Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ELZ45_RS08350 Genome accession   NZ_LR133917
Coordinates   1669511..1670773 (-) Length   420 a.a.
NCBI ID   WP_000472306.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NCTC8317     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1664511..1675773
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ45_RS08325 (NCTC8317_01568) - 1664709..1665377 (-) 669 WP_000805940.1 uroporphyrinogen-III synthase -
  ELZ45_RS08330 (NCTC8317_01569) hemC 1665399..1666325 (-) 927 WP_001230228.1 hydroxymethylbilane synthase -
  ELZ45_RS08335 (NCTC8317_01570) - 1666367..1667182 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  ELZ45_RS08340 (NCTC8317_01571) hemA 1667204..1668550 (-) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  ELZ45_RS08345 (NCTC8317_01572) yihA 1668767..1669357 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ELZ45_RS08350 (NCTC8317_01573) clpX 1669511..1670773 (-) 1263 WP_000472306.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ELZ45_RS08355 (NCTC8317_01574) tig 1670924..1672225 (-) 1302 WP_000127573.1 trigger factor -
  ELZ45_RS08360 - 1672273..1672383 (-) 111 WP_001790560.1 hypothetical protein -
  ELZ45_RS08365 (NCTC8317_01575) - 1672388..1673317 (-) 930 WP_001280022.1 hypothetical protein -
  ELZ45_RS08370 (NCTC8317_01576) - 1673336..1673944 (-) 609 WP_000032657.1 NUDIX domain-containing protein -
  ELZ45_RS08380 (NCTC8317_01577) rplT 1674086..1674442 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  ELZ45_RS08385 (NCTC8317_01578) rpmI 1674489..1674689 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  ELZ45_RS08390 infC 1674718..1675245 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46287.44 Da        Isoelectric Point: 4.2645

>NTDB_id=996481 ELZ45_RS08350 WP_000472306.1 1669511..1670773(-) (clpX) [Staphylococcus aureus strain NCTC8317]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGSKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=996481 ELZ45_RS08350 WP_000472306.1 1669511..1670773(-) (clpX) [Staphylococcus aureus strain NCTC8317]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATGACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGATCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

67.168

95

0.638
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531