Detailed information NTG0099666

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QMM73_RS13525
• Genome accession: NZ_AP027135
• Coordinates: 2704530..2705417 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain JP089
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2699530..2710417

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMM73_RS13495	-	2699548..2699640 (+)	93	WP_010956583.1	hypothetical protein	-
QMM73_RS13500 (JP089_25130)	-	2699748..2700245 (-)	498	WP_001065268.1	glutathione peroxidase	-
QMM73_RS13505 (JP089_25140)	-	2700255..2700515 (-)	261	WP_001791974.1	hypothetical protein	-
QMM73_RS13510	-	2700898..2701011 (-)	114	WP_011447078.1	hypothetical protein	-
QMM73_RS13515 (JP089_25150)	-	2701670..2703670 (-)	2001	WP_000776751.1	ABC transporter permease	-
QMM73_RS13520 (JP089_25160)	-	2703667..2704422 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QMM73_RS13525 (JP089_25170)	braS	2704530..2705417 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QMM73_RS13530 (JP089_25180)	braR	2705428..2706093 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QMM73_RS13535 (JP089_25190)	-	2706119..2706319 (-)	201	WP_000604727.1	hypothetical protein	-
QMM73_RS13540 (JP089_25200)	-	2706517..2707941 (+)	1425	WP_072507158.1	alkaline phosphatase	-
QMM73_RS13970	-	2708001..2708102 (-)	102	WP_000731976.1	SE2200 family small protein	-
QMM73_RS13550 (JP089_25210)	-	2708224..2708679 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QMM73_RS13555 (JP089_25220)	-	2708924..2709685 (-)	762	WP_000323446.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=99666 QMM73_RS13525 WP_000143425.1 2704530..2705417(-) (braS) [Staphylococcus aureus strain JP089]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=99666 QMM73_RS13525 WP_000143425.1 2704530..2705417(-) (braS) [Staphylococcus aureus strain JP089]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1