Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ABC810_RS03600 Genome accession   NZ_CP155532
Coordinates   696321..697553 (+) Length   410 a.a.
NCBI ID   WP_000106354.1    Uniprot ID   A0A4M6D977
Organism   Streptococcus pneumoniae strain SP264     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 691321..702553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC810_RS03570 (ABC810_03565) - 691391..692068 (+) 678 WP_000221614.1 DnaD domain-containing protein -
  ABC810_RS03575 (ABC810_03570) tpiA 692166..692924 (+) 759 WP_000087897.1 triose-phosphate isomerase -
  ABC810_RS03580 (ABC810_03575) lytC 692962..694467 (+) 1506 WP_012386833.1 choline binding-anchored murein hydrolase LytC -
  ABC810_RS03585 (ABC810_03580) - 694965..695483 (+) 519 WP_000229856.1 Dps family protein -
  ABC810_RS03590 (ABC810_03585) - 695613..696119 (+) 507 WP_000162437.1 dihydrofolate reductase -
  ABC810_RS03595 (ABC810_03590) - 696119..696289 (+) 171 WP_000442276.1 hypothetical protein -
  ABC810_RS03600 (ABC810_03595) clpX 696321..697553 (+) 1233 WP_000106354.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ABC810_RS03605 (ABC810_03600) yihA 697562..698149 (+) 588 WP_000422605.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ABC810_RS03610 (ABC810_03605) - 698160..698540 (+) 381 WP_001140412.1 RidA family protein -
  ABC810_RS03615 (ABC810_03610) rapZ 698592..699482 (+) 891 WP_000163035.1 RNase adapter RapZ -
  ABC810_RS03620 (ABC810_03615) - 699479..700456 (+) 978 WP_001231086.1 YvcK family protein -
  ABC810_RS03625 (ABC810_03620) whiA 700453..701364 (+) 912 WP_000011276.1 DNA-binding protein WhiA -
  ABC810_RS03630 (ABC810_03625) - 701398..702366 (-) 969 WP_000080998.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45713.24 Da        Isoelectric Point: 4.4550

>NTDB_id=997108 ABC810_RS03600 WP_000106354.1 696321..697553(+) (clpX) [Streptococcus pneumoniae strain SP264]
MSTNRKNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=997108 ABC810_RS03600 WP_000106354.1 696321..697553(+) (clpX) [Streptococcus pneumoniae strain SP264]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCTGGCAACAATGCCTTTATTTGTAATGAATGCGTGGAGCTAGCTCAAGAAATTATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTACCAAAACCAATCGAACTCCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAATCATTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATCTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCTCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCGATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTAGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGCTGCTGACTTTAACATTGAGCGTGCAGAACGTGGGATTATCTACGTGGATGAAATTGA
CAAGATTGCTAAAAAGAGCGAGAATGTATCGATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTCCTCAAGA
TTATCGAGGGAACCGTCGCAAGCGTACCTCCTCAAGGTGGTCGCAAGCATCCACAACAAGAGATGATTCAAGTGGATACT
AAAAATATCCTCTTTATCGTGGGTGGTGCCTTTGATGGCATTGAAGAAATCGTCAAACAACGTCTTGGAGAAAAAGTCAT
CGGATTTGGTCAAAATAACAAGGCGATTGATGAAAACAGCTCTTACATGCAAGAAATCATCGCAGAGGATATTCAAAAAT
TTGGTATTATCCCTGAGTTAATTGGACGCTTGCCTGTTTTTGCTGCTCTTGAGCAATTGACGGTCGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTCAAACAGTACCAAACCTTGCTTTCTTATGATGATGTCGAGTTGGAATTTGA
CGACGAAGCCCTACAAGAGATTGCTAATAAAGCCATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCTATTATCGAAG
AAACAATGCTAGATGTCATGTTTGAAGTACCGAGTCAGGAAAATGTGAAATTGGTCCGCATCACTAAAGAAGCTGTTGAT
GGAACGGATAAACCAATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4M6D977

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.829

100

0.868
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.463

98.049

0.563

Multiple sequence alignment