Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ELZ60_RS06225 Genome accession   NZ_LR134090
Coordinates   1233859..1235121 (+) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain NCTC9555     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1228859..1240121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ60_RS06185 infC 1229387..1229914 (+) 528 WP_001791162.1 translation initiation factor IF-3 -
  ELZ60_RS06190 (NCTC9555_01168) rpmI 1229943..1230143 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  ELZ60_RS06195 (NCTC9555_01169) rplT 1230190..1230546 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  ELZ60_RS06205 (NCTC9555_01170) - 1230688..1231296 (+) 609 WP_000032660.1 NUDIX domain-containing protein -
  ELZ60_RS06210 (NCTC9555_01171) - 1231315..1232244 (+) 930 WP_001280023.1 hypothetical protein -
  ELZ60_RS06215 - 1232249..1232359 (+) 111 WP_001790560.1 hypothetical protein -
  ELZ60_RS06220 (NCTC9555_01172) tig 1232407..1233708 (+) 1302 WP_000127575.1 trigger factor -
  ELZ60_RS06225 (NCTC9555_01173) clpX 1233859..1235121 (+) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ELZ60_RS06230 (NCTC9555_01174) yihA 1235275..1235865 (+) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ELZ60_RS06235 (NCTC9555_01175) hemA 1236082..1237428 (+) 1347 WP_000545460.1 glutamyl-tRNA reductase -
  ELZ60_RS06240 (NCTC9555_01176) ccsA 1237450..1238265 (+) 816 WP_001157329.1 cytochrome c biogenesis protein -
  ELZ60_RS06245 (NCTC9555_01177) hemC 1238307..1239233 (+) 927 WP_001230225.1 hydroxymethylbilane synthase -
  ELZ60_RS06250 (NCTC9555_01178) - 1239255..1239923 (+) 669 WP_000805942.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=997376 ELZ60_RS06225 WP_000472293.1 1233859..1235121(+) (clpX) [Staphylococcus aureus strain NCTC9555]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=997376 ELZ60_RS06225 WP_000472293.1 1233859..1235121(+) (clpX) [Staphylococcus aureus strain NCTC9555]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTTGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCCCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACAACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCTAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531

Multiple sequence alignment