Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ABC811_RS08375 Genome accession   NZ_CP155535
Coordinates   1622375..1623064 (-) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain PJ755/1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1617375..1628064
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC811_RS08345 (ABC811_08345) - 1618114..1618236 (-) 123 Protein_1652 hypothetical protein -
  ABC811_RS08350 (ABC811_08350) - 1618276..1618443 (-) 168 Protein_1653 transposase -
  ABC811_RS08355 (ABC811_08355) - 1619105..1619441 (+) 337 Protein_1654 lanthionine synthetase LanC family protein -
  ABC811_RS08360 (ABC811_08360) - 1619341..1619928 (+) 588 WP_001818729.1 lanthionine synthetase LanC family protein -
  ABC811_RS08365 (ABC811_08365) - 1619971..1621203 (+) 1233 WP_000765667.1 MFS transporter -
  ABC811_RS08370 (ABC811_08370) cbpC 1621321..1622277 (-) 957 WP_000771100.1 choline-binding protein CbpC -
  ABC811_RS08375 (ABC811_08375) covR 1622375..1623064 (-) 690 WP_000518008.1 response regulator transcription factor Regulator
  ABC811_RS08380 (ABC811_08380) gndA 1623076..1624500 (-) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  ABC811_RS08385 (ABC811_08385) mapZ 1624576..1625970 (-) 1395 WP_000039278.1 mid-cell-anchored protein MapZ -
  ABC811_RS08390 (ABC811_08390) - 1625983..1627140 (-) 1158 WP_000711408.1 class I SAM-dependent RNA methyltransferase -
  ABC811_RS08400 (ABC811_08400) gpsB 1627626..1627955 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=997335 ABC811_RS08375 WP_000518008.1 1622375..1623064(-) (covR) [Streptococcus pneumoniae strain PJ755/1]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=997335 ABC811_RS08375 WP_000518008.1 1622375..1623064(-) (covR) [Streptococcus pneumoniae strain PJ755/1]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment