SecReT4
Effector Protein ID: 240850976
T4SS name [ID]VirB [227]
Gene symbolbepI
Locus tagBgr_15000
StrainBartonella grahamii as4aup
Repliconchromosome [GenBank: NC_012846] [Browse all T4SS(s) in this replicon]
Location [Strand]1692301..1695510 [+]
ProductBepI protein
Effector typeProtein
DescriptonBepI
T4CP requirementT4CP Depedent
Target/EffectionPredicted effector. Homologous to BepA protein BepC protein and BepG protein. The Bartonella-translocated effector protein (BepA-BepG) are required for invasion, proinflammatory activation and antiapoptotic protection of endothelial cells.
UniProt IDC6AET2
KEGG IDbgr:Bgr_15000
PDB IDNA
Domain hit(s) vs Pfam Fic [PF02661], Evalue: 6.5e-32, Aligned region: 82..194
Fic [PF02661], Evalue: 6.5e-32, Aligned region: 531..641
Protein Sequence: 1069 a.a.     [Download]
>gi|240850976|ref|YP_002972376.1| BepI protein [Bartonella grahamii as4aup]
MKENTKHYASSTQEELQEQHPAISAAISKQINKASQNFFYPNSKLLKNKYRIKEQEILKEQCCDDVKKEM
IKLRQEPLPEQFNSSYLKYLHQRLFSRAFEWAGQTREEPFTFEDGTVASMPILKRKEFTKPFAIGRKIQE
GLEKLDKTLAEKNNLQGLTREEFVEQAAGIMIDLHHMHPFREGNRRTKRLFVEKLAQAAGHELDFSLVSK
KRKDFVRAAAMEHSNPEPMKHLLEDISNPEKLLILQEFINSMRELGLDEKNYYLAVVAKEGETYHGTYRG
SGPNGFMLDANGIFILGNKKDLTPEQIQTLKIGDALSFTAPKTQNPEKNQQKTFLPEKKRAALTNDEITK
KSKDNASIQTKKKEKAHFSPWIAPHALHDSIEVMSQSLQEQMTNPIAQSASSMRQMQKDFQKNTLQTSNT
ATNNPISVQMTKEKRSDHQERTKQPPKKAMAYWDTGTKKMDTVPLILQEKLSSSPETEENKTMYRNFFCP
NSITLKNKYGINDYKKLKVQCAHDTTKAIIHLRQEAPPQKLTSTYLQYIHHTLFKNTFEWAGQTREKPFT
FEDGTVAYMPMMKKAGISFASAKQIQEGLENLDKILSETNSLKGLTRETFVEYVTEMLIQLNYTHPFREG
NGRTQRMFFEKLGQVAGHTLDFSLATEKRMNLASISSLKHNDKEEMKHLLEDISNPEKILILKEFIDNMK
HIGFENIHHHLIITAKEGHTYKGFYRGSGPNGFMLDANGIFILGNKKDLTPEQIQTLKIGDALSFTAPKV
QNQQEVLIPAETIAPLTNNEIATKIKNNASIQARRKEIETLCQIIYGNRHILQERIEMIHENHTEGEQLT
YQIATSPQSISKLSGSNVFGIKNNARAHAEANILPLCRAIDRYINIFKQTERDILHTHHIKQRRCEQSVK
IPEAWMKNLFSLSKAQQQEILSNSPELRGEIRTYIKKINERLSSSEHEAIKENNPEKLAKCLGTSTVKAK
EIMEIVKQIKEIEQHIQPMYFYNHKFDECLAPNQHQPTKTNNKKKRSNTLDKEAIKVQKMKENVNQSSKR
QENIQPHKTEHAKAMTMNI
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Nucleotide Sequence: 3210 bp     [Download]
>gi|240849682|ref|NC_012846.1|:1692301-1695510 Bartonella grahamii as4aup, complete genome
ATGAAAGAAAACACTAAACATTATGCCTCTTCCACACAGGAAGAATTGCAAGAACAACACCCTGCAATTA
GTGCAGCCATTTCTAAACAAATCAATAAAGCATCGCAGAATTTCTTTTATCCCAATAGCAAACTGCTTAA
AAATAAATACCGCATCAAAGAGCAAGAAATATTAAAGGAACAATGTTGTGATGATGTAAAAAAAGAAATG
ATAAAACTGCGTCAAGAACCTCTACCAGAACAGTTTAATTCCTCCTATCTAAAATATCTTCATCAACGCC
TCTTTTCCCGTGCATTTGAATGGGCCGGACAAACACGCGAAGAGCCTTTTACATTTGAAGATGGTACTGT
TGCTTCTATGCCCATTTTGAAAAGAAAAGAATTTACAAAACCTTTTGCGATTGGCAGAAAAATACAGGAG
GGACTAGAAAAGTTAGATAAAACACTTGCTGAAAAGAATAATTTACAAGGCTTAACTCGCGAAGAATTCG
TTGAACAAGCAGCTGGAATAATGATAGATTTGCACCACATGCATCCTTTCAGAGAGGGCAATAGGCGCAC
