAACAACTCAAAACATTAAAACCCGGTGACAAATTTACCTTTACAGTTCCAAAAACAA AAGAGCTTGAAAGCATTCTCATTCCAGAAGAAAGATTAGCTCCTTTGACAGAAAATAAAAAAGCCGAAAT GGTTGCAGAAGATTCTTGCGTCCACGCAAGCTTAAAACAGGTCCAGAAATTGGCAAAAATTGTTTATGGT AAAGAAAAAACATTAGATAAACAGATGCTAGAGATCATCAAAAATCCAAGCTTAGGCCAACAGCTCGCCA ACCAGATTGAAAGAGCACCGCACTCTGTTTCTCATCTTGCAGGTTTCAGTTTATGCGGACTACAAAATCA AGCACGTGCAAACGCTAAAAATCATCTTGAGATGCTCTGTACTGCCGTTGCAAATTTCACCCATGCTGTA AAACATGCGGAGAAGGAAATTACTCAAGAACATGCAACAGAACAAAGTCGTCGTGCAAAAATAGTAAAAA TACCAAGCAAAAGCTTACAAGAGCTCTTCACCTTGCCAAAAGAATTACAGCAAGAAGCTTTAGCAAAAAA TCCTTTACTTCAAAAAGAGCTTACCGACTTTGTAAAAAACATCAATAGCCGTCTCTCACTAACTGAACAT AAAGCTGTCAAAAATAATGAGTATGAAACACTGGCTCAAAGCATTGGTGTATCAGAAAATAAAGCCAAAC AAATTACACAAACCGTTAAGCAAGCCAAAGAGCTACATCAGCAAACACAAGTATGCACAATGCATCGTTC CAAAGCATTTGCTATGGCTTGCTAA |
| Reference |
(1) Paziewska A; Sinski E; Harris PD (2012). Recombination, Diversity and Allele Sharing of Infectivity Proteins Between Bartonella Species from Rodents. Microb Ecol. . [PudMed:22419104] 
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| experimental literature |