Detailed information NTG0998201

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ABEG07_RS05650
• Genome accession: NZ_CP155636
• Coordinates: 1189503..1190546 (+)
• Length: 347 a.a.
• NCBI ID: WP_002461334.1
• Uniprot ID: A0A853V5Y6
• Organism: Staphylococcus lugdunensis strain SQ078
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1184503..1195546

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABEG07_RS05625 (ABEG07_05625)	-	1184793..1186154 (-)	1362	WP_002477958.1	FAD-dependent oxidoreductase	-
ABEG07_RS05630 (ABEG07_05630)	-	1186288..1187268 (-)	981	WP_002477959.1	aromatic acid exporter family protein	-
ABEG07_RS05635 (ABEG07_05635)	map	1187513..1188268 (+)	756	WP_002461338.1	type I methionyl aminopeptidase	-
ABEG07_RS05640 (ABEG07_05640)	-	1188394..1188780 (+)	387	WP_002477960.1	hypothetical protein	-
ABEG07_RS05645 (ABEG07_05645)	liaF	1188805..1189506 (+)	702	WP_002461335.1	cell wall-active antibiotics response protein LiaF	-
ABEG07_RS05650 (ABEG07_05650)	vraS	1189503..1190546 (+)	1044	WP_002461334.1	sensor histidine kinase	Regulator
ABEG07_RS05655 (ABEG07_05655)	vraR	1190536..1191165 (+)	630	WP_002461333.1	two-component system response regulator VraR	Regulator
ABEG07_RS05660 (ABEG07_05660)	-	1191338..1192567 (-)	1230	WP_002461332.1	YihY/virulence factor BrkB family protein	-
ABEG07_RS05665 (ABEG07_05665)	-	1192770..1193054 (-)	285	WP_002461330.1	YtxH domain-containing protein	-
ABEG07_RS05670 (ABEG07_05670)	-	1193061..1193525 (-)	465	WP_002477961.1	low molecular weight protein-tyrosine-phosphatase	-
ABEG07_RS05675 (ABEG07_05675)	-	1193689..1193874 (+)	186	WP_002492715.1	DUF1128 domain-containing protein	-
ABEG07_RS05680 (ABEG07_05680)	-	1193887..1195125 (+)	1239	WP_002477963.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39934.41 Da
• Isoelectric Point: 5.9679

>NTDB_id=998201 ABEG07_RS05650 WP_002461334.1 1189503..1190546(+) (vraS) [Staphylococcus lugdunensis strain SQ078]
MNHYIRAIGSMLILVYSLMIAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAFKINQQNDWIKT
QVEHAIEGETVGINDQNIELYNETIDLYHTLVPLNQELHRLRMKTQNLTNENYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHDI
EEFKVPKGLEDHLFRITQEAISNTLRHSKGTKVTVELFNKADYLLLRIQDNGIGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=998201 ABEG07_RS05650 WP_002461334.1 1189503..1190546(+) (vraS) [Staphylococcus lugdunensis strain SQ078]
ATGAACCACTATATTCGAGCAATCGGCTCAATGTTGATACTAGTGTATAGCTTAATGATTGCTTTTCTGTTTATTGATAA
AGTATTCGTTAATATCATTTACTTTCAAGGCATGTTTTATACACAAATATTTGGAATACCAGTATTCCTTTTCTTAAATT
TGGTTATTATTTTATTATGTATTATTGTGGGCTCTATATTAGCTTTTAAAATCAATCAACAAAATGATTGGATCAAAACA
CAAGTAGAGCATGCAATAGAAGGGGAAACAGTTGGTATAAATGATCAAAATATAGAATTGTATAATGAAACAATTGATTT
ATATCATACATTAGTTCCCTTAAATCAAGAGTTACACCGATTAAGAATGAAAACACAAAACTTAACAAATGAAAATTATA
ATTTAAATGATGTAAAAGTGAAAAAAATAATTGAAGACGAACGTCAACGTCTAGCTCGAGAATTACATGATTCAGTGAGC
CAGCAATTATTTGCAGCCAGTATGATGTTATCTGCAATTAAAGAAACAGAGCTAGAACCACCTTTAGATCAACAAATTCC
AGTTTTAGAAAAAATGGTGCAAGATTCACAACTTGAAATGAGAGCGCTCTTATTACATCTAAGACCAATTGGTTTAAAGG
ACAAGTCGTTGGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAGAAAAAAGTACCGATGAAAGTGGTTCACGATATT
GAAGAATTTAAAGTGCCTAAAGGTTTAGAAGATCATTTGTTTAGAATTACTCAAGAAGCCATCTCTAATACTTTAAGACA
TTCAAAAGGAACTAAAGTTACTGTAGAATTATTTAATAAAGCAGATTATTTATTATTAAGAATACAAGATAATGGCATTG
GATTTAATGTTGATGATAAAGTCGAACAAAGTTATGGCTTGAAAAATATGCGCGAACGTGCGTTAGAAATAGGTGCAACA
TTTCATATTGTATCATTGCCTGATTCTGGAACAAGAATAGAGGTTAAAGCACCGTTAAACAAGGAGGATTCACATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A853V5Y6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.066	100	0.911