AAAGAGACTGTTTGTTGAAAAACTCGCTCAAGCAGCAGGACATGAGCTAGACTTTTCTCTTGTGAGCAAA
AAACGTAAAGACTTTGTCCGCGCCGCTGCCATGGAACATAGCAATCCAGAGCCTATGAAGCATCTGCTTG
AGGATATCTCAAATCCAGAAAAATTGCTCATTTTACAAGAATTTATCAACTCTATGAGAGAACTTGGATT
GGATGAAAAAAATTATTATCTCGCTGTCGTCGCAAAAGAAGGAGAAACCTATCATGGTACCTACAGAGGC
AGTGGACCCAATGGCTTCATGCTTGATGCCAACGGGATTTTCATCTTGGGAAATAAAAAAGATCTCACCC
CAGAGCAAATACAGACATTAAAAATCGGTGACGCCCTCTCCTTTACAGCGCCCAAAACTCAAAACCCAGA
AAAAAACCAGCAAAAAACATTTCTTCCAGAAAAAAAAAGAGCCGCTCTCACAAACGATGAAATAACTAAA
AAGAGCAAAGACAACGCATCCATTCAAACAAAGAAAAAAGAAAAAGCCCATTTTTCACCATGGATTGCCC
CTCATGCTTTACATGACAGCATTGAAGTTATGTCCCAAAGTTTGCAAGAACAAATGACCAACCCAATTGC
TCAATCTGCTTCCTCCATGAGGCAAATGCAAAAAGATTTCCAAAAAAACACTTTACAGACCAGCAATACA
GCGACAAATAATCCAATATCTGTCCAAATGACAAAGGAAAAACGCTCTGATCATCAAGAAAGAACAAAAC
AGCCCCCAAAAAAAGCAATGGCATACTGGGACACTGGTACAAAAAAAATGGACACCGTCCCTCTCATCTT
ACAGGAGAAATTATCCTCATCGCCTGAAACTGAAGAAAATAAGACAATGTACCGTAATTTCTTTTGCCCT
AATAGTATCACCTTAAAAAATAAATATGGAATAAACGACTATAAAAAATTAAAAGTGCAATGTGCCCATG
ATACAACAAAAGCAATCATTCATCTACGCCAAGAAGCGCCACCGCAAAAATTAACTTCCACATATCTCCA
ATATATTCATCACACCCTATTTAAAAATACTTTTGAATGGGCCGGACAAACACGCGAAAAACCATTTACA
TTTGAAGATGGTACCGTTGCTTATATGCCAATGATGAAAAAAGCTGGGATTTCTTTTGCCTCAGCAAAAC
AGATACAAGAGGGACTAGAAAATTTAGATAAAATACTTTCTGAAACGAATAGTTTAAAAGGCTTAACCCG
CGAAACATTTGTTGAATATGTCACTGAAATGTTGATACAGCTCAACTATACGCATCCCTTCAGAGAAGGT
AATGGACGCACACAACGAATGTTTTTTGAAAAACTTGGGCAAGTTGCTGGTCACACACTCGACTTTTCTC
TTGCAACAGAAAAACGCATGAATCTTGCTAGCATTTCATCGCTAAAACACAACGATAAGGAAGAGATGAA
ACATCTTCTTGAGGATATCTCAAATCCAGAAAAAATACTTATTTTAAAAGAATTCATAGACAATATGAAA
CATATTGGATTTGAAAATATTCATCATCATCTTATTATAACAGCGAAAGAAGGGCATACCTATAAAGGTT
TCTACAGAGGTAGTGGACCCAATGGCTTCATGCTTGATGCCAACGGGATTTTCATCTTAGGAAATAAAAA
AGATCTCACCCCAGAGCAAATACAGACATTAAAAATCGGTGACGCCCTCTCCTTTACAGCACCAAAAGTT
CAAAACCAGCAAGAAGTGCTTATCCCCGCAGAAACAATAGCCCCCCTTACCAACAATGAAATTGCCACAA
AGATAAAAAACAATGCATCCATTCAAGCAAGAAGAAAAGAAATCGAAACTTTGTGCCAAATCATTTATGG
CAATCGTCATATTTTGCAGGAAAGAATAGAGATGATCCATGAAAATCATACTGAAGGAGAACAGCTCACC
TATCAAATTGCCACCTCTCCTCAATCTATTTCTAAGCTTTCTGGTAGCAATGTATTTGGCATAAAAAACA
ACGCGCGCGCCCATGCTGAAGCAAATATTTTGCCCCTCTGTAGAGCCATTGATCGTTATATCAATATTTT
TAAACAAACAGAAAGAGACATTCTCCATACCCATCATATAAAACAAAGGCGGTGTGAACAGTCGGTAAAA
ATTCCTGAGGCTTGGATGAAAAATCTCTTTTCCTTGTCAAAAGCACAACAGCAAGAAATTTTATCAAACT
CTCCTGAATTAAGGGGGGAGATAAGAACTTATATCAAAAAAATCAATGAGCGCTTATCCTCAAGCGAGCA
TGAAGCTATAAAGGAAAATAATCCTGAAAAACTTGCGAAGTGTCTTGGCACATCAACCGTTAAAGCAAAA
GAAATTATGGAAATAGTCAAGCAGATAAAAGAGATAGAACAGCATATACAACCCATGTATTTTTATAACC
ATAAATTCGATGAGTGCTTAGCACCAAACCAGCATCAACCTACAAAGACAAACAATAAAAAAAAACGTTC
CAACACTCTTGATAAAGAAGCAATTAAAGTGCAAAAAATGAAAGAAAACGTCAATCAGAGCTCTAAAAGA
CAAGAAAATATTCAACCTCACAAAACAGAGCACGCAAAAGCCATGACAATGAATATCTAA