Detailed information NTG0997512

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: ABC812_RS09765
• Genome accession: NZ_CP155537
• Coordinates: 1887114..1887416 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain DP1322
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1882114..1892416

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC812_RS09730 (ABC812_09725)	rnpA	1882793..1883164 (-)	372	WP_000739246.1	ribonuclease P protein component	-
ABC812_RS09735 (ABC812_09730)	-	1883181..1883312 (-)	132	WP_000768904.1	hypothetical protein	-
ABC812_RS09740 (ABC812_09735)	-	1883313..1884503 (-)	1191	WP_000167757.1	acetate kinase	-
ABC812_RS09745 (ABC812_09740)	comYH	1884554..1885507 (-)	954	WP_000345135.1	class I SAM-dependent methyltransferase	Machinery gene
ABC812_RS09750 (ABC812_09745)	-	1885568..1886162 (-)	595	Protein_1895	methyltransferase domain-containing protein	-
ABC812_RS09755 (ABC812_09750)	comGG/cglG	1886299..1886712 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
ABC812_RS09760 (ABC812_09755)	comGF/cglF	1886690..1887151 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
ABC812_RS09765 (ABC812_09760)	comGE/cglE	1887114..1887416 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
ABC812_RS09770 (ABC812_09765)	comGD/cglD	1887379..1887783 (-)	405	WP_000588026.1	competence type IV pilus minor pilin ComGD	Machinery gene
ABC812_RS09775 (ABC812_09770)	comGC/cglC	1887776..1888102 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
ABC812_RS09780 (ABC812_09775)	comGB/cglB	1888104..1889120 (-)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
ABC812_RS09785 (ABC812_09780)	comGA/cglA/cilD	1889068..1890009 (-)	942	WP_000249564.1	competence type IV pilus ATPase ComGA	Machinery gene
ABC812_RS09790 (ABC812_09785)	-	1890085..1890450 (-)	366	WP_000286415.1	DUF1033 family protein	-
ABC812_RS09795 (ABC812_09790)	-	1890601..1891659 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=997512 ABC812_RS09765 WP_000413382.1 1887114..1887416(-) (comGE/cglE) [Streptococcus pneumoniae strain DP1322]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=997512 ABC812_RS09765 WP_000413382.1 1887114..1887416(-) (comGE/cglE) [Streptococcus pneumoniae strain DP1322]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4