Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ELZ47_RS02650 Genome accession   NZ_LR134002
Coordinates   529271..529903 (+) Length   210 a.a.
NCBI ID   WP_009659067.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC 10904     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 524271..534903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ47_RS02630 (NCTC10904_00520) - 524852..525592 (+) 741 WP_002893499.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ELZ47_RS02635 (NCTC10904_00521) stkP 525589..527439 (+) 1851 WP_126435198.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ELZ47_RS02640 (NCTC10904_00522) liaF 527582..528277 (+) 696 WP_002893496.1 cell wall-active antibiotics response protein LiaF -
  ELZ47_RS02645 (NCTC10904_00523) - 528274..529293 (+) 1020 WP_126435200.1 sensor histidine kinase -
  ELZ47_RS02650 (NCTC10904_00524) vraR 529271..529903 (+) 633 WP_009659067.1 response regulator transcription factor Regulator
  ELZ47_RS02655 (NCTC10904_00525) - 529943..531343 (+) 1401 WP_125331610.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ELZ47_RS02660 (NCTC10904_00526) - 531343..531705 (+) 363 WP_002901252.1 S1 RNA-binding domain-containing protein -
  ELZ47_RS02665 (NCTC10904_00527) cysK 531811..532740 (-) 930 WP_125331608.1 cysteine synthase A -
  ELZ47_RS02670 (NCTC10904_00528) - 532836..533474 (-) 639 WP_125331606.1 YigZ family protein -
  ELZ47_RS02675 (NCTC10904_00529) comFA/cflA 533530..534828 (+) 1299 WP_125331604.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23691.30 Da        Isoelectric Point: 5.0322

>NTDB_id=996679 ELZ47_RS02650 WP_009659067.1 529271..529903(+) (vraR) [Streptococcus sanguinis strain NCTC 10904]
MKILLVDDHQMVRLGLKSYLELQDGIAEVSEAVNGKEGVEQALASRPDVIIMDIVMPEMNGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAHGYMLKTSSAEEILRAVKKVAKGEFAIETEVSKKVEYHRNHIELHEDLTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=996679 ELZ47_RS02650 WP_009659067.1 529271..529903(+) (vraR) [Streptococcus sanguinis strain NCTC 10904]
ATGAAGATATTGTTAGTGGATGACCATCAGATGGTCAGATTGGGATTGAAAAGTTACCTGGAACTGCAAGATGGTATAGC
TGAAGTATCTGAAGCAGTCAATGGTAAAGAAGGCGTTGAGCAAGCTTTAGCAAGTCGTCCGGATGTGATTATCATGGATA
TCGTCATGCCTGAGATGAATGGGATTGAAGCGACACTGGCCATTTTGAAAGAGTGGCCGGAAGCAAAGATTCTGATTTTG
ACTTCTTATCTGGATAATGAAAAAATTTATCCTGTTCTGGATGCAGGCGCTCATGGATACATGCTTAAGACTTCCAGCGC
TGAAGAAATTCTCCGTGCCGTCAAAAAAGTGGCCAAGGGAGAATTTGCCATTGAAACAGAGGTCAGCAAGAAAGTGGAGT
ATCATCGCAACCATATTGAACTTCACGAGGATTTGACAGCTCGTGAGCGTGATATTTTAGGGCTTTTGGCCAAGGGTTAT
GAAAATCAACGAATTGCGGATGAACTCTTTATTTCCCTCAAAACGGTCAAGACTCATGTCTCCAATATCCTGTCCAAATT
GGAGGTGAGCGACCGCACTCAGGCAGTTGTTTATGCTTTTCAGCACCATCTTGTCCCACAAGAAGATTTTTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.427

98.095

0.514
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414