Detailed information
Bioinformatically predicted
Overview
| Name | clpX | Type | Regulator |
| Locus tag | ABC799_RS03485 | Genome accession | NZ_CP155534 |
| Coordinates | 647634..648866 (+) | Length | 410 a.a. |
| NCBI ID | WP_024478652.1 | Uniprot ID | - |
| Organism | Streptococcus pneumoniae strain DCC1476 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 638575..693715 | 647634..648866 | within | 0 |
Gene organization within MGE regions
Location: 638575..693715
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ABC799_RS03430 (ABC799_03430) | ugpC | 638575..639705 (+) | 1131 | WP_000229961.1 | sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC | - |
| ABC799_RS03435 (ABC799_03435) | - | 639852..639998 (-) | 147 | WP_000403100.1 | hypothetical protein | - |
| ABC799_RS03440 (ABC799_03440) | - | 640206..640964 (+) | 759 | WP_001287230.1 | class I SAM-dependent methyltransferase | - |
| ABC799_RS03445 (ABC799_03445) | - | 641051..641563 (+) | 513 | WP_001049323.1 | adenine phosphoribosyltransferase | - |
| ABC799_RS03450 (ABC799_03450) | metA | 641745..642689 (+) | 945 | WP_001122712.1 | homoserine O-succinyltransferase | - |
| ABC799_RS03455 (ABC799_03455) | - | 642698..643375 (+) | 678 | WP_000221614.1 | DnaD domain-containing protein | - |
| ABC799_RS03460 (ABC799_03460) | tpiA | 643473..644231 (+) | 759 | WP_000087897.1 | triose-phosphate isomerase | - |
| ABC799_RS03465 (ABC799_03465) | lytC | 644269..645774 (+) | 1506 | WP_078139284.1 | choline binding-anchored murein hydrolase LytC | - |
| ABC799_RS03470 (ABC799_03470) | - | 646273..646791 (+) | 519 | WP_000229860.1 | Dps family protein | - |
| ABC799_RS03475 (ABC799_03475) | - | 646921..647427 (+) | 507 | WP_000162467.1 | dihydrofolate reductase | - |
| ABC799_RS03480 (ABC799_03480) | - | 647427..647597 (+) | 171 | WP_000442260.1 | hypothetical protein | - |
| ABC799_RS03485 (ABC799_03485) | clpX | 647634..648866 (+) | 1233 | WP_024478652.1 | ATP-dependent Clp protease ATP-binding subunit ClpX | Regulator |
| ABC799_RS03490 (ABC799_03490) | yihA | 648875..649462 (+) | 588 | WP_000422599.1 | ribosome biogenesis GTP-binding protein YihA/YsxC | - |
| ABC799_RS03495 (ABC799_03495) | - | 649473..649853 (+) | 381 | WP_001140412.1 | RidA family protein | - |
| ABC799_RS03500 (ABC799_03500) | rapZ | 649905..650795 (+) | 891 | WP_000163035.1 | RNase adapter RapZ | - |
| ABC799_RS03505 (ABC799_03505) | - | 650792..651769 (+) | 978 | WP_001231086.1 | YvcK family protein | - |
| ABC799_RS03510 (ABC799_03510) | whiA | 651766..652677 (+) | 912 | WP_000011306.1 | DNA-binding protein WhiA | - |
| ABC799_RS03515 (ABC799_03515) | - | 652765..653892 (-) | 1128 | WP_000266847.1 | site-specific integrase | - |
| ABC799_RS03520 (ABC799_03520) | - | 654034..654414 (-) | 381 | WP_000151192.1 | ImmA/IrrE family metallo-endopeptidase | - |
| ABC799_RS03525 (ABC799_03525) | - | 654637..655731 (-) | 1095 | WP_000156313.1 | hypothetical protein | - |
| ABC799_RS03530 (ABC799_03530) | - | 655733..656086 (-) | 354 | WP_000493111.1 | helix-turn-helix transcriptional regulator | - |
| ABC799_RS03535 (ABC799_03535) | - | 656484..656576 (-) | 93 | WP_000970295.1 | type I toxin-antitoxin system Fst family toxin | - |
| ABC799_RS03540 (ABC799_03540) | - | 656799..656888 (-) | 90 | WP_001810072.1 | hypothetical protein | - |
| ABC799_RS03545 (ABC799_03545) | - | 657112..657351 (-) | 240 | WP_000142893.1 | hypothetical protein | - |
| ABC799_RS03550 (ABC799_03550) | - | 657416..657607 (+) | 192 | WP_001112859.1 | DNA-binding protein | - |
| ABC799_RS03555 (ABC799_03555) | - | 657790..657981 (-) | 192 | WP_000834564.1 | hypothetical protein | - |
