Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   ABD408_RS00275 Genome accession   NZ_CP155735
Coordinates   47863..47961 (+) Length   32 a.a.
NCBI ID   WP_206733287.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 4958/15     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 42863..52961
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABD408_RS00255 (ABD408_00250) purK 42936..44009 (+) 1074 WP_023611330.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  ABD408_RS00260 (ABD408_00255) - 44011..45429 (+) 1419 WP_023612101.1 hypothetical protein -
  ABD408_RS00265 (ABD408_00260) purB 45449..46741 (+) 1293 WP_023612104.1 adenylosuccinate lyase -
  ABD408_RS00270 (ABD408_00265) comR 46872..47783 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  ABD408_RS00275 comS 47863..47961 (+) 99 WP_206733287.1 quorum-sensing system DWW-type pheromone Regulator
  ABD408_RS00280 (ABD408_00270) ruvB 48008..49006 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  ABD408_RS00285 (ABD408_00275) - 49144..49581 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  ABD408_RS00290 (ABD408_00280) - 49604..50005 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  ABD408_RS00295 (ABD408_00285) - 50002..51777 (+) 1776 WP_023612103.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 32 a.a.        Molecular weight: 3980.77 Da        Isoelectric Point: 10.0437

>NTDB_id=998880 ABD408_RS00275 WP_206733287.1 47863..47961(+) (comS) [Streptococcus pyogenes strain 4958/15]
MHVKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 99 bp        

>NTDB_id=998880 ABD408_RS00275 WP_206733287.1 47863..47961(+) (comS) [Streptococcus pyogenes strain 4958/15]
ATCCATGTTAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGT
TGACTGGTGGCGATTATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

96.667

93.75

0.906

  comS Streptococcus pyogenes MGAS315

40

93.75

0.375


Multiple sequence alignment