Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ELZ58_RS08370 Genome accession   NZ_LR134091
Coordinates   1671866..1673128 (-) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain NCTC4137     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1666866..1678128
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ58_RS08345 (NCTC4137_01576) - 1667064..1667732 (-) 669 WP_000805950.1 uroporphyrinogen-III synthase -
  ELZ58_RS08350 (NCTC4137_01577) hemC 1667754..1668680 (-) 927 WP_001230226.1 hydroxymethylbilane synthase -
  ELZ58_RS08355 (NCTC4137_01578) ccsA 1668722..1669537 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  ELZ58_RS08360 (NCTC4137_01579) hemA 1669559..1670905 (-) 1347 WP_000545452.1 glutamyl-tRNA reductase -
  ELZ58_RS08365 (NCTC4137_01580) yihA 1671122..1671712 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ELZ58_RS08370 (NCTC4137_01581) clpX 1671866..1673128 (-) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ELZ58_RS08375 (NCTC4137_01582) tig 1673279..1674580 (-) 1302 WP_000127574.1 trigger factor -
  ELZ58_RS08380 - 1674628..1674738 (-) 111 WP_001790560.1 hypothetical protein -
  ELZ58_RS08385 (NCTC4137_01583) - 1674743..1675672 (-) 930 WP_001280020.1 hypothetical protein -
  ELZ58_RS08390 (NCTC4137_01584) - 1675691..1676299 (-) 609 WP_000032657.1 NUDIX domain-containing protein -
  ELZ58_RS08400 (NCTC4137_01585) rplT 1676441..1676797 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  ELZ58_RS08405 (NCTC4137_01586) rpmI 1676844..1677044 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  ELZ58_RS08410 infC 1677073..1677600 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=997496 ELZ58_RS08370 WP_000472293.1 1671866..1673128(-) (clpX) [Staphylococcus aureus strain NCTC4137]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=997496 ELZ58_RS08370 WP_000472293.1 1671866..1673128(-) (clpX) [Staphylococcus aureus strain NCTC4137]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531

Multiple sequence alignment