| ABC799_RS03560 (ABC799_03560) | - | 658322..658594 (+) | 273 | WP_000454230.1 | hypothetical protein | - |
| ABC799_RS03565 (ABC799_03565) | - | 658591..658785 (+) | 195 | WP_001050924.1 | hypothetical protein | - |
| ABC799_RS03570 (ABC799_03570) | - | 658785..658973 (+) | 189 | WP_001853687.1 | hypothetical protein | - |
| ABC799_RS03575 (ABC799_03575) | - | 658985..659326 (+) | 342 | WP_000189400.1 | hypothetical protein | - |
| ABC799_RS03580 (ABC799_03580) | - | 659327..659557 (+) | 231 | WP_000252078.1 | hypothetical protein | - |
| ABC799_RS03585 (ABC799_03585) | - | 659571..660293 (+) | 723 | WP_000544342.1 | HNH endonuclease signature motif containing protein | - |
| ABC799_RS03590 (ABC799_03590) | - | 660286..660768 (+) | 483 | WP_000157805.1 | siphovirus Gp157 family protein | - |
| ABC799_RS03595 (ABC799_03595) | - | 660777..661127 (+) | 351 | WP_223842484.1 | hypothetical protein | - |
| ABC799_RS03600 (ABC799_03600) | - | 661127..661612 (+) | 486 | WP_000696057.1 | hypothetical protein | - |
| ABC799_RS03605 (ABC799_03605) | - | 661575..662768 (+) | 1194 | WP_000028860.1 | DEAD/DEAH box helicase family protein | - |
| ABC799_RS03610 (ABC799_03610) | - | 662787..663104 (+) | 318 | WP_001044592.1 | hypothetical protein | - |
| ABC799_RS03615 (ABC799_03615) | - | 663104..663880 (+) | 777 | WP_000885998.1 | AAA family ATPase | - |
| ABC799_RS03620 (ABC799_03620) | - | 663900..664403 (+) | 504 | WP_000054337.1 | hypothetical protein | - |
| ABC799_RS03625 (ABC799_03625) | - | 664576..665397 (+) | 822 | WP_000097191.1 | bifunctional DNA primase/polymerase | - |
| ABC799_RS03630 (ABC799_03630) | - | 665400..666743 (+) | 1344 | WP_000580029.1 | virulence-associated E family protein | - |
| ABC799_RS03635 (ABC799_03635) | - | 667036..667188 (+) | 153 | WP_000122743.1 | hypothetical protein | - |
| ABC799_RS03640 (ABC799_03640) | - | 667188..667526 (+) | 339 | WP_000119453.1 | hypothetical protein | - |
| ABC799_RS03645 (ABC799_03645) | - | 667677..667991 (+) | 315 | WP_000391853.1 | hypothetical protein | - |
| ABC799_RS03650 (ABC799_03650) | - | 667993..668520 (+) | 528 | WP_001041163.1 | DUF1642 domain-containing protein | - |
| ABC799_RS03655 (ABC799_03655) | - | 668582..668899 (+) | 318 | WP_001268499.1 | hypothetical protein | - |
| ABC799_RS03660 (ABC799_03660) | - | 669017..669439 (+) | 423 | WP_001030244.1 | DUF1492 domain-containing protein | - |
| ABC799_RS03670 (ABC799_03670) | - | 670709..671221 (+) | 513 | WP_000863690.1 | terminase small subunit | - |
| ABC799_RS03675 (ABC799_03675) | - | 671199..672497 (+) | 1299 | WP_000084412.1 | PBSX family phage terminase large subunit | - |
| ABC799_RS03680 (ABC799_03680) | - | 672509..673978 (+) | 1470 | WP_000285392.1 | phage portal protein | - |
| ABC799_RS03685 (ABC799_03685) | - | 673887..675524 (+) | 1638 | WP_164993540.1 | minor capsid protein | - |
| ABC799_RS03690 (ABC799_03690) | - | 675526..675735 (+) | 210 | WP_000651746.1 | hypothetical protein | - |
| ABC799_RS03695 (ABC799_03695) | - | 675732..676145 (+) | 414 | WP_000565273.1 | HD domain-containing protein | - |
| ABC799_RS03700 (ABC799_03700) | - | 676187..676360 (+) | 174 | WP_000356388.1 | hypothetical protein | - |
| ABC799_RS03705 (ABC799_03705) | - | 676627..677151 (+) | 525 | WP_001288018.1 | DUF4355 domain-containing protein | - |
| ABC799_RS03710 (ABC799_03710) | - | 677174..678199 (+) | 1026 | WP_000863393.1 | carbohydrate-binding protein | - |
| ABC799_RS03715 (ABC799_03715) | - | 678209..678397 (+) | 189 | WP_000669348.1 | hypothetical protein | - |
