Detailed information NTG0996542

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ELZ66_RS09085
• Genome accession: NZ_LR133933
• Coordinates: 2008753..2010027 (-)
• Length: 424 a.a.
• NCBI ID: WP_015444406.1
• Uniprot ID: Q5ZUE0
• Organism: Legionella pneumophila strain NCTC12180
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2003753..2015027

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ66_RS09075 (NCTC12180_01810)	-	2005658..2005936 (-)	279	WP_011214112.1	HU family DNA-binding protein	-
ELZ66_RS09080 (NCTC12180_01811)	lon	2006065..2008479 (-)	2415	WP_303260557.1	endopeptidase La	-
ELZ66_RS09085 (NCTC12180_01812)	clpX	2008753..2010027 (-)	1275	WP_015444406.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ELZ66_RS09090 (NCTC12180_01813)	clpP	2010168..2010812 (-)	645	WP_010947585.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
ELZ66_RS09095 (NCTC12180_01814)	tig	2010815..2012146 (-)	1332	WP_010947586.1	trigger factor	-
ELZ66_RS09120 (NCTC12180_01819)	-	2013008..2014234 (+)	1227	WP_010947587.1	site-specific integrase	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46583.17 Da
• Isoelectric Point: 5.1603

>NTDB_id=996542 ELZ66_RS09085 WP_015444406.1 2008753..2010027(-) (clpX) [Legionella pneumophila strain NCTC12180]
MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQ
QHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENII
QKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAAL
IDILTRPKNALTKQFQSLFKMEGSELEFRGEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESV
VNGLSKPILIYEQDEKKSASGSKD

Nucleotide

• Length: 1275 bp

>NTDB_id=996542 ELZ66_RS09085 WP_015444406.1 2008753..2010027(-) (clpX) [Legionella pneumophila strain NCTC12180]
ATGAGTAAATCCGGTAACGGAAATGGAGATAAGGTCTTATATTGCTCTTTTTGTGGCAAGAGTCAACATGAGGTAAAAAA
ATTAATTGCTGGACCTTCTGTGTTTGTTTGTGATGAATGTGTAGAGCTTTGTAATGATATTATTCGAGAAGAGACGCATG
AAACTCATGAAGAAACTGAGGCACGTCTACCGACACCAAAAGAAATATCTAACTTTCTCGATGAATACGTAATAGGGCAA
CAACATGCCAAAAAGGTTTTATCAGTAGCAGTATATAATCACTATAAGAGATTACAGCATAAAAGCGAGGATGGTGTTGA
GCTCGGCAAAAGTAATATTTTACTTATAGGACCTACTGGCAGTGGTAAGACTCTTTTAGCTCAAACCCTGGCGCGGATTC
TTAATGTTCCTTTTGCCATGGCTGATGCCACGACCCTTACTGAAGCTGGATATGTTGGCGAAGACGTTGAAAATATTATC
CAGAAGTTATTACAGAAGTGCGACTATGATGTAGATAAGGCACAGCAAGGTATTGTCTATATCGACGAAATCGATAAGAT
TTCACGCAAATCAGATAATCCATCTATCACCAGAGATGTTTCAGGAGAAGGTGTTCAACAAGCTTTACTGAAATTAATTG
AAGGTACTGTTGCATCTGTTCCACCGCAAGGTGGGCGAAAGCATCCACAGCAGGAATTTTTGCAGGTAGATACATCAAAT
ATTTTATTTATCTGTGGTGGCGCTTTTGCAGGTTTGGACAAAGTAATACGTGAACGCAGCGATAAATCAAGCATAGGTTT
TTCTGCTCAATTAAAAAGCAAAAAAAGCAGTAATGATGAAGTTTCAAAAGTTTTAGGTCAATTGGAATCAGATGATTTAA
TTAAATATGGGTTGATTCCCGAGTTTGTTGGACGTTTGCCTGTTGTAACCACTTTACAGGAACTTGATGAAGCGGCATTG
ATTGATATATTAACGAGACCTAAGAATGCTTTAACAAAGCAATTTCAATCACTTTTCAAAATGGAAGGTTCTGAACTTGA
GTTTAGAGGCGAAGCTTTGATTGCTATTGCTAAAAAGGCCCTCGAAAGAAAAATGGGCGCAAGAGGTTTGCGATCAATAC
TTGAAAATATTCTTTTAGACACTATGTATGACTTACCTTCCTTGGAAGGCGTGAATAAGGTTGTTATTGATGAGAGTGTA
GTGAATGGACTATCTAAACCGATTCTCATTTATGAACAGGATGAGAAAAAAAGTGCGTCTGGTAGTAAAGATTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-308)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (315-387)

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

3D structure

• AlphaFold DB: Q5ZUE0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.658	96.462	0.575
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.926	95.755	0.526