Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   EL078_RS08925 Genome accession   NZ_LR134282
Coordinates   1794783..1796726 (-) Length   647 a.a.
NCBI ID   WP_027968297.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8140     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1789783..1801726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL078_RS08905 (NCTC8140_01807) cinA 1790904..1792163 (-) 1260 WP_074483864.1 competence/damage-inducible protein A Machinery gene
  EL078_RS08910 (NCTC8140_01808) - 1792277..1793479 (-) 1203 WP_033153546.1 MFS transporter -
  EL078_RS08915 (NCTC8140_01809) - 1793602..1794159 (-) 558 WP_164554336.1 DNA-3-methyladenine glycosylase I -
  EL078_RS08920 (NCTC8140_01810) ruvA 1794189..1794782 (-) 594 WP_024344431.1 Holliday junction branch migration protein RuvA Machinery gene
  EL078_RS08925 (NCTC8140_01811) hexB 1794783..1796726 (-) 1944 WP_027968297.1 DNA mismatch repair endonuclease MutL Machinery gene
  EL078_RS08930 (NCTC8140_01812) hexA 1796840..1799410 (-) 2571 WP_126438161.1 DNA mismatch repair protein MutS Machinery gene
  EL078_RS08935 (NCTC8140_01813) - 1799397..1799750 (-) 354 WP_039697773.1 YlbF family regulator -
  EL078_RS08940 (NCTC8140_01814) argR 1799747..1800184 (-) 438 WP_021143308.1 arginine repressor -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72891.01 Da        Isoelectric Point: 5.2853

>NTDB_id=999861 EL078_RS08925 WP_027968297.1 1794783..1796726(-) (hexB) [Streptococcus equinus strain NCTC8140]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENSIDAGSSQITIEIEESGLKKIQVTDNGEGIAQEDVALSLHRHATSK
IKSQADLFRIRTLGFRGEAIPSIASISHFTVKTATADENYGTLLIAKGGEIEKQEPISTPVGTKITVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLAHPEIAFTLINDGRQMTTTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMTLISS
AIAESLRAQDLIPDALENLAKSSTRGLPKPEQTSLPLKQSNLYYDKERHDFFVKSDTVEEQPVQLFNEVDTPVKEVDKQS
SVKYAQRSTQGNLADGEHDDLDFKNKSKINKLLENLDGEESSTFPELDYFGQMHGTYLFAQGNGGLYIIDQHAAQERVKY
EYYRDKIGDVDASLQQLLMPYLFEFSGADFIKLQEKMELLNQVGINLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARQLLVQLSQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRELGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=999861 EL078_RS08925 WP_027968297.1 1794783..1796726(-) (hexB) [Streptococcus equinus strain NCTC8140]
ATGAGTAAAATTATCGAGTTACCAGAGGTTCTAGCCAACCAAATTGCTGCTGGTGAGGTTATTGAACGCCCGGCTAGCGT
GGTCAAGGAATTAGTAGAAAATTCGATTGATGCTGGAAGCAGTCAGATTACGATTGAAATCGAAGAGTCTGGTTTGAAAA
AAATCCAAGTTACTGATAACGGTGAGGGAATTGCTCAAGAGGATGTTGCTCTTAGTTTGCACCGTCACGCGACTAGTAAA
ATTAAAAGTCAAGCCGACCTGTTTCGAATCAGAACGCTTGGTTTCCGTGGCGAAGCCATTCCTTCCATTGCTTCAATCAG
TCATTTTACGGTGAAAACAGCAACGGCTGATGAAAATTATGGGACGCTTTTGATTGCTAAGGGTGGCGAAATTGAAAAAC
AAGAGCCAATCTCAACGCCCGTTGGAACAAAAATTACAGTTGAAAATCTGTTTTACAACACACCAGCTCGTCTTAAGTAT
ATGAAGAGTCTACAGTCAGAGTTGGCACATATTGTTGATGTGGTCAATCGTTTGAGTTTGGCACATCCTGAAATTGCCTT
CACTTTGATTAATGATGGACGTCAGATGACAACGACATCAGGTACTGGAGATTTGCGCCAAGCGATTGCTGGGATTTATG
GCTTAAACACAGCTAAGAAGATGATTGAGATTTCAAATGCAGATCTTGATTTTGAGGTATCAGGTTACATTAGTTTACCT
GAATTGACGCGTGCGAATCGCAATTATATTACGATTTTGATTAACGGACGTTACATCAAAAATTTCTTACTGAATCGTGC
CATCTTGGACGGCTATGGTTCAAAATTGATGGTTGGTCGTTTCCCGATTGCTGTCATTGATATTCAGATTGATCCTTATC
TTGCTGATGTCAATGTTCACCCAACAAAGCAAGAAGTTCGTATCTCAAAAGAAAAAGAACTGATGACTCTCATCAGCTCA
GCTATTGCAGAGAGTTTACGTGCTCAGGATTTGATTCCAGATGCTCTTGAAAATCTAGCTAAGTCAAGCACTCGTGGCTT
GCCTAAACCAGAGCAAACGAGTCTGCCTTTAAAACAATCAAATCTTTATTATGACAAAGAGCGTCACGATTTCTTTGTGA
AATCAGATACTGTTGAAGAGCAGCCAGTTCAGCTGTTTAATGAGGTTGACACACCTGTCAAGGAAGTTGACAAGCAGTCT
TCAGTCAAATACGCACAGCGTTCTACTCAGGGAAACCTTGCAGACGGCGAGCATGATGACCTTGATTTCAAAAATAAATC
TAAAATTAATAAGTTGCTCGAAAATCTTGATGGTGAAGAATCATCAACTTTCCCTGAACTTGATTATTTTGGTCAGATGC
ATGGGACATATCTTTTTGCGCAGGGAAATGGTGGCCTTTATATCATTGACCAACATGCGGCGCAGGAACGTGTTAAATAT
GAATATTATCGTGACAAAATTGGTGATGTCGATGCTTCACTCCAACAATTGCTCATGCCATATTTGTTTGAGTTTTCTGG
AGCAGATTTTATCAAGCTTCAAGAAAAAATGGAGCTTTTAAATCAAGTTGGCATCAATCTAGAACCATATGGGAACAATA
CATTTATTCTTCGTGAACATCCTATTTGGATGAAAGAAGAGGAGATTGAATCGGCTGTTTATGAAATGTGTGATATGTTG
CTTTTGACGAATGAAGTATCTGTCAAAAAATACCGTGCAGAGTTAGCGATTATGATGTCATGTAAACGTTCAATTAAAGC
TAATCACACTCTTGATGATTATTCAGCACGTCAACTTTTAGTGCAATTATCACAATGTAAGAACCCATATAACTGTCCAC
ACGGTCGTCCTGTTCTGGTCAACTTTACCAAATCAGACATGGAAAAGATGTTCCGTCGTATTCAAGAAAATCATACAAGT
TTAAGAGAGTTAGGAAAATACTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-119)

MutL C terminal dimerisation domain (MutL_C)

(449-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70.884

100

0.719