| ABC799_RS03720 (ABC799_03720) | - | 678399..678710 (+) | 312 | WP_000021218.1 | phage head-tail connector protein | - |
| ABC799_RS03725 (ABC799_03725) | - | 678691..679029 (+) | 339 | WP_000478943.1 | hypothetical protein | - |
| ABC799_RS03730 (ABC799_03730) | - | 679004..679519 (+) | 516 | WP_000015940.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| ABC799_RS03735 (ABC799_03735) | - | 679516..679884 (+) | 369 | WP_000608235.1 | hypothetical protein | - |
| ABC799_RS03740 (ABC799_03740) | - | 679887..680300 (+) | 414 | WP_000880665.1 | phage tail tube protein | - |
| ABC799_RS03745 (ABC799_03745) | - | 680305..680685 (+) | 381 | WP_001185631.1 | DUF6096 family protein | - |
| ABC799_RS03750 (ABC799_03750) | - | 680724..681074 (+) | 351 | WP_000478007.1 | hypothetical protein | - |
| ABC799_RS03755 (ABC799_03755) | - | 681061..684654 (+) | 3594 | WP_000212166.1 | hypothetical protein | - |
| ABC799_RS03760 (ABC799_03760) | - | 684663..685013 (+) | 351 | WP_000068023.1 | DUF6711 family protein | - |
| ABC799_RS03765 (ABC799_03765) | - | 685018..691461 (+) | 6444 | WP_000339678.1 | tail fiber domain-containing protein | - |
| ABC799_RS03770 (ABC799_03770) | - | 691458..691574 (+) | 117 | Protein_694 | dihydrodipicolinate reductase | - |
| ABC799_RS03775 (ABC799_03775) | - | 691555..691758 (+) | 204 | WP_001091119.1 | hypothetical protein | - |
| ABC799_RS03780 (ABC799_03780) | - | 691761..692111 (+) | 351 | WP_000852249.1 | hypothetical protein | - |
| ABC799_RS03785 (ABC799_03785) | - | 692121..692420 (+) | 300 | WP_001810279.1 | hypothetical protein | - |
| ABC799_RS03790 (ABC799_03790) | - | 692424..692759 (+) | 336 | WP_001186239.1 | phage holin | - |
| ABC799_RS03795 (ABC799_03795) | - | 692759..693715 (+) | 957 | WP_000350525.1 | N-acetylmuramoyl-L-alanine amidase family protein | - |
Sequence
Protein
Download Length: 410 a.a. Molecular weight: 45726.24 Da Isoelectric Point: 4.4240
>NTDB_id=997263 ABC799_RS03485 WP_024478652.1 647634..648866(+) (clpX) [Streptococcus pneumoniae strain DCC1476]
MPTTRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA
MPTTRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA
Nucleotide
Download Length: 1233 bp
>NTDB_id=997263 ABC799_RS03485 WP_024478652.1 647634..648866(+) (clpX) [Streptococcus pneumoniae strain DCC1476]
ATGCCTACAACTAGGAATAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCTGGGAACAACGCCTTTATCTGTAATGAATGTGTAGAGTTAGCCCAGGAAATCATTCGGGAAGAGTTGGCGGAAGAAG
TCTTGGCAGACTTGTCTGAGGTACCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCAGTTTACAATCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCGGAAGA
TGTAGATTTGCAGAAGTCAAACATCTTGATGATTGGCCCAACCGGTTCAGGGAAAACTTTCCTTGCTCAGACCTTGGCTA
AGAGCTTAAATGTGCCTTTTGCGATTGCGGATGCGACAGCTCTTACCGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATACTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTAATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG
ATGCCTACAACTAGGAATAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCTGGGAACAACGCCTTTATCTGTAATGAATGTGTAGAGTTAGCCCAGGAAATCATTCGGGAAGAGTTGGCGGAAGAAG
TCTTGGCAGACTTGTCTGAGGTACCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCAGTTTACAATCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCGGAAGA
TGTAGATTTGCAGAAGTCAAACATCTTGATGATTGGCCCAACCGGTTCAGGGAAAACTTTCCTTGCTCAGACCTTGGCTA
AGAGCTTAAATGTGCCTTTTGCGATTGCGGATGCGACAGCTCTTACCGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATACTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTAATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpX | Streptococcus mutans UA159 |
86.341 |
100 |
0.863 |
| clpX | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
57.214 |
98.049 |
0.561 |