Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ABC965_RS13145 Genome accession   NZ_CP155063
Coordinates   2682744..2683409 (-) Length   221 a.a.
NCBI ID   WP_000697877.1    Uniprot ID   A0A0D1JN68
Organism   Staphylococcus aureus strain CC130-MRSA-XI     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2677744..2688409
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC965_RS13125 (ABC965_13125) - 2678197..2678310 (-) 114 WP_072491147.1 hypothetical protein -
  ABC965_RS13130 (ABC965_13130) - 2678986..2680986 (-) 2001 WP_000776722.1 ABC transporter permease -
  ABC965_RS13135 (ABC965_13135) - 2680983..2681738 (-) 756 WP_000923770.1 ABC transporter ATP-binding protein -
  ABC965_RS13140 (ABC965_13140) braS 2681846..2682733 (-) 888 WP_000143420.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  ABC965_RS13145 (ABC965_13145) braR 2682744..2683409 (-) 666 WP_000697877.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  ABC965_RS13150 (ABC965_13150) - 2683435..2683635 (-) 201 WP_000604725.1 hypothetical protein -
  ABC965_RS13155 (ABC965_13155) - 2683833..2685257 (+) 1425 WP_000953759.1 alkaline phosphatase -
  ABC965_RS13160 (ABC965_13160) - 2685327..2685437 (+) 111 WP_001791296.1 hypothetical protein -
  ABC965_RS13165 (ABC965_13165) - 2685540..2685995 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  ABC965_RS13170 (ABC965_13170) - 2686240..2687001 (-) 762 WP_000323448.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25415.49 Da        Isoelectric Point: 4.7961

>NTDB_id=996073 ABC965_RS13145 WP_000697877.1 2682744..2683409(-) (braR) [Staphylococcus aureus strain CC130-MRSA-XI]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=996073 ABC965_RS13145 WP_000697877.1 2682744..2683409(-) (braR) [Staphylococcus aureus strain CC130-MRSA-XI]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D1JN68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

100

100

1

Multiple sequence alignment