Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   EL086_RS02490 Genome accession   NZ_LR134274
Coordinates   490196..490948 (+) Length   250 a.a.
NCBI ID   WP_038675433.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC8618     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 485196..495948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL086_RS02475 (NCTC8618_02911) - 485443..485733 (+) 291 WP_002885564.1 hypothetical protein -
  EL086_RS02480 (NCTC8618_02912) - 486019..488574 (+) 2556 WP_038675428.1 SH3 domain-containing protein -
  EL086_RS02485 (NCTC8618_02913) - 488626..489875 (-) 1250 Protein_440 ISL3 family transposase -
  EL086_RS02490 (NCTC8618_02914) comE/blpR 490196..490948 (+) 753 WP_038675433.1 response regulator transcription factor Regulator
  EL086_RS02495 (NCTC8618_02915) - 491083..491748 (+) 666 WP_038675435.1 DUF6287 domain-containing protein -
  EL086_RS02500 (NCTC8618_02916) comE/blpR 491996..492730 (+) 735 WP_038675437.1 response regulator transcription factor Regulator
  EL086_RS02505 (NCTC8618_02917) - 492727..494046 (+) 1320 WP_038675438.1 GHKL domain-containing protein -
  EL086_RS02510 (NCTC8618_02918) - 494144..494794 (+) 651 WP_038675440.1 DUF6287 domain-containing protein -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28773.25 Da        Isoelectric Point: 5.6107

>NTDB_id=999560 EL086_RS02490 WP_038675433.1 490196..490948(+) (comE/blpR) [Streptococcus salivarius strain NCTC8618]
MLDIFVLEEDYFQQARLEDAIHKSKQIYILRIGKVDLYDKPNQLLERITERGSHLLFFLDIGSDSDVEGGILVAQQIRER
DPYASIVFITAHPELLPSTFQYRLAALDFIDKNLPDIEYEDRIISDIGLALSKNGLSQIECAFTIDTKHATIQVPFHKIL
YFETSPTVHKVILHTTEEQIEFYGQLSKIVKQDCRLYKCHKSFVVNPENIVRLDKELGIIYFENGESCLVSKAKQKEIVA
RMLVPKPMAV

Nucleotide


Download         Length: 753 bp        

>NTDB_id=999560 EL086_RS02490 WP_038675433.1 490196..490948(+) (comE/blpR) [Streptococcus salivarius strain NCTC8618]
ATGTTGGATATTTTTGTTTTAGAAGAAGATTATTTTCAACAAGCTCGTCTTGAGGATGCCATCCACAAGTCTAAACAAAT
ATATATTTTAAGAATTGGGAAGGTTGATTTATACGATAAACCCAATCAATTATTAGAGCGTATTACGGAAAGGGGCTCGC
ATTTACTGTTTTTTCTAGATATTGGATCTGACAGTGATGTCGAAGGGGGAATATTGGTTGCTCAACAGATTCGTGAGCGA
GATCCGTATGCAAGTATTGTTTTCATCACAGCACATCCCGAACTCCTACCTTCAACCTTTCAGTATCGCTTAGCTGCACT
TGATTTTATTGACAAGAATTTGCCTGATATTGAATATGAAGATAGGATTATTTCTGATATTGGATTAGCACTTTCTAAAA
ATGGTCTGAGCCAAATAGAGTGTGCTTTTACTATAGATACAAAGCATGCAACTATACAAGTTCCTTTTCATAAGATACTC
TATTTTGAAACATCTCCAACAGTTCATAAGGTGATTCTTCATACAACAGAAGAGCAAATTGAGTTCTATGGTCAATTGTC
AAAAATTGTGAAACAAGATTGCAGACTATATAAATGTCATAAATCATTTGTTGTAAATCCCGAAAACATTGTGAGATTGG
ACAAAGAATTAGGTATTATTTATTTTGAAAACGGAGAGTCATGCTTGGTTTCAAAAGCTAAACAAAAAGAGATTGTTGCT
AGGATGCTTGTTCCAAAACCCATGGCAGTTTGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

46.091

97.2

0.448
  comE/comE1 Streptococcus equinus JB1

41.736

96.8

0.404

Multiple sequence alignment