Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ELZ49_RS08735 Genome accession   NZ_LR134086
Coordinates   1750032..1751294 (-) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain NCTC13142     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1745032..1756294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ49_RS08710 (NCTC13142_01688) - 1745230..1745898 (-) 669 WP_000805956.1 uroporphyrinogen-III synthase -
  ELZ49_RS08715 (NCTC13142_01689) hemC 1745920..1746846 (-) 927 WP_001230226.1 hydroxymethylbilane synthase -
  ELZ49_RS08720 (NCTC13142_01690) ccsA 1746888..1747703 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  ELZ49_RS08725 (NCTC13142_01691) hemA 1747725..1749071 (-) 1347 WP_000545453.1 glutamyl-tRNA reductase -
  ELZ49_RS08730 (NCTC13142_01692) yihA 1749288..1749878 (-) 591 WP_000867695.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ELZ49_RS08735 (NCTC13142_01693) clpX 1750032..1751294 (-) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ELZ49_RS08740 (NCTC13142_01694) tig 1751445..1752746 (-) 1302 WP_000127572.1 trigger factor -
  ELZ49_RS08745 - 1752794..1752904 (-) 111 WP_001790560.1 hypothetical protein -
  ELZ49_RS08750 (NCTC13142_01695) - 1752909..1753838 (-) 930 WP_001280010.1 hypothetical protein -
  ELZ49_RS08755 (NCTC13142_01696) - 1753857..1754465 (-) 609 WP_000032657.1 NUDIX domain-containing protein -
  ELZ49_RS08765 (NCTC13142_01697) rplT 1754607..1754963 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  ELZ49_RS08770 (NCTC13142_01698) rpmI 1755010..1755210 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  ELZ49_RS08775 infC 1755239..1755766 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=997230 ELZ49_RS08735 WP_000472293.1 1750032..1751294(-) (clpX) [Staphylococcus aureus strain NCTC13142]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=997230 ELZ49_RS08735 WP_000472293.1 1750032..1751294(-) (clpX) [Staphylococcus aureus strain NCTC13142]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAATA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
GTTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACCTTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGCTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGCACAACTGCGAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531