Detailed information NTG0996654

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: ELZ47_RS00615
• Genome accession: NZ_LR134002
• Coordinates: 111105..113654 (+)
• Length: 849 a.a.
• NCBI ID: WP_126434972.1
• Uniprot ID: -
• Organism: Streptococcus sanguinis strain NCTC 10904
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 106105..118654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ47_RS00595 (NCTC10904_00116)	-	107498..108016 (+)	519	WP_126434968.1	lantibiotic ABC transporter permease	-
ELZ47_RS00600 (NCTC10904_00117)	nrdI	108079..108567 (+)	489	WP_126434969.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
ELZ47_RS00605 (NCTC10904_00118)	argS	108600..110288 (-)	1689	WP_126434970.1	arginine--tRNA ligase	-
ELZ47_RS00610 (NCTC10904_00119)	argR	110589..111026 (+)	438	WP_126434971.1	arginine repressor	-
ELZ47_RS00615 (NCTC10904_00120)	hexA	111105..113654 (+)	2550	WP_126434972.1	DNA mismatch repair protein MutS	Machinery gene
ELZ47_RS00620 (NCTC10904_00121)	-	113839..114534 (+)	696	WP_126434973.1	zinc ribbon domain-containing protein	-
ELZ47_RS00625 (NCTC10904_00122)	-	114562..115872 (+)	1311	WP_126434974.1	SPFH domain-containing protein	-
ELZ47_RS00630 (NCTC10904_00123)	hexB	116076..118019 (+)	1944	WP_126434975.1	DNA mismatch repair endonuclease MutL	Machinery gene
ELZ47_RS00635 (NCTC10904_00124)	-	118068..118577 (-)	510	WP_164549528.1	RDD family protein	-

Sequence

Protein

• Length: 849 a.a.
• Molecular weight: 94836.09 Da
• Isoelectric Point: 4.9663

>NTDB_id=996654 ELZ47_RS00615 WP_126434972.1 111105..113654(+) (hexA) [Streptococcus sanguinis strain NCTC 10904]
MAVEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVNAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLV
ESGYKVAIAEQMEDPKEAKGVVKREVVQVITPGTVVDSSKPDSANNFLVALDYSEGLYGLAYMDLVTGEFQVTSLEDFAL
VCGEIRNLKAREVVLGYALPEAEEQVLAGQMNLLLSYVQTALDDVQLLGEELSPMERQAAGKLLEYVHRTQMRELSHLKK
AQHYEIKDFLQMDYATKASLDLTENARSGKKHGSLYWLMDETKTAMGGRMLRSWIQRPLIDEARISQRQNVVEVFLDHFF
ERSDLTESLKGVYDIERLASRVSFGKTNPKDLLQLAATLGNVPQIKAILQGIGSQHLARLIEGLDPIPELAGLISSAISP
DAPHIITEGNIIRTGFDETLDQYRLVLREGTGWIAELEVKERANSGISNLKIDYNKKDGYYFHVTNSQLAHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRVREEAGKYIQRLQALAQTLAAVDVLQSFAAVAEQGHLVRPVFT
SERRLEIEKGRHAVVEKVMGAQSYIPNSILLDQQTDIQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVPAQSASLPLFDA
IFTRIGAADDLVSGQSTFMVEMMEANRAIRQASERSLILFDELGRGTATYDGMALAQAIIEHIHHYTGAKTLFATHYHEL
TALEDSLEHLENVHVATLEKDGQVTFLHKIEPGPADKSYGIHVAKIAGLPDKLLERADSILSHLESQDTGLGSEFPATSR
QKQSRVAEQISLFAEESENPVLTELRDLDIYNMTPLEVMAAVAELKKKL

