Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GZL_RS28115 Genome accession   NZ_CP003987
Coordinates   6579278..6579958 (-) Length   226 a.a.
NCBI ID   WP_039636878.1    Uniprot ID   -
Organism   Streptomyces sp. 769     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6574278..6584958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GZL_RS28095 (GZL_06105) - 6574947..6575462 (+) 516 WP_039636872.1 MerR family transcriptional regulator -
  GZL_RS28100 (GZL_06106) - 6575468..6576454 (+) 987 WP_039636874.1 aldo/keto reductase -
  GZL_RS28105 (GZL_06107) - 6576533..6577846 (-) 1314 WP_239010153.1 acyltransferase -
  GZL_RS28110 (GZL_06108) - 6577893..6579059 (-) 1167 WP_039636876.1 alpha/beta hydrolase -
  GZL_RS28115 (GZL_06109) vraR 6579278..6579958 (-) 681 WP_039636878.1 response regulator transcription factor Regulator
  GZL_RS28120 (GZL_06110) - 6579955..6581370 (-) 1416 WP_039636882.1 sensor histidine kinase -
  GZL_RS28125 (GZL_06111) - 6581498..6582376 (-) 879 WP_039636884.1 DUF4429 domain-containing protein -
  GZL_RS28130 (GZL_06112) - 6582577..6583791 (-) 1215 WP_039636886.1 alpha/beta hydrolase -
  GZL_RS28135 (GZL_06113) - 6583964..6584662 (-) 699 WP_039636888.1 TetR family transcriptional regulator -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24471.27 Da        Isoelectric Point: 6.1241

>NTDB_id=99719 GZL_RS28115 WP_039636878.1 6579278..6579958(-) (vraR) [Streptomyces sp. 769]
MTTRVIIVDDQAMVRAGFAALLAAQSDIDVVGDAADGAGGVRLSRQVHPDVVLMDVRMPEMDGLEAARQLLHPPIGVTHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLISAVRVVAAGEALLAPSVTRRLIADFARQRPAPRTDRTALRLNG
LTPRETEVLELIARGLSNQEIAERLILAEQTVKTHIGRVLAKLELRDRAQAVIFAYESGLVSPGER

Nucleotide


Download         Length: 681 bp        

>NTDB_id=99719 GZL_RS28115 WP_039636878.1 6579278..6579958(-) (vraR) [Streptomyces sp. 769]
ATGACGACCCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCGGGTTTCGCCGCGCTGCTCGCCGCGCAGAGCGA
CATCGACGTGGTGGGCGACGCTGCGGACGGCGCCGGGGGCGTCCGGCTGAGCCGGCAGGTGCACCCCGACGTGGTGCTGA
TGGACGTCCGGATGCCGGAGATGGACGGGCTGGAGGCGGCCCGTCAGCTGCTCCACCCGCCGATCGGGGTCACCCACCGC
CCGAAGGTGCTGATGCTGACCACCTTCGACGTCGACGACTACGTCTACGAGGCACTGCGGGCGGGCGCGTCCGGTTTCCT
GCTCAAGGACGCGCCGCCGGCCGACCTGATCTCCGCGGTCCGGGTGGTGGCGGCCGGGGAGGCGCTGCTCGCGCCGTCGG
TGACCCGCCGGCTGATCGCCGACTTCGCCCGCCAGCGGCCGGCGCCCCGTACGGACCGCACCGCGCTGCGGCTCAACGGC
CTCACCCCGCGCGAGACGGAGGTGCTGGAGCTGATCGCCCGCGGTCTGTCCAATCAGGAGATCGCCGAGCGGCTGATCCT
CGCCGAGCAGACCGTGAAGACCCATATCGGCCGGGTGCTGGCCAAGTTGGAGCTGCGCGACCGCGCCCAGGCGGTGATCT
TCGCCTATGAGTCGGGGCTGGTCTCACCCGGCGAGCGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(161-215)

Response regulator receiver domain (Response_reg)

(5-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.152

98.673

0.416
  degU Bacillus subtilis subsp. subtilis str. 168

37.931

100

0.389

Multiple sequence alignment