Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GZL_RS30900 Genome accession   NZ_CP003987
Coordinates   7228231..7228914 (+) Length   227 a.a.
NCBI ID   WP_052286966.1    Uniprot ID   A0ABY8AE84
Organism   Streptomyces sp. 769     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7223231..7233914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GZL_RS30885 (GZL_06706) - 7224852..7225571 (-) 720 WP_039637636.1 transglycosylase SLT domain-containing protein -
  GZL_RS30890 (GZL_06707) - 7225909..7226637 (-) 729 WP_203232601.1 nitroreductase family protein -
  GZL_RS30895 (GZL_06708) - 7227093..7228238 (+) 1146 WP_039637638.1 GAF domain-containing sensor histidine kinase -
  GZL_RS30900 (GZL_06709) vraR 7228231..7228914 (+) 684 WP_052286966.1 response regulator transcription factor Regulator
  GZL_RS30905 (GZL_06710) - 7229131..7229343 (+) 213 WP_039641913.1 chaplin -
  GZL_RS30910 (GZL_06711) - 7229507..7229752 (+) 246 WP_039637639.1 chaplin -
  GZL_RS30915 (GZL_06712) - 7229855..7230670 (-) 816 WP_039637640.1 hypothetical protein -
  GZL_RS30920 (GZL_06713) - 7230761..7231573 (+) 813 WP_078875947.1 ABC transporter ATP-binding protein -
  GZL_RS30925 (GZL_06714) - 7231711..7232124 (+) 414 WP_039637641.1 NfeD family protein -
  GZL_RS30930 (GZL_06715) - 7232224..7233156 (+) 933 WP_039637642.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24208.47 Da        Isoelectric Point: 5.3618

>NTDB_id=99725 GZL_RS30900 WP_052286966.1 7228231..7228914(+) (vraR) [Streptomyces sp. 769]
MADHTRGGTERATGEGRAIRVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGAEGIAATEQLRPDVVLMDIKMPGMDGI
EALRQLRTLDNPAKVLVVTSFTEQRTVVPALRAGAAGYVYKDIDPDALAGAIRSVHAGHVLLQPEVAGALLSQEDGNGGQ
GRGSSLTEREGEVLGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGIGA

Nucleotide


Download         Length: 684 bp        

>NTDB_id=99725 GZL_RS30900 WP_052286966.1 7228231..7228914(+) (vraR) [Streptomyces sp. 769]
GTGGCTGACCACACGCGGGGCGGTACGGAACGGGCCACGGGCGAAGGGCGCGCGATCCGCGTGCTGCTGGTCGACGATCA
CCAGGTGGTGCGCCGCGGCCTGCGGACGTTCCTGGAGGTCCAGGACGACATCGAGGTGGTGGGGGAGGCGTCGGACGGTG
CCGAGGGCATCGCCGCCACCGAGCAACTGCGGCCGGACGTCGTCCTGATGGACATCAAGATGCCCGGCATGGACGGCATC
GAGGCCCTCCGCCAGCTCCGCACCCTCGACAACCCGGCCAAGGTGCTGGTCGTCACCAGCTTCACCGAGCAGCGCACCGT
CGTCCCGGCCCTGCGCGCCGGCGCGGCCGGCTACGTCTACAAGGACATCGACCCCGACGCCCTGGCCGGCGCCATCCGCT
CGGTGCACGCCGGGCACGTCCTGCTCCAGCCCGAGGTGGCCGGCGCGCTGCTCTCCCAGGAGGACGGCAACGGCGGCCAG
GGACGCGGGAGTTCGCTCACCGAGCGGGAGGGCGAGGTGCTGGGCCTGATCGCGGACGGCCGCTCCAACCGCGAGATCGC
CCGCGCGCTGGTGCTGTCGGAGAAGACCGTCAAGACCCACGTCTCCAACATCCTGATGAAACTCGACCTCGCCGACCGCA
CCCAGGCCGCCCTGTGGGCCGTGCGACACGGCATCGGGGCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(21-132)

Bacterial regulatory proteins, luxR family (GerE)

(164-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.445

92.952

0.432
  degU Bacillus subtilis subsp. subtilis str. 168

38.914

97.357

0.379

Multiple sequence alignment