Nucleotide

• Length: 2550 bp

>NTDB_id=996654 ELZ47_RS00615 WP_126434972.1 111105..113654(+) (hexA) [Streptococcus sanguinis strain NCTC 10904]
ATGGCAGTAGAAAAGTTATCGCCCGGCATGCAGCAGTATTTGGATATCAAAAAGGACTATCCAGATGCTTTCTTGCTCTT
TCGGATGGGGGATTTTTATGAGTTGTTTTATGATGATGCGGTCAATGCCGCCCAGATTTTAGAGATTTCTCTCACCAGCC
GCAATAAAAATGCAGAAAATCCGATTCCCATGGCTGGAGTTCCCTATCATTCGGCACAGCAGTATATTGATGTTTTGGTC
GAGTCAGGCTATAAGGTAGCGATTGCGGAGCAGATGGAAGATCCCAAGGAAGCCAAGGGAGTTGTTAAGCGGGAGGTCGT
TCAGGTTATCACACCGGGGACGGTGGTGGACTCCAGTAAGCCGGACTCTGCGAATAACTTTCTGGTGGCTCTGGATTACT
CAGAGGGCCTCTATGGTCTGGCTTATATGGACTTGGTGACCGGTGAGTTTCAGGTGACTAGTTTAGAGGACTTTGCCTTG
GTCTGCGGGGAAATCCGTAATTTGAAGGCTAGGGAAGTGGTGCTGGGCTATGCCTTGCCAGAAGCTGAGGAGCAGGTCTT
GGCTGGGCAGATGAACCTTTTGCTGTCCTATGTACAGACAGCCTTGGATGATGTCCAGCTGCTGGGAGAGGAACTGTCTC
CGATGGAACGTCAGGCAGCGGGGAAATTGCTGGAGTATGTGCACCGGACCCAGATGAGGGAGCTCAGCCATTTGAAGAAG
GCCCAGCATTATGAAATCAAGGACTTTCTGCAAATGGACTATGCCACTAAGGCGAGTCTGGATTTGACAGAAAATGCTCG
CTCGGGCAAGAAGCACGGCAGTCTTTATTGGCTGATGGACGAGACTAAGACGGCCATGGGTGGCCGCATGCTGCGCTCTT
GGATCCAGCGTCCGCTGATTGATGAAGCGCGAATTAGCCAGCGACAGAATGTCGTTGAGGTTTTTCTGGATCATTTCTTT
GAGCGGAGTGATTTGACGGAGAGCCTCAAGGGAGTCTACGATATCGAGCGGCTGGCTAGTCGGGTGTCTTTTGGCAAGAC
CAATCCCAAGGATCTGCTGCAGCTGGCAGCTACATTGGGCAATGTGCCTCAGATTAAGGCTATCTTGCAAGGAATCGGTA
GCCAGCATCTAGCTCGTTTGATTGAGGGCTTGGATCCTATTCCAGAGTTGGCAGGCTTGATTAGCTCAGCTATTTCGCCG
GATGCGCCCCATATCATCACCGAGGGCAATATCATTCGGACCGGTTTTGATGAGACCTTGGATCAGTATAGGCTTGTGCT
GAGGGAGGGGACTGGATGGATTGCGGAGCTGGAAGTCAAAGAACGTGCTAACAGCGGCATCAGCAATCTGAAGATTGATT
ACAACAAAAAAGATGGTTACTATTTCCATGTGACCAATTCCCAGTTGGCTCATGTGCCTAGTCATTTCTTCCGCAAGGCG
ACCCTGAAAAATTCTGAGCGTTTCGGAACGGAGGAGCTGGCTCGGATTGAGGGAGAGATGTTGGAGGCGCGTGAAAAATC
TGCTAATTTGGAATACGAAATTTTCATGCGGGTTCGCGAGGAAGCTGGCAAATACATCCAGCGCTTGCAGGCCTTGGCAC
AAACACTGGCAGCTGTCGATGTTTTGCAGAGCTTTGCTGCAGTGGCGGAGCAGGGACATTTGGTGCGCCCTGTCTTTACT
TCGGAGCGCCGTCTGGAGATTGAAAAAGGTCGGCATGCTGTTGTGGAAAAGGTCATGGGTGCCCAGAGTTACATTCCAAA
TAGTATTCTGCTGGACCAGCAAACGGACATCCAGCTCATTACCGGGCCTAATATGAGCGGGAAGTCGACTTATATGCGCC
AGCTGGCTATCATCGTCATTATGGCACAGATGGGATCTTATGTGCCCGCTCAGTCTGCCAGTCTGCCACTATTCGATGCG
ATTTTTACTCGCATCGGTGCAGCGGATGATTTGGTGTCCGGCCAGTCTACCTTTATGGTGGAGATGATGGAGGCCAATCG
GGCCATTCGACAGGCCAGCGAGCGTTCGCTCATTCTCTTTGATGAGCTGGGGCGTGGAACGGCGACTTATGATGGGATGG
CGCTGGCTCAGGCTATTATCGAGCATATTCATCATTATACTGGGGCCAAGACCCTCTTTGCCACCCACTATCATGAGCTG
ACAGCCTTAGAGGATAGCTTGGAGCATTTGGAAAATGTCCATGTGGCAACCTTGGAAAAGGACGGGCAGGTGACTTTCCT
GCATAAGATTGAGCCGGGTCCGGCTGACAAGTCTTACGGAATCCATGTGGCGAAGATTGCCGGACTTCCTGATAAATTGC
TGGAGCGGGCAGATAGCATTTTGAGCCATCTGGAAAGTCAGGATACAGGACTAGGCTCAGAGTTTCCTGCTACATCCAGA
CAGAAGCAGTCACGAGTGGCTGAGCAGATCTCTCTTTTCGCAGAAGAGTCGGAAAATCCAGTCCTAACTGAACTCCGAGA
CTTGGACATATACAATATGACTCCTCTGGAAGTCATGGCGGCGGTAGCCGAGCTCAAGAAGAAGTTGTAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	77.621	100	0.776
mutS	Pseudomonas stutzeri strain ATCC 17587	38.623	100	0.39