Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GZL_RS04215 Genome accession   NZ_CP003987
Coordinates   1110124..1110795 (-) Length   223 a.a.
NCBI ID   WP_039629552.1    Uniprot ID   -
Organism   Streptomyces sp. 769     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1105124..1115795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GZL_RS04185 (GZL_00985) - 1105508..1106143 (+) 636 WP_239009924.1 class I SAM-dependent methyltransferase -
  GZL_RS04190 (GZL_00986) - 1106140..1107459 (+) 1320 WP_039629546.1 salicylate synthase -
  GZL_RS04195 (GZL_00988) - 1107799..1108173 (-) 375 WP_039629547.1 MmcQ/YjbR family DNA-binding protein -
  GZL_RS04200 (GZL_00989) - 1108248..1109180 (-) 933 WP_039640104.1 SDR family oxidoreductase -
  GZL_RS04205 (GZL_00990) - 1109368..1109763 (+) 396 WP_039629548.1 nuclear transport factor 2 family protein -
  GZL_RS04210 - 1109909..1110103 (+) 195 Protein_895 pyridoxamine 5'-phosphate oxidase family protein -
  GZL_RS04215 (GZL_00992) vraR 1110124..1110795 (-) 672 WP_039629552.1 response regulator transcription factor Regulator
  GZL_RS04220 (GZL_00993) - 1110798..1112030 (-) 1233 WP_039629554.1 sensor histidine kinase -
  GZL_RS04225 (GZL_00994) - 1112367..1113542 (-) 1176 WP_039640105.1 FAD-dependent oxidoreductase -
  GZL_RS04230 (GZL_00995) - 1113551..1113745 (-) 195 WP_039629555.1 ferredoxin -
  GZL_RS04235 (GZL_00996) - 1113812..1115008 (-) 1197 WP_039640106.1 cytochrome P450 -
  GZL_RS44205 (GZL_00997) - 1115014..1115697 (-) 684 WP_239009925.1 DUF3159 domain-containing protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 23699.29 Da        Isoelectric Point: 4.6160

>NTDB_id=99666 GZL_RS04215 WP_039629552.1 1110124..1110795(-) (vraR) [Streptomyces sp. 769]
MTIRVLLADDQALLRGTFRMLLDSAPDMEVVAEAATGREAVELARSHRADLVLMDIRMPDLDGLAATRLISDDENLAGVK
VLVLTTFENDEYVAEALRAGASGFLGKGINPDELLDAIRVVAAGDSLLSPTATKALIARFLAQPAPPDRAAAPLLAALTP
REQEVVTLVAAGLSNDEIAERLFVTPLTAKTHANRAMTKLGARDRAQLVVIAYQTGLARPDAP

Nucleotide


Download         Length: 672 bp        

>NTDB_id=99666 GZL_RS04215 WP_039629552.1 1110124..1110795(-) (vraR) [Streptomyces sp. 769]
ATGACGATCCGTGTCCTGCTCGCCGACGACCAGGCACTCCTGCGCGGCACCTTCCGGATGCTGCTCGATTCCGCCCCCGA
CATGGAGGTCGTCGCGGAGGCCGCAACGGGCCGCGAGGCCGTCGAACTGGCCCGCAGCCACCGCGCCGACCTCGTGCTGA
TGGACATCCGGATGCCCGACCTCGACGGCCTCGCAGCAACCAGGCTGATCAGCGATGACGAGAATCTTGCGGGGGTGAAG
GTCCTGGTGCTGACCACCTTCGAGAACGACGAGTACGTCGCGGAGGCACTACGCGCCGGAGCCAGCGGCTTCCTCGGCAA
GGGCATCAACCCTGACGAACTCCTCGATGCGATCCGCGTGGTCGCCGCCGGCGACTCCCTGCTCTCGCCCACCGCGACCA
AAGCCCTGATCGCCCGCTTCCTGGCCCAACCCGCACCACCCGACCGGGCTGCGGCACCGCTACTGGCCGCACTCACCCCA
CGGGAGCAGGAGGTGGTCACCCTGGTCGCAGCCGGGCTGTCCAACGACGAGATCGCCGAGCGCCTCTTCGTCACCCCGCT
CACCGCCAAGACCCACGCGAACCGCGCGATGACCAAGCTCGGCGCCCGAGACCGAGCCCAACTCGTGGTCATCGCCTACC
AGACAGGACTGGCCCGTCCCGACGCCCCATGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-212)

Response regulator receiver domain (Response_reg)

(5-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.443

98.206

0.368
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.368

Multiple sequence alignment