Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ABC803_RS08970 Genome accession   NZ_CP155531
Coordinates   1738552..1739241 (-) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain SN36255     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1733552..1744241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC803_RS08945 (ABC803_08945) - 1734238..1734596 (+) 359 Protein_1723 lanthionine synthetase LanC family protein -
  ABC803_RS08950 (ABC803_08950) - 1734496..1734966 (+) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  ABC803_RS08955 (ABC803_08955) - 1735125..1736357 (+) 1233 WP_000765684.1 MFS transporter -
  ABC803_RS08960 (ABC803_08960) cbpJ 1736475..1737473 (-) 999 WP_000771129.1 choline-binding protein CbpJ -
  ABC803_RS08965 (ABC803_08965) cbpC 1737492..1738454 (-) 963 WP_000698035.1 choline-binding protein CbpC -
  ABC803_RS08970 (ABC803_08970) covR 1738552..1739241 (-) 690 WP_000518011.1 response regulator transcription factor Regulator
  ABC803_RS08975 (ABC803_08975) gndA 1739253..1740677 (-) 1425 WP_000158792.1 NADP-dependent phosphogluconate dehydrogenase -
  ABC803_RS08980 (ABC803_08980) mapZ 1740753..1742147 (-) 1395 WP_000039290.1 mid-cell-anchored protein MapZ -
  ABC803_RS08985 (ABC803_08985) - 1742160..1743317 (-) 1158 WP_000711398.1 class I SAM-dependent RNA methyltransferase -
  ABC803_RS08995 (ABC803_08995) gpsB 1743803..1744144 (-) 342 WP_000200644.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=997056 ABC803_RS08970 WP_000518011.1 1738552..1739241(-) (covR) [Streptococcus pneumoniae strain SN36255]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=997056 ABC803_RS08970 WP_000518011.1 1738552..1739241(-) (covR) [Streptococcus pneumoniae strain SN36255]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment